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The map label for this gene is queF

Identifier: 110632803

GI number: 110632803

Start: 489129

End: 489590

Strand: Reverse

Name: queF

Synonym: Meso_0442

Alternate gene names: 110632803

Gene position: 489590-489129 (Counterclockwise)

Preceding gene: 110632806

Following gene: 110632802

Centisome position: 11.1

GC content: 62.99

Gene sequence:

>462_bases
ATGACCGATACCCGCAACCTGACGCAGCTCGGGAGCAAAACGCAAGCGCCCGCCTCTCCGGAAGCTGCCACGCTCGAGAC
GGCGCCATTTTCCCGCGGCGACGGGCCGGCGGCAATCGTCCGCTTCACCTGCCCGGAATTCACGTCGCTCTGCCCGGTAA
CGGGCCAACCGGACTTTGCTCATATCGTGATCGATTACGCGCCGGACAAGCTTCTGGTGGAATCGAAATCGCTGAAGCTC
TTCCTCACCTCTTTCCGCAATCATGGCGCCTTCCATGAGGATTGCACGGTGATGATCGGCAGGCGCATCGTGGAAGCGAC
CAAGCCTCTCTGGCTCAGAATCGGCGGCTATTGGTATCCGCGCGGCGGCATCCCCATCGACGTCTTCTGGCAGACGGGCA
CGCCACCAAAGGACGCCTGGGTTCCCGAAACAGGCGTGCCGCCCTATCGAGGGCGGGGCTGA

Upstream 100 bases:

>100_bases
ATCCGTCAAATGCGGAGCTGCGGTCGCGGCTATTTCCGTTCCATTCGACCGGGCGAAGGCATATAAGGCCGCCGACACAG
AACCAAAGGGAGTCATTCCC

Downstream 100 bases:

>100_bases
ACCCACCTGACATTCCTGCCGCCAGCCCAGGCTGATGGGGCATCTCCCTCGGCTGGTGAAAGGCAAATCCCTGGGGTTTC
AAAGCCTGGCGCTTAGGATT

Product: 7-cyano-7-deazaguanine reductase

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine reductase; NADPH-dependent nitrile oxidoreductase; PreQ(0) reductase

Number of amino acids: Translated: 153; Mature: 152

Protein sequence:

>153_residues
MTDTRNLTQLGSKTQAPASPEAATLETAPFSRGDGPAAIVRFTCPEFTSLCPVTGQPDFAHIVIDYAPDKLLVESKSLKL
FLTSFRNHGAFHEDCTVMIGRRIVEATKPLWLRIGGYWYPRGGIPIDVFWQTGTPPKDAWVPETGVPPYRGRG

Sequences:

>Translated_153_residues
MTDTRNLTQLGSKTQAPASPEAATLETAPFSRGDGPAAIVRFTCPEFTSLCPVTGQPDFAHIVIDYAPDKLLVESKSLKL
FLTSFRNHGAFHEDCTVMIGRRIVEATKPLWLRIGGYWYPRGGIPIDVFWQTGTPPKDAWVPETGVPPYRGRG
>Mature_152_residues
TDTRNLTQLGSKTQAPASPEAATLETAPFSRGDGPAAIVRFTCPEFTSLCPVTGQPDFAHIVIDYAPDKLLVESKSLKLF
LTSFRNHGAFHEDCTVMIGRRIVEATKPLWLRIGGYWYPRGGIPIDVFWQTGTPPKDAWVPETGVPPYRGRG

Specific function: Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)

COG id: COG0780

COG function: function code R; Enzyme related to GTP cyclohydrolase I

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): QUEF_MESSB (Q11L79)

Other databases:

- EMBL:   CP000390
- RefSeq:   YP_673011.1
- ProteinModelPortal:   Q11L79
- SMR:   Q11L79
- STRING:   Q11L79
- GeneID:   4179983
- GenomeReviews:   CP000390_GR
- KEGG:   mes:Meso_0442
- NMPDR:   fig|266779.1.peg.2589
- eggNOG:   COG0780
- HOGENOM:   HBG294103
- OMA:   HIVIDYA
- ProtClustDB:   PRK13258
- BioCyc:   MSP266779:MESO_0442-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00818
- InterPro:   IPR016856
- InterPro:   IPR020602
- PIRSF:   PIRSF027377
- TIGRFAMs:   TIGR03139

Pfam domain/function: PF01227 GTP_cyclohydroI

EC number: =1.7.1.13

Molecular weight: Translated: 16846; Mature: 16715

Theoretical pI: Translated: 8.06; Mature: 8.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDTRNLTQLGSKTQAPASPEAATLETAPFSRGDGPAAIVRFTCPEFTSLCPVTGQPDFA
CCCCCCHHHHCCCCCCCCCCCCCEEECCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCEE
HIVIDYAPDKLLVESKSLKLFLTSFRNHGAFHEDCTVMIGRRIVEATKPLWLRIGGYWYP
EEEEEECCCEEEEECCCEEEEEEEHHCCCCCCCCHHHHHHHHHHHCCCCEEEEECCEEEC
RGGIPIDVFWQTGTPPKDAWVPETGVPPYRGRG
CCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TDTRNLTQLGSKTQAPASPEAATLETAPFSRGDGPAAIVRFTCPEFTSLCPVTGQPDFA
CCCCCHHHHCCCCCCCCCCCCCEEECCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCEE
HIVIDYAPDKLLVESKSLKLFLTSFRNHGAFHEDCTVMIGRRIVEATKPLWLRIGGYWYP
EEEEEECCCEEEEECCCEEEEEEEHHCCCCCCCCHHHHHHHHHHHCCCCEEEEECCEEEC
RGGIPIDVFWQTGTPPKDAWVPETGVPPYRGRG
CCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA