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The map label for this gene is llm [H]

Identifier: 109946665

GI number: 109946665

Start: 33765

End: 34772

Strand: Reverse

Name: llm [H]

Synonym: Hac_0030

Alternate gene names: 109946665

Gene position: 34772-33765 (Counterclockwise)

Preceding gene: 109946670

Following gene: 109946664

Centisome position: 2.24

GC content: 39.29

Gene sequence:

>1008_bases
GTGTTGTGGGTGCTATATTTTTTAACCAGTCTATTCATTTGCTCTTTGATTGTTTTGTGGTCTAAAAAATCCACGCTCTT
TGTGGATAACGCCAACAAGATCCAGGGCTTCCATCACGCAAGAACCCCACGAGCTGGGGGGCTTGGGATCTTTCTTTCTT
TCGTGTTGGCTTGTTTTTTTGAGCCTTTAGAGATGCCTTTTAAGGGATCTTTTGTTTTTTTGGGGCTATTATTAGTCTTT
TTGAGCGGCTTTTTAGAAGACATTAACCTTTCGCTTAGCCCCAAAACGCGCCTTATTTTGCAAGGCATAGGGGTCGTTTG
CATCATTTCATCAACGCCTTTAGTGGTGAGCGATTTTTCGCCTCTTTTTAGCCTACCTTATTTTATCGCTTTTTTATTCG
CTATTTTTATGCTTGTAGGTATCAGTAACGCTATCAATATTATTGATGGGTTTAACGGGCTTGCGTCTGGGATTTGCACG
ATCACGCTTTTAATCGTCCATTACATAGAGCCTAATGGTCCATCGTGTTTGTTAGCTTACATGGTGCTTGGGTTTATGGT
GTTAAATTTCCCTTTAGGAAAGATTTTTTTAGGTGATGGGGGGGCGTATTTTTTAGGGTTGGCGTGCGGAATTTCCCTCT
TATATTTGAGTTTAGAGCAAAAAATCAGCGTGTTTTTTGGATTAAATTTAATGCTTTATCCAATCATAGAGGTGCTTTTT
AGTATCCTTAGGCGCAAAATAAAACGCCAAAAAGCCACCATGCCAGATAATTTGCATTTGCACACCCTTTTATTCAAATT
CTTGCAACGGCGCTCTTTGGGTTATCCTAATTCTTTATGCGCCTTTATCATCATTGTATGCAACCTGCCTTTTATCTTAA
CAAGCGTCTTATTCCGCTTGAATCCTTATGCACTCATTATTATTGGCCTAGTCTTTATCGCATGCTATTTAATGGGCTAT
TTTTATTTAAACAGGCAAGTTTGTGCCCTAGAAAAACGAGCATCTTAA

Upstream 100 bases:

>100_bases
TTGAAATTGTAACACAAAAACCCTCCCTATGTATAAGATTTTATCATCAAGCTATCTTTTGCTATAATAACTGAAGTAAA
AATACTAAATCTAATAAAAA

Downstream 100 bases:

>100_bases
TGAAAAGGCTTAAAGGTCTTTTTTTGAGCTTGCTTTTATGCTTGTATCCTTTAGAGAGCAAGCCTTTGAGTAACGGAGCA
TATGTTTTAGAAGAAATTGG

Product: methicillin resistance protein

Products: UMP; Undecaprenyl N-Acetyl-Alpha-D-Glucosaminyl Pyrophosphate. [C]

Alternate protein names: UDP-GlcNAc:undecaprenyl-phosphate GlcNAc-1-phosphate transferase; Undecaprenyl-Phosphate GlcNAc-1-phosphate transferase [H]

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MLWVLYFLTSLFICSLIVLWSKKSTLFVDNANKIQGFHHARTPRAGGLGIFLSFVLACFFEPLEMPFKGSFVFLGLLLVF
LSGFLEDINLSLSPKTRLILQGIGVVCIISSTPLVVSDFSPLFSLPYFIAFLFAIFMLVGISNAINIIDGFNGLASGICT
ITLLIVHYIEPNGPSCLLAYMVLGFMVLNFPLGKIFLGDGGAYFLGLACGISLLYLSLEQKISVFFGLNLMLYPIIEVLF
SILRRKIKRQKATMPDNLHLHTLLFKFLQRRSLGYPNSLCAFIIIVCNLPFILTSVLFRLNPYALIIIGLVFIACYLMGY
FYLNRQVCALEKRAS

Sequences:

>Translated_335_residues
MLWVLYFLTSLFICSLIVLWSKKSTLFVDNANKIQGFHHARTPRAGGLGIFLSFVLACFFEPLEMPFKGSFVFLGLLLVF
LSGFLEDINLSLSPKTRLILQGIGVVCIISSTPLVVSDFSPLFSLPYFIAFLFAIFMLVGISNAINIIDGFNGLASGICT
ITLLIVHYIEPNGPSCLLAYMVLGFMVLNFPLGKIFLGDGGAYFLGLACGISLLYLSLEQKISVFFGLNLMLYPIIEVLF
SILRRKIKRQKATMPDNLHLHTLLFKFLQRRSLGYPNSLCAFIIIVCNLPFILTSVLFRLNPYALIIIGLVFIACYLMGY
FYLNRQVCALEKRAS
>Mature_335_residues
MLWVLYFLTSLFICSLIVLWSKKSTLFVDNANKIQGFHHARTPRAGGLGIFLSFVLACFFEPLEMPFKGSFVFLGLLLVF
LSGFLEDINLSLSPKTRLILQGIGVVCIISSTPLVVSDFSPLFSLPYFIAFLFAIFMLVGISNAINIIDGFNGLASGICT
ITLLIVHYIEPNGPSCLLAYMVLGFMVLNFPLGKIFLGDGGAYFLGLACGISLLYLSLEQKISVFFGLNLMLYPIIEVLF
SILRRKIKRQKATMPDNLHLHTLLFKFLQRRSLGYPNSLCAFIIIVCNLPFILTSVLFRLNPYALIIIGLVFIACYLMGY
FYLNRQVCALEKRAS

Specific function: Catalyzes the formation of undecaprenyl-PP-N- acetylglucosamine. Involved in the synthesis of anionic cell-wall polymers as it mediates the initiation of the linkage unit formation that appears to be common to the two types of teichoic acids attached to t

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4 [H]

EC number: 2.7.8.- [C]

Molecular weight: Translated: 37462; Mature: 37462

Theoretical pI: Translated: 9.09; Mature: 9.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLWVLYFLTSLFICSLIVLWSKKSTLFVDNANKIQGFHHARTPRAGGLGIFLSFVLACFF
CEEHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHCCHHHCCCCCCCCHHHHHHHHHHHHH
EPLEMPFKGSFVFLGLLLVFLSGFLEDINLSLSPKTRLILQGIGVVCIISSTPLVVSDFS
HHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCEEEEECCCCEEEECCC
PLFSLPYFIAFLFAIFMLVGISNAINIIDGFNGLASGICTITLLIVHYIEPNGPSCLLAY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
MVLGFMVLNFPLGKIFLGDGGAYFLGLACGISLLYLSLEQKISVFFGLNLMLYPIIEVLF
HHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SILRRKIKRQKATMPDNLHLHTLLFKFLQRRSLGYPNSLCAFIIIVCNLPFILTSVLFRL
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHH
NPYALIIIGLVFIACYLMGYFYLNRQVCALEKRAS
CCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCC
>Mature Secondary Structure
MLWVLYFLTSLFICSLIVLWSKKSTLFVDNANKIQGFHHARTPRAGGLGIFLSFVLACFF
CEEHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHCCHHHCCCCCCCCHHHHHHHHHHHHH
EPLEMPFKGSFVFLGLLLVFLSGFLEDINLSLSPKTRLILQGIGVVCIISSTPLVVSDFS
HHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCEEEEECCCCEEEECCC
PLFSLPYFIAFLFAIFMLVGISNAINIIDGFNGLASGICTITLLIVHYIEPNGPSCLLAY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
MVLGFMVLNFPLGKIFLGDGGAYFLGLACGISLLYLSLEQKISVFFGLNLMLYPIIEVLF
HHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SILRRKIKRQKATMPDNLHLHTLLFKFLQRRSLGYPNSLCAFIIIVCNLPFILTSVLFRL
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHH
NPYALIIIGLVFIACYLMGYFYLNRQVCALEKRAS
CCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: UDP-N-Acetyl-D-Glucosamine; Undecaprenyl Phosphate [C]

Specific reaction: UDP-N-Acetyl-D-Glucosamine + Undecaprenyl Phosphate = UMP + Undecaprenyl N-Acetyl-Alpha-D-Glucosaminyl Pyrophosphate. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12101296; 9384377 [H]