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The map label for this gene is dgdR [H]

Identifier: 110633653

GI number: 110633653

Start: 1392749

End: 1393648

Strand: Direct

Name: dgdR [H]

Synonym: Meso_1300

Alternate gene names: 110633653

Gene position: 1392749-1393648 (Clockwise)

Preceding gene: 110633652

Following gene: 110633654

Centisome position: 31.56

GC content: 60.78

Gene sequence:

>900_bases
ATGAACGCACCCCTGAATCACCCGCTGCCGCTGCTGGAGCTTGATGTCCTTCGAACCTTTGTCGCCATTGCCGAAACGGG
CAGCTTCACCGCGGCTTCCAATGCCGTCTTCCGCACTCCTTCGGCCGTTTCCATGCAGATCAAGAAATTGGAGGAACAGC
TCGGCCGCCCCGTTTTCGTGCGGGACGCGCGCTCCGTCACATTGACCTCCGACGGCGAGACGCTGCTGAGCTATGCGCGG
CGGCTGCTTGCGCTCAATCGCGAAGCGGTGTCGAAATTCGTGATGCCGGATATCAGCGGCATTGTGCGGCTTGGCTCTCC
GGATGATTTCGGCGAGCGCGTGCTTCCGAGCGTTCTGAAGCGCTTTGCCCAGACACATCCGGCCATTGCCGTCGATGTGG
TGATCGATCAAAGCGCCAGTTTGAGAAAGCGCATGGCCGCTCGTCAGCTCGACATCACGCTCATGACCTGCTCGGAAGAT
GTGGATCAGACGGGCATTGAGATCCTTCTGACAGAGCCGATCGTATGGGCGGGAGCGAAGGGGGGATGCGCCCATATGCG
AGAGCCCCTTCCGGTGTCTCTCTGGGAGGAGAGCTGCACCTGGCGCGCCAGAGCGGTGAAAGCGCTTTCAAAGCATAACC
GTGATTATCGCATCGCCTATATGAGCGCGCACGCGGCCGGGCAAAGAGCGGCGATCCTTTCAGATCTCGCGATCGCGCCC
CTTCCCAAATCCTTCATGGAGGATGACCTGGTCGAGCTTGGACCGAAGGACGGCCTGCCGGAACTCGGCAATTATCAGAT
CGCCATGGTCGTCACGCCCGATGCCGCCGCACCGGTAAGAGCCGCGGCCGACCATATCCGTGCAGCGTTCGACATGTTCA
ACGAGACCGGGCGGTTCTAG

Upstream 100 bases:

>100_bases
GGGCGGGCCGGGTTTCTGATGGATTGACTATGTGGGGGTTTTGTTATTCAATCAAACGCAATGATGTTATGATAACGTTC
AATGAAATTGAAGAGTCGTC

Downstream 100 bases:

>100_bases
GCGGCAGGAACCATTGGCGCGGCGTCTTTATTGGTAGGGGCGTTTTTCTTCGGGATATTGAGGAGGCGGCATGCAACGCG
AAGGCCGCGAGACGATCGCC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: 2,2-dialkylglycine decarboxylase repressor [H]

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MNAPLNHPLPLLELDVLRTFVAIAETGSFTAASNAVFRTPSAVSMQIKKLEEQLGRPVFVRDARSVTLTSDGETLLSYAR
RLLALNREAVSKFVMPDISGIVRLGSPDDFGERVLPSVLKRFAQTHPAIAVDVVIDQSASLRKRMAARQLDITLMTCSED
VDQTGIEILLTEPIVWAGAKGGCAHMREPLPVSLWEESCTWRARAVKALSKHNRDYRIAYMSAHAAGQRAAILSDLAIAP
LPKSFMEDDLVELGPKDGLPELGNYQIAMVVTPDAAAPVRAAADHIRAAFDMFNETGRF

Sequences:

>Translated_299_residues
MNAPLNHPLPLLELDVLRTFVAIAETGSFTAASNAVFRTPSAVSMQIKKLEEQLGRPVFVRDARSVTLTSDGETLLSYAR
RLLALNREAVSKFVMPDISGIVRLGSPDDFGERVLPSVLKRFAQTHPAIAVDVVIDQSASLRKRMAARQLDITLMTCSED
VDQTGIEILLTEPIVWAGAKGGCAHMREPLPVSLWEESCTWRARAVKALSKHNRDYRIAYMSAHAAGQRAAILSDLAIAP
LPKSFMEDDLVELGPKDGLPELGNYQIAMVVTPDAAAPVRAAADHIRAAFDMFNETGRF
>Mature_299_residues
MNAPLNHPLPLLELDVLRTFVAIAETGSFTAASNAVFRTPSAVSMQIKKLEEQLGRPVFVRDARSVTLTSDGETLLSYAR
RLLALNREAVSKFVMPDISGIVRLGSPDDFGERVLPSVLKRFAQTHPAIAVDVVIDQSASLRKRMAARQLDITLMTCSED
VDQTGIEILLTEPIVWAGAKGGCAHMREPLPVSLWEESCTWRARAVKALSKHNRDYRIAYMSAHAAGQRAAILSDLAIAP
LPKSFMEDDLVELGPKDGLPELGNYQIAMVVTPDAAAPVRAAADHIRAAFDMFNETGRF

Specific function: Not Known, Does Not Seem To Act On The Proton Translocating NADH Dehydrogenase Genes (Nuoa-N) Which Are Part Of The Lrha Operon. [C]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788626, Length=270, Percent_Identity=32.5925925925926, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI48994962, Length=161, Percent_Identity=29.8136645962733, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790208, Length=146, Percent_Identity=30.8219178082192, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1787806, Length=130, Percent_Identity=30.7692307692308, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1787601, Length=147, Percent_Identity=29.2517006802721, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1786713, Length=74, Percent_Identity=48.6486486486487, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI157672245, Length=147, Percent_Identity=31.9727891156463, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1786448, Length=116, Percent_Identity=34.4827586206897, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32676; Mature: 32676

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAPLNHPLPLLELDVLRTFVAIAETGSFTAASNAVFRTPSAVSMQIKKLEEQLGRPVFV
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEECCHHHHHHHHHHHHHHCCCEEE
RDARSVTLTSDGETLLSYARRLLALNREAVSKFVMPDISGIVRLGSPDDFGERVLPSVLK
ECCCEEEEECCCHHHHHHHHHHHHHCHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHH
RFAQTHPAIAVDVVIDQSASLRKRMAARQLDITLMTCSEDVDQTGIEILLTEPIVWAGAK
HHHHCCCCEEEEEEECCCHHHHHHHHHHHHCEEEEECCCCCCCCCCEEEEECCEEEECCC
GGCAHMREPLPVSLWEESCTWRARAVKALSKHNRDYRIAYMSAHAAGQRAAILSDLAIAP
CCHHHCCCCCCHHHHHHCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHCC
LPKSFMEDDLVELGPKDGLPELGNYQIAMVVTPDAAAPVRAAADHIRAAFDMFNETGRF
CCHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNAPLNHPLPLLELDVLRTFVAIAETGSFTAASNAVFRTPSAVSMQIKKLEEQLGRPVFV
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEECCHHHHHHHHHHHHHHCCCEEE
RDARSVTLTSDGETLLSYARRLLALNREAVSKFVMPDISGIVRLGSPDDFGERVLPSVLK
ECCCEEEEECCCHHHHHHHHHHHHHCHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHH
RFAQTHPAIAVDVVIDQSASLRKRMAARQLDITLMTCSEDVDQTGIEILLTEPIVWAGAK
HHHHCCCCEEEEEEECCCHHHHHHHHHHHHCEEEEECCCCCCCCCCEEEEECCEEEECCC
GGCAHMREPLPVSLWEESCTWRARAVKALSKHNRDYRIAYMSAHAAGQRAAILSDLAIAP
CCHHHCCCCCCHHHHHHCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHCC
LPKSFMEDDLVELGPKDGLPELGNYQIAMVVTPDAAAPVRAAADHIRAAFDMFNETGRF
CCHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2180928 [H]