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The map label for this gene is frr

Identifier: 109946849

GI number: 109946849

Start: 196520

End: 197077

Strand: Reverse

Name: frr

Synonym: Hac_0229

Alternate gene names: 109946849

Gene position: 197077-196520 (Counterclockwise)

Preceding gene: 109946850

Following gene: 109946848

Centisome position: 12.68

GC content: 38.71

Gene sequence:

>558_bases
ATGTTACAAACGATTTATAACGAAACCAAAGATTTAATGCAAAAGAGTATTCAAGCCTTAAACAGAGAGTTTTCCACTTT
AAGGAGCGCGAAAGTTTCAGTCAATATTTTAGATCACATTAAGGTAGATTATTACGGCACACCCACGGCTTTAAACCAAG
TCGGCTCCGTGATGAGCTTAGATGCGACTACCCTACAAATTAGCCCTTGGGAAAAAAACCTACTCAAAGAAATTGAAAGG
GCCATTCAAGAAGCCAATATCGGCGTCAATCCTAATAACGATGGCGAAACCATTAAGCTTTTTTTCCCACCCATGACAAC
AGAGCAAAGAAAACTCATCGCAAAAGACGCCAAAGCGATGGGTGAAAAGGCTAAAGTGGCTGTGAGGAATATCCGCCAAG
ACGCTAATAATAAAGTGAAAAAATTGGAAAAAGACAAAGAAATCAGCGAAGATGAAAGCAAGAAAGCCCAAGAACAGGTG
CAAAAAATCACCGATGAAGCCATTAAAAAAATTGATGAAAGCGTGAAAAACAAAGAAGATGCGATTTTAAAGGTCTAA

Upstream 100 bases:

>100_bases
CCAAAGAAAACGCAAAAACGCACCCAACCACCCAGCACAAACCCAAAACGCATGCAACGCAAACCAACGCCCATAAAAAC
CAAAAAAAGGATGAAAAATA

Downstream 100 bases:

>100_bases
ACAATGGATGTCAAAGCATGTTATCAAAACGCTAAAGCGTTGTTGGAGGGGCATTTCTTACTCAGTAGCGGGTTTCATTC
TAACTACTATTTGCAATCTG

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MLQTIYNETKDLMQKSIQALNREFSTLRSAKVSVNILDHIKVDYYGTPTALNQVGSVMSLDATTLQISPWEKNLLKEIER
AIQEANIGVNPNNDGETIKLFFPPMTTEQRKLIAKDAKAMGEKAKVAVRNIRQDANNKVKKLEKDKEISEDESKKAQEQV
QKITDEAIKKIDESVKNKEDAILKV

Sequences:

>Translated_185_residues
MLQTIYNETKDLMQKSIQALNREFSTLRSAKVSVNILDHIKVDYYGTPTALNQVGSVMSLDATTLQISPWEKNLLKEIER
AIQEANIGVNPNNDGETIKLFFPPMTTEQRKLIAKDAKAMGEKAKVAVRNIRQDANNKVKKLEKDKEISEDESKKAQEQV
QKITDEAIKKIDESVKNKEDAILKV
>Mature_185_residues
MLQTIYNETKDLMQKSIQALNREFSTLRSAKVSVNILDHIKVDYYGTPTALNQVGSVMSLDATTLQISPWEKNLLKEIER
AIQEANIGVNPNNDGETIKLFFPPMTTEQRKLIAKDAKAMGEKAKVAVRNIRQDANNKVKKLEKDKEISEDESKKAQEQV
QKITDEAIKKIDESVKNKEDAILKV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family

Homologues:

Organism=Homo sapiens, GI20270317, Length=176, Percent_Identity=30.1136363636364, Blast_Score=64, Evalue=7e-11,
Organism=Escherichia coli, GI1786368, Length=179, Percent_Identity=43.5754189944134, Blast_Score=163, Evalue=6e-42,
Organism=Drosophila melanogaster, GI24661488, Length=172, Percent_Identity=25.5813953488372, Blast_Score=68, Evalue=3e-12,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): RRF_HELAH (Q17Z48)

Other databases:

- EMBL:   AM260522
- RefSeq:   YP_664077.1
- ProteinModelPortal:   Q17Z48
- SMR:   Q17Z48
- STRING:   Q17Z48
- GeneID:   4176524
- GenomeReviews:   AM260522_GR
- KEGG:   hac:Hac_0229
- NMPDR:   fig|382638.8.peg.222
- eggNOG:   COG0233
- HOGENOM:   HBG533975
- OMA:   YYGAETP
- PhylomeDB:   Q17Z48
- ProtClustDB:   PRK00083
- BioCyc:   HACI382638:HAC_0229-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00040
- InterPro:   IPR002661
- InterPro:   IPR015998
- PANTHER:   PTHR20982
- PANTHER:   PTHR20982:SF3
- TIGRFAMs:   TIGR00496

Pfam domain/function: PF01765 RRF; SSF55194 Ribosome_recyc_fac

EC number: NA

Molecular weight: Translated: 20943; Mature: 20943

Theoretical pI: Translated: 9.30; Mature: 9.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQTIYNETKDLMQKSIQALNREFSTLRSAKVSVNILDHIKVDYYGTPTALNQVGSVMSL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHEEECCCCCCHHHHHHCHHHCC
DATTLQISPWEKNLLKEIERAIQEANIGVNPNNDGETIKLFFPPMTTEQRKLIAKDAKAM
CCEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHH
GEKAKVAVRNIRQDANNKVKKLEKDKEISEDESKKAQEQVQKITDEAIKKIDESVKNKED
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
AILKV
CEECC
>Mature Secondary Structure
MLQTIYNETKDLMQKSIQALNREFSTLRSAKVSVNILDHIKVDYYGTPTALNQVGSVMSL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHEEECCCCCCHHHHHHCHHHCC
DATTLQISPWEKNLLKEIERAIQEANIGVNPNNDGETIKLFFPPMTTEQRKLIAKDAKAM
CCEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHH
GEKAKVAVRNIRQDANNKVKKLEKDKEISEDESKKAQEQVQKITDEAIKKIDESVKNKED
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
AILKV
CEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA