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The map label for this gene is metB [H]

Identifier: 108813899

GI number: 108813899

Start: 4291447

End: 4291590

Strand: Reverse

Name: metB [H]

Synonym: YPN_3739

Alternate gene names: 108813899

Gene position: 4291590-4291447 (Counterclockwise)

Preceding gene: 108813900

Following gene: 108813898

Centisome position: 94.64

GC content: 50.0

Gene sequence:

>144_bases
ATGACCCACGCGGGTATGGCGGCAGAGGCGCGTATTGCCGCAGGCATTACTGATAGTTTGTTGCGTATTTCCGTGGGTAT
TGAAGACAGTGAAGATTTGATTGCTGATTTGGACCACGCGTTCCAATTGGCAGTAACGAGGTAA

Upstream 100 bases:

>100_bases
GTGATGAGCAGGTCATGCGCCGTTTCCTTTCTGCCCTTGAGCTATTTACCTTGGCAGAGTCTTTGGGGGGGTAGAAAGCC
TGATCTCCCATGCAGCGACC

Downstream 100 bases:

>100_bases
GCATGAATGCAACAGCGGTAGCAGCGGCGGCAACGGGCCGTCAACTGCATAAATTTGGTGGCAGTAGCCTTGCGGATGTG
AAGTGTTATCTACGGGTGGC

Product: cystathionine gamma-synthase

Products: NA

Alternate protein names: CGS; O-succinylhomoserine (thiol)-lyase [H]

Number of amino acids: Translated: 47; Mature: 46

Protein sequence:

>47_residues
MTHAGMAAEARIAAGITDSLLRISVGIEDSEDLIADLDHAFQLAVTR

Sequences:

>Translated_47_residues
MTHAGMAAEARIAAGITDSLLRISVGIEDSEDLIADLDHAFQLAVTR
>Mature_46_residues
THAGMAAEARIAAGITDSLLRISVGIEDSEDLIADLDHAFQLAVTR

Specific function: Methionine biosynthesis; second step. [C]

COG id: COG0626

COG function: function code E; Cystathionine beta-lyases/cystathionine gamma-synthases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trans-sulfuration enzymes family [H]

Homologues:

Organism=Escherichia coli, GI1790375, Length=44, Percent_Identity=72.7272727272727, Blast_Score=67, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000277
- InterPro:   IPR011821
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01053 Cys_Met_Meta_PP [H]

EC number: =2.5.1.48 [H]

Molecular weight: Translated: 4967; Mature: 4835

Theoretical pI: Translated: 4.24; Mature: 4.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHAGMAAEARIAAGITDSLLRISVGIEDSEDLIADLDHAFQLAVTR
CCCCCCCCCCHHHCCCCCCEEEEECCCCCCHHHHHHHCCCEEEEECC
>Mature Secondary Structure 
THAGMAAEARIAAGITDSLLRISVGIEDSEDLIADLDHAFQLAVTR
CCCCCCCCCHHHCCCCCCEEEEECCCCCCHHHHHHHCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6361020; 8346018; 9278503; 3307782; 9843488 [H]