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The map label for this gene is dgoD [H]

Identifier: 110633428

GI number: 110633428

Start: 1177776

End: 1178960

Strand: Direct

Name: dgoD [H]

Synonym: Meso_1074

Alternate gene names: 110633428

Gene position: 1177776-1178960 (Clockwise)

Preceding gene: 110633427

Following gene: 110633429

Centisome position: 26.69

GC content: 62.11

Gene sequence:

>1185_bases
ATGAAGATTACCGCGGTCGAAACCCTCTATTGCAACGCAGGATGGCGCAACCTTTCCTTCCTGAAAATTTCCACCGACGA
GGGGCTGGTCGGCTGGGCGGAGTTTCCGGAAAATCACATCAACAATGTACTCTCTCCGCTCGTCCGCCACATGGGCCAGC
AGATCCTCGGCGAAGATCCGCGGCGCATACATCCGGTGATCGACCGCCTCCGCCGCGCGGCCTGGGGTGTGCCCTTCGGT
GCGGTCTCGCGCGCGATCGGCGCGATCGAGAACGCACTGGTCGACATCAAGGCAAAGGCTATCGGCGTGCCGGCCTATGA
ACTTATCGGCGGCAGGATGCGCGATGATATCCGTATGTACTGGTCGCATTGCGGTTCCTATCATGTGACCAACTGGAAGG
ATCTCGGCGTTCCGCGCATCACCTCGCTCGATGATGTGAAGTCGCTGGGGCGGCAGGTGCGGGAGTCCGGCTATCACGCG
CTCAAGACCAACCTCATGATGTTCGACAGGCCCGAACCTTACATGTACCGTCCGGGCTTCGCCGGCGGTTCGGGTGACCC
CGACCGCAATCCGCTTCGCTCCGCCATCTCGGCGGCGGTCGACCAGATGACAGCCTTCCGCGAGGGCGCGGGGCCCGATA
TTGGCCTTAAACTGGACGTGAATTTCAATTTCCGCCCCGAGGGCTATATCCGTCTCGCCCATGCCCTGGAGCCCGTGGAC
CTCGACTGGCTGGAAATCGACAATTTCGACGCCAAGGCCGTCGCCCAGGTTCGCCGGGCCAGCCGCATCCCCATCGCCTC
CTGCGAGACGCTGAGCGGCAGGCGCCAGCTTCGGCCCTATCTGGAGGAGCAGGCGGTCGATGTCGTGATCATCGATGTGC
CGTGGAACGGCATCTATGAAGCAATGCGGATGGCCGCCTTGGCCGACAGTTTTGAGGTCAATGTCGCAACCCATAATTTC
TGCGGGCCGATCGCCACGCTCATCAGTGCGCATTTCTGCGCCGCCGTTCCCAATTTCCGCGTCATGGAAATGGATGTGGT
ACAGGTCCCGTGGACGAACGACCTCATTACCAATCCGCCCACGATCGAGAGGGGCTATATGCGCCTGCCCGACGGGCCGG
GTTGGGGCGCGGATGTGAACGAGGAGGCGCTCCGGGCGCATCCGCCCGTAGCCGCCAAGCATTGA

Upstream 100 bases:

>100_bases
GCTGCCGAGACGGAAGCCTTCGCGCGCGGCGAATATGAAGCATTGAAGAAGCTTTGGGACCAGGATCCCTGGATCAAGGA
CTAGGAGGCTGGCGAGTACG

Downstream 100 bases:

>100_bases
TTTTGCTCAGTTATTACGCAGTTGGGGAATGCTCATGAAACCCGAGGTGATTGTCCGTGTGCCCTTTCCGCCCGAAAGCA
TCGCGCTTTTGGAGGAGGAT

Product: mandelate racemase/muconate lactonizing-like protein

Products: NA

Alternate protein names: GalD [H]

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MKITAVETLYCNAGWRNLSFLKISTDEGLVGWAEFPENHINNVLSPLVRHMGQQILGEDPRRIHPVIDRLRRAAWGVPFG
AVSRAIGAIENALVDIKAKAIGVPAYELIGGRMRDDIRMYWSHCGSYHVTNWKDLGVPRITSLDDVKSLGRQVRESGYHA
LKTNLMMFDRPEPYMYRPGFAGGSGDPDRNPLRSAISAAVDQMTAFREGAGPDIGLKLDVNFNFRPEGYIRLAHALEPVD
LDWLEIDNFDAKAVAQVRRASRIPIASCETLSGRRQLRPYLEEQAVDVVIIDVPWNGIYEAMRMAALADSFEVNVATHNF
CGPIATLISAHFCAAVPNFRVMEMDVVQVPWTNDLITNPPTIERGYMRLPDGPGWGADVNEEALRAHPPVAAKH

Sequences:

>Translated_394_residues
MKITAVETLYCNAGWRNLSFLKISTDEGLVGWAEFPENHINNVLSPLVRHMGQQILGEDPRRIHPVIDRLRRAAWGVPFG
AVSRAIGAIENALVDIKAKAIGVPAYELIGGRMRDDIRMYWSHCGSYHVTNWKDLGVPRITSLDDVKSLGRQVRESGYHA
LKTNLMMFDRPEPYMYRPGFAGGSGDPDRNPLRSAISAAVDQMTAFREGAGPDIGLKLDVNFNFRPEGYIRLAHALEPVD
LDWLEIDNFDAKAVAQVRRASRIPIASCETLSGRRQLRPYLEEQAVDVVIIDVPWNGIYEAMRMAALADSFEVNVATHNF
CGPIATLISAHFCAAVPNFRVMEMDVVQVPWTNDLITNPPTIERGYMRLPDGPGWGADVNEEALRAHPPVAAKH
>Mature_394_residues
MKITAVETLYCNAGWRNLSFLKISTDEGLVGWAEFPENHINNVLSPLVRHMGQQILGEDPRRIHPVIDRLRRAAWGVPFG
AVSRAIGAIENALVDIKAKAIGVPAYELIGGRMRDDIRMYWSHCGSYHVTNWKDLGVPRITSLDDVKSLGRQVRESGYHA
LKTNLMMFDRPEPYMYRPGFAGGSGDPDRNPLRSAISAAVDQMTAFREGAGPDIGLKLDVNFNFRPEGYIRLAHALEPVD
LDWLEIDNFDAKAVAQVRRASRIPIASCETLSGRRQLRPYLEEQAVDVVIIDVPWNGIYEAMRMAALADSFEVNVATHNF
CGPIATLISAHFCAAVPNFRVMEMDVVQVPWTNDLITNPPTIERGYMRLPDGPGWGADVNEEALRAHPPVAAKH

Specific function: Catalyzes the dehydration of D-galactonate to 2-keto-3- deoxy-D-galactonate [H]

COG id: COG4948

COG function: function code MR; L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily [H]

Homologues:

Organism=Escherichia coli, GI48994953, Length=390, Percent_Identity=26.4102564102564, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1787864, Length=402, Percent_Identity=25.3731343283582, Blast_Score=102, Evalue=5e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018110
- InterPro:   IPR013342
- InterPro:   IPR013341
- InterPro:   IPR001354 [H]

Pfam domain/function: PF01188 MR_MLE; PF02746 MR_MLE_N [H]

EC number: =4.2.1.6 [H]

Molecular weight: Translated: 43891; Mature: 43891

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKITAVETLYCNAGWRNLSFLKISTDEGLVGWAEFPENHINNVLSPLVRHMGQQILGEDP
CEEEEEEEEEECCCCCCEEEEEEECCCCCEEHHHCCHHHHHHHHHHHHHHHHHHHHCCCC
RRIHPVIDRLRRAAWGVPFGAVSRAIGAIENALVDIKAKAIGVPAYELIGGRMRDDIRMY
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHEEEHHHCCCCHHHHHCCHHHHHHHHH
WSHCGSYHVTNWKDLGVPRITSLDDVKSLGRQVRESGYHALKTNLMMFDRPEPYMYRPGF
HHHCCCCCCCCCHHCCCCCCCCHHHHHHHHHHHHHCCCHHHHHCEEEEECCCCCEECCCC
AGGSGDPDRNPLRSAISAAVDQMTAFREGAGPDIGLKLDVNFNFRPEGYIRLAHALEPVD
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCHHEEEEHHCCCCC
LDWLEIDNFDAKAVAQVRRASRIPIASCETLSGRRQLRPYLEEQAVDVVIIDVPWNGIYE
CCEEEECCCCHHHHHHHHHHCCCCCCCCHHHCCHHHHHHHHHHCCCEEEEEECCCHHHHH
AMRMAALADSFEVNVATHNFCGPIATLISAHFCAAVPNFRVMEMDVVQVPWTNDLITNPP
HHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCCCC
TIERGYMRLPDGPGWGADVNEEALRAHPPVAAKH
CCCCCCEECCCCCCCCCCCCHHHHHCCCCCCCCC
>Mature Secondary Structure
MKITAVETLYCNAGWRNLSFLKISTDEGLVGWAEFPENHINNVLSPLVRHMGQQILGEDP
CEEEEEEEEEECCCCCCEEEEEEECCCCCEEHHHCCHHHHHHHHHHHHHHHHHHHHCCCC
RRIHPVIDRLRRAAWGVPFGAVSRAIGAIENALVDIKAKAIGVPAYELIGGRMRDDIRMY
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHEEEHHHCCCCHHHHHCCHHHHHHHHH
WSHCGSYHVTNWKDLGVPRITSLDDVKSLGRQVRESGYHALKTNLMMFDRPEPYMYRPGF
HHHCCCCCCCCCHHCCCCCCCCHHHHHHHHHHHHHCCCHHHHHCEEEEECCCCCEECCCC
AGGSGDPDRNPLRSAISAAVDQMTAFREGAGPDIGLKLDVNFNFRPEGYIRLAHALEPVD
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCHHEEEEHHCCCCC
LDWLEIDNFDAKAVAQVRRASRIPIASCETLSGRRQLRPYLEEQAVDVVIIDVPWNGIYE
CCEEEECCCCHHHHHHHHHHCCCCCCCCHHHCCHHHHHHHHHHCCCEEEEEECCCHHHHH
AMRMAALADSFEVNVATHNFCGPIATLISAHFCAAVPNFRVMEMDVVQVPWTNDLITNPP
HHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCCCC
TIERGYMRLPDGPGWGADVNEEALRAHPPVAAKH
CCCCCCEECCCCCCCCCCCCHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA