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The map label for this gene is cysQ [H]

Identifier: 110633192

GI number: 110633192

Start: 926900

End: 927724

Strand: Direct

Name: cysQ [H]

Synonym: Meso_0835

Alternate gene names: 110633192

Gene position: 926900-927724 (Clockwise)

Preceding gene: 110633191

Following gene: 110633195

Centisome position: 21.01

GC content: 65.94

Gene sequence:

>825_bases
TTGCTGACCTCCGCCCTTCCGTCGATGGCTGGCGAGACAGCCCTTCTGGCGCTCTTCGAGGAGCTGGCGCTTGCGGCCGG
CCGTCAGGTCATGGCGCATTATGAAGCCGGCGTGCAGATCGAGCACAAATCCGATGCCTCCCCCGTGACGGAAGCCGATC
GTGCCGCCGAGCGCGTCATTCTCGCCGGGCTGCGTGCCACCGTGGCGGGGACGCCGTGCGTCTCTGAAGAGGAGGCCTCG
GGCGGCGTGCTGCCGGCCTGCGGCGACGAAGGATTTTTTCTGGTCGACCCGCTCGACGGCACCCGCGAATTCATTGGGCG
CAGGCCGGATTTCACGGTCAACATAGCCTATGTGAAGGATGGTGCTCCGGTGGTCGGCGTGGTCTATGCGCCGGCGCGCG
GGCTTCTCTATTCCGGCAGGCCCGGCGCGGCCTTCGAAGCCGAATGCCACAACGGCGCAATCACAAGCCGCCGCGGGATC
AATACCCGCCCGCGGCGCAATCCTCCAGCGATCGTGGCCAGCCGCTCCCATTCCACGCCGGAAACGGAAGCCTTCATCGC
CCGCTATCCCGGCGCGGAAACCGTCTCCGTCGGCTCGTCGCTGAAATTCTGCATGATTGCCTGCGGCCAGGCGGATCTTT
ATCCGCGTTACGGCCGCACCATGCAGTGGGATACGGCAGCCGGTGACGCGGTGCTGCGCGCCGCGGGTGGCAGCACGCTT
ACGCTTCAAGGCAAACCGCTTACCTATGGGCCGAAGGAAGGTGAGGGACTGGAGGCTTTCGCCAACCCGTTCTTCATAGC
CGAGGGGCGGGCGGCTCAAGATTAG

Upstream 100 bases:

>100_bases
ATGAGGCTCCCGAGAACCCGGATCTTCACCTGCACACCGTGGGCAGGGCACCCGAAGATATGGCGGACGAATTGGAAACC
TGGCTGCGGGAGCGCGGATA

Downstream 100 bases:

>100_bases
ACCGGTTGCACCGGTGCTCCGTCACGCCCCCCTCTGCCCTGCCGGCCATCTCCCCCACAAGGGGGGAGATCAGCATTCAT
GACGGTTTTCGCTGATCACC

Product: 3'(2'),5'-bisphosphate nucleotidase

Products: NA

Alternate protein names: 3'(2'),5-bisphosphonucleoside 3'(2')-phosphohydrolase; 3'-phosphoadenosine 5'-phosphate phosphatase; PAP phosphatase; DPNPase [H]

Number of amino acids: Translated: 274; Mature: 274

Protein sequence:

>274_residues
MLTSALPSMAGETALLALFEELALAAGRQVMAHYEAGVQIEHKSDASPVTEADRAAERVILAGLRATVAGTPCVSEEEAS
GGVLPACGDEGFFLVDPLDGTREFIGRRPDFTVNIAYVKDGAPVVGVVYAPARGLLYSGRPGAAFEAECHNGAITSRRGI
NTRPRRNPPAIVASRSHSTPETEAFIARYPGAETVSVGSSLKFCMIACGQADLYPRYGRTMQWDTAAGDAVLRAAGGSTL
TLQGKPLTYGPKEGEGLEAFANPFFIAEGRAAQD

Sequences:

>Translated_274_residues
MLTSALPSMAGETALLALFEELALAAGRQVMAHYEAGVQIEHKSDASPVTEADRAAERVILAGLRATVAGTPCVSEEEAS
GGVLPACGDEGFFLVDPLDGTREFIGRRPDFTVNIAYVKDGAPVVGVVYAPARGLLYSGRPGAAFEAECHNGAITSRRGI
NTRPRRNPPAIVASRSHSTPETEAFIARYPGAETVSVGSSLKFCMIACGQADLYPRYGRTMQWDTAAGDAVLRAAGGSTL
TLQGKPLTYGPKEGEGLEAFANPFFIAEGRAAQD
>Mature_274_residues
MLTSALPSMAGETALLALFEELALAAGRQVMAHYEAGVQIEHKSDASPVTEADRAAERVILAGLRATVAGTPCVSEEEAS
GGVLPACGDEGFFLVDPLDGTREFIGRRPDFTVNIAYVKDGAPVVGVVYAPARGLLYSGRPGAAFEAECHNGAITSRRGI
NTRPRRNPPAIVASRSHSTPETEAFIARYPGAETVSVGSSLKFCMIACGQADLYPRYGRTMQWDTAAGDAVLRAAGGSTL
TLQGKPLTYGPKEGEGLEAFANPFFIAEGRAAQD

Specific function: Converts 3'(2')-phosphoadenosine 5'-phosphate (PAP) to AMP. May also convert adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) [H]

COG id: COG1218

COG function: function code P; 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Homo sapiens, GI7657236, Length=239, Percent_Identity=28.0334728033473, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI221625487, Length=235, Percent_Identity=24.6808510638298, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI5031789, Length=235, Percent_Identity=25.531914893617, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1790659, Length=247, Percent_Identity=45.3441295546559, Blast_Score=184, Evalue=5e-48,
Organism=Escherichia coli, GI1788882, Length=226, Percent_Identity=28.3185840707965, Blast_Score=69, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71995897, Length=162, Percent_Identity=34.5679012345679, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71995905, Length=162, Percent_Identity=34.5679012345679, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI193202570, Length=216, Percent_Identity=25.462962962963, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI193202572, Length=210, Percent_Identity=27.6190476190476, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24641722, Length=201, Percent_Identity=29.8507462686567, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21357329, Length=237, Percent_Identity=26.1603375527426, Blast_Score=71, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006240
- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.7 [H]

Molecular weight: Translated: 28764; Mature: 28764

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS00630 IMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTSALPSMAGETALLALFEELALAAGRQVMAHYEAGVQIEHKSDASPVTEADRAAERVI
CCCCCCHHHCCHHHHHHHHHHHHHHHCHHHEEHHHCCEEEECCCCCCCCHHHHHHHHHHH
LAGLRATVAGTPCVSEEEASGGVLPACGDEGFFLVDPLDGTREFIGRRPDFTVNIAYVKD
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHCCCCCEEEEEEEEEC
GAPVVGVVYAPARGLLYSGRPGAAFEAECHNGAITSRRGINTRPRRNPPAIVASRSHSTP
CCCEEEEEECCCCCEEECCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCC
ETEAFIARYPGAETVSVGSSLKFCMIACGQADLYPRYGRTMQWDTAAGDAVLRAAGGSTL
CHHEEEEECCCCCEEECCCCCEEEEEECCCCCCCCCCCCEEEECCCCCCEEEEECCCCEE
TLQGKPLTYGPKEGEGLEAFANPFFIAEGRAAQD
EEECCCCCCCCCCCCCCHHHCCCEEEECCCCCCC
>Mature Secondary Structure
MLTSALPSMAGETALLALFEELALAAGRQVMAHYEAGVQIEHKSDASPVTEADRAAERVI
CCCCCCHHHCCHHHHHHHHHHHHHHHCHHHEEHHHCCEEEECCCCCCCCHHHHHHHHHHH
LAGLRATVAGTPCVSEEEASGGVLPACGDEGFFLVDPLDGTREFIGRRPDFTVNIAYVKD
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHCCCCCEEEEEEEEEC
GAPVVGVVYAPARGLLYSGRPGAAFEAECHNGAITSRRGINTRPRRNPPAIVASRSHSTP
CCCEEEEEECCCCCEEECCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCC
ETEAFIARYPGAETVSVGSSLKFCMIACGQADLYPRYGRTMQWDTAAGDAVLRAAGGSTL
CHHEEEEECCCCCEEECCCCCEEEEEECCCCCCCCCCCCEEEECCCCCCEEEEECCCCEE
TLQGKPLTYGPKEGEGLEAFANPFFIAEGRAAQD
EEECCCCCCCCCCCCCCHHHCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]