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The map label for this gene is rnhB

Identifier: 109946755

GI number: 109946755

Start: 121877

End: 122458

Strand: Direct

Name: rnhB

Synonym: Hac_0132

Alternate gene names: 109946755

Gene position: 121877-122458 (Clockwise)

Preceding gene: 109946754

Following gene: 109946758

Centisome position: 7.84

GC content: 39.69

Gene sequence:

>582_bases
ATGACTCTAGGCATTGATGAAGCGGGTAGGGGGTGTTTGGTTGGTTCGCTTTTTGTGGCTGGGGTGGTGTGCGGTGAAAA
AATAGCCTTAGATTTTCTAAAAATGGGTCTTAAAGATAGCAAAAAACTCAGCCAAAATAAGCGCTTTTTCTTAGAAGATA
AAATCAAATCGCATGATGAGGTCAAATTTTGCGTAATTAAAAAAAGCGCAGGTGAAATTGATAGCTTGAGTTTGGGGGTA
TGCTTGAAACTCGCTGTGCAAGAAATTTTAGAAAAGCTAAGCCCTTTAGCTCAAACAATCAATATAGACGGCAACACAGC
GTTTGGTTTGAATAAACGCTATTCTAATCTAAAAACGATCATCAAGGGCGATGAGAAAATCGCTCAAATCGCTATGGCGT
CTGTTCTAGCAAAAACTTCCAAAGATAGAGAAATGCTAGAATTGCACGCCTTGTTTAAGGAATACGGTTGGGATAAGAAT
TGCGGGTATGGGACTAAAAAACACATAGAAGCGATTGCTAAACTAGGGGCTACGCCCTTTCACAGGCATAGCTTTGCACT
TAAAAACAACTGGTTTTCTTAA

Upstream 100 bases:

>100_bases
GAATAACAATCAAAATTCAAGCATGGAGTGTTTTTTGGCATTCAAGTTGCAAAGGAAAATTTTAAACCAAAAGACAACAC
TAAAAAATAAGGCATTTTAA

Downstream 100 bases:

>100_bases
GTGTCCACATTAAATAGCACCTTGTTTAAAACCACGCTCAAACTTTTAGCGCTTTTTGGAGAAAGTTCGATATTTTTCCC
TTTGAAATGAGCGATAAGAT

Product: ribonuclease HII

Products: NA

Alternate protein names: RNase HII

Number of amino acids: Translated: 193; Mature: 192

Protein sequence:

>193_residues
MTLGIDEAGRGCLVGSLFVAGVVCGEKIALDFLKMGLKDSKKLSQNKRFFLEDKIKSHDEVKFCVIKKSAGEIDSLSLGV
CLKLAVQEILEKLSPLAQTINIDGNTAFGLNKRYSNLKTIIKGDEKIAQIAMASVLAKTSKDREMLELHALFKEYGWDKN
CGYGTKKHIEAIAKLGATPFHRHSFALKNNWFS

Sequences:

>Translated_193_residues
MTLGIDEAGRGCLVGSLFVAGVVCGEKIALDFLKMGLKDSKKLSQNKRFFLEDKIKSHDEVKFCVIKKSAGEIDSLSLGV
CLKLAVQEILEKLSPLAQTINIDGNTAFGLNKRYSNLKTIIKGDEKIAQIAMASVLAKTSKDREMLELHALFKEYGWDKN
CGYGTKKHIEAIAKLGATPFHRHSFALKNNWFS
>Mature_192_residues
TLGIDEAGRGCLVGSLFVAGVVCGEKIALDFLKMGLKDSKKLSQNKRFFLEDKIKSHDEVKFCVIKKSAGEIDSLSLGVC
LKLAVQEILEKLSPLAQTINIDGNTAFGLNKRYSNLKTIIKGDEKIAQIAMASVLAKTSKDREMLELHALFKEYGWDKNC
GYGTKKHIEAIAKLGATPFHRHSFALKNNWFS

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids

COG id: COG0164

COG function: function code L; Ribonuclease HII

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase HII family

Homologues:

Organism=Escherichia coli, GI1786380, Length=185, Percent_Identity=35.1351351351351, Blast_Score=110, Evalue=7e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNH2_HELAH (Q17ZE2)

Other databases:

- EMBL:   AM260522
- RefSeq:   YP_663983.1
- ProteinModelPortal:   Q17ZE2
- SMR:   Q17ZE2
- STRING:   Q17ZE2
- GeneID:   4177096
- GenomeReviews:   AM260522_GR
- KEGG:   hac:Hac_0132
- NMPDR:   fig|382638.8.peg.129
- eggNOG:   COG0164
- HOGENOM:   HBG584843
- OMA:   IICGVDE
- ProtClustDB:   PRK14550
- BioCyc:   HACI382638:HAC_0132-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00052_B
- InterPro:   IPR022898
- InterPro:   IPR001352
- InterPro:   IPR012337
- PANTHER:   PTHR10954

Pfam domain/function: PF01351 RNase_HII; SSF53098 RNaseH_fold

EC number: =3.1.26.4

Molecular weight: Translated: 21352; Mature: 21221

Theoretical pI: Translated: 9.65; Mature: 9.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLGIDEAGRGCLVGSLFVAGVVCGEKIALDFLKMGLKDSKKLSQNKRFFLEDKIKSHDE
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCEEHHHHHCCCCC
VKFCVIKKSAGEIDSLSLGVCLKLAVQEILEKLSPLAQTINIDGNTAFGLNKRYSNLKTI
EEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCHHHHHHHHH
IKGDEKIAQIAMASVLAKTSKDREMLELHALFKEYGWDKNCGYGTKKHIEAIAKLGATPF
HCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCC
HRHSFALKNNWFS
HHHHHHHCCCCCC
>Mature Secondary Structure 
TLGIDEAGRGCLVGSLFVAGVVCGEKIALDFLKMGLKDSKKLSQNKRFFLEDKIKSHDE
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCEEHHHHHCCCCC
VKFCVIKKSAGEIDSLSLGVCLKLAVQEILEKLSPLAQTINIDGNTAFGLNKRYSNLKTI
EEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCHHHHHHHHH
IKGDEKIAQIAMASVLAKTSKDREMLELHALFKEYGWDKNCGYGTKKHIEAIAKLGATPF
HCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCC
HRHSFALKNNWFS
HHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA