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The map label for this gene is phoR [H]

Identifier: 109946813

GI number: 109946813

Start: 159479

End: 160591

Strand: Direct

Name: phoR [H]

Synonym: Hac_0191

Alternate gene names: 109946813

Gene position: 159479-160591 (Clockwise)

Preceding gene: 109946812

Following gene: 109946814

Centisome position: 10.26

GC content: 35.13

Gene sequence:

>1113_bases
ATGCTAGTGATTAGCGTTTTAGTGTTTAATTATGAAAAAAACGAAAAAATCAAAATGATACGCATGGATATGGACAAAAT
GGCTTCTAAAATCGCTAGTGAAGTGATCCAATTACACATGCAAACGCATACAGATTATCACAACGCTTTAAACGCCCTTA
TTTCACGTTATAAAGACGCTTCCATAGCGCTTTTTGATAATAAAAGGCGTGTTTTGTATTCTAATATCCCTGAAAGCATG
GATTTGATTAAAAACCATAGAGAGGCAGGCTTTTTTAGTTTTAAGAGGGAGTATTATCTTATGACTGATGAAACTTTCGC
TCATTTAGGCGTGGCTAAAATGCTTTTTAAAAACGCTAAACCCCTTAATTTTTCTTCTTTGTATCGTAATATTGTTTTAG
TGTTTTTCGTAGCGTTTTTATGTGTGATAGGGGTTTCTGTGTTTTTAGGGCGTTTGTTTTTAAAGCCCATTAGGAATGAA
ATCACGCGCATTGATCATTTTTTAAAAAACACCACGCATGAATTAAACACCCCCATGAGCGCTTTAGTCTTATCCTTAAA
AACTTTAGAAGACAATCAAAAACACCGCCGCATTAAAATCGCTATCCAGCGCATGAGCTTTTTATACCGCTCGCTCTCTT
ATTTAGTGATGCAAGATATTGGGCGCGAATCCCCTATACTTTTAGATTTAAAATCCCTAATCCTTAAAGAAAACACGCTT
TTTAGCGAGATGATAGACTACCACAAGTTGGAATTTAAAAGCGATTTAGTGCAAGTCAAATTGAAAGCTAGGGAGCAGGA
TTTCCTTTCGCTTTATAGCAATTTGCTCATGAATGCGATCAAATACAGCGTAGTGCATGGGTATATTCACATAGAGCTAA
CGCCTAAGTTTTTGAAAGTGAAAAATTTAGGGTATGAAATCCCTAAAGACAAGATCACAGAATTAAGCGTTCGTTATGCA
CGTTTCAATTCTAGCGTGTTGGGTTATGGTATAGGGTTAGATTTAGTTAAAAAAGTGTGCGAAAAGTATAAAATGCGTTT
AGAAATTCATAGCGAGCCTTCTTTAAAAGGGTCGTTTTATGAAAATTCGTTTTGTATTTATTTTCAAGGATAA

Upstream 100 bases:

>100_bases
ATAGAAACGCACAAGGGGGTGGGCTATTGCTTTAACCCACTATGAAAAAAAATCCCTTAAACTCTTTTTAGGGACTTATT
TAGGCTCTTCGTTTGTTTTA

Downstream 100 bases:

>100_bases
AGATGCTTTCAGTGTATGAAAAAGTGAATGCCCTAGACAAAAGGGCGCTTGAAGAATTGCTTTTGAGTGAAGATATTTTA
ATGGAAAACGCTGCGATGGC

Product: signal-transducing protein, histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 370; Mature: 370

Protein sequence:

>370_residues
MLVISVLVFNYEKNEKIKMIRMDMDKMASKIASEVIQLHMQTHTDYHNALNALISRYKDASIALFDNKRRVLYSNIPESM
DLIKNHREAGFFSFKREYYLMTDETFAHLGVAKMLFKNAKPLNFSSLYRNIVLVFFVAFLCVIGVSVFLGRLFLKPIRNE
ITRIDHFLKNTTHELNTPMSALVLSLKTLEDNQKHRRIKIAIQRMSFLYRSLSYLVMQDIGRESPILLDLKSLILKENTL
FSEMIDYHKLEFKSDLVQVKLKAREQDFLSLYSNLLMNAIKYSVVHGYIHIELTPKFLKVKNLGYEIPKDKITELSVRYA
RFNSSVLGYGIGLDLVKKVCEKYKMRLEIHSEPSLKGSFYENSFCIYFQG

Sequences:

>Translated_370_residues
MLVISVLVFNYEKNEKIKMIRMDMDKMASKIASEVIQLHMQTHTDYHNALNALISRYKDASIALFDNKRRVLYSNIPESM
DLIKNHREAGFFSFKREYYLMTDETFAHLGVAKMLFKNAKPLNFSSLYRNIVLVFFVAFLCVIGVSVFLGRLFLKPIRNE
ITRIDHFLKNTTHELNTPMSALVLSLKTLEDNQKHRRIKIAIQRMSFLYRSLSYLVMQDIGRESPILLDLKSLILKENTL
FSEMIDYHKLEFKSDLVQVKLKAREQDFLSLYSNLLMNAIKYSVVHGYIHIELTPKFLKVKNLGYEIPKDKITELSVRYA
RFNSSVLGYGIGLDLVKKVCEKYKMRLEIHSEPSLKGSFYENSFCIYFQG
>Mature_370_residues
MLVISVLVFNYEKNEKIKMIRMDMDKMASKIASEVIQLHMQTHTDYHNALNALISRYKDASIALFDNKRRVLYSNIPESM
DLIKNHREAGFFSFKREYYLMTDETFAHLGVAKMLFKNAKPLNFSSLYRNIVLVFFVAFLCVIGVSVFLGRLFLKPIRNE
ITRIDHFLKNTTHELNTPMSALVLSLKTLEDNQKHRRIKIAIQRMSFLYRSLSYLVMQDIGRESPILLDLKSLILKENTL
FSEMIDYHKLEFKSDLVQVKLKAREQDFLSLYSNLLMNAIKYSVVHGYIHIELTPKFLKVKNLGYEIPKDKITELSVRYA
RFNSSVLGYGIGLDLVKKVCEKYKMRLEIHSEPSLKGSFYENSFCIYFQG

Specific function: Member of the two-component regulatory system phoR/phoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates phoB in response to environmental signals [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR021766
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR014310 [H]

Pfam domain/function: PF11808 DUF3329; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 43273; Mature: 43273

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVISVLVFNYEKNEKIKMIRMDMDKMASKIASEVIQLHMQTHTDYHNALNALISRYKDA
CEEEEEEEEECCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCC
SIALFDNKRRVLYSNIPESMDLIKNHREAGFFSFKREYYLMTDETFAHLGVAKMLFKNAK
EEEEEECCCEEEECCCCHHHHHHHHHHHCCCEEECCEEEEEECCHHHHHHHHHHHHCCCC
PLNFSSLYRNIVLVFFVAFLCVIGVSVFLGRLFLKPIRNEITRIDHFLKNTTHELNTPMS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHH
ALVLSLKTLEDNQKHRRIKIAIQRMSFLYRSLSYLVMQDIGRESPILLDLKSLILKENTL
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHH
FSEMIDYHKLEFKSDLVQVKLKAREQDFLSLYSNLLMNAIKYSVVHGYIHIELTPKFLKV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEECHHHHHH
KNLGYEIPKDKITELSVRYARFNSSVLGYGIGLDLVKKVCEKYKMRLEIHSEPSLKGSFY
HHCCCCCCCHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHEEEECCCCCCCCCEE
ENSFCIYFQG
CCCEEEEEEC
>Mature Secondary Structure
MLVISVLVFNYEKNEKIKMIRMDMDKMASKIASEVIQLHMQTHTDYHNALNALISRYKDA
CEEEEEEEEECCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCC
SIALFDNKRRVLYSNIPESMDLIKNHREAGFFSFKREYYLMTDETFAHLGVAKMLFKNAK
EEEEEECCCEEEECCCCHHHHHHHHHHHCCCEEECCEEEEEECCHHHHHHHHHHHHCCCC
PLNFSSLYRNIVLVFFVAFLCVIGVSVFLGRLFLKPIRNEITRIDHFLKNTTHELNTPMS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHH
ALVLSLKTLEDNQKHRRIKIAIQRMSFLYRSLSYLVMQDIGRESPILLDLKSLILKENTL
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHH
FSEMIDYHKLEFKSDLVQVKLKAREQDFLSLYSNLLMNAIKYSVVHGYIHIELTPKFLKV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEECHHHHHH
KNLGYEIPKDKITELSVRYARFNSSVLGYGIGLDLVKKVCEKYKMRLEIHSEPSLKGSFY
HHCCCCCCCHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHEEEECCCCCCCCCEE
ENSFCIYFQG
CCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043; 2115874 [H]