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The map label for this gene is ilvE [H]

Identifier: 108801498

GI number: 108801498

Start: 4807833

End: 4808711

Strand: Reverse

Name: ilvE [H]

Synonym: Mmcs_4535

Alternate gene names: 108801498

Gene position: 4808711-4807833 (Counterclockwise)

Preceding gene: 108801501

Following gene: 108801488

Centisome position: 84.28

GC content: 70.99

Gene sequence:

>879_bases
ATGGCGAGCGGACCCGGTGTGGTCGTCACCCTCGACGGTGCCTTTCACGACCCGCAGACACCCCTGTTGCATGCCGACGA
CCTGGCCGCCGTCCGTGGCGACGGCATCTTCGAGACACTGCTGGTCCGCGACGGTCGTCCCTGCCTCCTGGAGGCGCACC
TCGGGAGGCTCACCCACTCGGCACGGCTGATGGAGTTGCCCGCCCCGGATCCGGCCCGGTGGCGTTCGGCGGTCACCGCC
GCGGTGCATCGCTGGACGGCGGACGGTGGCGGCGAAGGGGTGCTGCGCCTGGTATACAGCCGTGGCCGCGAAAGCGGAGG
AGCGCCAACCGCATTCGTCACGATCGGCGCCCTGCCGACGCGGGTGGCGGCCGCCCGCCGGGACGGGGTGGCGGCGTTGA
CGTTGGCGCGTGGGCTGCCGACTGAGGCCGCCGACCTGCCGTGGTTGCTCGCGGGGGCCAAGACACTGTCGTACGCGGTG
AACATGGCGGCACTGCGGCATGCCGAGAAGCACGGCGCAGGCGACGTCATCTTCGTCAGCTCCGACGGCCACATCCTCGA
GGGGCCGCGGTCGACGGTCGTGATCGCCACCGAGATGGAGGGCGGCGGGTTGGGGCTGCTCACCCCGCCGCCGTGGTATC
CGATCCTGCGCGGCACCACCCAGCAGGCGTTGTTCGAGGTCGCGCGCAACAAGGGTTACGACTGCGACTACCGGGCGCTG
CGCCCTGCGGATCTGGTTGCGGCACAAGGTGTCTGGCTGATCTCCAGTATCACCCTTGCGGCCCGTGTGCACACGCTGAA
CGGGGTGCCGCTGCGGCCGACGCCCCTGGTGGCCGAGGTGTCTGCGCTGGTCGACGCGGCCATCGTCAGCGATCGCTGA

Upstream 100 bases:

>100_bases
CCGAGCGGGTCGCCGTAGTGCCACACCGCCCCGACGTCCGGTCCTTCGGGGACGGGAACTGCTGACATGGCTCAACTCTA
CGGGTCTACGCTGATGGCCC

Downstream 100 bases:

>100_bases
CGGCGAATCGAAAATCCCTTGTCGGTGTCCGCGAGCGCGGGTACGGTCGCTCGTACACAGGGAAGGAGGTGGTCCGACAA
ATTGAGTGACTTATGGACAT

Product: 4-amino-4-deoxychorismate lyase

Products: NA

Alternate protein names: BCAT; Transaminase B [H]

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:

>292_residues
MASGPGVVVTLDGAFHDPQTPLLHADDLAAVRGDGIFETLLVRDGRPCLLEAHLGRLTHSARLMELPAPDPARWRSAVTA
AVHRWTADGGGEGVLRLVYSRGRESGGAPTAFVTIGALPTRVAAARRDGVAALTLARGLPTEAADLPWLLAGAKTLSYAV
NMAALRHAEKHGAGDVIFVSSDGHILEGPRSTVVIATEMEGGGLGLLTPPPWYPILRGTTQQALFEVARNKGYDCDYRAL
RPADLVAAQGVWLISSITLAARVHTLNGVPLRPTPLVAEVSALVDAAIVSDR

Sequences:

>Translated_292_residues
MASGPGVVVTLDGAFHDPQTPLLHADDLAAVRGDGIFETLLVRDGRPCLLEAHLGRLTHSARLMELPAPDPARWRSAVTA
AVHRWTADGGGEGVLRLVYSRGRESGGAPTAFVTIGALPTRVAAARRDGVAALTLARGLPTEAADLPWLLAGAKTLSYAV
NMAALRHAEKHGAGDVIFVSSDGHILEGPRSTVVIATEMEGGGLGLLTPPPWYPILRGTTQQALFEVARNKGYDCDYRAL
RPADLVAAQGVWLISSITLAARVHTLNGVPLRPTPLVAEVSALVDAAIVSDR
>Mature_291_residues
ASGPGVVVTLDGAFHDPQTPLLHADDLAAVRGDGIFETLLVRDGRPCLLEAHLGRLTHSARLMELPAPDPARWRSAVTAA
VHRWTADGGGEGVLRLVYSRGRESGGAPTAFVTIGALPTRVAAARRDGVAALTLARGLPTEAADLPWLLAGAKTLSYAVN
MAALRHAEKHGAGDVIFVSSDGHILEGPRSTVVIATEMEGGGLGLLTPPPWYPILRGTTQQALFEVARNKGYDCDYRALR
PADLVAAQGVWLISSITLAARVHTLNGVPLRPTPLVAEVSALVDAAIVSDR

Specific function: Acts on leucine, isoleucine and valine [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001544
- InterPro:   IPR018300
- InterPro:   IPR005785 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =2.6.1.42 [H]

Molecular weight: Translated: 30678; Mature: 30547

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASGPGVVVTLDGAFHDPQTPLLHADDLAAVRGDGIFETLLVRDGRPCLLEAHLGRLTHS
CCCCCEEEEEECCCCCCCCCCEEECCCHHHHCCCCCEEEEEECCCCCEEEEHHHHHHHCC
ARLMELPAPDPARWRSAVTAAVHRWTADGGGEGVLRLVYSRGRESGGAPTAFVTIGALPT
CEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEECCCHH
RVAAARRDGVAALTLARGLPTEAADLPWLLAGAKTLSYAVNMAALRHAEKHGAGDVIFVS
HHHHHHCCCEEEEEECCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEEC
SDGHILEGPRSTVVIATEMEGGGLGLLTPPPWYPILRGTTQQALFEVARNKGYDCDYRAL
CCCCEEECCCCEEEEEEEECCCCEECCCCCCCCHHHCCCHHHHHHHHHHCCCCCCCCCCC
RPADLVAAQGVWLISSITLAARVHTLNGVPLRPTPLVAEVSALVDAAIVSDR
CCHHHHHHCCCHHHHHHHHHHEEEECCCCCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ASGPGVVVTLDGAFHDPQTPLLHADDLAAVRGDGIFETLLVRDGRPCLLEAHLGRLTHS
CCCCEEEEEECCCCCCCCCCEEECCCHHHHCCCCCEEEEEECCCCCEEEEHHHHHHHCC
ARLMELPAPDPARWRSAVTAAVHRWTADGGGEGVLRLVYSRGRESGGAPTAFVTIGALPT
CEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEECCCHH
RVAAARRDGVAALTLARGLPTEAADLPWLLAGAKTLSYAVNMAALRHAEKHGAGDVIFVS
HHHHHHCCCEEEEEECCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEEC
SDGHILEGPRSTVVIATEMEGGGLGLLTPPPWYPILRGTTQQALFEVARNKGYDCDYRAL
CCCCEEECCCCEEEEEEEECCCCEECCCCCCCCHHHCCCHHHHHHHHHHCCCCCCCCCCC
RPADLVAAQGVWLISSITLAARVHTLNGVPLRPTPLVAEVSALVDAAIVSDR
CCHHHHHHCCCHHHHHHHHHHEEEECCCCCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]