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The map label for this gene is cnrH [H]

Identifier: 110632508

GI number: 110632508

Start: 181138

End: 181641

Strand: Reverse

Name: cnrH [H]

Synonym: Meso_0146

Alternate gene names: 110632508

Gene position: 181641-181138 (Counterclockwise)

Preceding gene: 110632509

Following gene: 110632507

Centisome position: 4.12

GC content: 62.7

Gene sequence:

>504_bases
ATGTCGCAGATCCTGGACGAGATCGAGGAATGCGTGCCAGCGCTGAGGCGCTATGCCCGAGCTCTGACGCACGATGCAGA
TCACGCGGATGATCTCGTCCAGGACTGTCTCGAACGCGCCATTCGCAAGCGCGCACTCTGGAAACCATCGGGTTCCCTGC
GCTCTTGGATGTTCCGTATCCTGCTCAATCTCTACCGAAACGATATGAGGCGGCGCAGGCATGCGCCTGATCTGCCTCTC
GACGTGCTTGCGGCGGACCCGCCGGGCCCCGATACGCAATCGGGCCGGCTGGCGCTTGCCGAAACAGCGCGGGCGATGCA
GTCGCTGCCGGCGGAGCAAAGGGAAGTGCTTCTTCTCGTGGCTGTCGAGCAAATGAGCTATGCCGAGGCAGCGGAGGTCC
TTTCTCTTCCGCTGGGCACCATTATGTCGCGCTTGGGACGGGCGCGTGCAACATTGAGGCGTCTGACGGAGGCGGGCGCG
CCGAAACTGAGGTCCGTGAAATGA

Upstream 100 bases:

>100_bases
TAAAGGCATGCCGCTCTACCTCTGGAAGAACGACAAAAAGCCGGGTGACGTAACGGGAGACGGCGTAGGCGGGGTCTGGC
ACCTCGCAAAAGAGTAGGGC

Downstream 100 bases:

>100_bases
GCCGCAGGGAAAGCAAGATCACAGAGCACGACCTGCACGCCTACGCCGACGGCGCCCTCGTAGATCCGAAACGCCAGGAG
GTCGAAGCACATCTTGCCGC

Product: ECF subfamily RNA polymerase sigma-24 factor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 167; Mature: 166

Protein sequence:

>167_residues
MSQILDEIEECVPALRRYARALTHDADHADDLVQDCLERAIRKRALWKPSGSLRSWMFRILLNLYRNDMRRRRHAPDLPL
DVLAADPPGPDTQSGRLALAETARAMQSLPAEQREVLLLVAVEQMSYAEAAEVLSLPLGTIMSRLGRARATLRRLTEAGA
PKLRSVK

Sequences:

>Translated_167_residues
MSQILDEIEECVPALRRYARALTHDADHADDLVQDCLERAIRKRALWKPSGSLRSWMFRILLNLYRNDMRRRRHAPDLPL
DVLAADPPGPDTQSGRLALAETARAMQSLPAEQREVLLLVAVEQMSYAEAAEVLSLPLGTIMSRLGRARATLRRLTEAGA
PKLRSVK
>Mature_166_residues
SQILDEIEECVPALRRYARALTHDADHADDLVQDCLERAIRKRALWKPSGSLRSWMFRILLNLYRNDMRRRRHAPDLPLD
VLAADPPGPDTQSGRLALAETARAMQSLPAEQREVLLLVAVEQMSYAEAAEVLSLPLGTIMSRLGRARATLRRLTEAGAP
KLRSVK

Specific function: CnrH alone is able to activate CNR expression, while both CnrY and CrnX are needed for nickel induction of cnrH (PubMed:10671463). Binds DNA in a RNA polymerase-dependent fashion (PubMed:10671464). CnrH may be controlled by a CnrYX transmembrane anti-sigm

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR013325
- InterPro:   IPR013324 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 18791; Mature: 18660

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQILDEIEECVPALRRYARALTHDADHADDLVQDCLERAIRKRALWKPSGSLRSWMFRI
CHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
LLNLYRNDMRRRRHAPDLPLDVLAADPPGPDTQSGRLALAETARAMQSLPAEQREVLLLV
HHHHHHHHHHHHHCCCCCCHHHEECCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHH
AVEQMSYAEAAEVLSLPLGTIMSRLGRARATLRRLTEAGAPKLRSVK
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SQILDEIEECVPALRRYARALTHDADHADDLVQDCLERAIRKRALWKPSGSLRSWMFRI
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
LLNLYRNDMRRRRHAPDLPLDVLAADPPGPDTQSGRLALAETARAMQSLPAEQREVLLLV
HHHHHHHHHHHHHCCCCCCHHHEECCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHH
AVEQMSYAEAAEVLSLPLGTIMSRLGRARATLRRLTEAGAPKLRSVK
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8380802; 8052622; 10671463; 10671464 [H]