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The map label for this gene is ruvA

Identifier: 109947771

GI number: 109947771

Start: 1079584

End: 1080135

Strand: Reverse

Name: ruvA

Synonym: Hac_1248

Alternate gene names: 109947771

Gene position: 1080135-1079584 (Counterclockwise)

Preceding gene: 109947772

Following gene: 109947765

Centisome position: 69.51

GC content: 38.41

Gene sequence:

>552_bases
ATGACAGTGGGTTTAATAGGGGTCGTGGAAAAAATTTCCGCTTTAGAAGTGCATATAGAAGTGCAAGGCGTTGTTTATGG
GGTGCAAGTTTCTATGCGAACGGCGAGTATGCTTCAAACGGGCCAAAAAGCGCGTTTGAAAATCTTGCAAGTGATTAAAG
AAGACGCTCATCTTTTATATGGGTTTTTAGAAGAGAGCGAAAAAATCCTTTTTGAAAGGCTTTTAAAAATCAATGGGGTA
GGGGGGCGTATCGCATTAGCCATTCTTTCAAGCTTTTCACCGAATGAATTTGAAAATATTATCGCTACTAAAGAAGTCAA
AAGACTCCAGCAAGTTCCAGGCATTGGGAAAAAGCTCGCTGATAAGATCATGGTGGATTTGATTGGTTTTTTCATTCAAG
ATGAAACTAAACCTGTACATAATGAAGCCTTTTTAGCTTTAGAGAGTTTGGGCTTTAAAAGTGCAGAAATTAATCCCATT
TTAAAAAAGCTCAAACCTAATCTCAGCGTAGAAGAAGCGATTAAAGAAGCCTTGCAACAACTACGCTCTTAA

Upstream 100 bases:

>100_bases
AAGCCATAATGAAAGCGTGGATGTGATCTATGAAGACCATAAAATCAAAAAAATTCCTAAAAAGCGCTAAAAAAGGCTAA
ATGACAAGAAAGAGACAAAA

Downstream 100 bases:

>100_bases
AAAAATGATAAAATGCGGAATGGATTTTTTTAAATCTTATAAAAATAAAAATAGGTTTTAGTGGCAGGGTTTTAAACCTA
AAACACCCATCCGTAATTAA

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 183; Mature: 182

Protein sequence:

>183_residues
MTVGLIGVVEKISALEVHIEVQGVVYGVQVSMRTASMLQTGQKARLKILQVIKEDAHLLYGFLEESEKILFERLLKINGV
GGRIALAILSSFSPNEFENIIATKEVKRLQQVPGIGKKLADKIMVDLIGFFIQDETKPVHNEAFLALESLGFKSAEINPI
LKKLKPNLSVEEAIKEALQQLRS

Sequences:

>Translated_183_residues
MTVGLIGVVEKISALEVHIEVQGVVYGVQVSMRTASMLQTGQKARLKILQVIKEDAHLLYGFLEESEKILFERLLKINGV
GGRIALAILSSFSPNEFENIIATKEVKRLQQVPGIGKKLADKIMVDLIGFFIQDETKPVHNEAFLALESLGFKSAEINPI
LKKLKPNLSVEEAIKEALQQLRS
>Mature_182_residues
TVGLIGVVEKISALEVHIEVQGVVYGVQVSMRTASMLQTGQKARLKILQVIKEDAHLLYGFLEESEKILFERLLKINGVG
GRIALAILSSFSPNEFENIIATKEVKRLQQVPGIGKKLADKIMVDLIGFFIQDETKPVHNEAFLALESLGFKSAEINPIL
KKLKPNLSVEEAIKEALQQLRS

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family

Homologues:

Organism=Escherichia coli, GI1788168, Length=193, Percent_Identity=36.7875647668394, Blast_Score=102, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVA_HELAH (Q17WH6)

Other databases:

- EMBL:   AM260522
- RefSeq:   YP_664999.1
- ProteinModelPortal:   Q17WH6
- SMR:   Q17WH6
- STRING:   Q17WH6
- GeneID:   4177160
- GenomeReviews:   AM260522_GR
- KEGG:   hac:Hac_1248
- NMPDR:   fig|382638.8.peg.1213
- eggNOG:   COG0632
- HOGENOM:   HBG635309
- OMA:   IATKEVK
- ProtClustDB:   PRK00116
- BioCyc:   HACI382638:HAC_1248-MONOMER
- HAMAP:   MF_00031
- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00278
- TIGRFAMs:   TIGR00084

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N; SSF50249 Nucleic_acid_OB; SSF47781 RuvA_2_like; SSF46929 RuvA_C-like

EC number: =3.6.4.12

Molecular weight: Translated: 20278; Mature: 20147

Theoretical pI: Translated: 8.91; Mature: 8.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVGLIGVVEKISALEVHIEVQGVVYGVQVSMRTASMLQTGQKARLKILQVIKEDAHLLY
CCCHHHHHHHHHHHHEEEEEEEEEEEEEHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
GFLEESEKILFERLLKINGVGGRIALAILSSFSPNEFENIIATKEVKRLQQVPGIGKKLA
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHH
DKIMVDLIGFFIQDETKPVHNEAFLALESLGFKSAEINPILKKLKPNLSVEEAIKEALQQ
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHH
LRS
HCC
>Mature Secondary Structure 
TVGLIGVVEKISALEVHIEVQGVVYGVQVSMRTASMLQTGQKARLKILQVIKEDAHLLY
CCHHHHHHHHHHHHEEEEEEEEEEEEEHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
GFLEESEKILFERLLKINGVGGRIALAILSSFSPNEFENIIATKEVKRLQQVPGIGKKLA
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHH
DKIMVDLIGFFIQDETKPVHNEAFLALESLGFKSAEINPILKKLKPNLSVEEAIKEALQQ
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHH
LRS
HCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA