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The map label for this gene is accA

Identifier: 109947339

GI number: 109947339

Start: 673769

End: 674710

Strand: Reverse

Name: accA

Synonym: Hac_0778

Alternate gene names: 109947339

Gene position: 674710-673769 (Counterclockwise)

Preceding gene: 109947340

Following gene: 109947335

Centisome position: 43.42

GC content: 39.07

Gene sequence:

>942_bases
ATGGCCATTTATTTAGATTTTGAAAATCATATTAAAGAGATTCAAAATGAAATTGAATTAGCCCTCATTAGAGGCGATGA
GGACGCTAAAGAAATCTTAGAAAAAAGATTGGATAAGGAAGTTAAAACCATTTACTCCAATCTCACTGATTTTCAAAAAC
TCCAGTTAGCAAGACACCCTGATAGACCCTACGCTATGGATTACATTGATTTGATCTTAAAAGATAAGTATGAAGTCTTT
GGGGATAGACATTACAATGATGATAAAGCGATCGTGTGTTTTATAGGGAAAATTGATAATATCCCAGTTGTGGTGATCGG
AGAAGAAAAAGGCAGAGGGACTAAAAACAAACTTTTAAGAAATTTTGGCATGCCCAATCCTTGCGGCTATCGTAAAGCTT
TGAAAATGGCAAAGTTTGCTGAAAAGTTTAATTTGCCTATCTTAATGCTTGTAGATACGGCTGGAGCGTATCCAGGAATT
GGTGCAGAAGAAAGAGGCCAAAGCGAAGCGATCGCTAAAAATCTCCAAGAGTTTGCTTCCTTAAAAGTCCCTACTATTTC
TATTATTATCGGTGAAGGGGGTAGTGGTGGCGCGTTAGCGATTGCGGTTGCAGACAAGTTGGCGATGATGGAATATTCCA
TTTTTAGCGTTATATCCCCAGAAGGTTGTGCGGCGATCCTTTGGGATGATCCTAGCAAGACTGAAGTGGCTATTAAAGCG
ATGAAAATCACGCCTAGAGACTTAAAAGAAGCAGGGCTTATTGATGATATTATCCTAGAGCCTAGCAAGGGGGCTCATAG
AAACAAAATCTCAGCGGCTAATACAATCAAAGAGTATTTTTTAGACACTCTAAGGACTATCCAACAAGACCCTCATTTCC
TTGACAACCGCTATAAAAAATTGATGTCGCTTGGTTCGTTTGTGGAAAGCATGCCACACTAA

Upstream 100 bases:

>100_bases
AGCAAGTGAATGCGGTGATGAGCAACTCATTTGGTTTTGGTGGCACTAATGGTGTTGTGATTTTCAAAAAAGTCTAGTTT
TACAAAGTCTAGGATTTTGA

Downstream 100 bases:

>100_bases
AAAAAGGGATTTTAAATACAAGGGTCAAAATAACTTAAGCTCTAAAAAAGAGCTTTAAGTTACTATAAACATAGTTTTAA
GTGAATGTGTGGTTCGTTTA

Product: acetyl-CoA carboxylase carboxyltransferase subunit alpha

Products: NA

Alternate protein names: ACCase subunit alpha; Acetyl-CoA carboxylase carboxyltransferase subunit alpha

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MAIYLDFENHIKEIQNEIELALIRGDEDAKEILEKRLDKEVKTIYSNLTDFQKLQLARHPDRPYAMDYIDLILKDKYEVF
GDRHYNDDKAIVCFIGKIDNIPVVVIGEEKGRGTKNKLLRNFGMPNPCGYRKALKMAKFAEKFNLPILMLVDTAGAYPGI
GAEERGQSEAIAKNLQEFASLKVPTISIIIGEGGSGGALAIAVADKLAMMEYSIFSVISPEGCAAILWDDPSKTEVAIKA
MKITPRDLKEAGLIDDIILEPSKGAHRNKISAANTIKEYFLDTLRTIQQDPHFLDNRYKKLMSLGSFVESMPH

Sequences:

>Translated_313_residues
MAIYLDFENHIKEIQNEIELALIRGDEDAKEILEKRLDKEVKTIYSNLTDFQKLQLARHPDRPYAMDYIDLILKDKYEVF
GDRHYNDDKAIVCFIGKIDNIPVVVIGEEKGRGTKNKLLRNFGMPNPCGYRKALKMAKFAEKFNLPILMLVDTAGAYPGI
GAEERGQSEAIAKNLQEFASLKVPTISIIIGEGGSGGALAIAVADKLAMMEYSIFSVISPEGCAAILWDDPSKTEVAIKA
MKITPRDLKEAGLIDDIILEPSKGAHRNKISAANTIKEYFLDTLRTIQQDPHFLDNRYKKLMSLGSFVESMPH
>Mature_312_residues
AIYLDFENHIKEIQNEIELALIRGDEDAKEILEKRLDKEVKTIYSNLTDFQKLQLARHPDRPYAMDYIDLILKDKYEVFG
DRHYNDDKAIVCFIGKIDNIPVVVIGEEKGRGTKNKLLRNFGMPNPCGYRKALKMAKFAEKFNLPILMLVDTAGAYPGIG
AEERGQSEAIAKNLQEFASLKVPTISIIIGEGGSGGALAIAVADKLAMMEYSIFSVISPEGCAAILWDDPSKTEVAIKAM
KITPRDLKEAGLIDDIILEPSKGAHRNKISAANTIKEYFLDTLRTIQQDPHFLDNRYKKLMSLGSFVESMPH

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-Co

COG id: COG0825

COG function: function code I; Acetyl-CoA carboxylase alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccA family

Homologues:

Organism=Escherichia coli, GI1786382, Length=317, Percent_Identity=49.211356466877, Blast_Score=295, Evalue=3e-81,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACCA_HELAH (Q17XQ8)

Other databases:

- EMBL:   AM260522
- RefSeq:   YP_664567.1
- ProteinModelPortal:   Q17XQ8
- SMR:   Q17XQ8
- STRING:   Q17XQ8
- GeneID:   4177690
- GenomeReviews:   AM260522_GR
- KEGG:   hac:Hac_0778
- NMPDR:   fig|382638.8.peg.752
- eggNOG:   COG0825
- HOGENOM:   HBG286557
- OMA:   QLTKDIY
- PhylomeDB:   Q17XQ8
- ProtClustDB:   PRK05724
- BioCyc:   HACI382638:HAC_0778-MONOMER
- HAMAP:   MF_00823
- InterPro:   IPR001095
- InterPro:   IPR011763
- PANTHER:   PTHR22855:SF3
- PRINTS:   PR01069
- TIGRFAMs:   TIGR00513

Pfam domain/function: PF03255 ACCA

EC number: =6.4.1.2

Molecular weight: Translated: 35067; Mature: 34936

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIYLDFENHIKEIQNEIELALIRGDEDAKEILEKRLDKEVKTIYSNLTDFQKLQLARHP
CEEEEEHHHHHHHHHHHHEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DRPYAMDYIDLILKDKYEVFGDRHYNDDKAIVCFIGKIDNIPVVVIGEEKGRGTKNKLLR
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCEEEEECCCCCCHHHHHHH
NFGMPNPCGYRKALKMAKFAEKFNLPILMLVDTAGAYPGIGAEERGQSEAIAKNLQEFAS
HCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHH
LKVPTISIIIGEGGSGGALAIAVADKLAMMEYSIFSVISPEGCAAILWDDPSKTEVAIKA
CCCCEEEEEEECCCCCCEEEEEHHHHHHHHHHHHHHEECCCCCEEEEECCCCCCEEEEEE
MKITPRDLKEAGLIDDIILEPSKGAHRNKISAANTIKEYFLDTLRTIQQDPHFLDNRYKK
EECCHHHHHHCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
LMSLGSFVESMPH
HHHHHHHHHHCCC
>Mature Secondary Structure 
AIYLDFENHIKEIQNEIELALIRGDEDAKEILEKRLDKEVKTIYSNLTDFQKLQLARHP
EEEEEHHHHHHHHHHHHEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DRPYAMDYIDLILKDKYEVFGDRHYNDDKAIVCFIGKIDNIPVVVIGEEKGRGTKNKLLR
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCEEEEECCCCCCHHHHHHH
NFGMPNPCGYRKALKMAKFAEKFNLPILMLVDTAGAYPGIGAEERGQSEAIAKNLQEFAS
HCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHH
LKVPTISIIIGEGGSGGALAIAVADKLAMMEYSIFSVISPEGCAAILWDDPSKTEVAIKA
CCCCEEEEEEECCCCCCEEEEEHHHHHHHHHHHHHHEECCCCCEEEEECCCCCCEEEEEE
MKITPRDLKEAGLIDDIILEPSKGAHRNKISAANTIKEYFLDTLRTIQQDPHFLDNRYKK
EECCHHHHHHCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
LMSLGSFVESMPH
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA