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The map label for this gene is ycaD [C]

Identifier: 108812758

GI number: 108812758

Start: 2928353

End: 2928916

Strand: Reverse

Name: ycaD [C]

Synonym: YPN_2597

Alternate gene names: 108812758

Gene position: 2928916-2928353 (Counterclockwise)

Preceding gene: 108812761

Following gene: 108812756

Centisome position: 64.59

GC content: 50.18

Gene sequence:

>564_bases
ATGTTAAAACGCCGCAGCGCCCGTTTAGGTATTAATGGATGTATTATCTCTGGTGTACTCTTGGGGTCACTCTATGGGTT
ACTGCCACTGTATTTATCCCATAAGGGGATGAGTGACGCCAGCGTGGGGGGGTGGATGGCGTTGCTGGTCAGTTCAGGGA
TTATTGGGCAATGGCCTATGGGAAGAATGGCTGACCGCTATGGCCGCTTACTGGTACTGCGGATCCAAGTGTTTGTCGTC
ATCCTCGGTAGTGTGGCGATCTTGGGTAATTACGCAATGGCGCCGGCGTTATTCATTTTAGGCTGCGCGGGTTTCACTTT
GTATCCGGTTGCTATGGCCTGGGCGTGTGAAAAAGCCAGCGCTGATGAATTGGTCGCGATGAATCAGGCGTTACTGATGA
GTTATACCCTTGGGAGCCTGGCCGGGCCGACGATGACGTCACTGCTGATGCAGCGCTATTCAGATAATTTATTATTTATC
ATGATAGCAGGTGTCGCATTCGTGTATTTGATGATGCTGTTGAGAAAGCCAGATCACCAACAAACGCCTTATGCTGCGGT
ATAA

Upstream 100 bases:

>100_bases
ACCCCCTGGATCTGATTTCAGGCGTTGGGTGTGGATCACTATTGCACCGTTCGTTACACATCAAAGTCGTCACGAGTCAC
CGCCTATTGCGGTTTGGCCT

Downstream 100 bases:

>100_bases
AAGTAAGCCGTATCAATATAAAACGGTATCAATATATAAGACAACGCCGCCAGCGGATTCATCCAGCATGGCGGCAGTTG
TTAGGCCAAACCTAATACAC

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 187; Mature: 187

Protein sequence:

>187_residues
MLKRRSARLGINGCIISGVLLGSLYGLLPLYLSHKGMSDASVGGWMALLVSSGIIGQWPMGRMADRYGRLLVLRIQVFVV
ILGSVAILGNYAMAPALFILGCAGFTLYPVAMAWACEKASADELVAMNQALLMSYTLGSLAGPTMTSLLMQRYSDNLLFI
MIAGVAFVYLMMLLRKPDHQQTPYAAV

Sequences:

>Translated_187_residues
MLKRRSARLGINGCIISGVLLGSLYGLLPLYLSHKGMSDASVGGWMALLVSSGIIGQWPMGRMADRYGRLLVLRIQVFVV
ILGSVAILGNYAMAPALFILGCAGFTLYPVAMAWACEKASADELVAMNQALLMSYTLGSLAGPTMTSLLMQRYSDNLLFI
MIAGVAFVYLMMLLRKPDHQQTPYAAV
>Mature_187_residues
MLKRRSARLGINGCIISGVLLGSLYGLLPLYLSHKGMSDASVGGWMALLVSSGIIGQWPMGRMADRYGRLLVLRIQVFVV
ILGSVAILGNYAMAPALFILGCAGFTLYPVAMAWACEKASADELVAMNQALLMSYTLGSLAGPTMTSLLMQRYSDNLLFI
MIAGVAFVYLMMLLRKPDHQQTPYAAV

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. YcaD (TC 2.A.1.26) family

Homologues:

Organism=Escherichia coli, GI1787126, Length=187, Percent_Identity=72.7272727272727, Blast_Score=286, Evalue=5e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1380_YERPE (Q8ZGC3)

Other databases:

- EMBL:   AL590842
- EMBL:   AE009952
- EMBL:   AE017042
- PIR:   AF0168
- RefSeq:   NP_992579.1
- RefSeq:   YP_002346403.1
- ProteinModelPortal:   Q8ZGC3
- GeneID:   1174221
- GeneID:   2764830
- GenomeReviews:   AE017042_GR
- GenomeReviews:   AL590842_GR
- KEGG:   ype:YPO1380
- KEGG:   ypm:YP_1213
- HOGENOM:   HBG302458
- OMA:   TISIFAT
- ProtClustDB:   PRK03633
- BioCyc:   YPES214092:YPO1380-MONOMER
- HAMAP:   MF_01149
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196

Pfam domain/function: PF07690 MFS_1; SSF103473 MFS_gen_substrate_transporter

EC number: NA

Molecular weight: Translated: 20202; Mature: 20202

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x12420a60)-; HASH(0x1212dd7c)-; HASH(0x11aff56c)-; HASH(0x119bbc00)-; HASH(0x12577ffc)-; HASH(0x12247000)-; HASH(0x12407460)-; HASH(0x1248255c)-; HASH(0xbf76864)-; HASH(0x11dd465c)-; HASH(0x122da464)-; HASH(0x11a65488)-;

Cys/Met content:

1.6 %Cys     (Translated Protein)
7.5 %Met     (Translated Protein)
9.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
7.5 %Met     (Mature Protein)
9.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKRRSARLGINGCIISGVLLGSLYGLLPLYLSHKGMSDASVGGWMALLVSSGIIGQWPM
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCC
GRMADRYGRLLVLRIQVFVVILGSVAILGNYAMAPALFILGCAGFTLYPVAMAWACEKAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCC
ADELVAMNQALLMSYTLGSLAGPTMTSLLMQRYSDNLLFIMIAGVAFVYLMMLLRKPDHQ
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCC
QTPYAAV
CCCCCCH
>Mature Secondary Structure
MLKRRSARLGINGCIISGVLLGSLYGLLPLYLSHKGMSDASVGGWMALLVSSGIIGQWPM
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCC
GRMADRYGRLLVLRIQVFVVILGSVAILGNYAMAPALFILGCAGFTLYPVAMAWACEKAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCC
ADELVAMNQALLMSYTLGSLAGPTMTSLLMQRYSDNLLFIMIAGVAFVYLMMLLRKPDHQ
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCC
QTPYAAV
CCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430