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The map label for this gene is secD [H]

Identifier: 109946904

GI number: 109946904

Start: 243054

End: 244634

Strand: Direct

Name: secD [H]

Synonym: Hac_0290

Alternate gene names: 109946904

Gene position: 243054-244634 (Clockwise)

Preceding gene: 109946903

Following gene: 109946905

Centisome position: 15.64

GC content: 42.69

Gene sequence:

>1581_bases
ATGAAACTTTTTAATTTTCGTTTGATCGTTTTTGTTTTCGCGCTTTTTTTTGGCGTAGGGTTTTCTGTGCCTTCTTTACT
AGAGACTAAAGGTCCTAAAATCACTTTAGGTTTGGATTTAAGGGGGGGGTTAAACATGCTTTTAGGGGTGCAAACCGATG
AGGCTTTAAAAAACAAATATTTAAGCCTAGCGTCCGCTTTAGAATACAACGCTAAAAAGCAAAACATCTTGCTTAAAGAC
ATTAAATCCAGTTTAGAAGGGGTTAGCTTTGAGCTTTTAGATGAAGATGAAGCGAAAAAATTAGACACGCTTTTAGTAGA
GTTGCAGGGTCATAGCCAGTTTGAGATCAAAAAAGAAGCGGAGTTTTATAGCGTGAAGCTCACCCCTTTAGAGCAAGAAG
AATTGCGTAAAAACACGATTTTGCAAGTCATAGGGGTTATCCGTAACCGCTTGGATCAATTTGGTTTGGCAGAGCCTGTG
GTTATCCAACAAGGCAGAGAAGAAATTTCGGTGCAATTACCTGGCATTAAGACTTTAGAAGAAGAACGGCGTGCTAAAGA
TTTGATTTCTAGATCCGCTCATTTGCAAATGATGGCAGTGGATGAAGAGCATAATAAAGATGCCATGACAATGACGGATT
TAGAGGCTCAAAAATTAGGCAGCGTGTTATTGTCTGATGTGGAAATGGGGGGTAAGATCTTACTCAAAGCGATCCCTATT
TTAGATGGCGAAATGCTTACAGATGCGAAAGTGGTGTATGACCAAAACAACCAGCCGGTGGTGAGTTTTACTTTGGATGC
GCAAGGGGCTAAGATTTTTGGGGATTTTTCAGGTGCGAATGTGGGCAAACGCATGGCAATTGTTTTGGACAATAAGGTCT
ATTCAGCCCCCGTGATCAGAGAGCGCATTGGGGGAGGGAGCGGGCAAATTAGTGGGAGTTTTAGCGTGGCTCAAGCGAGC
GATTTAGCGATCGCTTTAAGGAGTGGGGCGATGAAAGCACCCATTCAAGTTTTAGAAAAACGAATCGTGGGTCCGAGTTT
GGGGAAAGACAGCATTAAAACTTCCATTAACGCTCTAATAGGGGGCTTTATTTTGGTGTTAGGTTTTATGGTGTTGTATT
ACTCTATGGCTGGGGTGATCGCTTGCGTGGCGTTAGTGGTGAATCTTTTTTTGATCGTGGCGGTGATGGCGATTTTTGGA
GCGACGCTGACTTTACCTGGAATGGCAGGGATTGTTTTAACTGTGGGGATTGCCGTAGATGCTAATATCATTATTAATGA
GCGTATTAGAGAGGTGTTAAGGGAGGGCGAGAGTATCGCTAAAGCGATCCATTTAGGCTATATCAATGCAAGTCGGGCGA
TTTTTGATTCCAATATCACCTCCTTGATCGCTTCAGTGTTGTTATACGCTTATGGCACAGGAGCGATTAAAGGCTTTGCG
CTCACCACAGGCATTGGGATTTTAGCCTCTATTATCACCGCTATTATAGGCACGCAAGGGATTTATCAAGCCCTTTTGCC
TAAATTGACCCAAACCAAGAGCCTTTACTTTTGGTTTGGCGTGAAAAATAAAAGAGCTTAG

Upstream 100 bases:

>100_bases
TTTTTTTAGCGTGAAGCTCAGCGATGATTCTACGGCTAAACTTTCTAAAAACTATATAGCGTTCAAATTAGACGAAGAAG
TAGTGCCAAACAACAACTAA

Downstream 100 bases:

>100_bases
GAGTTTTTATGGAATTATTCAAACAAACTAGAATTTTAAGCTTCATGCGTTATTCCAATTATGGGGCGATTCTTTCAGCG
ATTTTGGTGCTTCTAGCGTT

Product: preprotein translocase subunit SecD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 526; Mature: 526

Protein sequence:

>526_residues
MKLFNFRLIVFVFALFFGVGFSVPSLLETKGPKITLGLDLRGGLNMLLGVQTDEALKNKYLSLASALEYNAKKQNILLKD
IKSSLEGVSFELLDEDEAKKLDTLLVELQGHSQFEIKKEAEFYSVKLTPLEQEELRKNTILQVIGVIRNRLDQFGLAEPV
VIQQGREEISVQLPGIKTLEEERRAKDLISRSAHLQMMAVDEEHNKDAMTMTDLEAQKLGSVLLSDVEMGGKILLKAIPI
LDGEMLTDAKVVYDQNNQPVVSFTLDAQGAKIFGDFSGANVGKRMAIVLDNKVYSAPVIRERIGGGSGQISGSFSVAQAS
DLAIALRSGAMKAPIQVLEKRIVGPSLGKDSIKTSINALIGGFILVLGFMVLYYSMAGVIACVALVVNLFLIVAVMAIFG
ATLTLPGMAGIVLTVGIAVDANIIINERIREVLREGESIAKAIHLGYINASRAIFDSNITSLIASVLLYAYGTGAIKGFA
LTTGIGILASIITAIIGTQGIYQALLPKLTQTKSLYFWFGVKNKRA

Sequences:

>Translated_526_residues
MKLFNFRLIVFVFALFFGVGFSVPSLLETKGPKITLGLDLRGGLNMLLGVQTDEALKNKYLSLASALEYNAKKQNILLKD
IKSSLEGVSFELLDEDEAKKLDTLLVELQGHSQFEIKKEAEFYSVKLTPLEQEELRKNTILQVIGVIRNRLDQFGLAEPV
VIQQGREEISVQLPGIKTLEEERRAKDLISRSAHLQMMAVDEEHNKDAMTMTDLEAQKLGSVLLSDVEMGGKILLKAIPI
LDGEMLTDAKVVYDQNNQPVVSFTLDAQGAKIFGDFSGANVGKRMAIVLDNKVYSAPVIRERIGGGSGQISGSFSVAQAS
DLAIALRSGAMKAPIQVLEKRIVGPSLGKDSIKTSINALIGGFILVLGFMVLYYSMAGVIACVALVVNLFLIVAVMAIFG
ATLTLPGMAGIVLTVGIAVDANIIINERIREVLREGESIAKAIHLGYINASRAIFDSNITSLIASVLLYAYGTGAIKGFA
LTTGIGILASIITAIIGTQGIYQALLPKLTQTKSLYFWFGVKNKRA
>Mature_526_residues
MKLFNFRLIVFVFALFFGVGFSVPSLLETKGPKITLGLDLRGGLNMLLGVQTDEALKNKYLSLASALEYNAKKQNILLKD
IKSSLEGVSFELLDEDEAKKLDTLLVELQGHSQFEIKKEAEFYSVKLTPLEQEELRKNTILQVIGVIRNRLDQFGLAEPV
VIQQGREEISVQLPGIKTLEEERRAKDLISRSAHLQMMAVDEEHNKDAMTMTDLEAQKLGSVLLSDVEMGGKILLKAIPI
LDGEMLTDAKVVYDQNNQPVVSFTLDAQGAKIFGDFSGANVGKRMAIVLDNKVYSAPVIRERIGGGSGQISGSFSVAQAS
DLAIALRSGAMKAPIQVLEKRIVGPSLGKDSIKTSINALIGGFILVLGFMVLYYSMAGVIACVALVVNLFLIVAVMAIFG
ATLTLPGMAGIVLTVGIAVDANIIINERIREVLREGESIAKAIHLGYINASRAIFDSNITSLIASVLLYAYGTGAIKGFA
LTTGIGILASIITAIIGTQGIYQALLPKLTQTKSLYFWFGVKNKRA

Specific function: Involved in protein export [H]

COG id: COG0342

COG function: function code U; Preprotein translocase subunit SecD

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secD/secF family. SecD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786609, Length=499, Percent_Identity=37.0741482965932, Blast_Score=290, Evalue=2e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001036
- InterPro:   IPR005791
- InterPro:   IPR022813
- InterPro:   IPR022646
- InterPro:   IPR022645 [H]

Pfam domain/function: PF07549 Sec_GG; PF02355 SecD_SecF [H]

EC number: NA

Molecular weight: Translated: 56959; Mature: 56959

Theoretical pI: Translated: 8.32; Mature: 8.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLFNFRLIVFVFALFFGVGFSVPSLLETKGPKITLGLDLRGGLNMLLGVQTDEALKNKY
CCEEHHHHHHHHHHHHHHCCCCCCHHHHCCCCEEEEEEECCCCCCEEEECCCHHHHHHHH
LSLASALEYNAKKQNILLKDIKSSLEGVSFELLDEDEAKKLDTLLVELQGHSQFEIKKEA
HHHHHHHHCCCHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHEEECCCCCEEEEECC
EFYSVKLTPLEQEELRKNTILQVIGVIRNRLDQFGLAEPVVIQQGREEISVQLPGIKTLE
EEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCEEEECCCCHHHH
EERRAKDLISRSAHLQMMAVDEEHNKDAMTMTDLEAQKLGSVLLSDVEMGGKILLKAIPI
HHHHHHHHHHCCCCEEEEEECCCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCEEEHHHCC
LDGEMLTDAKVVYDQNNQPVVSFTLDAQGAKIFGDFSGANVGKRMAIVLDNKVYSAPVIR
CCCCCCCCCEEEEECCCCEEEEEEEECCCCEEEECCCCCCCCCEEEEEECCCCCCCHHHH
ERIGGGSGQISGSFSVAQASDLAIALRSGAMKAPIQVLEKRIVGPSLGKDSIKTSINALI
HHCCCCCCCCCCCEEECHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHH
GGFILVLGFMVLYYSMAGVIACVALVVNLFLIVAVMAIFGATLTLPGMAGIVLTVGIAVD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHHEEEHHCC
ANIIINERIREVLREGESIAKAIHLGYINASRAIFDSNITSLIASVLLYAYGTGAIKGFA
CCEEEHHHHHHHHHCCHHHHHHHHHEEECCCHHHHHCCHHHHHHHHHHHHHCCCHHHHHH
LTTGIGILASIITAIIGTQGIYQALLPKLTQTKSLYFWFGVKNKRA
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEEEEECCCCCC
>Mature Secondary Structure
MKLFNFRLIVFVFALFFGVGFSVPSLLETKGPKITLGLDLRGGLNMLLGVQTDEALKNKY
CCEEHHHHHHHHHHHHHHCCCCCCHHHHCCCCEEEEEEECCCCCCEEEECCCHHHHHHHH
LSLASALEYNAKKQNILLKDIKSSLEGVSFELLDEDEAKKLDTLLVELQGHSQFEIKKEA
HHHHHHHHCCCHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHEEECCCCCEEEEECC
EFYSVKLTPLEQEELRKNTILQVIGVIRNRLDQFGLAEPVVIQQGREEISVQLPGIKTLE
EEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCEEEECCCCHHHH
EERRAKDLISRSAHLQMMAVDEEHNKDAMTMTDLEAQKLGSVLLSDVEMGGKILLKAIPI
HHHHHHHHHHCCCCEEEEEECCCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCEEEHHHCC
LDGEMLTDAKVVYDQNNQPVVSFTLDAQGAKIFGDFSGANVGKRMAIVLDNKVYSAPVIR
CCCCCCCCCEEEEECCCCEEEEEEEECCCCEEEECCCCCCCCCEEEEEECCCCCCCHHHH
ERIGGGSGQISGSFSVAQASDLAIALRSGAMKAPIQVLEKRIVGPSLGKDSIKTSINALI
HHCCCCCCCCCCCEEECHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHH
GGFILVLGFMVLYYSMAGVIACVALVVNLFLIVAVMAIFGATLTLPGMAGIVLTVGIAVD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHHEEEHHCC
ANIIINERIREVLREGESIAKAIHLGYINASRAIFDSNITSLIASVLLYAYGTGAIKGFA
CCEEEHHHHHHHHHCCHHHHHHHHHEEECCCHHHHHCCHHHHHHHHHHHHHCCCHHHHHH
LTTGIGILASIITAIIGTQGIYQALLPKLTQTKSLYFWFGVKNKRA
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]