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The map label for this gene is neuB

Identifier: 109947792

GI number: 109947792

Start: 1093937

End: 1094974

Strand: Reverse

Name: neuB

Synonym: Hac_1271

Alternate gene names: NA

Gene position: 1094974-1093937 (Counterclockwise)

Preceding gene: 109947793

Following gene: 109947791

Centisome position: 70.46

GC content: 40.56

Gene sequence:

>1038_bases
ATGGATTTTATTTTAGGCACTAGAAAAATTGGTATCAACCACACGCCTTTGGTGGTGGCTGAAATTGGGATTAATCATAA
TGGCAGTTTAGAAATCGCTAAACTCATGGTAGATGCGGCTAAAAGGGTTGGCATTGAGGTTATTAAACACCAAACGCATA
TCATTGAAGATGAAATGAGTATCAGCGCTTTAAAGGTCATTCCTGGCAATAGTGAGTTAAGCATTTATGAGATCATGAAA
AAATGTGCTTTGAGCAAAAACGATGAAAGGGAGTTGAAAGAATACACAGAAAAACAAGGGCTGATTTTTCTTTCTACACC
TTTTAGTAGGGCGGCGGCGAATTTTTTGGAAGATCTAGGTGTTGTGGGCTATAAAATAGGCTCTGGTGAAATGAATAATA
CCCCTTTGTTAAAGCATATCGCTAATTTTAAAAAGCCCATGATTATTTCTACTGGGATGCATGATTTAGAGAGCGTGAAA
GAGTGCATAAACCCGATTATAGACAAAGTGCCAATCGCACTTTTGCACACGACGAATCTCTACCCCACGCCCTTTGAATT
GGTGCGATTAAACGCCATGCTGGATTTAAAAAACGCTTTTAAGGTGCCGGTGGGTTTGAGCGATCACACTTTAAACAACA
ACGCTTGCAAGAGCGCTATCGCCCTTGGAGCTAGCATAGTGGAGCGGCATTTTACGGACACTAAAGACAGGGAGGGGCCT
GATATTGTTTGCTCTATGGATGAAGAAGAAGCTAAAGATTTAGTCAAAAGCGCTCAAGAGATTTTTTTAATGCGTGGGGG
GAGCAAGACTAAAATCAAAGAAGAGCAAGTCACGCGAGATTTTGCATTTGCTACTATGGTGGCTATCAAACGCATCAAAA
AAGGCGAAAAAATCACTGAGAGTAATGCATGGGTGAAACGCCCAGGGGTTAAAGGCATTTTGGCGAAGGATTATGAAAAG
ACTTTGGGTAGAGTGGCTAAAATAGATATTGGCATAGACGAACACATTTGCGATGAAATGCTAGAAAATAAGGAATAA

Upstream 100 bases:

>100_bases
AAAGTCAAATACCTTTAAATAGCTTAAAATTTAAGATTAAATTAAGTTTTTATACCAAATATTGGTGAGAATAAGCTATG
ATTATCAAAAAGGTTTTGCA

Downstream 100 bases:

>100_bases
AAGATACTAATGGCTTCAAATAAAACTCTTCCATTTTTCGGAGGGGGGGGCGATTTAGAAAGCCCCAAAAAATCCACAAA
CAACAAAAATAAGAAAAAAA

Product: N-acetylneuraminic acid synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MDFILGTRKIGINHTPLVVAEIGINHNGSLEIAKLMVDAAKRVGIEVIKHQTHIIEDEMSISALKVIPGNSELSIYEIMK
KCALSKNDERELKEYTEKQGLIFLSTPFSRAAANFLEDLGVVGYKIGSGEMNNTPLLKHIANFKKPMIISTGMHDLESVK
ECINPIIDKVPIALLHTTNLYPTPFELVRLNAMLDLKNAFKVPVGLSDHTLNNNACKSAIALGASIVERHFTDTKDREGP
DIVCSMDEEEAKDLVKSAQEIFLMRGGSKTKIKEEQVTRDFAFATMVAIKRIKKGEKITESNAWVKRPGVKGILAKDYEK
TLGRVAKIDIGIDEHICDEMLENKE

Sequences:

>Translated_345_residues
MDFILGTRKIGINHTPLVVAEIGINHNGSLEIAKLMVDAAKRVGIEVIKHQTHIIEDEMSISALKVIPGNSELSIYEIMK
KCALSKNDERELKEYTEKQGLIFLSTPFSRAAANFLEDLGVVGYKIGSGEMNNTPLLKHIANFKKPMIISTGMHDLESVK
ECINPIIDKVPIALLHTTNLYPTPFELVRLNAMLDLKNAFKVPVGLSDHTLNNNACKSAIALGASIVERHFTDTKDREGP
DIVCSMDEEEAKDLVKSAQEIFLMRGGSKTKIKEEQVTRDFAFATMVAIKRIKKGEKITESNAWVKRPGVKGILAKDYEK
TLGRVAKIDIGIDEHICDEMLENKE
>Mature_345_residues
MDFILGTRKIGINHTPLVVAEIGINHNGSLEIAKLMVDAAKRVGIEVIKHQTHIIEDEMSISALKVIPGNSELSIYEIMK
KCALSKNDERELKEYTEKQGLIFLSTPFSRAAANFLEDLGVVGYKIGSGEMNNTPLLKHIANFKKPMIISTGMHDLESVK
ECINPIIDKVPIALLHTTNLYPTPFELVRLNAMLDLKNAFKVPVGLSDHTLNNNACKSAIALGASIVERHFTDTKDREGP
DIVCSMDEEEAKDLVKSAQEIFLMRGGSKTKIKEEQVTRDFAFATMVAIKRIKKGEKITESNAWVKRPGVKGILAKDYEK
TLGRVAKIDIGIDEHICDEMLENKE

Specific function: Unknown

COG id: COG2089

COG function: function code M; Sialic acid synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To B.subtilis spsE [H]

Homologues:

Organism=Homo sapiens, GI12056473, Length=343, Percent_Identity=30.0291545189504, Blast_Score=143, Evalue=2e-34,
Organism=Drosophila melanogaster, GI21357081, Length=349, Percent_Identity=30.6590257879656, Blast_Score=137, Evalue=1e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006190
- InterPro:   IPR013785
- InterPro:   IPR013132
- InterPro:   IPR013974 [H]

Pfam domain/function: PF03102 NeuB; PF08666 SAF [H]

EC number: NA

Molecular weight: Translated: 38352; Mature: 38352

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: PS50844 AFP_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFILGTRKIGINHTPLVVAEIGINHNGSLEIAKLMVDAAKRVGIEVIKHQTHIIEDEMS
CCCCCCCEEECCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
ISALKVIPGNSELSIYEIMKKCALSKNDERELKEYTEKQGLIFLSTPFSRAAANFLEDLG
CEEEEEECCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHC
VVGYKIGSGEMNNTPLLKHIANFKKPMIISTGMHDLESVKECINPIIDKVPIALLHTTNL
HHEEEECCCCCCCCHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHCCEEEEEECCC
YPTPFELVRLNAMLDLKNAFKVPVGLSDHTLNNNACKSAIALGASIVERHFTDTKDREGP
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCC
DIVCSMDEEEAKDLVKSAQEIFLMRGGSKTKIKEEQVTRDFAFATMVAIKRIKKGEKITE
CEEEECCHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
SNAWVKRPGVKGILAKDYEKTLGRVAKIDIGIDEHICDEMLENKE
CCCEEECCCCCCHHHHHHHHHHHHEEEEECCCHHHHHHHHHHCCC
>Mature Secondary Structure
MDFILGTRKIGINHTPLVVAEIGINHNGSLEIAKLMVDAAKRVGIEVIKHQTHIIEDEMS
CCCCCCCEEECCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
ISALKVIPGNSELSIYEIMKKCALSKNDERELKEYTEKQGLIFLSTPFSRAAANFLEDLG
CEEEEEECCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHC
VVGYKIGSGEMNNTPLLKHIANFKKPMIISTGMHDLESVKECINPIIDKVPIALLHTTNL
HHEEEECCCCCCCCHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHCCEEEEEECCC
YPTPFELVRLNAMLDLKNAFKVPVGLSDHTLNNNACKSAIALGASIVERHFTDTKDREGP
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCC
DIVCSMDEEEAKDLVKSAQEIFLMRGGSKTKIKEEQVTRDFAFATMVAIKRIKKGEKITE
CEEEECCHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
SNAWVKRPGVKGILAKDYEKTLGRVAKIDIGIDEHICDEMLENKE
CCCEEECCCCCCHHHHHHHHHHHHEEEEECCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]