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The map label for this gene is nadA [H]

Identifier: 109946821

GI number: 109946821

Start: 167521

End: 168531

Strand: Direct

Name: nadA [H]

Synonym: Hac_0199

Alternate gene names: 109946821

Gene position: 167521-168531 (Clockwise)

Preceding gene: 109946820

Following gene: 109946822

Centisome position: 10.78

GC content: 39.37

Gene sequence:

>1011_bases
ATGCCAACTGACAGCGATTTAAAAGCCTCTATTGTAGAATTATTAAACGATTTAGACGTGCTTTTAGTGGCTCATTTTTA
TCAAAAAGATGAGATTGTGGAATTGGCTCATCATTCAGGCGATAGCTTGGAATTGGCTAAAATCGCAAGCCAAAGCGATA
AAAACCTCATCGTGTTTTGTGGGGTGCGTTTTATGGGTGAGAGCGTGAAAGCCCTAGCCTATAATAAACAAGTGATCATG
CCCAAACTCTCATGCTGCTCCATGGCGAGAATGATAGACAGCCAATACTATGATAAGAGCGTTAGCCTTTTAAAAGAATA
CGGCATTAAAGAATTTTACCCTATCACTTATATTAATTCTAACGCCGAAGTGAAAGCCAAAGTCGCCAAAGATAACGGCG
TGGTATGCACCAGCAGGAACGCTTCTAAGATCTTTGATCACGCCCTAAAACAAAATAAAAAAATCTTTTTTTTACCCGAT
CGGTGTTTGGGGGAAAATCTAGCCCTAGAAAATGGCTTAAAAAGTGCCATTTTAGGCGTGAGTAGTCAAGAAGAAATCCA
AAACGCTGATGTCATTTGTTATAACGGCTTTTGCTCCGTACATCAGCTCTTCAAACTAGAAGACATTGAATTTTATCGCC
AAAAATACCCAGATATTTTAATCGCTGTCCATCCAGAGTGCGAGCCTAGCGTGGTTTCTAATGCGGATTTTAGCGGATCA
ACGAGCCAAATCATAGAATTTGTAGAAAAGTTAAGCCCCAATCAAAAAGTCGCCATAGGCACTGAAAGCAATTTAGTCAA
TCGCTTGAAAGCCAAGCGAAATGATCAAAACACTTTTATCCTTTCTAGCACGCTAGCGCTCTGTCCTACCATGAATGAAA
CGACTTTAAAAGATTTGTTTGAAGTCTTAAAGGCCTATAAAAACCACAGGGCTTTCAATATGATTGAATTAAAAGATGAG
GTGGCTCGTTTGGCTAAACTCGCTTTAACTAAAATGATGGAGTTGTCATAA

Upstream 100 bases:

>100_bases
TTTGAAATGGGATCTACTGTTGTTTTATTCACTCAAAATATCGCTTTTAAAGAATTAAGGGAAAAAAGCGTGAAGTTTGG
GGAAAGTATAGGGGAATTTC

Downstream 100 bases:

>100_bases
TGGAGATTAGAGCCTTTTTAGAATTTGCTTTAAAAGAAGATTTGGGGCATGGGGATTTGTTTGAAAGGGTGCTAGAAAAG
GATTTTAAAGCCACAGCCTA

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MPTDSDLKASIVELLNDLDVLLVAHFYQKDEIVELAHHSGDSLELAKIASQSDKNLIVFCGVRFMGESVKALAYNKQVIM
PKLSCCSMARMIDSQYYDKSVSLLKEYGIKEFYPITYINSNAEVKAKVAKDNGVVCTSRNASKIFDHALKQNKKIFFLPD
RCLGENLALENGLKSAILGVSSQEEIQNADVICYNGFCSVHQLFKLEDIEFYRQKYPDILIAVHPECEPSVVSNADFSGS
TSQIIEFVEKLSPNQKVAIGTESNLVNRLKAKRNDQNTFILSSTLALCPTMNETTLKDLFEVLKAYKNHRAFNMIELKDE
VARLAKLALTKMMELS

Sequences:

>Translated_336_residues
MPTDSDLKASIVELLNDLDVLLVAHFYQKDEIVELAHHSGDSLELAKIASQSDKNLIVFCGVRFMGESVKALAYNKQVIM
PKLSCCSMARMIDSQYYDKSVSLLKEYGIKEFYPITYINSNAEVKAKVAKDNGVVCTSRNASKIFDHALKQNKKIFFLPD
RCLGENLALENGLKSAILGVSSQEEIQNADVICYNGFCSVHQLFKLEDIEFYRQKYPDILIAVHPECEPSVVSNADFSGS
TSQIIEFVEKLSPNQKVAIGTESNLVNRLKAKRNDQNTFILSSTLALCPTMNETTLKDLFEVLKAYKNHRAFNMIELKDE
VARLAKLALTKMMELS
>Mature_335_residues
PTDSDLKASIVELLNDLDVLLVAHFYQKDEIVELAHHSGDSLELAKIASQSDKNLIVFCGVRFMGESVKALAYNKQVIMP
KLSCCSMARMIDSQYYDKSVSLLKEYGIKEFYPITYINSNAEVKAKVAKDNGVVCTSRNASKIFDHALKQNKKIFFLPDR
CLGENLALENGLKSAILGVSSQEEIQNADVICYNGFCSVHQLFKLEDIEFYRQKYPDILIAVHPECEPSVVSNADFSGST
SQIIEFVEKLSPNQKVAIGTESNLVNRLKAKRNDQNTFILSSTLALCPTMNETTLKDLFEVLKAYKNHRAFNMIELKDEV
ARLAKLALTKMMELS

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 3 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=343, Percent_Identity=27.1137026239067, Blast_Score=135, Evalue=3e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 37716; Mature: 37585

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTDSDLKASIVELLNDLDVLLVAHFYQKDEIVELAHHSGDSLELAKIASQSDKNLIVFC
CCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCHHHHHHCCCCCCEEEEE
GVRFMGESVKALAYNKQVIMPKLSCCSMARMIDSQYYDKSVSLLKEYGIKEFYPITYINS
CHHHHCCHHHHHHHCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECC
NAEVKAKVAKDNGVVCTSRNASKIFDHALKQNKKIFFLPDRCLGENLALENGLKSAILGV
CCEEEEEEECCCCEEEECCCHHHHHHHHHHCCCEEEEECHHHCCCCHHHHHCHHHHHHCC
SSQEEIQNADVICYNGFCSVHQLFKLEDIEFYRQKYPDILIAVHPECEPSVVSNADFSGS
CCHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCC
TSQIIEFVEKLSPNQKVAIGTESNLVNRLKAKRNDQNTFILSSTLALCPTMNETTLKDLF
HHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHCCCCCEEEEEHHHHHCCCCCHHHHHHHH
EVLKAYKNHRAFNMIELKDEVARLAKLALTKMMELS
HHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PTDSDLKASIVELLNDLDVLLVAHFYQKDEIVELAHHSGDSLELAKIASQSDKNLIVFC
CCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCHHHHHHCCCCCCEEEEE
GVRFMGESVKALAYNKQVIMPKLSCCSMARMIDSQYYDKSVSLLKEYGIKEFYPITYINS
CHHHHCCHHHHHHHCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECC
NAEVKAKVAKDNGVVCTSRNASKIFDHALKQNKKIFFLPDRCLGENLALENGLKSAILGV
CCEEEEEEECCCCEEEECCCHHHHHHHHHHCCCEEEEECHHHCCCCHHHHHCHHHHHHCC
SSQEEIQNADVICYNGFCSVHQLFKLEDIEFYRQKYPDILIAVHPECEPSVVSNADFSGS
CCHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCC
TSQIIEFVEKLSPNQKVAIGTESNLVNRLKAKRNDQNTFILSSTLALCPTMNETTLKDLF
HHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHCCCCCEEEEEHHHHHCCCCCHHHHHHHH
EVLKAYKNHRAFNMIELKDEVARLAKLALTKMMELS
HHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA