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The map label for this gene is mdaB [H]

Identifier: 109947311

GI number: 109947311

Start: 651902

End: 652486

Strand: Reverse

Name: mdaB [H]

Synonym: Hac_0742

Alternate gene names: 109947311

Gene position: 652486-651902 (Counterclockwise)

Preceding gene: 109947317

Following gene: 109947310

Centisome position: 41.99

GC content: 41.2

Gene sequence:

>585_bases
ATGAAAAAAATACTCATCATTAATGGAGCCAAAGCGTTTGGGCATTCTAATGGGAAACTCAATGAAACCTTGACCCACCA
TGCAAAAAAGACTCTAGAATCTTTAGGGATAGAAGTGGATACAACGATCGTGGATCAAGGCTATGAAACCCATCAAGAAG
TGGAAAAAATCCTTCACGCTGATGCGGCTATTTGGCAAATGCCCGGCTGGTGGATGGGAGAGCCTTGGATTGTGAAAAAA
TACATTGATGAGGTTTTTACTTCAGGGCGTGGGAAGCTTTATGCTAGCGATGGCAGAGATTCGCAAGATCCTACCAAAAA
CTATGGGAAAGGAGGCTTGATGCAAGGCAAAAAATACATGTTAAGTTTGACCTGGAATGCCCCTATTGAAGCCTTTAATG
ACCCTAATGAATTTTTTGAAGGAATAGGCGTGGATGGCTTGTATTTGCATTTGCATAAGGCGTTCCAATTTTTAGGACTT
TCAGCATTGCCCACTTTTATTTGTAATGATGTGATGAAAAACCCCCAAGTAGAGCAATATCTTAGCTCTCTCACTACGCA
CTTGCATCAAGTTTTTGGCAAATAG

Upstream 100 bases:

>100_bases
TGCATTATCTTAACACAATAAAAATAGAATGGCTTTAGTATTGGTTTATTTTGGATAGAATACCCCCTATTATTAAAAAT
TTTATTAAAAAAGAAACAAA

Downstream 100 bases:

>100_bases
TCTTAAAATAAGGATTTTTAAATCCTTGTTGCAACGCTATTTTAAAATGGTATGATTGATTAAAAATTATGGGAGTTTAG
TTTGCGTGTTTTTATCATTT

Product: modulator of drug activity B

Products: NADP; a reduced quinone; reduced acceptor [C]

Alternate protein names: NA

Number of amino acids: Translated: 194; Mature: 194

Protein sequence:

>194_residues
MKKILIINGAKAFGHSNGKLNETLTHHAKKTLESLGIEVDTTIVDQGYETHQEVEKILHADAAIWQMPGWWMGEPWIVKK
YIDEVFTSGRGKLYASDGRDSQDPTKNYGKGGLMQGKKYMLSLTWNAPIEAFNDPNEFFEGIGVDGLYLHLHKAFQFLGL
SALPTFICNDVMKNPQVEQYLSSLTTHLHQVFGK

Sequences:

>Translated_194_residues
MKKILIINGAKAFGHSNGKLNETLTHHAKKTLESLGIEVDTTIVDQGYETHQEVEKILHADAAIWQMPGWWMGEPWIVKK
YIDEVFTSGRGKLYASDGRDSQDPTKNYGKGGLMQGKKYMLSLTWNAPIEAFNDPNEFFEGIGVDGLYLHLHKAFQFLGL
SALPTFICNDVMKNPQVEQYLSSLTTHLHQVFGK
>Mature_194_residues
MKKILIINGAKAFGHSNGKLNETLTHHAKKTLESLGIEVDTTIVDQGYETHQEVEKILHADAAIWQMPGWWMGEPWIVKK
YIDEVFTSGRGKLYASDGRDSQDPTKNYGKGGLMQGKKYMLSLTWNAPIEAFNDPNEFFEGIGVDGLYLHLHKAFQFLGL
SALPTFICNDVMKNPQVEQYLSSLTTHLHQVFGK

Specific function: Unknown

COG id: COG2249

COG function: function code R; Putative NADPH-quinone reductase (modulator of drug activity B)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli madB and S.pombe SPAC5H10.05c [H]

Homologues:

Organism=Escherichia coli, GI1789406, Length=193, Percent_Identity=61.6580310880829, Blast_Score=253, Evalue=4e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003680 [H]

Pfam domain/function: PF02525 Flavodoxin_2 [H]

EC number: NA

Molecular weight: Translated: 21855; Mature: 21855

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKILIINGAKAFGHSNGKLNETLTHHAKKTLESLGIEVDTTIVDQGYETHQEVEKILHA
CCEEEEEECCHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHHHHHHHHHH
DAAIWQMPGWWMGEPWIVKKYIDEVFTSGRGKLYASDGRDSQDPTKNYGKGGLMQGKKYM
HHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHCCCCCCCCCCEEE
LSLTWNAPIEAFNDPNEFFEGIGVDGLYLHLHKAFQFLGLSALPTFICNDVMKNPQVEQY
EEEEECCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCHHHH
LSSLTTHLHQVFGK
HHHHHHHHHHHHCC
>Mature Secondary Structure
MKKILIINGAKAFGHSNGKLNETLTHHAKKTLESLGIEVDTTIVDQGYETHQEVEKILHA
CCEEEEEECCHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHHHHHHHHHH
DAAIWQMPGWWMGEPWIVKKYIDEVFTSGRGKLYASDGRDSQDPTKNYGKGGLMQGKKYM
HHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHCCCCCCCCCCEEE
LSLTWNAPIEAFNDPNEFFEGIGVDGLYLHLHKAFQFLGLSALPTFICNDVMKNPQVEQY
EEEEECCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCHHHH
LSSLTTHLHQVFGK
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADPH; a quinone; Acceptor; NADPH [C]

Specific reaction: NADPH + a quinone = NADP + a reduced quinone Acceptor + NADPH = reduced acceptor + NADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]