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The map label for this gene is 108801830

Identifier: 108801830

GI number: 108801830

Start: 5155800

End: 5157155

Strand: Reverse

Name: 108801830

Synonym: Mmcs_4867

Alternate gene names: NA

Gene position: 5157155-5155800 (Counterclockwise)

Preceding gene: 108801836

Following gene: 161407219

Centisome position: 90.39

GC content: 67.77

Gene sequence:

>1356_bases
ATGACCGAGACCGACCACGCGCGCGACGCCGTCAGCGCCGACAACCTGCCGTCGGGAGGCGAGTTCTTCCACAAGGGCAA
CTACGCGCCCGTCGCCGACGAACTCACCGCCTTCGACCTGCCCGTCGAGGGGCAGATCCCGGCCGATCTGCAGGGGTGGT
ACCTGCGCAACGGTCCGAACCCGCGGCAGCCGTCCGCGCACTGGTTCACCGGCGACGGCATGATCCACGGCGTGCGCATC
GAGAACGGCCGCGCCGCCTGGTACCGCAACCGGTGGGTGCGCACGGAGAGCTTCGAGCAGCACTTCCCGGTCTACAACTC
CGACGGCAGCCGCAACCTGCACTCCAGCGTCGCCAACACCCACGTCGTCAACCACGCAGGCAAGACCCTGGCGCTCGTCG
AATCGTCGCTGCCCTACGAGATCACCAACGACCTGCAGACCGTGGGCGCCTACGACTTCGGGGGCAAGCTGGTCGACTCG
ATGACGGCGCACCCGAAGATCTGTCCGACCACCGGCGAGTTGCACTTCTTCGGCTACGGCAACCTCTTCGAGCCCTACGT
GACCTATCACCGGGCCGCCGCCGACGGCGAACTGACCGTCAACCGGCCGTTGGACGTCAAGGCGCTGACGATGATGCACG
ACTTCGCGATGACCAGCGGGCACGTGGTCTTCATGGACCTGCCGATCGTCTTCGACATGGGCATCGCGCTCGAGGGCAAG
GGTGACATGCCCTACCGCTGGGACGACGACTACGGCGCCCGCCTCGGCGTACTGCGCCGCGACGATCCCTTCGGCGAGGT
GCGCTGGTTCGACATCGACCCGTGCTACGTCTTCCACGTCGCCAACGCCTACGAGGACGGGAACACGCTGGTGCTGCAGG
CCGTGCGCTACCCCGAACTGTGGCGCGGCACAGGCGGATTCGAGGCCGAGGGAGTGCTGTGGAGCTGGACCCTCGACCTG
GTGACGGGCACGGTGCGCGAACGCCAGCTCGACGACCGGGCCGTGGAGTTCCCCCGCATCGACGACCGGTTGGCGGGTCT
GGCGGCCCGGTACGCGGTGTCTGTGGGCGATCAGCGGTTGGTGCGCTACGACCTGACGAGCGGTACGGCGGTCGAACACG
CCTTCGGGACCGCCGACGCGCCGGGCGGACCCGGCGAGGCGGTGTTCGTGCCGGCCACCTCGGGACCCGTCGACGAACAG
AACGGGTGGTATATGGCGTACGTCTACGACCCGCAGCGCGACGGCAGCGATCTGGTGATCCTCGACGCCGCCGACTTCGC
CGGCCAGCCGGTCGCGAGAATCAAATTGCCGCAACGGGTTCCGTACGGTTTCCACGGCAATTGGATCACCGGATAG

Upstream 100 bases:

>100_bases
GGCCTGCGTGCGCCCACGTTCCAGATATTCCACTATTGACATGTCACTCTTGGACTGTCAGGGTGGTGGCAGACTTTTCC
CTTCAGCCCGAGGAGTCCGC

Downstream 100 bases:

>100_bases
GTCGTCGCCCGCTCGACTATCGCCAACCCGGCCCTTATCGCCGCTGCGGTGCCTACCCTGATGAAATGGGCGTCGAGCGC
AGTGGCGACTCGGACACGGA

Product: carotenoid oxygenase

Products: NA

Alternate protein names: ACO; 8'-apo-beta-carotenal 15,15'-oxygenase; Diox1 [H]

Number of amino acids: Translated: 451; Mature: 450

Protein sequence:

>451_residues
MTETDHARDAVSADNLPSGGEFFHKGNYAPVADELTAFDLPVEGQIPADLQGWYLRNGPNPRQPSAHWFTGDGMIHGVRI
ENGRAAWYRNRWVRTESFEQHFPVYNSDGSRNLHSSVANTHVVNHAGKTLALVESSLPYEITNDLQTVGAYDFGGKLVDS
MTAHPKICPTTGELHFFGYGNLFEPYVTYHRAAADGELTVNRPLDVKALTMMHDFAMTSGHVVFMDLPIVFDMGIALEGK
GDMPYRWDDDYGARLGVLRRDDPFGEVRWFDIDPCYVFHVANAYEDGNTLVLQAVRYPELWRGTGGFEAEGVLWSWTLDL
VTGTVRERQLDDRAVEFPRIDDRLAGLAARYAVSVGDQRLVRYDLTSGTAVEHAFGTADAPGGPGEAVFVPATSGPVDEQ
NGWYMAYVYDPQRDGSDLVILDAADFAGQPVARIKLPQRVPYGFHGNWITG

Sequences:

>Translated_451_residues
MTETDHARDAVSADNLPSGGEFFHKGNYAPVADELTAFDLPVEGQIPADLQGWYLRNGPNPRQPSAHWFTGDGMIHGVRI
ENGRAAWYRNRWVRTESFEQHFPVYNSDGSRNLHSSVANTHVVNHAGKTLALVESSLPYEITNDLQTVGAYDFGGKLVDS
MTAHPKICPTTGELHFFGYGNLFEPYVTYHRAAADGELTVNRPLDVKALTMMHDFAMTSGHVVFMDLPIVFDMGIALEGK
GDMPYRWDDDYGARLGVLRRDDPFGEVRWFDIDPCYVFHVANAYEDGNTLVLQAVRYPELWRGTGGFEAEGVLWSWTLDL
VTGTVRERQLDDRAVEFPRIDDRLAGLAARYAVSVGDQRLVRYDLTSGTAVEHAFGTADAPGGPGEAVFVPATSGPVDEQ
NGWYMAYVYDPQRDGSDLVILDAADFAGQPVARIKLPQRVPYGFHGNWITG
>Mature_450_residues
TETDHARDAVSADNLPSGGEFFHKGNYAPVADELTAFDLPVEGQIPADLQGWYLRNGPNPRQPSAHWFTGDGMIHGVRIE
NGRAAWYRNRWVRTESFEQHFPVYNSDGSRNLHSSVANTHVVNHAGKTLALVESSLPYEITNDLQTVGAYDFGGKLVDSM
TAHPKICPTTGELHFFGYGNLFEPYVTYHRAAADGELTVNRPLDVKALTMMHDFAMTSGHVVFMDLPIVFDMGIALEGKG
DMPYRWDDDYGARLGVLRRDDPFGEVRWFDIDPCYVFHVANAYEDGNTLVLQAVRYPELWRGTGGFEAEGVLWSWTLDLV
TGTVRERQLDDRAVEFPRIDDRLAGLAARYAVSVGDQRLVRYDLTSGTAVEHAFGTADAPGGPGEAVFVPATSGPVDEQN
GWYMAYVYDPQRDGSDLVILDAADFAGQPVARIKLPQRVPYGFHGNWITG

Specific function: Cleaves a number of carotenals and carotenols in the all-trans configuration at the 15-15' double bond producing retinal or retinol, respectively. Also shows activity toward lycopenals and the corresponding alcohols. Does not cleave beta- carotene or lyco

COG id: COG3670

COG function: function code Q; Lignostilbene-alpha,beta-dioxygenase and related enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carotenoid oxygenase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004294 [H]

Pfam domain/function: PF03055 RPE65 [H]

EC number: =1.14.99.41 [H]

Molecular weight: Translated: 50055; Mature: 49924

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTETDHARDAVSADNLPSGGEFFHKGNYAPVADELTAFDLPVEGQIPADLQGWYLRNGPN
CCCCCCCHHCCCCCCCCCCCCCEECCCCCCCCCCCEEECCCCCCCCCCCCCCEEEECCCC
PRQPSAHWFTGDGMIHGVRIENGRAAWYRNRWVRTESFEQHFPVYNSDGSRNLHSSVANT
CCCCCCCEEECCCEEEEEEEECCCEEEECCCEECCCCHHHHCCEECCCCCCHHHHHHHHH
HVVNHAGKTLALVESSLPYEITNDLQTVGAYDFGGKLVDSMTAHPKICPTTGELHFFGYG
HEECCCCCEEEEEECCCCCHHHCCHHHHCCCCCCCHHHHHHCCCCCCCCCCCCEEEEECC
NLFEPYVTYHRAAADGELTVNRPLDVKALTMMHDFAMTSGHVVFMDLPIVFDMGIALEGK
CCCCHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHCCCCEEEEECCEEEECCEEEECC
GDMPYRWDDDYGARLGVLRRDDPFGEVRWFDIDPCYVFHVANAYEDGNTLVLQAVRYPEL
CCCCEEECCCCCCEEEEEECCCCCCCEEEEECCCEEEEEEECCCCCCCEEEEEEECCCHH
WRGTGGFEAEGVLWSWTLDLVTGTVRERQLDDRAVEFPRIDDRLAGLAARYAVSVGDQRL
HCCCCCCCCCCEEEEEEEEHHHHHHHHHHCCCHHCCCCCHHHHHHHHHHHEEEECCCCEE
VRYDLTSGTAVEHAFGTADAPGGPGEAVFVPATSGPVDEQNGWYMAYVYDPQRDGSDLVI
EEEECCCCCEEHHHCCCCCCCCCCCCEEEEECCCCCCCCCCCEEEEEEECCCCCCCCEEE
LDAADFAGQPVARIKLPQRVPYGFHGNWITG
EECCCCCCCCEEEEECCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TETDHARDAVSADNLPSGGEFFHKGNYAPVADELTAFDLPVEGQIPADLQGWYLRNGPN
CCCCCCHHCCCCCCCCCCCCCEECCCCCCCCCCCEEECCCCCCCCCCCCCCEEEECCCC
PRQPSAHWFTGDGMIHGVRIENGRAAWYRNRWVRTESFEQHFPVYNSDGSRNLHSSVANT
CCCCCCCEEECCCEEEEEEEECCCEEEECCCEECCCCHHHHCCEECCCCCCHHHHHHHHH
HVVNHAGKTLALVESSLPYEITNDLQTVGAYDFGGKLVDSMTAHPKICPTTGELHFFGYG
HEECCCCCEEEEEECCCCCHHHCCHHHHCCCCCCCHHHHHHCCCCCCCCCCCCEEEEECC
NLFEPYVTYHRAAADGELTVNRPLDVKALTMMHDFAMTSGHVVFMDLPIVFDMGIALEGK
CCCCHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHCCCCEEEEECCEEEECCEEEECC
GDMPYRWDDDYGARLGVLRRDDPFGEVRWFDIDPCYVFHVANAYEDGNTLVLQAVRYPEL
CCCCEEECCCCCCEEEEEECCCCCCCEEEEECCCEEEEEEECCCCCCCEEEEEEECCCHH
WRGTGGFEAEGVLWSWTLDLVTGTVRERQLDDRAVEFPRIDDRLAGLAARYAVSVGDQRL
HCCCCCCCCCCEEEEEEEEHHHHHHHHHHCCCHHCCCCCHHHHHHHHHHHEEEECCCCEE
VRYDLTSGTAVEHAFGTADAPGGPGEAVFVPATSGPVDEQNGWYMAYVYDPQRDGSDLVI
EEEECCCCCEEHHHCCCCCCCCCCCCEEEEECCCCCCCCCCCEEEEEEECCCCCCCCEEE
LDAADFAGQPVARIKLPQRVPYGFHGNWITG
EECCCCCCCCEEEEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]