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The map label for this gene is ytxM [H]

Identifier: 110633177

GI number: 110633177

Start: 907940

End: 908788

Strand: Direct

Name: ytxM [H]

Synonym: Meso_0820

Alternate gene names: 110633177

Gene position: 907940-908788 (Clockwise)

Preceding gene: 110633176

Following gene: 110633178

Centisome position: 20.58

GC content: 68.2

Gene sequence:

>849_bases
ATGATGATTATGCGCCAGACCCTCACCAACGGCATAGAATGGCGGGAGCGCGCCGGCGGCGGCGACGTCCTCGTGTGCCT
GCACGGCATCGGGTCCACGGCCTCGACCTTCGACGGTCTGATCGGCTATCTGCCCGCCGACTTGCGCGTCATCTGCTGGA
ACGCTCCCGGTTACGGCGAAAGCGCGCCGCTTGCGGCCGATTGGCCGCTGGCCGCCGATTATGCCATGGCGCTGCTCTCG
CTTTGCGAGGCCCTGGAGCTCAAGCGGGTTCATATTCTTGGCCATTCGCTGGGCACGCTCATGGGCGCGGCCTTCGCCGC
CGGTCATCCAGAACGGGTCGCCAGTCTGACGCTCGCCGCCTGCGCCCAGGGCCGCGCCACCCCGCGCGGCGGCACGCTTT
CCGAAAAGGACGCGCAGCGCCTCGACGATCTTGAACGCGATGGGGCCGAAGCGTTCGCCGCGGCCAGGGCTCCGCGCCTG
ATCCATGCGCCGGAGCGCAATCCGGACCTCGTCGCCGCCGTGCGTCAGGACATGGCCAAGGTCACCATGCCCGGTTATGG
CCAGGCCGTGCGAATGCTCGCCTCGGGCGATCTCGCCGCCGATTGCAGACGGGTCCGCAGCCGTACTTCGGTCATCGTCG
GCACAGGGGACGTGGTGACGCCGCCGGACCAGTCCCGCGCCGCCTTTGACGCGCTCGATGAAGCTGTCCGCGGGGACTAC
GCTCTCGTGCCCCATGCCGGCCACGCCATTCACCGCCAGGCCCCCGCCGCCTTGGCTGCCACCATCGTTTCGACGATGAG
GAGTGCTCTGCCTTTGGCAGGCACGATACAATTGGGAGACGTCCGATGA

Upstream 100 bases:

>100_bases
CCAAGATCCCGCGCCCCGCTGGAAATAAGGCCGCGGGCTGACACCCGCCGGGGGGAGGGGCCGCAGGCCCCTCTCGCTTT
GAACACGGCTCTTGTTTTTC

Downstream 100 bases:

>100_bases
GTGAACCCATCCGCGTTGGTGCCCTGCGCGGCATCGTTATGCGCGCGCCGGGCATAACCGCCACCAGGGGCTTTTACGAG
AATAATTGGGGGTTGACCGT

Product: alpha/beta hydrolase fold

Products: 2-oxopent-4-enoate; succinate [C]

Alternate protein names: NA

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MMIMRQTLTNGIEWRERAGGGDVLVCLHGIGSTASTFDGLIGYLPADLRVICWNAPGYGESAPLAADWPLAADYAMALLS
LCEALELKRVHILGHSLGTLMGAAFAAGHPERVASLTLAACAQGRATPRGGTLSEKDAQRLDDLERDGAEAFAAARAPRL
IHAPERNPDLVAAVRQDMAKVTMPGYGQAVRMLASGDLAADCRRVRSRTSVIVGTGDVVTPPDQSRAAFDALDEAVRGDY
ALVPHAGHAIHRQAPAALAATIVSTMRSALPLAGTIQLGDVR

Sequences:

>Translated_282_residues
MMIMRQTLTNGIEWRERAGGGDVLVCLHGIGSTASTFDGLIGYLPADLRVICWNAPGYGESAPLAADWPLAADYAMALLS
LCEALELKRVHILGHSLGTLMGAAFAAGHPERVASLTLAACAQGRATPRGGTLSEKDAQRLDDLERDGAEAFAAARAPRL
IHAPERNPDLVAAVRQDMAKVTMPGYGQAVRMLASGDLAADCRRVRSRTSVIVGTGDVVTPPDQSRAAFDALDEAVRGDY
ALVPHAGHAIHRQAPAALAATIVSTMRSALPLAGTIQLGDVR
>Mature_282_residues
MMIMRQTLTNGIEWRERAGGGDVLVCLHGIGSTASTFDGLIGYLPADLRVICWNAPGYGESAPLAADWPLAADYAMALLS
LCEALELKRVHILGHSLGTLMGAAFAAGHPERVASLTLAACAQGRATPRGGTLSEKDAQRLDDLERDGAEAFAAARAPRL
IHAPERNPDLVAAVRQDMAKVTMPGYGQAVRMLASGDLAADCRRVRSRTSVIVGTGDVVTPPDQSRAAFDALDEAVRGDY
ALVPHAGHAIHRQAPAALAATIVSTMRSALPLAGTIQLGDVR

Specific function: 3-hydroxyphenylpropionate degradation. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lipase/esterase LIP3/BchO family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639
- InterPro:   IPR022485 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: 3.7.1.- [C]

Molecular weight: Translated: 29619; Mature: 29619

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: PS00120 LIPASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMIMRQTLTNGIEWRERAGGGDVLVCLHGIGSTASTFDGLIGYLPADLRVICWNAPGYGE
CCCHHHHHHCCHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHCCCCEEEEEECCCCCCC
SAPLAADWPLAADYAMALLSLCEALELKRVHILGHSLGTLMGAAFAAGHPERVASLTLAA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
CAQGRATPRGGTLSEKDAQRLDDLERDGAEAFAAARAPRLIHAPERNPDLVAAVRQDMAK
HHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHH
VTMPGYGQAVRMLASGDLAADCRRVRSRTSVIVGTGDVVTPPDQSRAAFDALDEAVRGDY
HCCCCHHHHHHHHHCCCHHHHHHHHHHHCEEEEECCCEECCCCCHHHHHHHHHHHHCCCE
ALVPHAGHAIHRQAPAALAATIVSTMRSALPLAGTIQLGDVR
EECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCC
>Mature Secondary Structure
MMIMRQTLTNGIEWRERAGGGDVLVCLHGIGSTASTFDGLIGYLPADLRVICWNAPGYGE
CCCHHHHHHCCHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHCCCCEEEEEECCCCCCC
SAPLAADWPLAADYAMALLSLCEALELKRVHILGHSLGTLMGAAFAAGHPERVASLTLAA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
CAQGRATPRGGTLSEKDAQRLDDLERDGAEAFAAARAPRLIHAPERNPDLVAAVRQDMAK
HHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHH
VTMPGYGQAVRMLASGDLAADCRRVRSRTSVIVGTGDVVTPPDQSRAAFDALDEAVRGDY
HCCCCHHHHHHHHHCCCHHHHHHHHHHHCEEEEECCCEECCCCCHHHHHHHHHHHHCCCE
ALVPHAGHAIHRQAPAALAATIVSTMRSALPLAGTIQLGDVR
EECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-hydroxy-6-ketononadienedicarboxylate; H2O [C]

Specific reaction: 2-hydroxy-6-ketononadienedicarboxylate + H2O = 2-oxopent-4-enoate + succinate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8566759; 9387221; 9384377 [H]