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The map label for this gene is holB

Identifier: 109948122

GI number: 109948122

Start: 1431436

End: 1432089

Strand: Reverse

Name: holB

Synonym: Hac_1644

Alternate gene names: NA

Gene position: 1432089-1431436 (Counterclockwise)

Preceding gene: 109948123

Following gene: 109948121

Centisome position: 92.16

GC content: 34.4

Gene sequence:

>654_bases
ATGAAAAATTTCAACCGCCTTATTTATACGGACAATCTTGAAGAAAGCTTAGAAGAAGTTGCAAGCCTTTTTGAACGCCA
CACTAAATTCTACACAGAAATCCTTGAAAAAGACAAAAAGGTGATCAAAACTTTTAACAAGGACTTTAAAATAGAGCATG
CCAAAGAAGTGATTTCAAAAGCCAATCTCAAACACAGCACATTGAACGCCTTTTTAATCGCTGCCCCTAGTTATGGTATA
GAAGCCCAAAACGCGCTCTTAAAAATATTAGAAGAACCCCCAAATAATGTTTGTTTTATCATGTTTGCTAAAAGCCCAAA
CCATGTCTTAGCTACCATTAAATCCCGCTTAATCAAAGAAGATAGGCGCCAAAAAATCCCTCTAAAACCTTTAAATTTTG
ATTTATCCAAGTTGGATTTAAAAGATATTTATGCGTTTTTAAGGGAATTAGACAAAGAAAATTTTGATTCTAGAGAAAAT
CAAAGGGAAAAAATTGAAAGCCTGCTAGAGAGCATCAACAGACACCAGATCTATTTAAACGAGCAAGAATTGCAAGCTTT
TGATTTAGCGATCAAGGCCAATAGCTCTTATTATAAGCTTAGCTATAATCTTTTGCCCTTACTTTTAAGCCTTTTGTCTA
AAAAGAGGGTGTGA

Upstream 100 bases:

>100_bases
TTTTAAAAGAGCATGATAGTTTGTTAGATTATAAATTATTGCAACTCTTCAAACTCTTTGAAAACGCGCTTTTTAGCGTG
CTATACAATAAGGTTACTTT

Downstream 100 bases:

>100_bases
TGACTTTAAAACGCCTTAATTCTGATGCGTTAAAAAACGCCCTTCAAAAAATAGGTCCAGAAAAGATCGTGCAAAACCGC
ATGCACCAAAAAGGCGTTAG

Product: DNA polymerase III subunit delta'

Products: diphosphate; DNAn+1

Alternate protein names: DNA Polymerase III Delta Prime Subunit HolB; DNA Polymerase III Delta Prime Subunit; DNA Polymerase III Delta Prime Subunit Holb; DNA Polymerase III Delta Subunit

Number of amino acids: Translated: 217; Mature: 217

Protein sequence:

>217_residues
MKNFNRLIYTDNLEESLEEVASLFERHTKFYTEILEKDKKVIKTFNKDFKIEHAKEVISKANLKHSTLNAFLIAAPSYGI
EAQNALLKILEEPPNNVCFIMFAKSPNHVLATIKSRLIKEDRRQKIPLKPLNFDLSKLDLKDIYAFLRELDKENFDSREN
QREKIESLLESINRHQIYLNEQELQAFDLAIKANSSYYKLSYNLLPLLLSLLSKKRV

Sequences:

>Translated_217_residues
MKNFNRLIYTDNLEESLEEVASLFERHTKFYTEILEKDKKVIKTFNKDFKIEHAKEVISKANLKHSTLNAFLIAAPSYGI
EAQNALLKILEEPPNNVCFIMFAKSPNHVLATIKSRLIKEDRRQKIPLKPLNFDLSKLDLKDIYAFLRELDKENFDSREN
QREKIESLLESINRHQIYLNEQELQAFDLAIKANSSYYKLSYNLLPLLLSLLSKKRV
>Mature_217_residues
MKNFNRLIYTDNLEESLEEVASLFERHTKFYTEILEKDKKVIKTFNKDFKIEHAKEVISKANLKHSTLNAFLIAAPSYGI
EAQNALLKILEEPPNNVCFIMFAKSPNHVLATIKSRLIKEDRRQKIPLKPLNFDLSKLDLKDIYAFLRELDKENFDSREN
QREKIESLLESINRHQIYLNEQELQAFDLAIKANSSYYKLSYNLLPLLLSLLSKKRV

Specific function: Unknown

COG id: COG0470

COG function: function code L; ATPase involved in DNA replication

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.7.7.7

Molecular weight: Translated: 25463; Mature: 25463

Theoretical pI: Translated: 9.39; Mature: 9.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNFNRLIYTDNLEESLEEVASLFERHTKFYTEILEKDKKVIKTFNKDFKIEHAKEVISK
CCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
ANLKHSTLNAFLIAAPSYGIEAQNALLKILEEPPNNVCFIMFAKSPNHVLATIKSRLIKE
CCCCHHHHHEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHH
DRRQKIPLKPLNFDLSKLDLKDIYAFLRELDKENFDSRENQREKIESLLESINRHQIYLN
HHHCCCCCCCCCCCHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEEC
EQELQAFDLAIKANSSYYKLSYNLLPLLLSLLSKKRV
HHHHHHHHEEEECCCCEEEEHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKNFNRLIYTDNLEESLEEVASLFERHTKFYTEILEKDKKVIKTFNKDFKIEHAKEVISK
CCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
ANLKHSTLNAFLIAAPSYGIEAQNALLKILEEPPNNVCFIMFAKSPNHVLATIKSRLIKE
CCCCHHHHHEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHH
DRRQKIPLKPLNFDLSKLDLKDIYAFLRELDKENFDSRENQREKIESLLESINRHQIYLN
HHHCCCCCCCCCCCHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEEC
EQELQAFDLAIKANSSYYKLSYNLLPLLLSLLSKKRV
HHHHHHHHEEEECCCCEEEEHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: deoxynucleoside triphosphate; DNAn

Specific reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA