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The map label for this gene is speB [H]

Identifier: 110633515

GI number: 110633515

Start: 1271645

End: 1272592

Strand: Reverse

Name: speB [H]

Synonym: Meso_1162

Alternate gene names: 110633515

Gene position: 1272592-1271645 (Counterclockwise)

Preceding gene: 110633516

Following gene: 110633514

Centisome position: 28.84

GC content: 65.61

Gene sequence:

>948_bases
ATGCCATCCAAGACCATCGACCACGCCTTCACCGCGCGGCAGATCACGGGAGCCGCCGGCGACCCGACTTACGCGGGCGC
CCTCTCCTTCATGCGCCGCAAATTCACAAAGGATGTGAAGGGCGCGGATGCCGTGGTGTGGGGCATACCGTTCGATGCCG
CGGTTTCGAACCGGCCGGGCGCGCGCTTCGGGCCGCAGGCGATCCGCCGCGCCTCCGTCATCTTCGACAACGACCCGCAA
TACCCGTTTCACCTCGATCTGTTCGATACGCTCGCCGTGGTCGACTATGGCGATTGCCTGCTCGACTATGGCCGTCACGA
CCTTACTCCCGCGGCCATAGAGACCGAGGCTTCGAAGATCCTGGAATCGGGCGCCTTCCTCGTCACACTCGGCGGCGACC
ATTTCGTCACCTGGCCGCTGCTCAGGGCGCATGCGGCCCGACACGGACCCCTCGCCCTCGTCCAGTTCGATGCGCATCAG
GACACCTGGTGGGACGACGGCAACCGTATCGACCACGGCTCCTTCGTCGGGCGGGCGGTACGGGACGGCGTGATCGATCC
CGCCCGCTCCATCCAGGTCGGCATCCGCACCCATGCGCCGGAGGATTGCGGCCTCAAGATCGTGCATGGCTACGACCTTG
AGGAAATTCGTGCCGCCGAAATCGCGCGCATGATCGCCGAGCGGGTGGGCGACGCGCCGGCCTATATCACCTTCGATATC
GATTGCCTGGACCCCGCCTTTGCGCCGGGCACGGGCACGCCGGTTGCGGGCGGGCCTTCGACAGCGAAGATGCTCTCCAT
CCTTCGCCAGCTCGGCGGGCTCAACATCGTGGGTGCTGACGTGGTGGAGGTTTCGCCCCCTTATGACCATGCCGATGTCA
CGGCCATTGCCGGGGCCTCCATCGCCATGCACTATCTGGGGCTTCTGGCGGAGAAGCGACGGCCATAA

Upstream 100 bases:

>100_bases
CAGTACAGGACGGAAAAAGCGGGCTTCGGCCCGCTTTTTTGTTGCACGCACGCAAAGCCCCCCATAGCCATAGGCGGCCT
TTTCGGAGGGAGTTACCGCG

Downstream 100 bases:

>100_bases
TCCTCAAGTTATGGTTCAAGAAGTTTTCGGATTGATTCCGGAACGCTTCTCAACCATTTGAAGGCTGACTCTTTTTCGGG
CGCGAACAATATGACGGCAA

Product: agmatinase

Products: NA

Alternate protein names: Agmatine ureohydrolase; AUH [H]

Number of amino acids: Translated: 315; Mature: 314

Protein sequence:

>315_residues
MPSKTIDHAFTARQITGAAGDPTYAGALSFMRRKFTKDVKGADAVVWGIPFDAAVSNRPGARFGPQAIRRASVIFDNDPQ
YPFHLDLFDTLAVVDYGDCLLDYGRHDLTPAAIETEASKILESGAFLVTLGGDHFVTWPLLRAHAARHGPLALVQFDAHQ
DTWWDDGNRIDHGSFVGRAVRDGVIDPARSIQVGIRTHAPEDCGLKIVHGYDLEEIRAAEIARMIAERVGDAPAYITFDI
DCLDPAFAPGTGTPVAGGPSTAKMLSILRQLGGLNIVGADVVEVSPPYDHADVTAIAGASIAMHYLGLLAEKRRP

Sequences:

>Translated_315_residues
MPSKTIDHAFTARQITGAAGDPTYAGALSFMRRKFTKDVKGADAVVWGIPFDAAVSNRPGARFGPQAIRRASVIFDNDPQ
YPFHLDLFDTLAVVDYGDCLLDYGRHDLTPAAIETEASKILESGAFLVTLGGDHFVTWPLLRAHAARHGPLALVQFDAHQ
DTWWDDGNRIDHGSFVGRAVRDGVIDPARSIQVGIRTHAPEDCGLKIVHGYDLEEIRAAEIARMIAERVGDAPAYITFDI
DCLDPAFAPGTGTPVAGGPSTAKMLSILRQLGGLNIVGADVVEVSPPYDHADVTAIAGASIAMHYLGLLAEKRRP
>Mature_314_residues
PSKTIDHAFTARQITGAAGDPTYAGALSFMRRKFTKDVKGADAVVWGIPFDAAVSNRPGARFGPQAIRRASVIFDNDPQY
PFHLDLFDTLAVVDYGDCLLDYGRHDLTPAAIETEASKILESGAFLVTLGGDHFVTWPLLRAHAARHGPLALVQFDAHQD
TWWDDGNRIDHGSFVGRAVRDGVIDPARSIQVGIRTHAPEDCGLKIVHGYDLEEIRAAEIARMIAERVGDAPAYITFDID
CLDPAFAPGTGTPVAGGPSTAKMLSILRQLGGLNIVGADVVEVSPPYDHADVTAIAGASIAMHYLGLLAEKRRP

Specific function: Catalyzes the formation of putrescine from agmatine [H]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family. Agmatinase subfamily [H]

Homologues:

Organism=Homo sapiens, GI37537722, Length=295, Percent_Identity=37.6271186440678, Blast_Score=192, Evalue=3e-49,
Organism=Homo sapiens, GI4502215, Length=297, Percent_Identity=29.6296296296296, Blast_Score=82, Evalue=6e-16,
Organism=Escherichia coli, GI1789306, Length=292, Percent_Identity=42.8082191780822, Blast_Score=226, Evalue=2e-60,
Organism=Saccharomyces cerevisiae, GI6325146, Length=244, Percent_Identity=26.6393442622951, Blast_Score=63, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005925
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.11 [H]

Molecular weight: Translated: 33890; Mature: 33758

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: PS00147 ARGINASE_1 ; PS00148 ARGINASE_2 ; PS01053 ARGINASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSKTIDHAFTARQITGAAGDPTYAGALSFMRRKFTKDVKGADAVVWGIPFDAAVSNRPG
CCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHCCCCCC
ARFGPQAIRRASVIFDNDPQYPFHLDLFDTLAVVDYGDCLLDYGRHDLTPAAIETEASKI
CCCCHHHHHHHHEEECCCCCCCEEECHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
LESGAFLVTLGGDHFVTWPLLRAHAARHGPLALVQFDAHQDTWWDDGNRIDHGSFVGRAV
HHCCCEEEEECCCCEEHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCEECCHHHHHHHH
RDGVIDPARSIQVGIRTHAPEDCGLKIVHGYDLEEIRAAEIARMIAERVGDAPAYITFDI
HCCCCCCCHHEEEEEECCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCEEEEEEE
DCLDPAFAPGTGTPVAGGPSTAKMLSILRQLGGLNIVGADVVEVSPPYDHADVTAIAGAS
EECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEECCCEEEECCCCCCCCHHHHHHHH
IAMHYLGLLAEKRRP
HHHHHHHHHHHCCCC
>Mature Secondary Structure 
PSKTIDHAFTARQITGAAGDPTYAGALSFMRRKFTKDVKGADAVVWGIPFDAAVSNRPG
CCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHCCCCCC
ARFGPQAIRRASVIFDNDPQYPFHLDLFDTLAVVDYGDCLLDYGRHDLTPAAIETEASKI
CCCCHHHHHHHHEEECCCCCCCEEECHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
LESGAFLVTLGGDHFVTWPLLRAHAARHGPLALVQFDAHQDTWWDDGNRIDHGSFVGRAV
HHCCCEEEEECCCCEEHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCEECCHHHHHHHH
RDGVIDPARSIQVGIRTHAPEDCGLKIVHGYDLEEIRAAEIARMIAERVGDAPAYITFDI
HCCCCCCCHHEEEEEECCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCEEEEEEE
DCLDPAFAPGTGTPVAGGPSTAKMLSILRQLGGLNIVGADVVEVSPPYDHADVTAIAGAS
EECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEECCCEEEECCCCCCCCHHHHHHHH
IAMHYLGLLAEKRRP
HHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14500782 [H]