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The map label for this gene is hcpD [H]

Identifier: 109946953

GI number: 109946953

Start: 290558

End: 291454

Strand: Direct

Name: hcpD [H]

Synonym: Hac_0343

Alternate gene names: 109946953

Gene position: 290558-291454 (Clockwise)

Preceding gene: 109946951

Following gene: 109946965

Centisome position: 18.7

GC content: 41.58

Gene sequence:

>897_bases
ATGATAAATAGTTGGACTAAAAAGTGGGCTTTTATTTTGTTTTTAATGGCAGGCTGTTTGGGTCATTTGATGGCTCGAAC
CGGTGAGGCGTACCTTAAAAAGGCTAATCAAGCCCTTAAGATGGGGCACCATCAAAAAGCGGTGGCGTTTTATAAGAGGA
GTTGTAATTTGAGGGTGGGGGTGAGTTGCACGAGTTTGGGCTCTATGTATGAAGATGGCGAAGGCGTGGATCAAGATATC
ACAAAAGCCGTTTTTTATTACAAAAGAGGGTGTAATTTGCACGATCGCCTCGCTTGCGCGAGTTTGGGCTCTATGTATGA
AGATGGCGACAGTGTGCAAAAAGACCTTTCAAAAGCCCTTTATTATTACAAAAGAGGGTGCCATTTAAAAGAGGGAGTGA
GTTGCGGGAGTTTAGGCTTTATGTATTTTAAGGGCGTTGGCGTGACACAGGATGATGTTAAGGCGCTTGCTTTAAGCAAA
CAGGCTTGCAATTTGAATTATGCGGTTAGCTGTAATTTAGCAGGCTATATGTATAGAAACGCCAAAGGCACAGAGCAGGA
TCTAAAAAAAGCCTTTATGAGTTTTAGAAGAGGTTGTCATCTAAAAAATGGGGCGAGTTGCACGAGTTTGGGCTACATGT
ATGAAACCGGTATTTATGTCAATCAAAGTGGGGAGCAGGCTTTGAGTCTTTATAAAAAGGGTTGCTCTTTAAAAGAGGGG
AGTGGTTGCCATAATGTCGCAGTGATGTATTTAAGCGGTAAGGGTGCTCCAAAAGATTTAGAGAAAGCCACTTCATTTTA
TGAAAAAGGGTGTTCTTTTGGCTTTAGCGGTAGCTGTAAAGCGTTAGAAATTATCCGCGACAACCCTGATATTTATTATT
ATAATGGGCATAAGTAA

Upstream 100 bases:

>100_bases
ATTTTTTTAATATTATACTATAATAGCCTATTAGATTGGAGTTTTACTAATTTTTCTTTGAGTGAGCGTGGAGCGTTTGC
TTATAGTTTTAAGGAACGAG

Downstream 100 bases:

>100_bases
AGCTTCTGAGAATAGATAGGGATTAAGTCTCTATCTATAACCATTGAGAATGCGATAAAAATCTAGAATTTAGGATTTAG
AACCGCTTTTATTGAGTCCT

Product: hypothetical protein

Products: NA

Alternate protein names: Cysteine-rich protein D; Penicillin-binding protein 4; PBP 4 [H]

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MINSWTKKWAFILFLMAGCLGHLMARTGEAYLKKANQALKMGHHQKAVAFYKRSCNLRVGVSCTSLGSMYEDGEGVDQDI
TKAVFYYKRGCNLHDRLACASLGSMYEDGDSVQKDLSKALYYYKRGCHLKEGVSCGSLGFMYFKGVGVTQDDVKALALSK
QACNLNYAVSCNLAGYMYRNAKGTEQDLKKAFMSFRRGCHLKNGASCTSLGYMYETGIYVNQSGEQALSLYKKGCSLKEG
SGCHNVAVMYLSGKGAPKDLEKATSFYEKGCSFGFSGSCKALEIIRDNPDIYYYNGHK

Sequences:

>Translated_298_residues
MINSWTKKWAFILFLMAGCLGHLMARTGEAYLKKANQALKMGHHQKAVAFYKRSCNLRVGVSCTSLGSMYEDGEGVDQDI
TKAVFYYKRGCNLHDRLACASLGSMYEDGDSVQKDLSKALYYYKRGCHLKEGVSCGSLGFMYFKGVGVTQDDVKALALSK
QACNLNYAVSCNLAGYMYRNAKGTEQDLKKAFMSFRRGCHLKNGASCTSLGYMYETGIYVNQSGEQALSLYKKGCSLKEG
SGCHNVAVMYLSGKGAPKDLEKATSFYEKGCSFGFSGSCKALEIIRDNPDIYYYNGHK
>Mature_298_residues
MINSWTKKWAFILFLMAGCLGHLMARTGEAYLKKANQALKMGHHQKAVAFYKRSCNLRVGVSCTSLGSMYEDGEGVDQDI
TKAVFYYKRGCNLHDRLACASLGSMYEDGDSVQKDLSKALYYYKRGCHLKEGVSCGSLGFMYFKGVGVTQDDVKALALSK
QACNLNYAVSCNLAGYMYRNAKGTEQDLKKAFMSFRRGCHLKNGASCTSLGYMYETGIYVNQSGEQALSLYKKGCSLKEG
SGCHNVAVMYLSGKGAPKDLEKATSFYEKGCSFGFSGSCKALEIIRDNPDIYYYNGHK

Specific function: May hydrolyze 6-aminopenicillinic acid and 7- aminocephalosporanic acid (ACA) derivatives. Binds to penicillin [H]

COG id: COG0790

COG function: function code R; FOG: TPR repeat, SEL1 subfamily

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 4 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI151301150, Length=176, Percent_Identity=29.5454545454545, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI87081769, Length=285, Percent_Identity=25.2631578947368, Blast_Score=86, Evalue=4e-18,
Organism=Drosophila melanogaster, GI21355295, Length=173, Percent_Identity=29.4797687861272, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006597
- InterPro:   IPR011990 [H]

Pfam domain/function: PF08238 Sel1 [H]

EC number: =3.5.2.6 [H]

Molecular weight: Translated: 32937; Mature: 32937

Theoretical pI: Translated: 8.99; Mature: 8.99

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
8.7 %Cys+Met (Translated Protein)
5.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
8.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINSWTKKWAFILFLMAGCLGHLMARTGEAYLKKANQALKMGHHQKAVAFYKRSCNLRVG
CCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCEEEE
VSCTSLGSMYEDGEGVDQDITKAVFYYKRGCNLHDRLACASLGSMYEDGDSVQKDLSKAL
CCHHHHCCHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHH
YYYKRGCHLKEGVSCGSLGFMYFKGVGVTQDDVKALALSKQACNLNYAVSCNLAGYMYRN
HHHHCCCCHHHCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCEEEEEC
AKGTEQDLKKAFMSFRRGCHLKNGASCTSLGYMYETGIYVNQSGEQALSLYKKGCSLKEG
CCCCHHHHHHHHHHHHHCCCCCCCCCHHHHCCEEECCEEEECCHHHHHHHHHHCCCCCCC
SGCHNVAVMYLSGKGAPKDLEKATSFYEKGCSFGFSGSCKALEIIRDNPDIYYYNGHK
CCCCEEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCEEEECCCC
>Mature Secondary Structure
MINSWTKKWAFILFLMAGCLGHLMARTGEAYLKKANQALKMGHHQKAVAFYKRSCNLRVG
CCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCEEEE
VSCTSLGSMYEDGEGVDQDITKAVFYYKRGCNLHDRLACASLGSMYEDGDSVQKDLSKAL
CCHHHHCCHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHH
YYYKRGCHLKEGVSCGSLGFMYFKGVGVTQDDVKALALSKQACNLNYAVSCNLAGYMYRN
HHHHCCCCHHHCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCEEEEEC
AKGTEQDLKKAFMSFRRGCHLKNGASCTSLGYMYETGIYVNQSGEQALSLYKKGCSLKEG
CCCCHHHHHHHHHHHHHCCCCCCCCCHHHHCCEEECCEEEECCHHHHHHHHHHCCCCCCC
SGCHNVAVMYLSGKGAPKDLEKATSFYEKGCSFGFSGSCKALEIIRDNPDIYYYNGHK
CCCCEEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9252185; 10438788 [H]