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The map label for this gene is rsmB [H]

Identifier: 110632825

GI number: 110632825

Start: 511411

End: 512694

Strand: Reverse

Name: rsmB [H]

Synonym: Meso_0464

Alternate gene names: 110632825

Gene position: 512694-511411 (Counterclockwise)

Preceding gene: 110632828

Following gene: 110632819

Centisome position: 11.62

GC content: 66.82

Gene sequence:

>1284_bases
ATGCGACTGGGCGGGCGGCTTGCTGCGGCCATCGAGATTCTCGAAGACATCGAAACACGACATCGCCCCGCGGCCGATGC
CATGCGGGACTGGGGTCTTTCACATCGGTTCGCTGGAGCCGGCGACCGAGCCGCAATCGGCAATTTCGTCTATGACGCGC
TGCGCCGCCGCCGCGCCGCTGCATGGATCTTCGATGCAGATTCGCCCAGGACGCTGGTGCTGGGCAGCTACCTCCTGGAA
AGCGGCGTTCTTCCCCAGGAACTCGGCAGGCTGATCGCCGACGACCGGTTCGCGCCCTCCATGCTTACGGAGGCTGAACT
GGCGGCGCTTCAAGCCCGGCTCTCGGAAGAGCTGCCTGCGCCCGCCCGCGCCAATGCCCCGGAATGGTGCGAGCCGTTGA
TGGAGGAGGCCTTCGGCGCCGCATGGGTGGATGAAGGGGCTGCCCTCGCCTCGCGCCCGCCCCTCGACATGCGCGTCAAC
CGGCTGAAAGCATCGCGCGAGAAGGTGCTGGCGAGTCTCGCGCGTGCCGGCGCCAAGCCCGCCCGCATCGCGCCCAGCGG
CCTGCGCATCGCGCCCATCTCCGGCGATGGCCGTCATCCCAATATTCAGGCCGAACCCGCCTTTCAGAAGGGCTGGTTCG
AGGTGCAGGATGAAGGCTCCCAAATCGTGGCTGAGCTTGCAGGGCCTGCTCAGGGCAGCCAGGTGCTCGATTTCTGCGCC
GGTGCGGGCGGCAAGACGCTCGCCTTCTCGGCCATGATGGATAATCGCGGCCAGATTTATGCCTTCGATGCCGACAAGCA
GCGTCTGGCCCCCATTTTCGACCGACTCAAGCGGGCGGGCTGCCGCAATGTGCAGGTGATTGCGGACGAGGGGCAATTGA
CGCGCCTCGAAGGCCAGATGGATCTCGTCGTGGTGGACGCGCCCTGCACAGGCTCCGGCACCTGGCGCCGGCGTCCCGAT
GCCAAGTGGCGCCTGACCGCACAGCAGCTCGAGGCGCGCCGGGCCGAGCAGGCCACAATTCTTGATGCTGCCAGCCGCTA
TGTGAAGCCCGGCGGCCGGCTCGCCTACATCACCTGCTCGATCTTCCAGGAGGAGAATGCAGAGCAGGCTTCCGCCTTTC
TTGCCCGGTCGCCTCAGTTCAGCGCTGCCGATCACGGGGCTCTCTGGCGCGAACGCTTCAATAGCGCGGCGGCAGAGCCG
CGCATCGGGAACGGCATAACGCTGACGCCTGCCACCACCGGCACAGACGGCTTCTACTTCGCCTGCTTCGGGCGCGCAGC
CTAG

Upstream 100 bases:

>100_bases
CACGCGCGAGGCAATCCCGGAGCTTTTGTCTTTAGCCCTTGTGAATTATTCCACCAGGCGTTAGCCAAGGCCCAAGACGG
GTTTACCGGAAAGGCTCCAC

Downstream 100 bases:

>100_bases
AGCCCGTTATGGCACCGGCATACGCGGTACGCTCGCGAGCAGCTTCTGCGTGTATGGATGCTGCGGGCGGGCCAAAATCT
CGGATGTGCGGCCGCTTTCC

Product: Fmu (Sun)

Products: NA

Alternate protein names: 16S rRNA m5C967 methyltransferase; rRNA (cytosine-C(5)-)-methyltransferase rsmB [H]

Number of amino acids: Translated: 427; Mature: 427

Protein sequence:

>427_residues
MRLGGRLAAAIEILEDIETRHRPAADAMRDWGLSHRFAGAGDRAAIGNFVYDALRRRRAAAWIFDADSPRTLVLGSYLLE
SGVLPQELGRLIADDRFAPSMLTEAELAALQARLSEELPAPARANAPEWCEPLMEEAFGAAWVDEGAALASRPPLDMRVN
RLKASREKVLASLARAGAKPARIAPSGLRIAPISGDGRHPNIQAEPAFQKGWFEVQDEGSQIVAELAGPAQGSQVLDFCA
GAGGKTLAFSAMMDNRGQIYAFDADKQRLAPIFDRLKRAGCRNVQVIADEGQLTRLEGQMDLVVVDAPCTGSGTWRRRPD
AKWRLTAQQLEARRAEQATILDAASRYVKPGGRLAYITCSIFQEENAEQASAFLARSPQFSAADHGALWRERFNSAAAEP
RIGNGITLTPATTGTDGFYFACFGRAA

Sequences:

>Translated_427_residues
MRLGGRLAAAIEILEDIETRHRPAADAMRDWGLSHRFAGAGDRAAIGNFVYDALRRRRAAAWIFDADSPRTLVLGSYLLE
SGVLPQELGRLIADDRFAPSMLTEAELAALQARLSEELPAPARANAPEWCEPLMEEAFGAAWVDEGAALASRPPLDMRVN
RLKASREKVLASLARAGAKPARIAPSGLRIAPISGDGRHPNIQAEPAFQKGWFEVQDEGSQIVAELAGPAQGSQVLDFCA
GAGGKTLAFSAMMDNRGQIYAFDADKQRLAPIFDRLKRAGCRNVQVIADEGQLTRLEGQMDLVVVDAPCTGSGTWRRRPD
AKWRLTAQQLEARRAEQATILDAASRYVKPGGRLAYITCSIFQEENAEQASAFLARSPQFSAADHGALWRERFNSAAAEP
RIGNGITLTPATTGTDGFYFACFGRAA
>Mature_427_residues
MRLGGRLAAAIEILEDIETRHRPAADAMRDWGLSHRFAGAGDRAAIGNFVYDALRRRRAAAWIFDADSPRTLVLGSYLLE
SGVLPQELGRLIADDRFAPSMLTEAELAALQARLSEELPAPARANAPEWCEPLMEEAFGAAWVDEGAALASRPPLDMRVN
RLKASREKVLASLARAGAKPARIAPSGLRIAPISGDGRHPNIQAEPAFQKGWFEVQDEGSQIVAELAGPAQGSQVLDFCA
GAGGKTLAFSAMMDNRGQIYAFDADKQRLAPIFDRLKRAGCRNVQVIADEGQLTRLEGQMDLVVVDAPCTGSGTWRRRPD
AKWRLTAQQLEARRAEQATILDAASRYVKPGGRLAYITCSIFQEENAEQASAFLARSPQFSAADHGALWRERFNSAAAEP
RIGNGITLTPATTGTDGFYFACFGRAA

Specific function: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA [H]

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI76150625, Length=282, Percent_Identity=28.0141843971631, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI76150623, Length=282, Percent_Identity=28.0141843971631, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI8922322, Length=299, Percent_Identity=29.0969899665552, Blast_Score=89, Evalue=8e-18,
Organism=Homo sapiens, GI270288818, Length=299, Percent_Identity=29.0969899665552, Blast_Score=89, Evalue=9e-18,
Organism=Homo sapiens, GI23199998, Length=234, Percent_Identity=30.3418803418803, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI270288816, Length=299, Percent_Identity=29.0969899665552, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI32698918, Length=181, Percent_Identity=27.0718232044199, Blast_Score=82, Evalue=9e-16,
Organism=Escherichia coli, GI2367212, Length=307, Percent_Identity=32.8990228013029, Blast_Score=149, Evalue=5e-37,
Organism=Escherichia coli, GI87081985, Length=216, Percent_Identity=31.4814814814815, Blast_Score=87, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17536757, Length=286, Percent_Identity=27.6223776223776, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71998419, Length=241, Percent_Identity=28.6307053941909, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI115534021, Length=238, Percent_Identity=27.7310924369748, Blast_Score=77, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6324268, Length=284, Percent_Identity=29.2253521126761, Blast_Score=107, Evalue=5e-24,
Organism=Drosophila melanogaster, GI21356579, Length=233, Percent_Identity=29.1845493562232, Blast_Score=101, Evalue=9e-22,
Organism=Drosophila melanogaster, GI22024126, Length=286, Percent_Identity=26.2237762237762, Blast_Score=94, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR006027
- InterPro:   IPR004573 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu; PF01029 NusB [H]

EC number: =2.1.1.176 [H]

Molecular weight: Translated: 46262; Mature: 46262

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLGGRLAAAIEILEDIETRHRPAADAMRDWGLSHRFAGAGDRAAIGNFVYDALRRRRAA
CCCCHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHE
AWIFDADSPRTLVLGSYLLESGVLPQELGRLIADDRFAPSMLTEAELAALQARLSEELPA
EEEEECCCCCEEEHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCC
PARANAPEWCEPLMEEAFGAAWVDEGAALASRPPLDMRVNRLKASREKVLASLARAGAKP
CCCCCCHHHHHHHHHHHCCCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
ARIAPSGLRIAPISGDGRHPNIQAEPAFQKGWFEVQDEGSQIVAELAGPAQGSQVLDFCA
CCCCCCCCEEEECCCCCCCCCCCCCCCHHCCCEEECCCHHHHHHHHCCCCCCHHHHHHHH
GAGGKTLAFSAMMDNRGQIYAFDADKQRLAPIFDRLKRAGCRNVQVIADEGQLTRLEGQM
CCCCCEEEEEEEECCCCCEEEECCCHHHHHHHHHHHHHCCCCCEEEEECCCCEEEECCCE
DLVVVDAPCTGSGTWRRRPDAKWRLTAQQLEARRAEQATILDAASRYVKPGGRLAYITCS
EEEEEECCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEE
IFQEENAEQASAFLARSPQFSAADHGALWRERFNSAAAEPRIGNGITLTPATTGTDGFYF
ECCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCEEE
ACFGRAA
EEECCCC
>Mature Secondary Structure
MRLGGRLAAAIEILEDIETRHRPAADAMRDWGLSHRFAGAGDRAAIGNFVYDALRRRRAA
CCCCHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHE
AWIFDADSPRTLVLGSYLLESGVLPQELGRLIADDRFAPSMLTEAELAALQARLSEELPA
EEEEECCCCCEEEHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCC
PARANAPEWCEPLMEEAFGAAWVDEGAALASRPPLDMRVNRLKASREKVLASLARAGAKP
CCCCCCHHHHHHHHHHHCCCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
ARIAPSGLRIAPISGDGRHPNIQAEPAFQKGWFEVQDEGSQIVAELAGPAQGSQVLDFCA
CCCCCCCCEEEECCCCCCCCCCCCCCCHHCCCEEECCCHHHHHHHHCCCCCCHHHHHHHH
GAGGKTLAFSAMMDNRGQIYAFDADKQRLAPIFDRLKRAGCRNVQVIADEGQLTRLEGQM
CCCCCEEEEEEEECCCCCEEEECCCHHHHHHHHHHHHHCCCCCEEEEECCCCEEEECCCE
DLVVVDAPCTGSGTWRRRPDAKWRLTAQQLEARRAEQATILDAASRYVKPGGRLAYITCS
EEEEEECCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEE
IFQEENAEQASAFLARSPQFSAADHGALWRERFNSAAAEPRIGNGITLTPATTGTDGFYF
ECCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCEEE
ACFGRAA
EEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]