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The map label for this gene is dppA [H]

Identifier: 110633355

GI number: 110633355

Start: 1098249

End: 1099877

Strand: Reverse

Name: dppA [H]

Synonym: Meso_1001

Alternate gene names: 110633355

Gene position: 1099877-1098249 (Counterclockwise)

Preceding gene: 110633356

Following gene: 110633354

Centisome position: 24.93

GC content: 61.82

Gene sequence:

>1629_bases
ATGTTTACGCTCAATCGACGGCGAGCGCTCGGCTTGCTTGGTGCCACCGCGGGCAGCATCGCCCTGCCACGTTTCGCGAT
CGGCCAGACGGCTCGCCCGTCCGTCACCATCGCGGTGCAAAAGATCACCAACAACAACACGCTCGACATTTGGTATGAGC
AGTCCAATGTCGGCGAGCGTGTATTCTTCCCCAACCTCTGGGAAGGGTTGATCCTGCGCGATTGGATGGGCAACCAGGGC
CCCGTTCCCGGGCTTGCCACAGAATGGCGGCGCATCGACGACAAGACGCTCGAGCTCACGCTGCGCCAGGGCGTGAAGTT
CCACAATGGGGACGAATTGACCGCCGAGGATGTGGTGTTCAGTTTCTCGGCAGAGCGCGTCTTTGGCGACACGCAGCCCG
CTGGCGGCAGAACCATCTTCGAGACCGATCACAAACCAACCACGGTCAAAGAGCTGCCCGCGAGCGTGCCGGGCATCGGC
CGCCGTCTGTGGCCGGCTCTGGCCGGCGTCGAGGCGGTGGACAAATACACGGTGCGTTTCCACAATGCCACGCCGGATGT
GACGCTCGAAGGGCGCCTCTATTCCCACGGCAGCCAGATCGCCAACCGTCGTGCCTGGGATGAGGCTTCCTCCTACAACG
ACTGGGCGCGCAAGCCCATCACCACTGGCCCCTATATGGTCGGCGAATACCGGCCCGACGTTTCGCTGACGCTGGTTGCC
TTCGACGACTACTGGGGCGGGCGGCCGCCGCTGGAGCAGATCCGCTTCGTCGAGGTGCCGGAAGTATCCTCGCGCGTGAA
CGGCCTCTTGTCGGGCGAATATGATTTCGCCTGCGACCTGCCGCCGGATCAGATCGCCGCGGTGCAATCCGCTCCGGGTT
TCGAGGTCCAGAACTCCACGATCTGGAATCACCGCATTTCCGTCTTCAACACGCAGATCCCGATACTGGCCGATCCGCTT
GTGCGCCGCGCCATGACGCATTCGATCGACCGTCAGGCCATCGTCGATTCGCTCTGGGGCGGCCAGACGGTCATCCCGGC
CGGGCTGCAGTTCGAATCATTCGGCGACATGTTTGTACAGGGCTGGACTGTTCCGGAATTCAATCCTGAACTGGCGCGCG
ATCTGTTGCGGCAGGCGAACTACAAGGGCGACCCGATCCCTTATCGCCTGCTGAACAACTATTATACGAACCAGACACCC
ACGGCGCAGATCCTGGTCGAGATGTGGAAGCAGGTGGGCCTCAATGTCGAGATCGAGATGAAGGAGAACTGGGCTCAGAT
CCATGAGCCGGCCGGGGTGAAGGGTGTACGCGACTGGTCGGCGTCCAACACCATCAACGACCCGATCACCCCGATGGTGG
TGCAGTTCGGCCCCAATGGCGAGGTCCAGCAGAAGCAGGACTGGACCAACGCCGAGGTGAACGAGCTTTCCGTCGTGATG
GAAACCTCGACCGACAAGGCAAAGCGCAAGCAGGCTTTCGCCCGCATGCTGGAAATCTGCGAGCGCGAGGACCCCGCCTA
TACGGTTCTGCACCAGAACGCCGTTTTCACCGGCATGAAGTCTTCCCTGAAGTGGAAGGCGGCTCCCGCCTTCGCAATGG
ACTTCCGCAGTTCCAACTGGACGAGCTGA

Upstream 100 bases:

>100_bases
ATAGATATTTCATATGGATTTTATGAGCGTGACACACTCGGAACCCTAATGTGCGGCGCATGTGGAGTTGAATTATCTCC
GCCATTGAAAGGAGTTCTGG

Downstream 100 bases:

>100_bases
ACGCCACAGGCAGGCTCCGGCGCTTCGGCCGCCGGAGCCAAGCTCTTTTCCAATAGCGTCCATGGGCGTCGCTCGCGATG
GGCCTGCAAACCGCGGAAGA

Product: twin-arginine translocation pathway signal

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Dipeptide-binding protein; DBP [H]

Number of amino acids: Translated: 542; Mature: 542

Protein sequence:

>542_residues
MFTLNRRRALGLLGATAGSIALPRFAIGQTARPSVTIAVQKITNNNTLDIWYEQSNVGERVFFPNLWEGLILRDWMGNQG
PVPGLATEWRRIDDKTLELTLRQGVKFHNGDELTAEDVVFSFSAERVFGDTQPAGGRTIFETDHKPTTVKELPASVPGIG
RRLWPALAGVEAVDKYTVRFHNATPDVTLEGRLYSHGSQIANRRAWDEASSYNDWARKPITTGPYMVGEYRPDVSLTLVA
FDDYWGGRPPLEQIRFVEVPEVSSRVNGLLSGEYDFACDLPPDQIAAVQSAPGFEVQNSTIWNHRISVFNTQIPILADPL
VRRAMTHSIDRQAIVDSLWGGQTVIPAGLQFESFGDMFVQGWTVPEFNPELARDLLRQANYKGDPIPYRLLNNYYTNQTP
TAQILVEMWKQVGLNVEIEMKENWAQIHEPAGVKGVRDWSASNTINDPITPMVVQFGPNGEVQQKQDWTNAEVNELSVVM
ETSTDKAKRKQAFARMLEICEREDPAYTVLHQNAVFTGMKSSLKWKAAPAFAMDFRSSNWTS

Sequences:

>Translated_542_residues
MFTLNRRRALGLLGATAGSIALPRFAIGQTARPSVTIAVQKITNNNTLDIWYEQSNVGERVFFPNLWEGLILRDWMGNQG
PVPGLATEWRRIDDKTLELTLRQGVKFHNGDELTAEDVVFSFSAERVFGDTQPAGGRTIFETDHKPTTVKELPASVPGIG
RRLWPALAGVEAVDKYTVRFHNATPDVTLEGRLYSHGSQIANRRAWDEASSYNDWARKPITTGPYMVGEYRPDVSLTLVA
FDDYWGGRPPLEQIRFVEVPEVSSRVNGLLSGEYDFACDLPPDQIAAVQSAPGFEVQNSTIWNHRISVFNTQIPILADPL
VRRAMTHSIDRQAIVDSLWGGQTVIPAGLQFESFGDMFVQGWTVPEFNPELARDLLRQANYKGDPIPYRLLNNYYTNQTP
TAQILVEMWKQVGLNVEIEMKENWAQIHEPAGVKGVRDWSASNTINDPITPMVVQFGPNGEVQQKQDWTNAEVNELSVVM
ETSTDKAKRKQAFARMLEICEREDPAYTVLHQNAVFTGMKSSLKWKAAPAFAMDFRSSNWTS
>Mature_542_residues
MFTLNRRRALGLLGATAGSIALPRFAIGQTARPSVTIAVQKITNNNTLDIWYEQSNVGERVFFPNLWEGLILRDWMGNQG
PVPGLATEWRRIDDKTLELTLRQGVKFHNGDELTAEDVVFSFSAERVFGDTQPAGGRTIFETDHKPTTVKELPASVPGIG
RRLWPALAGVEAVDKYTVRFHNATPDVTLEGRLYSHGSQIANRRAWDEASSYNDWARKPITTGPYMVGEYRPDVSLTLVA
FDDYWGGRPPLEQIRFVEVPEVSSRVNGLLSGEYDFACDLPPDQIAAVQSAPGFEVQNSTIWNHRISVFNTQIPILADPL
VRRAMTHSIDRQAIVDSLWGGQTVIPAGLQFESFGDMFVQGWTVPEFNPELARDLLRQANYKGDPIPYRLLNNYYTNQTP
TAQILVEMWKQVGLNVEIEMKENWAQIHEPAGVKGVRDWSASNTINDPITPMVVQFGPNGEVQQKQDWTNAEVNELSVVM
ETSTDKAKRKQAFARMLEICEREDPAYTVLHQNAVFTGMKSSLKWKAAPAFAMDFRSSNWTS

Specific function: Dipeptide-binding protein of a transport system that can be subject to osmotic shock. DppA is also required for peptide chemotaxis [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=472, Percent_Identity=23.9406779661017, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1787551, Length=311, Percent_Identity=25.08038585209, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1787052, Length=511, Percent_Identity=23.4833659491194, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1787495, Length=442, Percent_Identity=24.8868778280543, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 60879; Mature: 60879

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTLNRRRALGLLGATAGSIALPRFAIGQTARPSVTIAVQKITNNNTLDIWYEQSNVGER
CCCCCCHHHHEEEECCCCCCCCCCHHCCCCCCCCEEEEEEEECCCCEEEEEEECCCCCCE
VFFPNLWEGLILRDWMGNQGPVPGLATEWRRIDDKTLELTLRQGVKFHNGDELTAEDVVF
EECCCHHHHHHHHHHCCCCCCCCCHHHHHHHCCCHHEEEEHHHCCEECCCCCCCHHHEEE
SFSAERVFGDTQPAGGRTIFETDHKPTTVKELPASVPGIGRRLWPALAGVEAVDKYTVRF
EEEHHHHCCCCCCCCCCEEEECCCCCCHHHHCCCCCCCCHHHHHHHHHCHHHHCEEEEEE
HNATPDVTLEGRLYSHGSQIANRRAWDEASSYNDWARKPITTGPYMVGEYRPDVSLTLVA
ECCCCCEEECCEEECCHHHHHHHHCCCCCCCCCHHHCCCCCCCCEEEECCCCCCEEEEEE
FDDYWGGRPPLEQIRFVEVPEVSSRVNGLLSGEYDFACDLPPDQIAAVQSAPGFEVQNST
EECCCCCCCCHHHCEEEECCCHHHHHCCEECCCCCEEECCCHHHHHHHCCCCCCEECCCE
IWNHRISVFNTQIPILADPLVRRAMTHSIDRQAIVDSLWGGQTVIPAGLQFESFGDMFVQ
EEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCEECCCCCCEEE
GWTVPEFNPELARDLLRQANYKGDPIPYRLLNNYYTNQTPTAQILVEMWKQVGLNVEIEM
CCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHCCCEEEEE
KENWAQIHEPAGVKGVRDWSASNTINDPITPMVVQFGPNGEVQQKQDWTNAEVNELSVVM
CCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCEEEEEE
ETSTDKAKRKQAFARMLEICEREDPAYTVLHQNAVFTGMKSSLKWKAAPAFAMDFRSSNW
ECCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHCCHHCCEECCCCCEEEECCCCCC
TS
CC
>Mature Secondary Structure
MFTLNRRRALGLLGATAGSIALPRFAIGQTARPSVTIAVQKITNNNTLDIWYEQSNVGER
CCCCCCHHHHEEEECCCCCCCCCCHHCCCCCCCCEEEEEEEECCCCEEEEEEECCCCCCE
VFFPNLWEGLILRDWMGNQGPVPGLATEWRRIDDKTLELTLRQGVKFHNGDELTAEDVVF
EECCCHHHHHHHHHHCCCCCCCCCHHHHHHHCCCHHEEEEHHHCCEECCCCCCCHHHEEE
SFSAERVFGDTQPAGGRTIFETDHKPTTVKELPASVPGIGRRLWPALAGVEAVDKYTVRF
EEEHHHHCCCCCCCCCCEEEECCCCCCHHHHCCCCCCCCHHHHHHHHHCHHHHCEEEEEE
HNATPDVTLEGRLYSHGSQIANRRAWDEASSYNDWARKPITTGPYMVGEYRPDVSLTLVA
ECCCCCEEECCEEECCHHHHHHHHCCCCCCCCCHHHCCCCCCCCEEEECCCCCCEEEEEE
FDDYWGGRPPLEQIRFVEVPEVSSRVNGLLSGEYDFACDLPPDQIAAVQSAPGFEVQNST
EECCCCCCCCHHHCEEEECCCHHHHHCCEECCCCCEEECCCHHHHHHHCCCCCCEECCCE
IWNHRISVFNTQIPILADPLVRRAMTHSIDRQAIVDSLWGGQTVIPAGLQFESFGDMFVQ
EEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCEECCCCCCEEE
GWTVPEFNPELARDLLRQANYKGDPIPYRLLNNYYTNQTPTAQILVEMWKQVGLNVEIEM
CCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHCCCEEEEE
KENWAQIHEPAGVKGVRDWSASNTINDPITPMVVQFGPNGEVQQKQDWTNAEVNELSVVM
CCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCEEEEEE
ETSTDKAKRKQAFARMLEICEREDPAYTVLHQNAVFTGMKSSLKWKAAPAFAMDFRSSNW
ECCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHCCHHCCEECCCCCEEEECCCCCC
TS
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1702779; 1956284; 7536291; 8041620; 9278503; 9298646; 9600841; 8563629; 8527431 [H]