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The map label for this gene is cpdB [H]

Identifier: 109947351

GI number: 109947351

Start: 684478

End: 686220

Strand: Reverse

Name: cpdB [H]

Synonym: Hac_0790

Alternate gene names: 109947351

Gene position: 686220-684478 (Counterclockwise)

Preceding gene: 109947352

Following gene: 109947350

Centisome position: 44.16

GC content: 36.09

Gene sequence:

>1743_bases
ATGAAAAGATTGACTTTAGCCATCTTTTTAACGCTGACGCTTTCGGTATTTGCAAAAGAAGTGAAATTGGTGTTTTTGGC
AACATCAGACATTCACGGCCGGCTTTTTTCGTATGATTATGCCGTTGGGGAACAAAAACCCAATAACGGCCTTACGAGAA
TTACGACTTTAATCAAAAAGCAAAGAGCTGAAAATAAAAATGTGATTTTGATTGATATTGGGGATTTGTTACAGGGTAAT
AGTGCAGAGTTGTTTAATCATGAGCCAATTCACCCATTAGTTAGAGCCGAAAATGATTTGAAATTTGATGTTCGTGTGCT
TGGCAATCACGAGTTTAATTTTAGCAAAAGTTTTTTGGAAAAGAATATTAAGGGGTTTAATGGCGATGTCGTGAATGCGA
ATATTATTAAAACTGCGGACAATAAGCCGTTTGTGAAGCCTTATGCGATTAAAAAAATTGATGGCGTGAGGGTAGCGATT
GTGGGGTATTTAGTACCGCATGTTCCAACTTGGGAGGCATCTACGCCTGAACATTTTGCAGGATTAAAGTTTTTGAGCGC
TGAAGAAGCATTAAAAAAGACTTTGAAAGAGTTAAACGGGAAGCATGACATTTTGATTGGTGCTTTTCATTTAGGACGAG
AAGATGAAAAAGGTGGTGATGGGATACCTGATTTAGCGAAAAAATTCCCGCAATTTGACATTATTTTTGCAGGACACGAA
CATGCGGTTTATAACACAAAAATTGGAAAAGTGCATACAATTGAGCCTGGAGCATATGGGGTTTATCTTGCAAAAGGGGT
TGTTGTATTTGACACAAAAACAAAGAAAAAAATGGTAACGACTGAAAATTTGCCCACAAAAGATGTGCCAGAAGATGAAG
AGTTGGCGAAAAAATATGAATATGTGGATAAAAAATCAAAAGAATATGCACAAGAAGTTGTCGGAGAAGTGACAAAAACC
TTTATTGAAAGACCTGACTTTATTACAGGAGAAGCGAAAATCACTACAATGCCAACCGCCACATTACAAGAAACACCTAT
TATAACATTGATTAACAAAGTGCAAAAATATTACGCAAAAGCAGATGTTTCAGCAGCAGCCTTATTCAATTTTGGTTCCA
ATTTGAAAAAAGGACCTTTCAAAAGGAAAGATGTTGCATTCATTTACAAATTCACCAACACGCTCATTGGAGTGAATATG
ATGGGTGAAAATCTATTAAAATACATGGAATGGTCATATAGATTTTACAATCAGTTGCAGCCAGGAGATTTGACAATCAG
TTTTGACGAAAATATTCGTGGCTATAATTTTGATATGTTTTCTGGCGTGAAATACCAAGTTGATGTTACAAAACCCACTG
GACAAAGGATTATCAATCCCACCATTAACGGGAAACCAATTGATCCAAAAGCAACATACAAATTAGCGATCAATAATTAC
CGATTCGGAACATTGTCGGCATTACAATTGATTACAGACGCTGATAGGTATTATGATTCTTATGATGAGTTGCAAGACGG
TGGGCAAATACGAGATTTGATTATCAAGTTCATCACTGAAGAAAAAGGTGGGAAAGTAACACCTGAATTGGAGCATAACT
GGGAAATCATAAACTACAATTTCAAGAATCCGTTGTTGAAAAAATTGGCAGAAAAATTAAAAGATGGGAGCATAAAAATC
CCTACTTCAAAAGATGGGAGGACTTTGAATGTCAAATCCATTAAGGAAAGTGAAGTTGAATAA

Upstream 100 bases:

>100_bases
GATTTTATTAAAAAGTCAATTTTGTGTGTTTTGAAAATGAAAATTTTGAAATTTATAGGAAAATATCAAAAGAGTGGGAT
CTACAAAAAGGAAAATTTTA

Downstream 100 bases:

>100_bases
GGAAATGAGAGAGTTTTTAAGCTCTCTATTTTGTCATTAAAGAAAATTGGTTTTGTAAGTAGAATGGTATTGAAGCGAAC
TTTTAATGATTTTCTTAATG

Product: 2',3'-cyclic-nucleotide 2'-phosphodiesterase

Products: NA

Alternate protein names: 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase; 5'-nucleotidase [H]

Number of amino acids: Translated: 580; Mature: 580

Protein sequence:

>580_residues
MKRLTLAIFLTLTLSVFAKEVKLVFLATSDIHGRLFSYDYAVGEQKPNNGLTRITTLIKKQRAENKNVILIDIGDLLQGN
SAELFNHEPIHPLVRAENDLKFDVRVLGNHEFNFSKSFLEKNIKGFNGDVVNANIIKTADNKPFVKPYAIKKIDGVRVAI
VGYLVPHVPTWEASTPEHFAGLKFLSAEEALKKTLKELNGKHDILIGAFHLGREDEKGGDGIPDLAKKFPQFDIIFAGHE
HAVYNTKIGKVHTIEPGAYGVYLAKGVVVFDTKTKKKMVTTENLPTKDVPEDEELAKKYEYVDKKSKEYAQEVVGEVTKT
FIERPDFITGEAKITTMPTATLQETPIITLINKVQKYYAKADVSAAALFNFGSNLKKGPFKRKDVAFIYKFTNTLIGVNM
MGENLLKYMEWSYRFYNQLQPGDLTISFDENIRGYNFDMFSGVKYQVDVTKPTGQRIINPTINGKPIDPKATYKLAINNY
RFGTLSALQLITDADRYYDSYDELQDGGQIRDLIIKFITEEKGGKVTPELEHNWEIINYNFKNPLLKKLAEKLKDGSIKI
PTSKDGRTLNVKSIKESEVE

Sequences:

>Translated_580_residues
MKRLTLAIFLTLTLSVFAKEVKLVFLATSDIHGRLFSYDYAVGEQKPNNGLTRITTLIKKQRAENKNVILIDIGDLLQGN
SAELFNHEPIHPLVRAENDLKFDVRVLGNHEFNFSKSFLEKNIKGFNGDVVNANIIKTADNKPFVKPYAIKKIDGVRVAI
VGYLVPHVPTWEASTPEHFAGLKFLSAEEALKKTLKELNGKHDILIGAFHLGREDEKGGDGIPDLAKKFPQFDIIFAGHE
HAVYNTKIGKVHTIEPGAYGVYLAKGVVVFDTKTKKKMVTTENLPTKDVPEDEELAKKYEYVDKKSKEYAQEVVGEVTKT
FIERPDFITGEAKITTMPTATLQETPIITLINKVQKYYAKADVSAAALFNFGSNLKKGPFKRKDVAFIYKFTNTLIGVNM
MGENLLKYMEWSYRFYNQLQPGDLTISFDENIRGYNFDMFSGVKYQVDVTKPTGQRIINPTINGKPIDPKATYKLAINNY
RFGTLSALQLITDADRYYDSYDELQDGGQIRDLIIKFITEEKGGKVTPELEHNWEIINYNFKNPLLKKLAEKLKDGSIKI
PTSKDGRTLNVKSIKESEVE
>Mature_580_residues
MKRLTLAIFLTLTLSVFAKEVKLVFLATSDIHGRLFSYDYAVGEQKPNNGLTRITTLIKKQRAENKNVILIDIGDLLQGN
SAELFNHEPIHPLVRAENDLKFDVRVLGNHEFNFSKSFLEKNIKGFNGDVVNANIIKTADNKPFVKPYAIKKIDGVRVAI
VGYLVPHVPTWEASTPEHFAGLKFLSAEEALKKTLKELNGKHDILIGAFHLGREDEKGGDGIPDLAKKFPQFDIIFAGHE
HAVYNTKIGKVHTIEPGAYGVYLAKGVVVFDTKTKKKMVTTENLPTKDVPEDEELAKKYEYVDKKSKEYAQEVVGEVTKT
FIERPDFITGEAKITTMPTATLQETPIITLINKVQKYYAKADVSAAALFNFGSNLKKGPFKRKDVAFIYKFTNTLIGVNM
MGENLLKYMEWSYRFYNQLQPGDLTISFDENIRGYNFDMFSGVKYQVDVTKPTGQRIINPTINGKPIDPKATYKLAINNY
RFGTLSALQLITDADRYYDSYDELQDGGQIRDLIIKFITEEKGGKVTPELEHNWEIINYNFKNPLLKKLAEKLKDGSIKI
PTSKDGRTLNVKSIKESEVE

Specific function: Catalyzes the release of inorganic phosphate from 2',3'- cyclic nucleotides through consecutive 2',3'-phosphodiesterase and 3'- (or 2') nucleotidase activities. Also possesses a 5'- nucleotidase activity. Does not catalyze the release of inorganic phospha

COG id: COG0737

COG function: function code F; 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases

Gene ontology:

Cell location: Secreted, cell wall; Peptidoglycan-anchor (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 5'-nucleotidase family [H]

Homologues:

Organism=Escherichia coli, GI1790658, Length=618, Percent_Identity=27.6699029126214, Blast_Score=194, Evalue=2e-50,
Organism=Escherichia coli, GI1786687, Length=528, Percent_Identity=22.9166666666667, Blast_Score=88, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24641187, Length=537, Percent_Identity=21.6014897579143, Blast_Score=74, Evalue=3e-13,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008334
- InterPro:   IPR006146
- InterPro:   IPR006179
- InterPro:   IPR019931
- InterPro:   IPR004843
- InterPro:   IPR001899 [H]

Pfam domain/function: PF02872 5_nucleotid_C; PF00149 Metallophos [H]

EC number: =3.1.3.6; =3.1.4.16; =3.1.3.5 [H]

Molecular weight: Translated: 65546; Mature: 65546

Theoretical pI: Translated: 9.37; Mature: 9.37

Prosite motif: PS00786 5_NUCLEOTIDASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRLTLAIFLTLTLSVFAKEVKLVFLATSDIHGRLFSYDYAVGEQKPNNGLTRITTLIKK
CCCEEEHHHHHHHHHHHHHEEEEEEEEECCCCCEEEEEEEECCCCCCCCCHHHHHHHHHH
QRAENKNVILIDIGDLLQGNSAELFNHEPIHPLVRAENDLKFDVRVLGNHEFNFSKSFLE
HHCCCCCEEEEECHHHHCCCCCCCCCCCCCCHHHCCCCCCEEEEEEECCCCCCCHHHHHH
KNIKGFNGDVVNANIIKTADNKPFVKPYAIKKIDGVRVAIVGYLVPHVPTWEASTPEHFA
HHCCCCCCCEEECEEEEECCCCCCCCCEEEEECCCEEEEEEEHHHCCCCCCCCCCCHHHH
GLKFLSAEEALKKTLKELNGKHDILIGAFHLGREDEKGGDGIPDLAKKFPQFDIIFAGHE
CCEEECHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCHHHHHHCCCEEEEEECCC
HAVYNTKIGKVHTIEPGAYGVYLAKGVVVFDTKTKKKMVTTENLPTKDVPEDEELAKKYE
CEEEECCCCEEEEECCCCCEEEEECCEEEEECCCCCEEEEECCCCCCCCCCHHHHHHHHH
YVDKKSKEYAQEVVGEVTKTFIERPDFITGEAKITTMPTATLQETPIITLINKVQKYYAK
HHHHHHHHHHHHHHHHHHHHHHCCCCEEECCEEEEECCCCCCCCCCHHHHHHHHHHHHHH
ADVSAAALFNFGSNLKKGPFKRKDVAFIYKFTNTLIGVNMMGENLLKYMEWSYRFYNQLQ
CCCHHHHHHHCCCCCCCCCCCCCCEEEEEEEHHHEEEEHHHHHHHHHHHHHHHHHHCCCC
PGDLTISFDENIRGYNFDMFSGVKYQVDVTKPTGQRIINPTINGKPIDPKATYKLAINNY
CCCEEEEECCCCCCCCEEHCCCEEEEEEECCCCCCEEECCCCCCCCCCCCCEEEEEECCC
RFGTLSALQLITDADRYYDSYDELQDGGQIRDLIIKFITEEKGGKVTPELEHNWEIINYN
CCCHHHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEE
FKNPLLKKLAEKLKDGSIKIPTSKDGRTLNVKSIKESEVE
CCCHHHHHHHHHHCCCCEECCCCCCCCEEEECCCCCCCCC
>Mature Secondary Structure
MKRLTLAIFLTLTLSVFAKEVKLVFLATSDIHGRLFSYDYAVGEQKPNNGLTRITTLIKK
CCCEEEHHHHHHHHHHHHHEEEEEEEEECCCCCEEEEEEEECCCCCCCCCHHHHHHHHHH
QRAENKNVILIDIGDLLQGNSAELFNHEPIHPLVRAENDLKFDVRVLGNHEFNFSKSFLE
HHCCCCCEEEEECHHHHCCCCCCCCCCCCCCHHHCCCCCCEEEEEEECCCCCCCHHHHHH
KNIKGFNGDVVNANIIKTADNKPFVKPYAIKKIDGVRVAIVGYLVPHVPTWEASTPEHFA
HHCCCCCCCEEECEEEEECCCCCCCCCEEEEECCCEEEEEEEHHHCCCCCCCCCCCHHHH
GLKFLSAEEALKKTLKELNGKHDILIGAFHLGREDEKGGDGIPDLAKKFPQFDIIFAGHE
CCEEECHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCHHHHHHCCCEEEEEECCC
HAVYNTKIGKVHTIEPGAYGVYLAKGVVVFDTKTKKKMVTTENLPTKDVPEDEELAKKYE
CEEEECCCCEEEEECCCCCEEEEECCEEEEECCCCCEEEEECCCCCCCCCCHHHHHHHHH
YVDKKSKEYAQEVVGEVTKTFIERPDFITGEAKITTMPTATLQETPIITLINKVQKYYAK
HHHHHHHHHHHHHHHHHHHHHHCCCCEEECCEEEEECCCCCCCCCCHHHHHHHHHHHHHH
ADVSAAALFNFGSNLKKGPFKRKDVAFIYKFTNTLIGVNMMGENLLKYMEWSYRFYNQLQ
CCCHHHHHHHCCCCCCCCCCCCCCEEEEEEEHHHEEEEHHHHHHHHHHHHHHHHHHCCCC
PGDLTISFDENIRGYNFDMFSGVKYQVDVTKPTGQRIINPTINGKPIDPKATYKLAINNY
CCCEEEEECCCCCCCCEEHCCCEEEEEEECCCCCCEEECCCCCCCCCCCCCEEEEEECCC
RFGTLSALQLITDADRYYDSYDELQDGGQIRDLIIKFITEEKGGKVTPELEHNWEIINYN
CCCHHHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEE
FKNPLLKKLAEKLKDGSIKIPTSKDGRTLNVKSIKESEVE
CCCHHHHHHHHHHCCCCEECCCCCCCCEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969503; 9384377 [H]