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The map label for this gene is ribD [H]

Identifier: 109946711

GI number: 109946711

Start: 77902

End: 78936

Strand: Direct

Name: ribD [H]

Synonym: Hac_0079

Alternate gene names: 109946711

Gene position: 77902-78936 (Clockwise)

Preceding gene: 109946710

Following gene: 109946712

Centisome position: 5.01

GC content: 38.36

Gene sequence:

>1035_bases
ATGAGACTTTATGAGAGTTTATTAGAAATTTGTTTGAATAAGGCGTGGGAATACCAGACCCTAGCCTTAGAAAACCCAAG
TGTGGCTTGCATGGTGTTAGATAAAAACCATGAGATCTTAAGCTTAGAGGTGCATAAAAAAGCCAAAACTCCGCATGCAG
AAGTCTTAGCCACTAAATCGGCGTTGAAGATTTTACGCCCTAGTTTAAAAATCGATTTAGACCAACTAGAAGATCCTAAA
ATCTTAAGCGACTTTTTAAAAACACACCATGATAACGCTTTTAAAGACTGCGTTTTTTTAATCACCCTAGAGCCATGCAA
TTCCTATGGTAAAACCCCCGCATGCAGTGAATTATTAGAAATTTTAAAGCCTAAAAGAGTGGTTATTGCGATAGAAGAAA
ATAAAGCTAAAAAAGGGGGGTTAGAGAGGCTCAAAAAAGCCCATGTTGAAGCGCTCATTTGCCCAAGTTTAGAAAACAAG
GCTAGAGATTTGCTCTTGCCTTTTAGGATAATGGAAAAAAAGGGACGTTTTAATTTATTCAAACTCGCTTTAAGAATGAA
TGGGGATTACCAGCATGGCAAGATCACCGGTCAAAAAAGCGCTATTTTCACGCACAACCAACGAGCGGTATGTGGCACTC
TTATTGTCTCTGGAAAAACCATAAGAACGGATAATCCCTTATTAGATGCACGCTTTTGCGATGGTTTTTATCAAGGTAAA
AACCCTAATATCGCTATTTTATCCAAGCATCCAACTAACTCTCATTTGAGAGTTTTTTCTGCACCTAATCGTTTAGTTAA
TACTTTTCATGACCCTAAGGATTTGCCCTCAGATAAGGGGTTTAATTTCATTGAAGGGGGGTGGGAATTGTTTGAGAGCT
TGAGAGACAAAATAGACATGTTACTTTTGCATTCCCATGCGTCTATGATTGGCGAATCTTTTAGCTCGCTCGCTCTAAAA
ACCCCTTTTAAAGGCCGTTTGTTGCACACGCAAATCTTAGAAAATGAAGCCCTTTTATGGATAGAAAACTCTTAA

Upstream 100 bases:

>100_bases
ATGTGGCGTTTATCGTGGTGCCTTTAGTGGGAGCGTTTTTCATTGACATCATCAACGCTTTGGCGATCAAAGGCTTTTTG
TCCTTACCCTTTTTCCCATC

Downstream 100 bases:

>100_bases
GATTATACCAACCTTTAAACGCTTATGCTTACAATAGCGATTCGCTCTTTTTATACGATTTTTCATGCCCTTTGATTAAA
AATAGTGGTGCGATTTTAGA

Product: diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MRLYESLLEICLNKAWEYQTLALENPSVACMVLDKNHEILSLEVHKKAKTPHAEVLATKSALKILRPSLKIDLDQLEDPK
ILSDFLKTHHDNAFKDCVFLITLEPCNSYGKTPACSELLEILKPKRVVIAIEENKAKKGGLERLKKAHVEALICPSLENK
ARDLLLPFRIMEKKGRFNLFKLALRMNGDYQHGKITGQKSAIFTHNQRAVCGTLIVSGKTIRTDNPLLDARFCDGFYQGK
NPNIAILSKHPTNSHLRVFSAPNRLVNTFHDPKDLPSDKGFNFIEGGWELFESLRDKIDMLLLHSHASMIGESFSSLALK
TPFKGRLLHTQILENEALLWIENS

Sequences:

>Translated_344_residues
MRLYESLLEICLNKAWEYQTLALENPSVACMVLDKNHEILSLEVHKKAKTPHAEVLATKSALKILRPSLKIDLDQLEDPK
ILSDFLKTHHDNAFKDCVFLITLEPCNSYGKTPACSELLEILKPKRVVIAIEENKAKKGGLERLKKAHVEALICPSLENK
ARDLLLPFRIMEKKGRFNLFKLALRMNGDYQHGKITGQKSAIFTHNQRAVCGTLIVSGKTIRTDNPLLDARFCDGFYQGK
NPNIAILSKHPTNSHLRVFSAPNRLVNTFHDPKDLPSDKGFNFIEGGWELFESLRDKIDMLLLHSHASMIGESFSSLALK
TPFKGRLLHTQILENEALLWIENS
>Mature_344_residues
MRLYESLLEICLNKAWEYQTLALENPSVACMVLDKNHEILSLEVHKKAKTPHAEVLATKSALKILRPSLKIDLDQLEDPK
ILSDFLKTHHDNAFKDCVFLITLEPCNSYGKTPACSELLEILKPKRVVIAIEENKAKKGGLERLKKAHVEALICPSLENK
ARDLLLPFRIMEKKGRFNLFKLALRMNGDYQHGKITGQKSAIFTHNQRAVCGTLIVSGKTIRTDNPLLDARFCDGFYQGK
NPNIAILSKHPTNSHLRVFSAPNRLVNTFHDPKDLPSDKGFNFIEGGWELFESLRDKIDMLLLHSHASMIGESFSSLALK
TPFKGRLLHTQILENEALLWIENS

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG0117

COG function: function code H; Pyrimidine deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 38957; Mature: 38957

Theoretical pI: Translated: 8.89; Mature: 8.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLYESLLEICLNKAWEYQTLALENPSVACMVLDKNHEILSLEVHKKAKTPHAEVLATKS
CCHHHHHHHHHHHCCCCEEEEEECCCCEEEEEEECCCCEEEEEEECCCCCCHHHHHHHHH
ALKILRPSLKIDLDQLEDPKILSDFLKTHHDNAFKDCVFLITLEPCNSYGKTPACSELLE
HHHHHCCCCEEEHHHCCCCHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHH
ILKPKRVVIAIEENKAKKGGLERLKKAHVEALICPSLENKARDLLLPFRIMEKKGRFNLF
HHCCCEEEEEEECCCCCCCHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHCCCCCEEE
KLALRMNGDYQHGKITGQKSAIFTHNQRAVCGTLIVSGKTIRTDNPLLDARFCDGFYQGK
EEEEEECCCCCCCEECCCCCEEEECCCCEEEEEEEECCCEEECCCCEEEHHHHCCHHCCC
NPNIAILSKHPTNSHLRVFSAPNRLVNTFHDPKDLPSDKGFNFIEGGWELFESLRDKIDM
CCCEEEEECCCCCCCEEEEECCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
LLLHSHASMIGESFSSLALKTPFKGRLLHTQILENEALLWIENS
HHHHHHHHHHHHHHHHHEECCCCCCCEEHHHHHCCCEEEEEECC
>Mature Secondary Structure
MRLYESLLEICLNKAWEYQTLALENPSVACMVLDKNHEILSLEVHKKAKTPHAEVLATKS
CCHHHHHHHHHHHCCCCEEEEEECCCCEEEEEEECCCCEEEEEEECCCCCCHHHHHHHHH
ALKILRPSLKIDLDQLEDPKILSDFLKTHHDNAFKDCVFLITLEPCNSYGKTPACSELLE
HHHHHCCCCEEEHHHCCCCHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHH
ILKPKRVVIAIEENKAKKGGLERLKKAHVEALICPSLENKARDLLLPFRIMEKKGRFNLF
HHCCCEEEEEEECCCCCCCHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHCCCCCEEE
KLALRMNGDYQHGKITGQKSAIFTHNQRAVCGTLIVSGKTIRTDNPLLDARFCDGFYQGK
EEEEEECCCCCCCEECCCCCEEEECCCCEEEEEEEECCCEEECCCCEEEHHHHCCHHCCC
NPNIAILSKHPTNSHLRVFSAPNRLVNTFHDPKDLPSDKGFNFIEGGWELFESLRDKIDM
CCCEEEEECCCCCCCEEEEECCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
LLLHSHASMIGESFSSLALKTPFKGRLLHTQILENEALLWIENS
HHHHHHHHHHHHHHHHHEECCCCCCCEEHHHHHCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]