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The map label for this gene is argC

Identifier: 110633514

GI number: 110633514

Start: 1270622

End: 1271554

Strand: Reverse

Name: argC

Synonym: Meso_1161

Alternate gene names: 110633514

Gene position: 1271554-1270622 (Counterclockwise)

Preceding gene: 110633515

Following gene: 110633512

Centisome position: 28.82

GC content: 64.95

Gene sequence:

>933_bases
ATGACGGCAAAGATCTTCATCGACGGCGAACACGGCACCACGGGGCTCCAGATCCGCGCCCGCCTTGGAGAGCGCAGGGA
TATCGAACTCCTCTCGATCCCCGTGGAGCGGCGTAAGGACCCAGCCGCCCGCGCAGAGTTCCTGAACGCGGCCGATATAG
CCATTCTCTGCCTGCCGGACGATGCGGCGCGCGAAAGCGTCTCGCTCATCGCGAACGACACGACGCGCGTGATCGACGCC
TCCACCGCGTACCGCGTGAGCGAAGGCTGGGCCTATGGCTTTCCCGAAATGGACAAGAGCCAGTCCAAGGCCATTGCGCA
GGCGAAGCGTGTCGCCAATCCCGGCTGCTGGCCGCAGGGTCCAATCGCCCTTCTGCGTCCGCTCGTCTCCGCCGGTCTGC
TGCCAGCGGATTTCCCGGTCACGATCAACGGCATTACCGGCTATTCCGGCGGCGGCCGCTCGATGATCGAGGACTATGAG
GGCAAGGGCGAGGACGCGCCGGAATTCTTCCCCTACGGCCTCACACTCAGCCACAAGCACCTGCCGGAGCTGCGCACCTA
CGCCAAGCTTGCGCGCGACCCGCTGATGCAGCCGGTGGTCGGCAATTTTGCCCAGGGCATGATCACTATGGTGCCGCTTC
AGCTCGGCCACCTTCCCCGCGTGCCCAAAGGCGAGGAGCTGCATGCGGCCATAGCCGATCACTATGCGGGCATCGAGGGG
AGCGCCGTCGAGGTTGCGCCGTTCCAGGCCATCGAGCGTTCGCCGGAAATCGAGCCCGAGCGCTACAACGACACGAATAC
CATGCGGCTCTACGTCTTCGCCAATGATGCGCGGGCGCAGGCGCTGCTCTTGGCTGTCTATGACAATCTCGGCAAGGGCG
CGTCGGGCGCTGCCGTGCAGAATCTCGACCTGATGCTTTCCGGGCTCCGCTGA

Upstream 100 bases:

>100_bases
ACGGCCATAATCCTCAAGTTATGGTTCAAGAAGTTTTCGGATTGATTCCGGAACGCTTCTCAACCATTTGAAGGCTGACT
CTTTTTCGGGCGCGAACAAT

Downstream 100 bases:

>100_bases
CGAATGCTCCGCGGCCGCTCGCGCCCGCTTCGTCGGTATGCGCCTCAGCGGCGAAAGCCGAATTCTGCTGCTAAAGAACT
AAGCGGCCGCCTGCATGAAC

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase

Number of amino acids: Translated: 310; Mature: 309

Protein sequence:

>310_residues
MTAKIFIDGEHGTTGLQIRARLGERRDIELLSIPVERRKDPAARAEFLNAADIAILCLPDDAARESVSLIANDTTRVIDA
STAYRVSEGWAYGFPEMDKSQSKAIAQAKRVANPGCWPQGPIALLRPLVSAGLLPADFPVTINGITGYSGGGRSMIEDYE
GKGEDAPEFFPYGLTLSHKHLPELRTYAKLARDPLMQPVVGNFAQGMITMVPLQLGHLPRVPKGEELHAAIADHYAGIEG
SAVEVAPFQAIERSPEIEPERYNDTNTMRLYVFANDARAQALLLAVYDNLGKGASGAAVQNLDLMLSGLR

Sequences:

>Translated_310_residues
MTAKIFIDGEHGTTGLQIRARLGERRDIELLSIPVERRKDPAARAEFLNAADIAILCLPDDAARESVSLIANDTTRVIDA
STAYRVSEGWAYGFPEMDKSQSKAIAQAKRVANPGCWPQGPIALLRPLVSAGLLPADFPVTINGITGYSGGGRSMIEDYE
GKGEDAPEFFPYGLTLSHKHLPELRTYAKLARDPLMQPVVGNFAQGMITMVPLQLGHLPRVPKGEELHAAIADHYAGIEG
SAVEVAPFQAIERSPEIEPERYNDTNTMRLYVFANDARAQALLLAVYDNLGKGASGAAVQNLDLMLSGLR
>Mature_309_residues
TAKIFIDGEHGTTGLQIRARLGERRDIELLSIPVERRKDPAARAEFLNAADIAILCLPDDAARESVSLIANDTTRVIDAS
TAYRVSEGWAYGFPEMDKSQSKAIAQAKRVANPGCWPQGPIALLRPLVSAGLLPADFPVTINGITGYSGGGRSMIEDYEG
KGEDAPEFFPYGLTLSHKHLPELRTYAKLARDPLMQPVVGNFAQGMITMVPLQLGHLPRVPKGEELHAAIADHYAGIEGS
AVEVAPFQAIERSPEIEPERYNDTNTMRLYVFANDARAQALLLAVYDNLGKGASGAAVQNLDLMLSGLR

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 2 subfamily

Homologues:

Organism=Escherichia coli, GI1790396, Length=207, Percent_Identity=25.6038647342995, Blast_Score=67, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6320913, Length=275, Percent_Identity=28, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGC_MESSB (Q11J68)

Other databases:

- EMBL:   CP000390
- RefSeq:   YP_673722.1
- ProteinModelPortal:   Q11J68
- STRING:   Q11J68
- GeneID:   4179620
- GenomeReviews:   CP000390_GR
- KEGG:   mes:Meso_1161
- NMPDR:   fig|266779.1.peg.2424
- eggNOG:   COG0002
- HOGENOM:   HBG294213
- OMA:   PIFVPSV
- ProtClustDB:   PRK11863
- BioCyc:   MSP266779:MESO_1161-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01110
- InterPro:   IPR010136
- InterPro:   IPR016040
- InterPro:   IPR000534
- Gene3D:   G3DSA:3.40.50.720
- SMART:   SM00859
- TIGRFAMs:   TIGR01851

Pfam domain/function: PF01118 Semialdhyde_dh

EC number: =1.2.1.38

Molecular weight: Translated: 33594; Mature: 33462

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: PS01224 ARGC

Important sites: ACT_SITE 116-116

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAKIFIDGEHGTTGLQIRARLGERRDIELLSIPVERRKDPAARAEFLNAADIAILCLPD
CCEEEEEECCCCCCCEEEEEECCCCCCEEEEECCHHHCCCHHHHHHHCCCCCEEEEECCC
DAARESVSLIANDTTRVIDASTAYRVSEGWAYGFPEMDKSQSKAIAQAKRVANPGCWPQG
HHHHHHEEEEECCCCEEEECCCCEEECCCEECCCCCCCCHHHHHHHHHHHHCCCCCCCCC
PIALLRPLVSAGLLPADFPVTINGITGYSGGGRSMIEDYEGKGEDAPEFFPYGLTLSHKH
HHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCHHHHHCCCCCCCCCCCCCCCEEECCCC
LPELRTYAKLARDPLMQPVVGNFAQGMITMVPLQLGHLPRVPKGEELHAAIADHYAGIEG
CHHHHHHHHHHHCHHHHHHHHHHHHHHHEEEHHHHCCCCCCCCCCHHHHHHHHHHCCCCC
SAVEVAPFQAIERSPEIEPERYNDTNTMRLYVFANDARAQALLLAVYDNLGKGASGAAVQ
CEEEECHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCCHHEEHEEEHHCCCCCCCCCHHH
NLDLMLSGLR
HHHHHHCCCC
>Mature Secondary Structure 
TAKIFIDGEHGTTGLQIRARLGERRDIELLSIPVERRKDPAARAEFLNAADIAILCLPD
CEEEEEECCCCCCCEEEEEECCCCCCEEEEECCHHHCCCHHHHHHHCCCCCEEEEECCC
DAARESVSLIANDTTRVIDASTAYRVSEGWAYGFPEMDKSQSKAIAQAKRVANPGCWPQG
HHHHHHEEEEECCCCEEEECCCCEEECCCEECCCCCCCCHHHHHHHHHHHHCCCCCCCCC
PIALLRPLVSAGLLPADFPVTINGITGYSGGGRSMIEDYEGKGEDAPEFFPYGLTLSHKH
HHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCHHHHHCCCCCCCCCCCCCCCEEECCCC
LPELRTYAKLARDPLMQPVVGNFAQGMITMVPLQLGHLPRVPKGEELHAAIADHYAGIEG
CHHHHHHHHHHHCHHHHHHHHHHHHHHHEEEHHHHCCCCCCCCCCHHHHHHHHHHCCCCC
SAVEVAPFQAIERSPEIEPERYNDTNTMRLYVFANDARAQALLLAVYDNLGKGASGAAVQ
CEEEECHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCCHHEEHEEEHHCCCCCCCCCHHH
NLDLMLSGLR
HHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA