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The map label for this gene is yscU [H]

Identifier: 110632475

GI number: 110632475

Start: 140331

End: 141350

Strand: Direct

Name: yscU [H]

Synonym: Meso_0113

Alternate gene names: 110632475

Gene position: 140331-141350 (Clockwise)

Preceding gene: 110632474

Following gene: 110632476

Centisome position: 3.18

GC content: 53.53

Gene sequence:

>1020_bases
ATGAGCGGCGAAAAGACGGAAGCCCCGACGCCGCGCAGGCTCGAGGAGCGGCGCAGGGAAGGGCAGGTCCCCCAACGAAA
AAATATTATCGAAGCTGCCCTGCTGACATTCGTTGTCGTGCTCTTGATCTGGCTCTTCCGCCCACTCTCGGAAGCATTGC
TAAACCTCTCCGCAGCAGTCTTCTCCAGCATCAGCCACGATTTAGAAGCAGCAACGGCAACGAGCCTCGTCGCGGCTATG
CCGGTGGTTCACTGGATGCTGGCAATTTGCGGTGCAAGCGCCTTGTTCACATTGCTGCTAAGTTGCGTGCTCAATAAATT
TATGTTTGCACCGAAGGCATTGGCTCCAAAATTCGAACGCTTCAATCCCGTCGGCCAGATCAAGAGCATTTTTTCGAAGG
CGACCCTATACAGCTTCATGCGGATGATTGTGCTGTTCACGGCCGTATCTGCGATCTTTATATATCTATACGTAGCCAAC
ATGGATAACTCTCTGCAGGCTAGTCACTGCGGAGAAGCGTGCCTCTATGATCTGTTCACGTCACGAATCGGAATGCTCGT
CGCTGCAGTATTAGGGGTTCTGATCGTGCTGGCGCTGATTGATTATAAAATACAAGACCGAATGTTTATCTCTCAGAACA
AGATGACGAAGGAGGAAGTGAAGAGGGAGTACAAGGACCAGGAGGGTGATCGGGAAATAAAGGCCGGACGTAAATCGATC
GCCTTGAATGATGCTGCGGCCCCCCTGCTTTCCGAATCCACTCACGTGGTGCACAGTGACCAGGTGCTTGCGGCGGTTAT
ATTTTATCCGGGGGCCGGATACCCTCCCTATCTCGTTTTCAAGGCAATGGGGGCGAGCGTGCCGGGATTGTGCAGGAAGT
TTCTCGCCATGAACATTCCGACGTTTAATGTTCCGGGGGCGGCGTTGGAATTCTACCGGATGTCGGCACCTGGGCAGTAT
CTGCCGGCCAGGTCCATACGCAGCATGGAGAAGATATTGGGCAGGACTGCGGGCGGTTAA

Upstream 100 bases:

>100_bases
TCCTTCTGGTCATGCTGATTTTCTACATTGCCCTCCTTTATCCCAAGCTCTGGGAGACAGTGGCCGGTTCTTTGGTACTG
ATGCAGCAGGTTCTCGGATT

Downstream 100 bases:

>100_bases
CAGCCGGTGCGTGCGATCAGCAGTCAGATTTTGTGTGGATATCCTTCGAGTAAACCAGAACGCGGTTCACATGCGCGCGC
ACTTGTGACGGAACTGAGAT

Product: type III secretion exporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 339; Mature: 338

Protein sequence:

>339_residues
MSGEKTEAPTPRRLEERRREGQVPQRKNIIEAALLTFVVVLLIWLFRPLSEALLNLSAAVFSSISHDLEAATATSLVAAM
PVVHWMLAICGASALFTLLLSCVLNKFMFAPKALAPKFERFNPVGQIKSIFSKATLYSFMRMIVLFTAVSAIFIYLYVAN
MDNSLQASHCGEACLYDLFTSRIGMLVAAVLGVLIVLALIDYKIQDRMFISQNKMTKEEVKREYKDQEGDREIKAGRKSI
ALNDAAAPLLSESTHVVHSDQVLAAVIFYPGAGYPPYLVFKAMGASVPGLCRKFLAMNIPTFNVPGAALEFYRMSAPGQY
LPARSIRSMEKILGRTAGG

Sequences:

>Translated_339_residues
MSGEKTEAPTPRRLEERRREGQVPQRKNIIEAALLTFVVVLLIWLFRPLSEALLNLSAAVFSSISHDLEAATATSLVAAM
PVVHWMLAICGASALFTLLLSCVLNKFMFAPKALAPKFERFNPVGQIKSIFSKATLYSFMRMIVLFTAVSAIFIYLYVAN
MDNSLQASHCGEACLYDLFTSRIGMLVAAVLGVLIVLALIDYKIQDRMFISQNKMTKEEVKREYKDQEGDREIKAGRKSI
ALNDAAAPLLSESTHVVHSDQVLAAVIFYPGAGYPPYLVFKAMGASVPGLCRKFLAMNIPTFNVPGAALEFYRMSAPGQY
LPARSIRSMEKILGRTAGG
>Mature_338_residues
SGEKTEAPTPRRLEERRREGQVPQRKNIIEAALLTFVVVLLIWLFRPLSEALLNLSAAVFSSISHDLEAATATSLVAAMP
VVHWMLAICGASALFTLLLSCVLNKFMFAPKALAPKFERFNPVGQIKSIFSKATLYSFMRMIVLFTAVSAIFIYLYVANM
DNSLQASHCGEACLYDLFTSRIGMLVAAVLGVLIVLALIDYKIQDRMFISQNKMTKEEVKREYKDQEGDREIKAGRKSIA
LNDAAAPLLSESTHVVHSDQVLAAVIFYPGAGYPPYLVFKAMGASVPGLCRKFLAMNIPTFNVPGAALEFYRMSAPGQYL
PARSIRSMEKILGRTAGG

Specific function: Component of the yop secretion machinery [H]

COG id: COG4792

COG function: function code U; Type III secretory pathway, component EscU

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III secretion exporter family [H]

Homologues:

Organism=Escherichia coli, GI1788188, Length=371, Percent_Identity=26.4150943396226, Blast_Score=91, Evalue=8e-20,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006135
- InterPro:   IPR006307 [H]

Pfam domain/function: PF01312 Bac_export_2 [H]

EC number: NA

Molecular weight: Translated: 37356; Mature: 37225

Theoretical pI: Translated: 9.57; Mature: 9.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGEKTEAPTPRRLEERRREGQVPQRKNIIEAALLTFVVVLLIWLFRPLSEALLNLSAAV
CCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FSSISHDLEAATATSLVAAMPVVHWMLAICGASALFTLLLSCVLNKFMFAPKALAPKFER
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHH
FNPVGQIKSIFSKATLYSFMRMIVLFTAVSAIFIYLYVANMDNSLQASHCGEACLYDLFT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
SRIGMLVAAVLGVLIVLALIDYKIQDRMFISQNKMTKEEVKREYKDQEGDREIKAGRKSI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHCCHHH
ALNDAAAPLLSESTHVVHSDQVLAAVIFYPGAGYPPYLVFKAMGASVPGLCRKFLAMNIP
CCCHHHHHHHCCCCCCEEHHHHHHHHHCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHCCC
TFNVPGAALEFYRMSAPGQYLPARSIRSMEKILGRTAGG
CCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SGEKTEAPTPRRLEERRREGQVPQRKNIIEAALLTFVVVLLIWLFRPLSEALLNLSAAV
CCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH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CCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9746557; 9748454; 11586360 [H]