Click here to switch to the map view.

The map label for this gene is dxr fragment 1 [H]

Identifier: 109947995

GI number: 109947995

Start: 1305272

End: 1305670

Strand: Reverse

Name: dxr fragment 1 [H]

Synonym: Hac_1503

Alternate gene names: 109947995

Gene position: 1305670-1305272 (Counterclockwise)

Preceding gene: 109947996

Following gene: 109947994

Centisome position: 84.02

GC content: 40.35

Gene sequence:

>399_bases
ATGGTTGTTTTAGGGAGCACCGGCTCTGTTGGGAAAAACGCCCTTAATATCGCAACAAAATTTGGCGTAAAAATAGAAGC
GTTAAGTTGCGGGAAGAATATCGCTTTAATCAATGAGCAAATTAAAATATTCAAACCCAAAAAAGTGGCGATTTTAGATC
CTAACGATTTGAATCTTTTAGAGCCTTTGGGCGCGAAAGTGTTTGTGGGACTAGACGGCATTGATGCGATGATAGAAGAG
TGCACTTCTCATTTAGTCCTTAACGCTATTGTGGGCGTGGCTGGATTGAGAGCGAGCTTTAAAAGCTTACAAAGGAATAA
AAAACTAGCCCTAGCGAATAAAGAAAGTTTTAGTGAGCGCAGGGCATTTATTAGACATTTCACAAATCACACCCGTTGA

Upstream 100 bases:

>100_bases
AGACAGATTAGATTCCATGCTTTTTGGGGCTTTGAGCTTGCATGTGTTGTTGTATTTTTTAGAAGTTTGGAAAGAGACGG
CGGTGTTTTTAGGGGATTAA

Downstream 100 bases:

>100_bases
TAGCGAGCATTTTGGCTTGTGGGCGTTGTTGCAAAACAAGGCTTTGAAACCCAAATCTTTAATCATTAGCGCTAGTGGGG
GGGCTTTTAGGGACACGCCT

Product: 1-deoxy-D-xylulose 5-phosphate reductoisomerase

Products: NA

Alternate protein names: DXP reductoisomerase; 1-deoxyxylulose-5-phosphate reductoisomerase; 2-C-methyl-D-erythritol 4-phosphate synthase [H]

Number of amino acids: Translated: 132; Mature: 132

Protein sequence:

>132_residues
MVVLGSTGSVGKNALNIATKFGVKIEALSCGKNIALINEQIKIFKPKKVAILDPNDLNLLEPLGAKVFVGLDGIDAMIEE
CTSHLVLNAIVGVAGLRASFKSLQRNKKLALANKESFSERRAFIRHFTNHTR

Sequences:

>Translated_132_residues
MVVLGSTGSVGKNALNIATKFGVKIEALSCGKNIALINEQIKIFKPKKVAILDPNDLNLLEPLGAKVFVGLDGIDAMIEE
CTSHLVLNAIVGVAGLRASFKSLQRNKKLALANKESFSERRAFIRHFTNHTR
>Mature_132_residues
MVVLGSTGSVGKNALNIATKFGVKIEALSCGKNIALINEQIKIFKPKKVAILDPNDLNLLEPLGAKVFVGLDGIDAMIEE
CTSHLVLNAIVGVAGLRASFKSLQRNKKLALANKESFSERRAFIRHFTNHTR

Specific function: Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) [H]

COG id: COG0743

COG function: function code I; 1-deoxy-D-xylulose 5-phosphate reductoisomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DXR family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003821
- InterPro:   IPR013644
- InterPro:   IPR013512
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08436 DXP_redisom_C; PF02670 DXP_reductoisom [H]

EC number: =1.1.1.267 [H]

Molecular weight: Translated: 14328; Mature: 14328

Theoretical pI: Translated: 10.59; Mature: 10.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVLGSTGSVGKNALNIATKFGVKIEALSCGKNIALINEQIKIFKPKKVAILDPNDLNLL
CEEECCCCCCCCHHHHHHHHCCEEEEEECCCCEEEEECCCEEEECCCEEEEECCCCCCHH
EPLGAKVFVGLDGIDAMIEECTSHLVLNAIVGVAGLRASFKSLQRNKKLALANKESFSER
CCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHH
RAFIRHFTNHTR
HHHHHHHHCCCC
>Mature Secondary Structure
MVVLGSTGSVGKNALNIATKFGVKIEALSCGKNIALINEQIKIFKPKKVAILDPNDLNLL
CEEECCCCCCCCHHHHHHHHCCEEEEEECCCCEEEEECCCEEEECCCEEEEECCCCCCHH
EPLGAKVFVGLDGIDAMIEECTSHLVLNAIVGVAGLRASFKSLQRNKKLALANKESFSER
CCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHH
RAFIRHFTNHTR
HHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA