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The map label for this gene is arlR [H]

Identifier: 109946812

GI number: 109946812

Start: 158782

End: 159423

Strand: Direct

Name: arlR [H]

Synonym: Hac_0190

Alternate gene names: 109946812

Gene position: 158782-159423 (Clockwise)

Preceding gene: 109946811

Following gene: 109946813

Centisome position: 10.22

GC content: 36.29

Gene sequence:

>642_bases
ATGCAAAAAAAGATTTTTTTACTAGAAGATGATTACCTTTTAAGCGAGAGCGTTAAGGAGTTTTTAGAGCATTTGGGCTA
TAAAGTAGTTTGTGCTTTTAACGGAAAAGAGGCTTATGAAAGGCTTTCTGTTGAGCGTTTTAATCTCTTGCTTTTAGATG
TGCAAGTGCCTGAAATGAATAGCTTGGAATTGTTTAAGTGCATCAAAAACGATTTTTTAATCTCTACGCCTGTGATTTTT
ATCACCGCTTTACAAGATAACGCCACCTTAAAATGCGCTTTTAATTTAGGTGCAAGCGATTATTTGAAAAAGCCTTTTGA
TTTAGACGAATTAGAAGCACGCATTAAAAGGTTTTTCAATGATGATCCGATAGAAATCATGCCTGATGTTTTTTATTCCC
AACACTCTTTGAATGTCAAGGGGAAAAAGGAAATCTTAGCGCCCAAAACCGCCCAACTTTTAGAGTATTTCTTAGAGCAT
AAGGGGCAAATCATTAGCTCTCAAGTGTTAGAAAATAACTTATGGGATCAAGCTATTGATGACTCCACCTTACGCACTTA
TATTAAAGTGTTGCGTAAGCTTTTAGGGAAAAATTGCATAGAAACGCACAAGGGGGTGGGCTATTGCTTTAACCCACTAT
GA

Upstream 100 bases:

>100_bases
AACTTCATAAAATTTAGCTTCGTTCGTTTTCATTATAGCTCCCTTAAAAACATGAAAGAGTATTATAGCAAAGCCTACCA
TTAAGCGCTACAATACCCCC

Downstream 100 bases:

>100_bases
AAAAAAATCCCTTAAACTCTTTTTAGGGACTTATTTAGGCTCTTCGTTTGTTTTAATGCTAGTGATTAGCGTTTTAGTGT
TTAATTATGAAAAAAACGAA

Product: two-component regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 213; Mature: 213

Protein sequence:

>213_residues
MQKKIFLLEDDYLLSESVKEFLEHLGYKVVCAFNGKEAYERLSVERFNLLLLDVQVPEMNSLELFKCIKNDFLISTPVIF
ITALQDNATLKCAFNLGASDYLKKPFDLDELEARIKRFFNDDPIEIMPDVFYSQHSLNVKGKKEILAPKTAQLLEYFLEH
KGQIISSQVLENNLWDQAIDDSTLRTYIKVLRKLLGKNCIETHKGVGYCFNPL

Sequences:

>Translated_213_residues
MQKKIFLLEDDYLLSESVKEFLEHLGYKVVCAFNGKEAYERLSVERFNLLLLDVQVPEMNSLELFKCIKNDFLISTPVIF
ITALQDNATLKCAFNLGASDYLKKPFDLDELEARIKRFFNDDPIEIMPDVFYSQHSLNVKGKKEILAPKTAQLLEYFLEH
KGQIISSQVLENNLWDQAIDDSTLRTYIKVLRKLLGKNCIETHKGVGYCFNPL
>Mature_213_residues
MQKKIFLLEDDYLLSESVKEFLEHLGYKVVCAFNGKEAYERLSVERFNLLLLDVQVPEMNSLELFKCIKNDFLISTPVIF
ITALQDNATLKCAFNLGASDYLKKPFDLDELEARIKRFFNDDPIEIMPDVFYSQHSLNVKGKKEILAPKTAQLLEYFLEH
KGQIISSQVLENNLWDQAIDDSTLRTYIKVLRKLLGKNCIETHKGVGYCFNPL

Specific function: Member of the two-component regulatory system ArlS/ArlR [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789402, Length=217, Percent_Identity=26.7281105990783, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1790552, Length=217, Percent_Identity=29.9539170506912, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1786784, Length=222, Percent_Identity=26.5765765765766, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1786599, Length=226, Percent_Identity=28.3185840707965, Blast_Score=84, Evalue=6e-18,
Organism=Escherichia coli, GI1786911, Length=222, Percent_Identity=25.6756756756757, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1790860, Length=230, Percent_Identity=26.9565217391304, Blast_Score=77, Evalue=9e-16,
Organism=Escherichia coli, GI87082012, Length=220, Percent_Identity=27.7272727272727, Blast_Score=75, Evalue=2e-15,
Organism=Escherichia coli, GI1787229, Length=225, Percent_Identity=25.7777777777778, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI2367329, Length=234, Percent_Identity=29.4871794871795, Blast_Score=68, Evalue=4e-13,
Organism=Escherichia coli, GI1790299, Length=124, Percent_Identity=36.2903225806452, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1790437, Length=113, Percent_Identity=33.6283185840708, Blast_Score=64, Evalue=5e-12,
Organism=Escherichia coli, GI1789809, Length=231, Percent_Identity=24.2424242424242, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1788394, Length=225, Percent_Identity=24.4444444444444, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1788550, Length=114, Percent_Identity=30.7017543859649, Blast_Score=62, Evalue=2e-11,
Organism=Escherichia coli, GI1787375, Length=221, Percent_Identity=24.4343891402715, Blast_Score=60, Evalue=9e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 24637; Mature: 24637

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKKIFLLEDDYLLSESVKEFLEHLGYKVVCAFNGKEAYERLSVERFNLLLLDVQVPEMN
CCCEEEEEECCHHHHHHHHHHHHHCCEEEEEEECCHHHHHHHHHHHEEEEEEEEECCCCC
SLELFKCIKNDFLISTPVIFITALQDNATLKCAFNLGASDYLKKPFDLDELEARIKRFFN
HHHHHHHHHCCCEEECCEEEEEEECCCCEEEEEEECCCHHHHCCCCCHHHHHHHHHHHCC
DDPIEIMPDVFYSQHSLNVKGKKEILAPKTAQLLEYFLEHKGQIISSQVLENNLWDQAID
CCCHHHCCHHHHCCCCCCCCCCHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHCHHHHHCC
DSTLRTYIKVLRKLLGKNCIETHKGVGYCFNPL
HHHHHHHHHHHHHHHCCHHHHHHCCCCEECCCC
>Mature Secondary Structure
MQKKIFLLEDDYLLSESVKEFLEHLGYKVVCAFNGKEAYERLSVERFNLLLLDVQVPEMN
CCCEEEEEECCHHHHHHHHHHHHHCCEEEEEEECCHHHHHHHHHHHEEEEEEEEECCCCC
SLELFKCIKNDFLISTPVIFITALQDNATLKCAFNLGASDYLKKPFDLDELEARIKRFFN
HHHHHHHHHCCCEEECCEEEEEEECCCCEEEEEEECCCHHHHCCCCCHHHHHHHHHHHCC
DDPIEIMPDVFYSQHSLNVKGKKEILAPKTAQLLEYFLEHKGQIISSQVLENNLWDQAID
CCCHHHCCHHHHCCCCCCCCCCHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHCHHHHHCC
DSTLRTYIKVLRKLLGKNCIETHKGVGYCFNPL
HHHHHHHHHHHHHHHCCHHHHHHCCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA