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The map label for this gene is cutS [H]

Identifier: 110632833

GI number: 110632833

Start: 521420

End: 521914

Strand: Reverse

Name: cutS [H]

Synonym: Meso_0472

Alternate gene names: 110632833

Gene position: 521914-521420 (Counterclockwise)

Preceding gene: 110632834

Following gene: 110632832

Centisome position: 11.83

GC content: 53.54

Gene sequence:

>495_bases
ATGAGAATCGCTATGAAGGTGAACGGTGTCGCCCGAGATGTCGAGATCGATGAACGCATGCTACTGGCGGAGGTCTTGCG
GGGACCTCTCGGATTGAAGGGAACGCGCATTGGATGCCTTACCGGCGATTGCGGGGCGTGCACTATTTTGTTCAACGGGG
AGCTTCGGAAATCCTGCCTGATGCTGGCACAGGCTGCTCGTGATGCAGATGTCCAGACGATCGAGCATTGCAGCACAGAG
ATTGACGTGGTTCGCGAGGCATTTGTCGAAGCCCATGGGTTCCAATGCGGATTTTGCACCTCTGGAATGATTCTAGTGGC
GGCTGAGCTATTGAATCGGGATCAGGAGGTGAGCGCAGCAGATATCCGCCAAGCGATAAGCGGCAATCTCTGTCGTTGCA
CGGGCTACGATAACATTGTGGTCTCTATCCAGAATGCATTGGCAAGGAATTCGGACCAGCGAAATAAAATGTCCCAAGAT
TCACCTGCCGGATAA

Upstream 100 bases:

>100_bases
ATCCGTGGAGCGATGCACTCGCGCCAGCAGCATATCGGCAACGCATCGTCAAATCGGTTGTCACGCGGGCTGTGAAGCAG
GCCCTAGCGGAGGCCACGGC

Downstream 100 bases:

>100_bases
ACTCTGGCTCAACGAAACAGAGTTTCGCTCTGTGCCGACCAGGTGCAATAATCAGCAAAGCGCCCTTCAGCCGTATGGGG
GATCTCAATCTCCGCATCGC

Product: (2Fe-2S)-binding

Products: NA

Alternate protein names: CO dehydrogenase subunit S; CO-DH S [H]

Number of amino acids: Translated: 164; Mature: 164

Protein sequence:

>164_residues
MRIAMKVNGVARDVEIDERMLLAEVLRGPLGLKGTRIGCLTGDCGACTILFNGELRKSCLMLAQAARDADVQTIEHCSTE
IDVVREAFVEAHGFQCGFCTSGMILVAAELLNRDQEVSAADIRQAISGNLCRCTGYDNIVVSIQNALARNSDQRNKMSQD
SPAG

Sequences:

>Translated_164_residues
MRIAMKVNGVARDVEIDERMLLAEVLRGPLGLKGTRIGCLTGDCGACTILFNGELRKSCLMLAQAARDADVQTIEHCSTE
IDVVREAFVEAHGFQCGFCTSGMILVAAELLNRDQEVSAADIRQAISGNLCRCTGYDNIVVSIQNALARNSDQRNKMSQD
SPAG
>Mature_164_residues
MRIAMKVNGVARDVEIDERMLLAEVLRGPLGLKGTRIGCLTGDCGACTILFNGELRKSCLMLAQAARDADVQTIEHCSTE
IDVVREAFVEAHGFQCGFCTSGMILVAAELLNRDQEVSAADIRQAISGNLCRCTGYDNIVVSIQNALARNSDQRNKMSQD
SPAG

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=137, Percent_Identity=36.4963503649635, Blast_Score=69, Evalue=2e-12,
Organism=Homo sapiens, GI71773480, Length=86, Percent_Identity=39.5348837209302, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1786480, Length=163, Percent_Identity=38.6503067484663, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1789232, Length=147, Percent_Identity=35.3741496598639, Blast_Score=97, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17540638, Length=147, Percent_Identity=40.1360544217687, Blast_Score=103, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17539860, Length=156, Percent_Identity=33.3333333333333, Blast_Score=85, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI32566215, Length=156, Percent_Identity=32.6923076923077, Blast_Score=82, Evalue=1e-16,
Organism=Drosophila melanogaster, GI17737937, Length=148, Percent_Identity=36.4864864864865, Blast_Score=89, Evalue=9e-19,
Organism=Drosophila melanogaster, GI24647197, Length=162, Percent_Identity=29.0123456790123, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24647195, Length=162, Percent_Identity=29.0123456790123, Blast_Score=74, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24647193, Length=158, Percent_Identity=27.2151898734177, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24647199, Length=156, Percent_Identity=26.2820512820513, Blast_Score=66, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 17694; Mature: 17694

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
9.1 %Cys+Met (Translated Protein)
5.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
9.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIAMKVNGVARDVEIDERMLLAEVLRGPLGLKGTRIGCLTGDCGACTILFNGELRKSCL
CEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCCEEEEEECCHHHHHHH
MLAQAARDADVQTIEHCSTEIDVVREAFVEAHGFQCGFCTSGMILVAAELLNRDQEVSAA
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCHHHHHHHHHCCCCCCCHH
DIRQAISGNLCRCTGYDNIVVSIQNALARNSDQRNKMSQDSPAG
HHHHHHCCCEEEECCCCCEEEHHHHHHHCCCCHHHCCCCCCCCC
>Mature Secondary Structure
MRIAMKVNGVARDVEIDERMLLAEVLRGPLGLKGTRIGCLTGDCGACTILFNGELRKSCL
CEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCCEEEEEECCHHHHHHH
MLAQAARDADVQTIEHCSTEIDVVREAFVEAHGFQCGFCTSGMILVAAELLNRDQEVSAA
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCHHHHHHHHHCCCCCCCHH
DIRQAISGNLCRCTGYDNIVVSIQNALARNSDQRNKMSQDSPAG
HHHHHHCCCEEEECCCCCEEEHHHHHHHCCCCHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10482497; 2818128; 10966817; 11076018 [H]