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The map label for this gene is panD

Identifier: 108801724

GI number: 108801724

Start: 5038797

End: 5039204

Strand: Reverse

Name: panD

Synonym: Mmcs_4761

Alternate gene names: 108801724

Gene position: 5039204-5038797 (Counterclockwise)

Preceding gene: 108801725

Following gene: 108801723

Centisome position: 88.32

GC content: 65.93

Gene sequence:

>408_bases
ATGCTTCGCACGATGCTGAAGTCGAAGATCCACCGAGCCACCGTCACGCAGTCCGATCTGCACTACGTCGGCTCGGTCAC
CATCGACGCCGATCTGATGGACGCCGCCGACCTCATCGAGGGTGAGCAGGTCACCATCGTCGACATCGACAACGGCAACC
GCCTGGTGACCTACGCGATCACCGGCGCCCGCGGCAGCGGGGTGATCGGGATCAACGGCGCCGCAGCACATCTCGTGCAT
CCCGGCGATCTGGTCATCCTGATCGCCTACGGCACCATGGAAGACGCCGAGGCGCGCGCATATCAGCCGCGGGTGGTCTT
CGTCGACGCCGACAACCGGCAGGTCCATCTCGGCGCCGACCCGGCGATGGTGCCGGACACCGCCGTCGACCTGATGTCTC
CGCGTTGA

Upstream 100 bases:

>100_bases
GGCTGCTCGACAACATCGCCGTCGACATCGGCGCATCGGACGGTATCGACGGCCACCCCCGGGTCGGTTCGCCCGACCAC
CAACTGCCCTGGAGGAACTG

Downstream 100 bases:

>100_bases
GCCGGGGGCACCTCCCGCTTGCGGGGGCGAACGAAGTGACCCGAGAGATGACGAGGTAGCGCAGTGCTGCTCGCCATCGA
CGTCCGCAACACCCACACCA

Product: aspartate alpha-decarboxylase

Products: NA

Alternate protein names: Aspartate alpha-decarboxylase

Number of amino acids: Translated: 135; Mature: 135

Protein sequence:

>135_residues
MLRTMLKSKIHRATVTQSDLHYVGSVTIDADLMDAADLIEGEQVTIVDIDNGNRLVTYAITGARGSGVIGINGAAAHLVH
PGDLVILIAYGTMEDAEARAYQPRVVFVDADNRQVHLGADPAMVPDTAVDLMSPR

Sequences:

>Translated_135_residues
MLRTMLKSKIHRATVTQSDLHYVGSVTIDADLMDAADLIEGEQVTIVDIDNGNRLVTYAITGARGSGVIGINGAAAHLVH
PGDLVILIAYGTMEDAEARAYQPRVVFVDADNRQVHLGADPAMVPDTAVDLMSPR
>Mature_135_residues
MLRTMLKSKIHRATVTQSDLHYVGSVTIDADLMDAADLIEGEQVTIVDIDNGNRLVTYAITGARGSGVIGINGAAAHLVH
PGDLVILIAYGTMEDAEARAYQPRVVFVDADNRQVHLGADPAMVPDTAVDLMSPR

Specific function: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine

COG id: COG0853

COG function: function code H; Aspartate 1-decarboxylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the panD family

Homologues:

Organism=Escherichia coli, GI1786323, Length=112, Percent_Identity=50, Blast_Score=125, Evalue=7e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PAND_MYCSJ (A3Q6Y4)

Other databases:

- EMBL:   CP000580
- RefSeq:   YP_001073402.1
- ProteinModelPortal:   A3Q6Y4
- SMR:   A3Q6Y4
- STRING:   A3Q6Y4
- EnsemblBacteria:   EBMYCT00000051144
- GeneID:   4880845
- GenomeReviews:   CP000580_GR
- KEGG:   mjl:Mjls_5147
- eggNOG:   COG0853
- GeneTree:   EBGT00050000017253
- HOGENOM:   HBG302821
- OMA:   LYSKIHR
- PhylomeDB:   A3Q6Y4
- ProtClustDB:   PRK05449
- BioCyc:   MSP164757:MJLS_5147-MONOMER
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00446
- InterPro:   IPR009010
- InterPro:   IPR003190
- Gene3D:   G3DSA:2.40.40.20
- PANTHER:   PTHR21012
- PIRSF:   PIRSF006246
- ProDom:   PD009294
- TIGRFAMs:   TIGR00223

Pfam domain/function: PF02261 Asp_decarbox; SSF50692 Asp_decarb_fold

EC number: =4.1.1.11

Molecular weight: Translated: 14424; Mature: 14424

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: NA

Important sites: ACT_SITE 25-25 ACT_SITE 58-58 BINDING 57-57

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRTMLKSKIHRATVTQSDLHYVGSVTIDADLMDAADLIEGEQVTIVDIDNGNRLVTYAI
CCHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCHHHHCCCCEEEEEEECCCCEEEEEEE
TGARGSGVIGINGAAAHLVHPGDLVILIAYGTMEDAEARAYQPRVVFVDADNRQVHLGAD
ECCCCCCEEEECCCEEEEECCCCEEEEEEECCCCCCCCCCCCCEEEEEECCCCEEEECCC
PAMVPDTAVDLMSPR
CCCCCCCCEECCCCC
>Mature Secondary Structure
MLRTMLKSKIHRATVTQSDLHYVGSVTIDADLMDAADLIEGEQVTIVDIDNGNRLVTYAI
CCHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCHHHHCCCCEEEEEEECCCCEEEEEEE
TGARGSGVIGINGAAAHLVHPGDLVILIAYGTMEDAEARAYQPRVVFVDADNRQVHLGAD
ECCCCCCEEEECCCEEEEECCCCEEEEEEECCCCCCCCCCCCCEEEEEECCCCEEEECCC
PAMVPDTAVDLMSPR
CCCCCCCCEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA