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The map label for this gene is dcuB [H]

Identifier: 108810974

GI number: 108810974

Start: 939591

End: 939887

Strand: Reverse

Name: dcuB [H]

Synonym: YPN_0809

Alternate gene names: 108810974

Gene position: 939887-939591 (Counterclockwise)

Preceding gene: 108810975

Following gene: 108810973

Centisome position: 20.73

GC content: 47.81

Gene sequence:

>297_bases
GTGCTGTTCTTAGTCTCGAAGCTGGTGAACAGCCAAGCCGCGGCGCTAGCAGCGATCGCACCAATGGGCTTACAATTAGG
CGTTGAACCTAAGATGCTCATCGCATTTTTCCCAGCAGCTTACGGATATTTTGTTCTGCCAACCTACCCGAGTGATCTGG
CTTGTATCGGTTTTGACCGCTCTGGTACCACCAAAATTGGTAGATTCATTATCAACCATAGCTTTATCATTCCAGGTCTT
ATTGGCGTCATTTGCTCCTGTATCACGGGCTATCTGCTGGTAACGACGTTTATGTAG

Upstream 100 bases:

>100_bases
GCGTTGCCTGGATGAGTGACACCTTCTTCCAGGCTCATATGGGTGAACTGAGATTAGTACTGGAAGATGTGGTAAAAGCC
ACCCTTGGACTTATGCCATT

Downstream 100 bases:

>100_bases
TGAATCATAAATCCAGGAGTCTACTTTGTAGGGCCAGTGTATTTTCTGGCTCTTAATCCCCTTCTAATTTGACGCTGCCA
CAGTATTAATGGCATTCATT

Product: Dcu family anaerobic C4-dicarboxylate transporter

Products: C4-dicarboxylates [Periplasm]; C4-dicarboxylates [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 98; Mature: 98

Protein sequence:

>98_residues
MLFLVSKLVNSQAAALAAIAPMGLQLGVEPKMLIAFFPAAYGYFVLPTYPSDLACIGFDRSGTTKIGRFIINHSFIIPGL
IGVICSCITGYLLVTTFM

Sequences:

>Translated_98_residues
MLFLVSKLVNSQAAALAAIAPMGLQLGVEPKMLIAFFPAAYGYFVLPTYPSDLACIGFDRSGTTKIGRFIINHSFIIPGL
IGVICSCITGYLLVTTFM
>Mature_98_residues
MLFLVSKLVNSQAAALAAIAPMGLQLGVEPKMLIAFFPAAYGYFVLPTYPSDLACIGFDRSGTTKIGRFIINHSFIIPGL
IGVICSCITGYLLVTTFM

Specific function: Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane [H]

COG id: COG2704

COG function: function code R; Anaerobic C4-dicarboxylate transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dcuA/dcuB transporter (TC 2.A.13.1) family [H]

Homologues:

Organism=Escherichia coli, GI1790565, Length=97, Percent_Identity=64.9484536082474, Blast_Score=134, Evalue=1e-33,
Organism=Escherichia coli, GI1790580, Length=91, Percent_Identity=46.1538461538462, Blast_Score=85, Evalue=8e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004668 [H]

Pfam domain/function: PF03605 DcuA_DcuB [H]

EC number: NA

Molecular weight: Translated: 10494; Mature: 10494

Theoretical pI: Translated: 8.48; Mature: 8.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFLVSKLVNSQAAALAAIAPMGLQLGVEPKMLIAFFPAAYGYFVLPTYPSDLACIGFDR
CHHHHHHHHCHHHHHHHHHHCCCCEECCCCHHHEEEHHHHCCEEEECCCCCCEEEEEECC
SGTTKIGRFIINHSFIIPGLIGVICSCITGYLLVTTFM
CCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLFLVSKLVNSQAAALAAIAPMGLQLGVEPKMLIAFFPAAYGYFVLPTYPSDLACIGFDR
CHHHHHHHHCHHHHHHHHHHCCCCEECCCCHHHEEEHHHHCCEEEECCCCCCEEEEEECC
SGTTKIGRFIINHSFIIPGLIGVICSCITGYLLVTTFM
CCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: C4-dicarboxylates [Periplasm]; C4-dicarboxylates [Periplasm] [C]

Specific reaction: C4-dicarboxylates [Periplasm] + C4-dicarboxylates [Periplasm] = C4-dicarboxylates [Periplasm] + C4-dicarboxylates [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]