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The map label for this gene is ptrB [H]

Identifier: 110633219

GI number: 110633219

Start: 956538

End: 958640

Strand: Reverse

Name: ptrB [H]

Synonym: Meso_0862

Alternate gene names: 110633219

Gene position: 958640-956538 (Counterclockwise)

Preceding gene: 110633220

Following gene: 110633217

Centisome position: 21.73

GC content: 63.29

Gene sequence:

>2103_bases
ATGTCCCCCCGCTCCCCGTTCCCTGCCCTGCCCGCGCCGAAAGCCGACAAGCGGCCTGTCACCGACACCCGGCACGGCTT
CACCCGTACTGACGAGTACGGCTGGCTGAGGGCCGGGAACTGGCAGGAGGTGCTCAGGAATCCGGCGGCGCTCGCGGACG
ATATCCGTGCGCATCTGGAGGCCGAGAACGCCTATCACGAAGCCATGATGGAAGACACGAAGGAGCTGCAGAAGCTCCTT
TTTGCCGAGATGAAGGGGCGCATCAAGGAAGACGAAAGCTCCGTCCCGATGAAGGATGGGCCCTTCGCTTACGGCAGCGC
CTATCGCAAAGGCGGTGAGCACCCGCGCTTCTTCCGCACGCCGCGGGAAGGCGGCGCGGAGGATGTGCTGCTCGACGGCG
ACCGGGAGGCGGAAGGCAAGAGCTATTTCCATATCGGCGGCGTCGGGCATTCCCCCGACCACCGCTATATGTTGTGGAGC
ATCGACGACAAGGGCTCGGAGTTCTTCACGCTGCGCGTGCGCGATCTTGAGACCAAGCGCGACTTGGCCGACCACGTGGA
GGGCACTAATGGCTCGGGCACGTTCACGGCCGACGCCCGCGGCTTCTATTACACGCGGCTCGACGACAACCACCGGCCAT
CAAAGGTTTTCTATCATGCGATAGGCGCGGATTCCGCCCAAGACCGGCTGGTCTATGAGGAGGCCGACCCCGGCTTTTTC
ATGAATGTGTTCGGCAGCCGGCTCGATGACTTCATCTTCATCTCAATCCACGACCATGAGACAAGCGAGTATCGCATCCT
TCCCGCCAATGAACCTCATGCCGAGCCGCGCATCGTGGCGCCGCGCGAGCCTGGGATCCGCTACGATATCGAGCCCGCGG
GCGAAGAGTTCTTCATCCTGACCAACCGCGACGGCGCGAAGGACTTCAAGATCATGACAGCGCCGGCGGCGGACCCCTCG
CCCGCCAACTGGCGCGAGCTGGTGCCGCACGAGCCTGGCCGGCTCATAATGTCCTTCCTCGCCTTCAAGGACTACCTCGT
GCGTCTTGAGCGCAAGGATGGGCTGCCGCGCATCGTCGTTCGCGAGCGCGCCAGCGGCGAAGAGCATGTGATCGCCTTCG
CGGAGGAGGCCTACGCGCTCGCCCTTTACGGTGCCTACGAGTACGACACGGATGTCTTCCGCTTCTCCTATTCTTCGATG
ACCACGCCCGCGCAGGAGTTCGATTACGACATGCGCACGCGCGAGCGCGTCCTCCTGAAGACGCAGGAGGTGCCTTCAGG
CCATAACCCGGAAGACTATGTGACGCGCCGATTGATGGCGACAGCACCCGACGGCGAGCAGGTGCCGATCTCGCTCGTCC
ACCGCCGCGATCTGCCGCTCGACGGTTCGGCGCCCTGCCTTCTTTACGGCTATGGCGCCTATGGCATCACCATCAGCGCC
TCCTTCCGCACAAATCCGCTATCGCTGGTCGACCGTGGCTTCGTCTATGCCATCGCCCATATCCGCGGCGGCAAGGACAA
AGGTTTTGCCTGGTATGAGGACGGCAAGCGGGAGAAGAAGGTGCATACCTTCACCGACTTCATCGCCTGTGCCCGGCACC
TCGTGGCGCAGGGCTATACGAGCCACGACCGGCTCGTCGCCGAAGGCGGCTCGGCGGGTGGCATGCTGATCGGCGCAGTC
GCAAATATGGCGCCGAAGGATTTCCGCGGCCTGGTGGCGGCGGTCCCGTTTGTCGACGTGCTCAACACGATGCTGGACGA
AACGCTGCCGCTCACCCCGCCCGAATGGCCGGAATGGGGAAACCCCGTTGCGAGCAAGCAGGATTACGAAACCATCGCGT
CCTATTCCCCTTACGATAATGTACGCGCGCAGCCCTATCCGGCCATCCTGGCGCTTGCCGGGCTGACGGACCCGCGCGTG
ACCTATTGGGAGCCGGCGAAATGGGTGGCGCGCCTGCGCGATTACAACACGAGCGAAAATCCCATCCTGCTCAAGGTCAA
TATGGAGGCCGGACATGCCGGAGCCTCCGGCCGCTTCTCACGCCTGGAAGAGACGGCGCTTAGCTATGCGTTCATGATGA
AGGCGGTGGGGATGGAGGAATAA

Upstream 100 bases:

>100_bases
CGAAAGGAAGTTATCGTCCGCAGCTAGCCATGATCCCTCACTAGCCCTAAAACCGCGCCAGCCAAGGCCGCTTTATTTCA
GCACCTCAGGAGTTTTCTCC

Downstream 100 bases:

>100_bases
GGGAGTAAGGCAGTAGGGCAGTAACGCAGCCGGATTATCTTTCGCCTATTGGAACGCCGCAGCGTTGCAATGTTCAGGCA
TGGATCCTCGGGTCAAGCCC

Product: oligopeptidase B

Products: NA

Alternate protein names: Oligopeptidase B; Protease II [H]

Number of amino acids: Translated: 700; Mature: 699

Protein sequence:

>700_residues
MSPRSPFPALPAPKADKRPVTDTRHGFTRTDEYGWLRAGNWQEVLRNPAALADDIRAHLEAENAYHEAMMEDTKELQKLL
FAEMKGRIKEDESSVPMKDGPFAYGSAYRKGGEHPRFFRTPREGGAEDVLLDGDREAEGKSYFHIGGVGHSPDHRYMLWS
IDDKGSEFFTLRVRDLETKRDLADHVEGTNGSGTFTADARGFYYTRLDDNHRPSKVFYHAIGADSAQDRLVYEEADPGFF
MNVFGSRLDDFIFISIHDHETSEYRILPANEPHAEPRIVAPREPGIRYDIEPAGEEFFILTNRDGAKDFKIMTAPAADPS
PANWRELVPHEPGRLIMSFLAFKDYLVRLERKDGLPRIVVRERASGEEHVIAFAEEAYALALYGAYEYDTDVFRFSYSSM
TTPAQEFDYDMRTRERVLLKTQEVPSGHNPEDYVTRRLMATAPDGEQVPISLVHRRDLPLDGSAPCLLYGYGAYGITISA
SFRTNPLSLVDRGFVYAIAHIRGGKDKGFAWYEDGKREKKVHTFTDFIACARHLVAQGYTSHDRLVAEGGSAGGMLIGAV
ANMAPKDFRGLVAAVPFVDVLNTMLDETLPLTPPEWPEWGNPVASKQDYETIASYSPYDNVRAQPYPAILALAGLTDPRV
TYWEPAKWVARLRDYNTSENPILLKVNMEAGHAGASGRFSRLEETALSYAFMMKAVGMEE

Sequences:

>Translated_700_residues
MSPRSPFPALPAPKADKRPVTDTRHGFTRTDEYGWLRAGNWQEVLRNPAALADDIRAHLEAENAYHEAMMEDTKELQKLL
FAEMKGRIKEDESSVPMKDGPFAYGSAYRKGGEHPRFFRTPREGGAEDVLLDGDREAEGKSYFHIGGVGHSPDHRYMLWS
IDDKGSEFFTLRVRDLETKRDLADHVEGTNGSGTFTADARGFYYTRLDDNHRPSKVFYHAIGADSAQDRLVYEEADPGFF
MNVFGSRLDDFIFISIHDHETSEYRILPANEPHAEPRIVAPREPGIRYDIEPAGEEFFILTNRDGAKDFKIMTAPAADPS
PANWRELVPHEPGRLIMSFLAFKDYLVRLERKDGLPRIVVRERASGEEHVIAFAEEAYALALYGAYEYDTDVFRFSYSSM
TTPAQEFDYDMRTRERVLLKTQEVPSGHNPEDYVTRRLMATAPDGEQVPISLVHRRDLPLDGSAPCLLYGYGAYGITISA
SFRTNPLSLVDRGFVYAIAHIRGGKDKGFAWYEDGKREKKVHTFTDFIACARHLVAQGYTSHDRLVAEGGSAGGMLIGAV
ANMAPKDFRGLVAAVPFVDVLNTMLDETLPLTPPEWPEWGNPVASKQDYETIASYSPYDNVRAQPYPAILALAGLTDPRV
TYWEPAKWVARLRDYNTSENPILLKVNMEAGHAGASGRFSRLEETALSYAFMMKAVGMEE
>Mature_699_residues
SPRSPFPALPAPKADKRPVTDTRHGFTRTDEYGWLRAGNWQEVLRNPAALADDIRAHLEAENAYHEAMMEDTKELQKLLF
AEMKGRIKEDESSVPMKDGPFAYGSAYRKGGEHPRFFRTPREGGAEDVLLDGDREAEGKSYFHIGGVGHSPDHRYMLWSI
DDKGSEFFTLRVRDLETKRDLADHVEGTNGSGTFTADARGFYYTRLDDNHRPSKVFYHAIGADSAQDRLVYEEADPGFFM
NVFGSRLDDFIFISIHDHETSEYRILPANEPHAEPRIVAPREPGIRYDIEPAGEEFFILTNRDGAKDFKIMTAPAADPSP
ANWRELVPHEPGRLIMSFLAFKDYLVRLERKDGLPRIVVRERASGEEHVIAFAEEAYALALYGAYEYDTDVFRFSYSSMT
TPAQEFDYDMRTRERVLLKTQEVPSGHNPEDYVTRRLMATAPDGEQVPISLVHRRDLPLDGSAPCLLYGYGAYGITISAS
FRTNPLSLVDRGFVYAIAHIRGGKDKGFAWYEDGKREKKVHTFTDFIACARHLVAQGYTSHDRLVAEGGSAGGMLIGAVA
NMAPKDFRGLVAAVPFVDVLNTMLDETLPLTPPEWPEWGNPVASKQDYETIASYSPYDNVRAQPYPAILALAGLTDPRVT
YWEPAKWVARLRDYNTSENPILLKVNMEAGHAGASGRFSRLEETALSYAFMMKAVGMEE

Specific function: Cleaves peptide bonds on the C-terminal side of lysyl and argininyl residues [H]

COG id: COG1770

COG function: function code E; Protease II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S9A family [H]

Homologues:

Organism=Homo sapiens, GI41349456, Length=730, Percent_Identity=25.0684931506849, Blast_Score=200, Evalue=3e-51,
Organism=Homo sapiens, GI284172420, Length=568, Percent_Identity=28.169014084507, Blast_Score=200, Evalue=4e-51,
Organism=Homo sapiens, GI284172413, Length=568, Percent_Identity=28.169014084507, Blast_Score=200, Evalue=4e-51,
Organism=Homo sapiens, GI70778815, Length=568, Percent_Identity=28.169014084507, Blast_Score=200, Evalue=4e-51,
Organism=Homo sapiens, GI284172438, Length=442, Percent_Identity=30.5429864253394, Blast_Score=200, Evalue=5e-51,
Organism=Homo sapiens, GI284172431, Length=442, Percent_Identity=30.5429864253394, Blast_Score=200, Evalue=5e-51,
Organism=Homo sapiens, GI108860686, Length=234, Percent_Identity=37.6068376068376, Blast_Score=151, Evalue=3e-36,
Organism=Homo sapiens, GI108860692, Length=211, Percent_Identity=37.914691943128, Blast_Score=145, Evalue=2e-34,
Organism=Escherichia coli, GI1788150, Length=685, Percent_Identity=38.978102189781, Blast_Score=448, Evalue=1e-127,
Organism=Drosophila melanogaster, GI24583414, Length=732, Percent_Identity=25, Blast_Score=194, Evalue=1e-49,
Organism=Drosophila melanogaster, GI221510989, Length=727, Percent_Identity=24.2090784044017, Blast_Score=176, Evalue=5e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002471
- InterPro:   IPR001375
- InterPro:   IPR002470
- InterPro:   IPR004106 [H]

Pfam domain/function: PF00326 Peptidase_S9; PF02897 Peptidase_S9_N [H]

EC number: =3.4.21.83 [H]

Molecular weight: Translated: 78747; Mature: 78616

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPRSPFPALPAPKADKRPVTDTRHGFTRTDEYGWLRAGNWQEVLRNPAALADDIRAHLE
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCHHHHHCCCHHHHHHHHHHHH
AENAYHEAMMEDTKELQKLLFAEMKGRIKEDESSVPMKDGPFAYGSAYRKGGEHPRFFRT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCEECC
PREGGAEDVLLDGDREAEGKSYFHIGGVGHSPDHRYMLWSIDDKGSEFFTLRVRDLETKR
CCCCCCCCEEECCCCCCCCCCEEEECCCCCCCCCCEEEEEECCCCCEEEEEEEECCCHHH
DLADHVEGTNGSGTFTADARGFYYTRLDDNHRPSKVFYHAIGADSAQDRLVYEEADPGFF
HHHHHCCCCCCCEEEEECCCCEEEEECCCCCCCCEEEEEEECCCCCCCCEEEEECCCCEE
MNVFGSRLDDFIFISIHDHETSEYRILPANEPHAEPRIVAPREPGIRYDIEPAGEEFFIL
HHHHHCCCCCEEEEEEECCCCCCEEEECCCCCCCCCEEECCCCCCCEEECCCCCCEEEEE
TNRDGAKDFKIMTAPAADPSPANWRELVPHEPGRLIMSFLAFKDYLVRLERKDGLPRIVV
ECCCCCCCEEEEECCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEE
RERASGEEHVIAFAEEAYALALYGAYEYDTDVFRFSYSSMTTPAQEFDYDMRTRERVLLK
ECCCCCCCEEEEEECCCEEEEEEECEECCCCEEEEECCCCCCCHHHHCCCHHHHHHHEEE
TQEVPSGHNPEDYVTRRLMATAPDGEQVPISLVHRRDLPLDGSAPCLLYGYGAYGITISA
EECCCCCCCCHHHHHHHHHEECCCCCCCCEEEEECCCCCCCCCCCEEEEEECEEEEEEEE
SFRTNPLSLVDRGFVYAIAHIRGGKDKGFAWYEDGKREKKVHTFTDFIACARHLVAQGYT
ECCCCCHHHHHCCEEEEEEEECCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCC
SHDRLVAEGGSAGGMLIGAVANMAPKDFRGLVAAVPFVDVLNTMLDETLPLTPPEWPEWG
CCCEEEECCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
NPVASKQDYETIASYSPYDNVRAQPYPAILALAGLTDPRVTYWEPAKWVARLRDYNTSEN
CCCCCCCCHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCEEECHHHHHHHHHCCCCCCC
PILLKVNMEAGHAGASGRFSRLEETALSYAFMMKAVGMEE
CEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SPRSPFPALPAPKADKRPVTDTRHGFTRTDEYGWLRAGNWQEVLRNPAALADDIRAHLE
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCHHHHHCCCHHHHHHHHHHHH
AENAYHEAMMEDTKELQKLLFAEMKGRIKEDESSVPMKDGPFAYGSAYRKGGEHPRFFRT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCEECC
PREGGAEDVLLDGDREAEGKSYFHIGGVGHSPDHRYMLWSIDDKGSEFFTLRVRDLETKR
CCCCCCCCEEECCCCCCCCCCEEEECCCCCCCCCCEEEEEECCCCCEEEEEEEECCCHHH
DLADHVEGTNGSGTFTADARGFYYTRLDDNHRPSKVFYHAIGADSAQDRLVYEEADPGFF
HHHHHCCCCCCCEEEEECCCCEEEEECCCCCCCCEEEEEEECCCCCCCCEEEEECCCCEE
MNVFGSRLDDFIFISIHDHETSEYRILPANEPHAEPRIVAPREPGIRYDIEPAGEEFFIL
HHHHHCCCCCEEEEEEECCCCCCEEEECCCCCCCCCEEECCCCCCCEEECCCCCCEEEEE
TNRDGAKDFKIMTAPAADPSPANWRELVPHEPGRLIMSFLAFKDYLVRLERKDGLPRIVV
ECCCCCCCEEEEECCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEE
RERASGEEHVIAFAEEAYALALYGAYEYDTDVFRFSYSSMTTPAQEFDYDMRTRERVLLK
ECCCCCCCEEEEEECCCEEEEEEECEECCCCEEEEECCCCCCCHHHHCCCHHHHHHHEEE
TQEVPSGHNPEDYVTRRLMATAPDGEQVPISLVHRRDLPLDGSAPCLLYGYGAYGITISA
EECCCCCCCCHHHHHHHHHEECCCCCCCCEEEEECCCCCCCCCCCEEEEEECEEEEEEEE
SFRTNPLSLVDRGFVYAIAHIRGGKDKGFAWYEDGKREKKVHTFTDFIACARHLVAQGYT
ECCCCCHHHHHCCEEEEEEEECCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCC
SHDRLVAEGGSAGGMLIGAVANMAPKDFRGLVAAVPFVDVLNTMLDETLPLTPPEWPEWG
CCCEEEECCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
NPVASKQDYETIASYSPYDNVRAQPYPAILALAGLTDPRVTYWEPAKWVARLRDYNTSEN
CCCCCCCCHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCEEECHHHHHHHHHCCCCCCC
PILLKVNMEAGHAGASGRFSRLEETALSYAFMMKAVGMEE
CEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1769955; 9097040; 9278503 [H]