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The map label for this gene is sotB

Identifier: 109947000

GI number: 109947000

Start: 336529

End: 337704

Strand: Direct

Name: sotB

Synonym: Hac_0393

Alternate gene names: 109947000

Gene position: 336529-337704 (Clockwise)

Preceding gene: 109946996

Following gene: 109947001

Centisome position: 21.66

GC content: 43.03

Gene sequence:

>1176_bases
ATGATGATAACCAAACAATCGTATAAAAAACTCGCCTTAATGCGGGTTTTTGTGTTTTCACTTTCGGCGTTTATTTTCAA
CACCACGGAGTTTGTCCCTATTGCACTTTTATCAGATATTGCAAAAAGTTTTGAAATGGAGAGCGCGAGCGTGGGGCTTA
TGATCACACTTTATGCGTGGATCGTGTCTCTTGGCTCATTGCCTTTGATGCTGCTTAGTGCTAAAATTGAAAGGAAACGC
TTGCTGCTTTTTCTTTTTGGTCTTTTTATTGTCAGCCATATCCTTTCAGTGGTGGCGTGGGATTTTTGGGTGTTATTAAT
TTCGCGCATGGGCATCGCTTTGGCTCATTCTGTTTTTTGGTCTATCACGGCTTCTTTAGTCATTCGTGTCGCACCCATTG
GCAGGAAACAACAAGCTTTAGGGTTATTAGCGTTAGGGAGTTCGCTAGCGATGATTTTAGGGTTACCGCTTGGGAGGATC
ATTGGGCAAATGTTAGATTGGCGCTCCACTTTTGGCATGATTGGGGGCGTTGCTTTGTTGGTAGCATTGCTTATGTATAG
GCTGCTCCCATCTTTACCGAGTAGAAACGCCGGTACTTTATCTAGCCTTCCTGTGTTAATGAAACGCCCGCTTTTAGTGG
GGATTTATTTGCTTGTGATTTTGGCTATTTCTGGGCATTTCACCACTTATAGTTATATTGAGCCTTTTATCATTCAAATC
AGCCAATTTTCCCCTGAAGTGGCGACGCTGATGCTGTTTGTGTTTGGGCTAGCGGGTGTTATGGGGAGCTTTTTATTCGG
TCGTTTTTATGAGAAAAACCCTAAAAAATTCATCGCTTGCGCCATTATTTTAGTCCTTTGCCCGCAACTTCTACTTTTTT
CATTCAAGCATTTAGAGTGGGTAATTTTCTTGCAAATTTTCTTATGGGGGATTGGGATCACTTCGCTTGGGATTTCCTTG
CAAATGAGGGTGTTGCAACTTGCACCCAATGCCACGGATGTTGCAAGCGCGATTTTTTCAGGGAGCTATAATGTGGGGAT
TGGATCAGGAGCGTTGTTTGGCAGTATTGTGATCCACCAATTGGGGTTAGGGTATATTGGCTTTGTGGGTGGGGCACTAG
GTTTGTTGGCGCTATTTTGGTTTAATTTCATCACGATCAAATTTGGGGCAAAATAG

Upstream 100 bases:

>100_bases
TGGTAACAATTTTAGGGGGTTTAATCGCAAGCGGTTAAATTTTTTATCTTATAATGGGCGTTTCAAATGGGAGATTTAAC
CACCTTAATTTTAAGATTGA

Downstream 100 bases:

>100_bases
ATGAAAATCTCTCCTTAAATTGAGCGGTATTTAACTGATAAATTGTCTCTTTCTTTATGTTAAAATAACAAAATTTGTCA
CATTTTTTAAACAACAAGCG

Product: sugar efflux transporter

Products: arabinose [Periplasm]; Proton [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MMITKQSYKKLALMRVFVFSLSAFIFNTTEFVPIALLSDIAKSFEMESASVGLMITLYAWIVSLGSLPLMLLSAKIERKR
LLLFLFGLFIVSHILSVVAWDFWVLLISRMGIALAHSVFWSITASLVIRVAPIGRKQQALGLLALGSSLAMILGLPLGRI
IGQMLDWRSTFGMIGGVALLVALLMYRLLPSLPSRNAGTLSSLPVLMKRPLLVGIYLLVILAISGHFTTYSYIEPFIIQI
SQFSPEVATLMLFVFGLAGVMGSFLFGRFYEKNPKKFIACAIILVLCPQLLLFSFKHLEWVIFLQIFLWGIGITSLGISL
QMRVLQLAPNATDVASAIFSGSYNVGIGSGALFGSIVIHQLGLGYIGFVGGALGLLALFWFNFITIKFGAK

Sequences:

>Translated_391_residues
MMITKQSYKKLALMRVFVFSLSAFIFNTTEFVPIALLSDIAKSFEMESASVGLMITLYAWIVSLGSLPLMLLSAKIERKR
LLLFLFGLFIVSHILSVVAWDFWVLLISRMGIALAHSVFWSITASLVIRVAPIGRKQQALGLLALGSSLAMILGLPLGRI
IGQMLDWRSTFGMIGGVALLVALLMYRLLPSLPSRNAGTLSSLPVLMKRPLLVGIYLLVILAISGHFTTYSYIEPFIIQI
SQFSPEVATLMLFVFGLAGVMGSFLFGRFYEKNPKKFIACAIILVLCPQLLLFSFKHLEWVIFLQIFLWGIGITSLGISL
QMRVLQLAPNATDVASAIFSGSYNVGIGSGALFGSIVIHQLGLGYIGFVGGALGLLALFWFNFITIKFGAK
>Mature_391_residues
MMITKQSYKKLALMRVFVFSLSAFIFNTTEFVPIALLSDIAKSFEMESASVGLMITLYAWIVSLGSLPLMLLSAKIERKR
LLLFLFGLFIVSHILSVVAWDFWVLLISRMGIALAHSVFWSITASLVIRVAPIGRKQQALGLLALGSSLAMILGLPLGRI
IGQMLDWRSTFGMIGGVALLVALLMYRLLPSLPSRNAGTLSSLPVLMKRPLLVGIYLLVILAISGHFTTYSYIEPFIIQI
SQFSPEVATLMLFVFGLAGVMGSFLFGRFYEKNPKKFIACAIILVLCPQLLLFSFKHLEWVIFLQIFLWGIGITSLGISL
QMRVLQLAPNATDVASAIFSGSYNVGIGSGALFGSIVIHQLGLGYIGFVGGALGLLALFWFNFITIKFGAK

Specific function: Involved in the efflux of sugars. The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites

COG id: COG2814

COG function: function code G; Arabinose efflux permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. SotB (TC 2.A.1.2) family

Homologues:

Organism=Escherichia coli, GI1787808, Length=379, Percent_Identity=49.6042216358839, Blast_Score=339, Evalue=2e-94,
Organism=Escherichia coli, GI1787947, Length=343, Percent_Identity=28.2798833819242, Blast_Score=131, Evalue=6e-32,
Organism=Escherichia coli, GI1786595, Length=347, Percent_Identity=25.6484149855908, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI145693198, Length=334, Percent_Identity=23.6526946107784, Blast_Score=104, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SOTB_HELAH (Q17YP7)

Other databases:

- EMBL:   AM260522
- RefSeq:   YP_664228.1
- ProteinModelPortal:   Q17YP7
- STRING:   Q17YP7
- GeneID:   4177522
- GenomeReviews:   AM260522_GR
- KEGG:   hac:Hac_0393
- NMPDR:   fig|382638.8.peg.382
- eggNOG:   COG2814
- HOGENOM:   HBG732715
- OMA:   IASHILT
- PhylomeDB:   Q17YP7
- ProtClustDB:   PRK03545
- BioCyc:   HACI382638:HAC_0393-MONOMER
- HAMAP:   MF_00517
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196

Pfam domain/function: PF07690 MFS_1; SSF103473 MFS_gen_substrate_transporter

EC number: NA

Molecular weight: Translated: 42882; Mature: 42882

Theoretical pI: Translated: 10.57; Mature: 10.57

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x12c2e0a4)-; HASH(0x12d3b950)-; HASH(0x12d26b90)-; HASH(0x129968f4)-; HASH(0x11510c48)-; HASH(0x12d1c580)-; HASH(0x12996954)-; HASH(0x124ec8a0)-; HASH(0x1232ebec)-; HASH(0x12a5ed20)-; HASH(0x1227d644)-; HASH(0x12a10040)-;

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HCCHHHHHHHHHHHHHHHHHHHHHHHEECCH
>Mature Secondary Structure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HCCHHHHHHHHHHHHHHHHHHHHHHHEECCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: arabinose [Cytoplasm]; Proton [Periplasm] [C]

Specific reaction: arabinose [Cytoplasm] + Proton [Periplasm] = arabinose [Periplasm] + Proton [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA