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The map label for this gene is panC [H]

Identifier: 108801725

GI number: 108801725

Start: 5039204

End: 5040145

Strand: Reverse

Name: panC [H]

Synonym: Mmcs_4762

Alternate gene names: 108801725

Gene position: 5040145-5039204 (Counterclockwise)

Preceding gene: 108801726

Following gene: 108801724

Centisome position: 88.34

GC content: 68.68

Gene sequence:

>942_bases
ATGACCGCCCGCAGGCCAACCCGATTCGCCAAAGGCGAACTGAACGTCTACCGCGCGCCGCGCGATGTCACCGACGTCAC
GCGCGCGCTGCGCTCCACCGGCAGGCGTGTCGTGCTCGTCCCGACGATGGGCGCGTTGCACGAAGGCCATCTGACTCTGA
TCCGTGCCGCCAAACGGGTGCAGGGCGCCGTCGTCGTCGTGTCGATCTTCGTCAACCCGTTGCAGTTCGGTGCGGGGGAG
GATCTCGACGCGTATCCACGCACACTCGACGACGACCTCGCCGCGCTGCGCGCCGAAGGAGTCGAGATCGCGTTCACGCC
CACGGTCGGCGATATGTACCCCGACGGCACGCGGACCTCGGTGCATCCGGGTCCGCTCGGTGACGATCTCGAAGGTGCTT
CGCGCCCAGGCCATTTCGCGGGTGTGCTCACCGTGGTATGCAAGCTGCTGCACATCGTGCGGCCCGACCGGGCGTTCTTC
GGTGAGAAGGACTACCAGCAGTTGGTGCTGATCCGGCAGATGGTCACCGATCTCAACATCGACACCAAGATCGTCGGCGT
GCCGACGGTCCGTGAGGCCGACGGGCTCGCGCTGTCGTCGCGCAACCGCTACCTCGACGAGGTCGAACGCGAACAGGCCG
GCGCACTGTCGGCCGCCCTGCTGGCCGGGATGTACGCCGCGTCCAACGGTGCGGCCGCCACGCTGGACGCCGCACGCGCC
GTTCTCGACGAGGTCCCCGCCATCGAGGTCGACTACCTGCAGGTCCGCGACCCCATGCTGGGTCCGGTGCCGCACGAGGG
GGCGGCCCGCCTGCTGGTGGCGGCGCGACTCGGCCAGACCAGGCTGCTCGACAACATCGCCGTCGACATCGGCGCATCGG
ACGGTATCGACGGCCACCCCCGGGTCGGTTCGCCCGACCACCAACTGCCCTGGAGGAACTGA

Upstream 100 bases:

>100_bases
TGAATCCCGAACTGGCAGAGGCGTACCGGACGACCTCGCTGCGTACCGCCCAGCGGGCGCACGCATCCGAGGACGTCTTC
GCGGCCCTGGCGGCGCAGTC

Downstream 100 bases:

>100_bases
TGCTTCGCACGATGCTGAAGTCGAAGATCCACCGAGCCACCGTCACGCAGTCCGATCTGCACTACGTCGGCTCGGTCACC
ATCGACGCCGATCTGATGGA

Product: pantoate--beta-alanine ligase

Products: NA

Alternate protein names: PS; Pantoate--beta-alanine ligase; Pantoate-activating enzyme [H]

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MTARRPTRFAKGELNVYRAPRDVTDVTRALRSTGRRVVLVPTMGALHEGHLTLIRAAKRVQGAVVVVSIFVNPLQFGAGE
DLDAYPRTLDDDLAALRAEGVEIAFTPTVGDMYPDGTRTSVHPGPLGDDLEGASRPGHFAGVLTVVCKLLHIVRPDRAFF
GEKDYQQLVLIRQMVTDLNIDTKIVGVPTVREADGLALSSRNRYLDEVEREQAGALSAALLAGMYAASNGAAATLDAARA
VLDEVPAIEVDYLQVRDPMLGPVPHEGAARLLVAARLGQTRLLDNIAVDIGASDGIDGHPRVGSPDHQLPWRN

Sequences:

>Translated_313_residues
MTARRPTRFAKGELNVYRAPRDVTDVTRALRSTGRRVVLVPTMGALHEGHLTLIRAAKRVQGAVVVVSIFVNPLQFGAGE
DLDAYPRTLDDDLAALRAEGVEIAFTPTVGDMYPDGTRTSVHPGPLGDDLEGASRPGHFAGVLTVVCKLLHIVRPDRAFF
GEKDYQQLVLIRQMVTDLNIDTKIVGVPTVREADGLALSSRNRYLDEVEREQAGALSAALLAGMYAASNGAAATLDAARA
VLDEVPAIEVDYLQVRDPMLGPVPHEGAARLLVAARLGQTRLLDNIAVDIGASDGIDGHPRVGSPDHQLPWRN
>Mature_312_residues
TARRPTRFAKGELNVYRAPRDVTDVTRALRSTGRRVVLVPTMGALHEGHLTLIRAAKRVQGAVVVVSIFVNPLQFGAGED
LDAYPRTLDDDLAALRAEGVEIAFTPTVGDMYPDGTRTSVHPGPLGDDLEGASRPGHFAGVLTVVCKLLHIVRPDRAFFG
EKDYQQLVLIRQMVTDLNIDTKIVGVPTVREADGLALSSRNRYLDEVEREQAGALSAALLAGMYAASNGAAATLDAARAV
LDEVPAIEVDYLQVRDPMLGPVPHEGAARLLVAARLGQTRLLDNIAVDIGASDGIDGHPRVGSPDHQLPWRN

Specific function: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate [H]

COG id: COG0414

COG function: function code H; Panthothenate synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pantothenate synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786325, Length=279, Percent_Identity=47.6702508960573, Blast_Score=223, Evalue=1e-59,
Organism=Saccharomyces cerevisiae, GI6322046, Length=214, Percent_Identity=43.9252336448598, Blast_Score=166, Evalue=4e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003721
- InterPro:   IPR014729 [H]

Pfam domain/function: PF02569 Pantoate_ligase [H]

EC number: =6.3.2.1 [H]

Molecular weight: Translated: 33669; Mature: 33538

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTARRPTRFAKGELNVYRAPRDVTDVTRALRSTGRRVVLVPTMGALHEGHLTLIRAAKRV
CCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHH
QGAVVVVSIFVNPLQFGAGEDLDAYPRTLDDDLAALRAEGVEIAFTPTVGDMYPDGTRTS
CCCEEEEEEHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCEEEEEECCCCCCCCCCCCCC
VHPGPLGDDLEGASRPGHFAGVLTVVCKLLHIVRPDRAFFGEKDYQQLVLIRQMVTDLNI
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHCCC
DTKIVGVPTVREADGLALSSRNRYLDEVEREQAGALSAALLAGMYAASNGAAATLDAARA
CEEEEECCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
VLDEVPAIEVDYLQVRDPMLGPVPHEGAARLLVAARLGQTRLLDNIAVDIGASDGIDGHP
HHHHCCCCEEEHEEECCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHEEECCCCCCCCCCC
RVGSPDHQLPWRN
CCCCCCCCCCCCC
>Mature Secondary Structure 
TARRPTRFAKGELNVYRAPRDVTDVTRALRSTGRRVVLVPTMGALHEGHLTLIRAAKRV
CCCCCCCCCCCCCEEEECCCCHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHH
QGAVVVVSIFVNPLQFGAGEDLDAYPRTLDDDLAALRAEGVEIAFTPTVGDMYPDGTRTS
CCCEEEEEEHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCEEEEEECCCCCCCCCCCCCC
VHPGPLGDDLEGASRPGHFAGVLTVVCKLLHIVRPDRAFFGEKDYQQLVLIRQMVTDLNI
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHCCC
DTKIVGVPTVREADGLALSSRNRYLDEVEREQAGALSAALLAGMYAASNGAAATLDAARA
CEEEEECCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
VLDEVPAIEVDYLQVRDPMLGPVPHEGAARLLVAARLGQTRLLDNIAVDIGASDGIDGHP
HHHHCCCCEEEHEEECCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHEEECCCCCCCCCCC
RVGSPDHQLPWRN
CCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA