| Definition | Mycobacterium sp. MCS chromosome, complete genome. |
|---|---|
| Accession | NC_008146 |
| Length | 5,705,448 |
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The map label for this gene is fabG [H]
Identifier: 108801900
GI number: 108801900
Start: 5226959
End: 5227702
Strand: Reverse
Name: fabG [H]
Synonym: Mmcs_4937
Alternate gene names: 108801900
Gene position: 5227702-5226959 (Counterclockwise)
Preceding gene: 108801901
Following gene: 108801899
Centisome position: 91.63
GC content: 69.62
Gene sequence:
>744_bases GTGAGTCGAGTAGCGGTGGTGACCGGCGGCGCGTCGGGCCTGGGCGAGGCGATCTGCGCCGGGCTGGCCGCTGACGGCCA TCGGGTCGCCGTCCTGGACGTCGACCTCGGTGCGGCCGAGAAACTTGCCGCCGGGTTGCGCGAACGCGGGGCGCACGCGA TGGCCGTGCAGGCCGACGTCTCCGAGGAACCGTCGGTCGAGTCGGCATTCGCCGCGGTACGAGCCGAATTCGGCCCGGTC GGGATTCTCGTGACCAGCGCAGCGATCGGCGGCTTCACCCGCTTCGACAAGATCACCCTCGACGAATGGAACCGCTACCT CGCGGTGAACCTCACCGGCACGTTCCTGAGTATCCGGTCCGCGCTCGGCGACATGGTCGCGGCGAAATGGGGTCGGGTCG TGACGATTTCGTCGGCCGCGGGTCAACAGGGCGCGCCGCGACAGGGACACTATTCGGCCACCAAGGGCGGCGTCATCGCA CTGACCAAGACGGTGGCCCGCGACTACGCCCGCCACGGAGTCACCGCGAACTCCGTCCCCCCGTTCGCGATCGAGACCCC GATGCTTCGCCGACAGCAGGCCGAAGGCAAACTCCCGCCCGCCGAATACCTGACGCAGGCGATCCCGGCGGGCCGGGTGG GCGCCCCCGAGGACGTGGCCGCAGTGTGTTCGTTCCTGTGTTCGGAGGCCGCCGGCTACGTCACCGGTCAGGTCATCGGC GTCAACGGAGGGGCAGTGATGTGA
Upstream 100 bases:
>100_bases GATCATGGCAATGGCCTGGCGGGCAGCGGATTTCATCCTGCACGGGTGCTGAACCGGCCGTGTGTGCTATACATTTGTAT AGCGGTGGCGAGGAGTAGTG
Downstream 100 bases:
>100_bases GTACCCGACCCGACCAGGCGGTGAGCTACCACTTCGACCGGCACAGCCAGGACTACCGCGAGCGGTTTCTCGACATCACC CACGAGATGCACCGGAAGTG
Product: short-chain dehydrogenase/reductase SDR
Products: NA
Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]
Number of amino acids: Translated: 247; Mature: 246
Protein sequence:
>247_residues MSRVAVVTGGASGLGEAICAGLAADGHRVAVLDVDLGAAEKLAAGLRERGAHAMAVQADVSEEPSVESAFAAVRAEFGPV GILVTSAAIGGFTRFDKITLDEWNRYLAVNLTGTFLSIRSALGDMVAAKWGRVVTISSAAGQQGAPRQGHYSATKGGVIA LTKTVARDYARHGVTANSVPPFAIETPMLRRQQAEGKLPPAEYLTQAIPAGRVGAPEDVAAVCSFLCSEAAGYVTGQVIG VNGGAVM
Sequences:
>Translated_247_residues MSRVAVVTGGASGLGEAICAGLAADGHRVAVLDVDLGAAEKLAAGLRERGAHAMAVQADVSEEPSVESAFAAVRAEFGPV GILVTSAAIGGFTRFDKITLDEWNRYLAVNLTGTFLSIRSALGDMVAAKWGRVVTISSAAGQQGAPRQGHYSATKGGVIA LTKTVARDYARHGVTANSVPPFAIETPMLRRQQAEGKLPPAEYLTQAIPAGRVGAPEDVAAVCSFLCSEAAGYVTGQVIG VNGGAVM >Mature_246_residues SRVAVVTGGASGLGEAICAGLAADGHRVAVLDVDLGAAEKLAAGLRERGAHAMAVQADVSEEPSVESAFAAVRAEFGPVG ILVTSAAIGGFTRFDKITLDEWNRYLAVNLTGTFLSIRSALGDMVAAKWGRVVTISSAAGQQGAPRQGHYSATKGGVIAL TKTVARDYARHGVTANSVPPFAIETPMLRRQQAEGKLPPAEYLTQAIPAGRVGAPEDVAAVCSFLCSEAAGYVTGQVIGV NGGAVM
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: COG1028
COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI15277342, Length=258, Percent_Identity=40.3100775193798, Blast_Score=154, Evalue=8e-38, Organism=Homo sapiens, GI40254992, Length=244, Percent_Identity=31.5573770491803, Blast_Score=117, Evalue=8e-27, Organism=Homo sapiens, GI19923817, Length=247, Percent_Identity=31.5789473684211, Blast_Score=110, Evalue=1e-24, Organism=Homo sapiens, GI32483357, Length=244, Percent_Identity=29.9180327868852, Blast_Score=101, Evalue=6e-22, Organism=Homo sapiens, GI4758504, Length=259, Percent_Identity=30.8880308880309, Blast_Score=100, Evalue=1e-21, Organism=Homo sapiens, GI83715985, Length=259, Percent_Identity=30.5019305019305, Blast_Score=92, Evalue=5e-19, Organism=Homo sapiens, GI66933014, Length=147, Percent_Identity=34.6938775510204, Blast_Score=91, Evalue=1e-18, Organism=Homo sapiens, GI4504505, Length=238, Percent_Identity=31.0924369747899, Blast_Score=86, Evalue=3e-17, Organism=Homo sapiens, GI5031737, Length=243, Percent_Identity=30.0411522633745, Blast_Score=85, Evalue=7e-17, Organism=Homo sapiens, GI126723750, Length=247, Percent_Identity=27.9352226720648, Blast_Score=82, Evalue=4e-16, Organism=Homo sapiens, GI7705925, Length=247, Percent_Identity=29.1497975708502, Blast_Score=81, Evalue=1e-15, Organism=Homo sapiens, GI31542939, Length=204, Percent_Identity=27.4509803921569, Blast_Score=79, Evalue=4e-15, Organism=Homo sapiens, GI59889578, Length=225, Percent_Identity=31.5555555555556, Blast_Score=78, Evalue=6e-15, Organism=Homo sapiens, GI10190704, Length=251, Percent_Identity=29.0836653386454, Blast_Score=78, Evalue=8e-15, Organism=Homo sapiens, GI4503301, Length=218, Percent_Identity=24.7706422018349, Blast_Score=71, Evalue=7e-13, Organism=Homo sapiens, GI224922801, Length=170, Percent_Identity=28.8235294117647, Blast_Score=71, Evalue=9e-13, Organism=Homo sapiens, GI4503817, Length=224, Percent_Identity=26.3392857142857, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI109715829, Length=248, Percent_Identity=26.2096774193548, Blast_Score=65, Evalue=4e-11, Organism=Escherichia coli, GI1787335, Length=245, Percent_Identity=35.5102040816327, Blast_Score=145, Evalue=3e-36, Organism=Escherichia coli, GI1789057, Length=258, Percent_Identity=35.2713178294574, Blast_Score=124, Evalue=5e-30, Organism=Escherichia coli, GI87082100, Length=250, Percent_Identity=31.2, Blast_Score=122, Evalue=2e-29, Organism=Escherichia coli, GI1790717, Length=242, Percent_Identity=28.9256198347107, Blast_Score=118, Evalue=3e-28, Organism=Escherichia coli, GI2367175, Length=249, Percent_Identity=34.9397590361446, Blast_Score=113, Evalue=1e-26, Organism=Escherichia coli, GI1788459, Length=251, Percent_Identity=32.2709163346614, Blast_Score=112, Evalue=3e-26, Organism=Escherichia coli, GI1789208, Length=245, Percent_Identity=30.2040816326531, Blast_Score=106, Evalue=2e-24, Organism=Escherichia coli, GI87082160, Length=249, Percent_Identity=27.710843373494, Blast_Score=96, Evalue=2e-21, Organism=Escherichia coli, GI1787905, Length=246, Percent_Identity=28.0487804878049, Blast_Score=94, Evalue=9e-21, Organism=Escherichia coli, GI1789378, Length=247, Percent_Identity=28.3400809716599, Blast_Score=85, Evalue=5e-18, Organism=Escherichia coli, GI1786812, Length=252, Percent_Identity=27.3809523809524, Blast_Score=73, Evalue=1e-14, Organism=Escherichia coli, GI2367365, Length=244, Percent_Identity=27.8688524590164, Blast_Score=68, Evalue=7e-13, Organism=Caenorhabditis elegans, GI25147288, Length=249, Percent_Identity=36.144578313253, Blast_Score=125, Evalue=1e-29, Organism=Caenorhabditis elegans, GI17555706, Length=246, Percent_Identity=34.5528455284553, Blast_Score=124, Evalue=5e-29, Organism=Caenorhabditis elegans, GI17560676, Length=246, Percent_Identity=30.4878048780488, Blast_Score=103, Evalue=8e-23, Organism=Caenorhabditis elegans, GI17538182, Length=257, Percent_Identity=31.1284046692607, Blast_Score=100, Evalue=9e-22, Organism=Caenorhabditis elegans, GI17562906, Length=259, Percent_Identity=26.6409266409266, Blast_Score=87, Evalue=8e-18, Organism=Caenorhabditis elegans, GI17536651, Length=250, Percent_Identity=28, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17536025, Length=247, Percent_Identity=28.3400809716599, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI17559104, Length=261, Percent_Identity=25.2873563218391, Blast_Score=85, Evalue=4e-17, Organism=Caenorhabditis elegans, GI17560332, Length=266, Percent_Identity=28.5714285714286, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17562908, Length=261, Percent_Identity=26.8199233716475, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17531453, Length=258, Percent_Identity=26.3565891472868, Blast_Score=81, Evalue=4e-16, Organism=Caenorhabditis elegans, GI17561272, Length=247, Percent_Identity=30.3643724696356, Blast_Score=80, Evalue=9e-16, Organism=Caenorhabditis elegans, GI17567345, Length=190, Percent_Identity=27.8947368421053, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI71994604, Length=247, Percent_Identity=26.3157894736842, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17562910, Length=259, Percent_Identity=25.8687258687259, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17562904, Length=262, Percent_Identity=27.0992366412214, Blast_Score=77, Evalue=9e-15, Organism=Caenorhabditis elegans, GI17561402, Length=245, Percent_Identity=23.6734693877551, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17563726, Length=265, Percent_Identity=27.1698113207547, Blast_Score=76, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17508895, Length=215, Percent_Identity=24.6511627906977, Blast_Score=75, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17568967, Length=193, Percent_Identity=29.5336787564767, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI72000259, Length=258, Percent_Identity=25.968992248062, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI17538486, Length=267, Percent_Identity=25.8426966292135, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI17562990, Length=257, Percent_Identity=26.4591439688716, Blast_Score=74, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17508651, Length=248, Percent_Identity=27.8225806451613, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI17560150, Length=260, Percent_Identity=25.3846153846154, Blast_Score=71, Evalue=5e-13, Organism=Caenorhabditis elegans, GI17564282, Length=193, Percent_Identity=27.979274611399, Blast_Score=71, Evalue=6e-13, Organism=Caenorhabditis elegans, GI193203115, Length=189, Percent_Identity=26.984126984127, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI193203117, Length=189, Percent_Identity=26.984126984127, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17544670, Length=262, Percent_Identity=23.6641221374046, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI71994600, Length=248, Percent_Identity=25.8064516129032, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI193204405, Length=264, Percent_Identity=23.4848484848485, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI115534694, Length=248, Percent_Identity=26.6129032258064, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17560220, Length=262, Percent_Identity=25.5725190839695, Blast_Score=67, Evalue=9e-12, Organism=Caenorhabditis elegans, GI17538480, Length=264, Percent_Identity=23.4848484848485, Blast_Score=66, Evalue=1e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=209, Percent_Identity=33.0143540669856, Blast_Score=93, Evalue=3e-20, Organism=Saccharomyces cerevisiae, GI6324126, Length=250, Percent_Identity=29.6, Blast_Score=92, Evalue=7e-20, Organism=Drosophila melanogaster, GI24639444, Length=250, Percent_Identity=34.4, Blast_Score=124, Evalue=5e-29, Organism=Drosophila melanogaster, GI21355319, Length=246, Percent_Identity=33.3333333333333, Blast_Score=114, Evalue=5e-26, Organism=Drosophila melanogaster, GI21357041, Length=251, Percent_Identity=30.6772908366534, Blast_Score=95, Evalue=5e-20, Organism=Drosophila melanogaster, GI23397609, Length=248, Percent_Identity=31.0483870967742, Blast_Score=93, Evalue=1e-19, Organism=Drosophila melanogaster, GI17737361, Length=260, Percent_Identity=30.3846153846154, Blast_Score=91, Evalue=5e-19, Organism=Drosophila melanogaster, GI28571526, Length=252, Percent_Identity=28.5714285714286, Blast_Score=86, Evalue=3e-17, Organism=Drosophila melanogaster, GI21355631, Length=157, Percent_Identity=35.6687898089172, Blast_Score=84, Evalue=9e-17, Organism=Drosophila melanogaster, GI18859837, Length=240, Percent_Identity=32.5, Blast_Score=81, Evalue=5e-16, Organism=Drosophila melanogaster, GI24644339, Length=245, Percent_Identity=27.3469387755102, Blast_Score=79, Evalue=2e-15, Organism=Drosophila melanogaster, GI221331218, Length=194, Percent_Identity=34.020618556701, Blast_Score=74, Evalue=1e-13, Organism=Drosophila melanogaster, GI21356301, Length=214, Percent_Identity=28.5046728971963, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI24665243, Length=194, Percent_Identity=34.020618556701, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI24649181, Length=163, Percent_Identity=32.5153374233129, Blast_Score=72, Evalue=3e-13, Organism=Drosophila melanogaster, GI221331216, Length=195, Percent_Identity=33.8461538461538, Blast_Score=70, Evalue=9e-13, Organism=Drosophila melanogaster, GI24665247, Length=195, Percent_Identity=33.8461538461538, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI24643142, Length=244, Percent_Identity=26.6393442622951, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI24644337, Length=201, Percent_Identity=28.3582089552239, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI116007236, Length=198, Percent_Identity=29.7979797979798, Blast_Score=65, Evalue=5e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011284 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.100 [H]
Molecular weight: Translated: 25235; Mature: 25104
Theoretical pI: Translated: 6.93; Mature: 6.93
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.2 %Cys (Translated Protein) 2.0 %Met (Translated Protein) 3.2 %Cys+Met (Translated Protein) 1.2 %Cys (Mature Protein) 1.6 %Met (Mature Protein) 2.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSRVAVVTGGASGLGEAICAGLAADGHRVAVLDVDLGAAEKLAAGLRERGAHAMAVQADV CCEEEEEECCCCHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHCCCEEEEEEECC SEEPSVESAFAAVRAEFGPVGILVTSAAIGGFTRFDKITLDEWNRYLAVNLTGTFLSIRS CCCCCHHHHHHHHHHCCCCEEEEEEHHHHCCHHHHCEEECCCCCCEEEEEECHHHHHHHH ALGDMVAAKWGRVVTISSAAGQQGAPRQGHYSATKGGVIALTKTVARDYARHGVTANSVP HHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHCCCCCCCC PFAIETPMLRRQQAEGKLPPAEYLTQAIPAGRVGAPEDVAAVCSFLCSEAAGYVTGQVIG CCEECCHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEE VNGGAVM CCCCCCC >Mature Secondary Structure SRVAVVTGGASGLGEAICAGLAADGHRVAVLDVDLGAAEKLAAGLRERGAHAMAVQADV CEEEEEECCCCHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHCCCEEEEEEECC SEEPSVESAFAAVRAEFGPVGILVTSAAIGGFTRFDKITLDEWNRYLAVNLTGTFLSIRS CCCCCHHHHHHHHHHCCCCEEEEEEHHHHCCHHHHCEEECCCCCCEEEEEECHHHHHHHH ALGDMVAAKWGRVVTISSAAGQQGAPRQGHYSATKGGVIALTKTVARDYARHGVTANSVP HHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHCCCCCCCC PFAIETPMLRRQQAEGKLPPAEYLTQAIPAGRVGAPEDVAAVCSFLCSEAAGYVTGQVIG CCEECCHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEE VNGGAVM CCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9537320 [H]