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The map label for this gene is ribE [H]

Identifier: 110633490

GI number: 110633490

Start: 1244775

End: 1245389

Strand: Direct

Name: ribE [H]

Synonym: Meso_1137

Alternate gene names: 110633490

Gene position: 1244775-1245389 (Clockwise)

Preceding gene: 110633489

Following gene: 110633491

Centisome position: 28.21

GC content: 62.28

Gene sequence:

>615_bases
ATGTTCACGGGCATCGTGACGGATGTGGGCGCGATTCAGCGCATTGTGCCGCTTCCCAAGGGGTTGCGGCTGCGGATCGG
GACCAATTACGACCCGCAGAGCATCGATATCGGCGCATCAATCGCCTGTGCCGGCGTGTGCCTGACGGTTGTGGCCCTGC
CCGAGGGCGGTTCGAACCAGCGTTGGTGCGAGGTAGAGGCATGGGATGAGGCCCTTCAACTCACGACCGTTTCCGAATGG
CATGACGGCACGCGCATCAATTTGGAGCGCGCGCTAAAGATCGGCGACGAGCTGGGTGGACATATCGTCTCGGGCCATGT
GGACGGCACGGCCACCATCGTCGAGCGCAGGGAAGAGGGCGAAGCCGTGCGCTTTGTGCTCGAAGCGCCGCGGGAACTCG
CAAAATTCATCGCCCCCAAAGGCTCCGTAGCGCTGGACGGCACGTCTCTCACGGTGAACCGCGTCGATGGCAATCGTTTC
AACGTGCTGCTTATCCATCATTCGCTCGACGTCACGACCTGGGGGGAGCGGCAGGTGGGTCAAAAGGTCAATCTTGAGGT
CGATACCATGGCCCGCTACGCCGCGCGTCTTGCGGAGGCGGCGAAAGAGGCCTAA

Upstream 100 bases:

>100_bases
TTGCCTCGCCGGTTGACCTCGACCATATCCCATCGGGTTTCGCCAAGCGGCGCGAGGCGCGCTTCGGCGAAGATCTCTAT
TTCGAATATGTGAGGGCGTA

Downstream 100 bases:

>100_bases
TCGGCTGCTCTCCCGGAGATAAAGATGACAGACAAGACGAAACTCCTCATCGTCGAAGCGCGCTTTTACGATGACTTGGC
CGATGGCCTGCTGAATTCCG

Product: riboflavin synthase subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 204; Mature: 204

Protein sequence:

>204_residues
MFTGIVTDVGAIQRIVPLPKGLRLRIGTNYDPQSIDIGASIACAGVCLTVVALPEGGSNQRWCEVEAWDEALQLTTVSEW
HDGTRINLERALKIGDELGGHIVSGHVDGTATIVERREEGEAVRFVLEAPRELAKFIAPKGSVALDGTSLTVNRVDGNRF
NVLLIHHSLDVTTWGERQVGQKVNLEVDTMARYAARLAEAAKEA

Sequences:

>Translated_204_residues
MFTGIVTDVGAIQRIVPLPKGLRLRIGTNYDPQSIDIGASIACAGVCLTVVALPEGGSNQRWCEVEAWDEALQLTTVSEW
HDGTRINLERALKIGDELGGHIVSGHVDGTATIVERREEGEAVRFVLEAPRELAKFIAPKGSVALDGTSLTVNRVDGNRF
NVLLIHHSLDVTTWGERQVGQKVNLEVDTMARYAARLAEAAKEA
>Mature_204_residues
MFTGIVTDVGAIQRIVPLPKGLRLRIGTNYDPQSIDIGASIACAGVCLTVVALPEGGSNQRWCEVEAWDEALQLTTVSEW
HDGTRINLERALKIGDELGGHIVSGHVDGTATIVERREEGEAVRFVLEAPRELAKFIAPKGSVALDGTSLTVNRVDGNRF
NVLLIHHSLDVTTWGERQVGQKVNLEVDTMARYAARLAEAAKEA

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The alpha subunit catalyze

COG id: COG0307

COG function: function code H; Riboflavin synthase alpha chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 lumazine-binding repeats [H]

Homologues:

Organism=Escherichia coli, GI1787952, Length=210, Percent_Identity=33.8095238095238, Blast_Score=100, Evalue=9e-23,
Organism=Saccharomyces cerevisiae, GI6319733, Length=207, Percent_Identity=36.231884057971, Blast_Score=112, Evalue=5e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001783
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00677 Lum_binding [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 22107; Mature: 22107

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTGIVTDVGAIQRIVPLPKGLRLRIGTNYDPQSIDIGASIACAGVCLTVVALPEGGSNQ
CCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCEECCCHHHHHHHEEEEEECCCCCCCC
RWCEVEAWDEALQLTTVSEWHDGTRINLERALKIGDELGGHIVSGHVDGTATIVERREEG
EEEEEEHHHHHEEEEEECCCCCCCEEEHHHHHHHHHHCCCEEEECCCCCEEEEEHHHCCC
EAVRFVLEAPRELAKFIAPKGSVALDGTSLTVNRVDGNRFNVLLIHHSLDVTTWGERQVG
HHHHHHHHCHHHHHHHHCCCCCEEECCCEEEEEECCCCEEEEEEEEECCCEEECCCHHCC
QKVNLEVDTMARYAARLAEAAKEA
CCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFTGIVTDVGAIQRIVPLPKGLRLRIGTNYDPQSIDIGASIACAGVCLTVVALPEGGSNQ
CCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCEECCCHHHHHHHEEEEEECCCCCCCC
RWCEVEAWDEALQLTTVSEWHDGTRINLERALKIGDELGGHIVSGHVDGTATIVERREEG
EEEEEEHHHHHEEEEEECCCCCCCEEEHHHHHHHHHHCCCEEEECCCCCEEEEEHHHCCC
EAVRFVLEAPRELAKFIAPKGSVALDGTSLTVNRVDGNRFNVLLIHHSLDVTTWGERQVG
HHHHHHHHCHHHHHHHHCCCCCEEECCCEEEEEECCCCEEEEEEEEECCCEEECCCHHCC
QKVNLEVDTMARYAARLAEAAKEA
CCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8144477 [H]