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The map label for this gene is nuoA [H]

Identifier: 109946845

GI number: 109946845

Start: 194011

End: 194412

Strand: Reverse

Name: nuoA [H]

Synonym: Hac_0224

Alternate gene names: 109946845

Gene position: 194412-194011 (Counterclockwise)

Preceding gene: 109946846

Following gene: 109946844

Centisome position: 12.51

GC content: 38.06

Gene sequence:

>402_bases
ATGCAACAAGCCACAGAAGCATTGAATCACCCCTATTTTGGCGTTTTTATTTTACTGGTATTCACTTTTTGGGTGTTTAA
CTTAACCTTAAGGATCCAAAGGTTTTTAAGCCGAAAGATGGCTCAAAAAAAGGGCGAAAAGCTCAAGCTCGCTCCCTATG
AGTGTGGACCTGTGGCTCTCAAGCAACCTAATAGAGTGTCGCACCATTTCTATATCATGGCCATGCTTTTTATTTTATTT
GATGTAGAGATCGTTTTCATGTTCCCTTGGGCGATTGATTTTAAAAAGTTAGGCTTGTTTGGGCTCGTTGAAATGCTAGG
CTTTGTTTTCTTTTTAACGATTGGTTTTATTTACGCTTTAAAGCGAAATGCTTTGAGTTGGCAAAATTTAGAGGTGAAAT
AA

Upstream 100 bases:

>100_bases
AGTGTCTAATTTTTATTTTTTCAGCTAACGATTAGCAAAAACATGGTTTAATTGGTTTCATCATTTGCTAAAAGTAATAA
TATAAGGAGTTTGAGGTCTG

Downstream 100 bases:

>100_bases
TGCAACAAGCACCGGTTGTTCTAAGCACTTTGGATAAATTATTGAATTGGGGGCGTTCTAATTCGCTTTGGCCCTTAACC
TATGGCTTGGCGTGTTGTGC

Product: NADH dehydrogenase subunit A

Products: NA

Alternate protein names: NADH dehydrogenase I subunit A 1; NDH-1 subunit A 1; NUO1 1 [H]

Number of amino acids: Translated: 133; Mature: 133

Protein sequence:

>133_residues
MQQATEALNHPYFGVFILLVFTFWVFNLTLRIQRFLSRKMAQKKGEKLKLAPYECGPVALKQPNRVSHHFYIMAMLFILF
DVEIVFMFPWAIDFKKLGLFGLVEMLGFVFFLTIGFIYALKRNALSWQNLEVK

Sequences:

>Translated_133_residues
MQQATEALNHPYFGVFILLVFTFWVFNLTLRIQRFLSRKMAQKKGEKLKLAPYECGPVALKQPNRVSHHFYIMAMLFILF
DVEIVFMFPWAIDFKKLGLFGLVEMLGFVFFLTIGFIYALKRNALSWQNLEVK
>Mature_133_residues
MQQATEALNHPYFGVFILLVFTFWVFNLTLRIQRFLSRKMAQKKGEKLKLAPYECGPVALKQPNRVSHHFYIMAMLFILF
DVEIVFMFPWAIDFKKLGLFGLVEMLGFVFFLTIGFIYALKRNALSWQNLEVK

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0838

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 3 (chain A)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 3 family [H]

Homologues:

Organism=Escherichia coli, GI1788625, Length=129, Percent_Identity=30.2325581395349, Blast_Score=64, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023043
- InterPro:   IPR000440 [H]

Pfam domain/function: PF00507 Oxidored_q4 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 15677; Mature: 15677

Theoretical pI: Translated: 10.32; Mature: 10.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQATEALNHPYFGVFILLVFTFWVFNLTLRIQRFLSRKMAQKKGEKLKLAPYECGPVAL
CCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCC
KQPNRVSHHFYIMAMLFILFDVEIVFMFPWAIDFKKLGLFGLVEMLGFVFFLTIGFIYAL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KRNALSWQNLEVK
HHCCCCCCCCCCC
>Mature Secondary Structure
MQQATEALNHPYFGVFILLVFTFWVFNLTLRIQRFLSRKMAQKKGEKLKLAPYECGPVAL
CCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCC
KQPNRVSHHFYIMAMLFILFDVEIVFMFPWAIDFKKLGLFGLVEMLGFVFFLTIGFIYAL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KRNALSWQNLEVK
HHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA