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The map label for this gene is fprB [H]

Identifier: 108801425

GI number: 108801425

Start: 4743522

End: 4745207

Strand: Reverse

Name: fprB [H]

Synonym: Mmcs_4462

Alternate gene names: 108801425

Gene position: 4745207-4743522 (Counterclockwise)

Preceding gene: 108801426

Following gene: 108801421

Centisome position: 83.17

GC content: 72.95

Gene sequence:

>1686_bases
GTGCCCCATGTGATCACCCAGTCGTGCTGCAGTGACGGGTCGTGTGTCTTCGCCTGCCCGGTGAACTGCATCCACCCCAC
ACCCGACGAGCCGGGCTTCGCGACCGCCGAGATGCTCTACATCGACCCGGCGGCCTGCGTCGACTGCGGAGCCTGCGTCA
GCGCCTGTCCGGTCGGCGCGATCGCCCCTGAGGCCACGTTGACCGACTCGCAGCTGCCGTTCGTCGAACTCAACGCGGCG
TTCTATCCACCGCGCCCGCCCGACGAGAAGGTGCCGCCCACCTCCAAGCTGGCGCCGGTGCCCGACGCCCCCGTCGTCCG
CTCACGTCCCGACGGCCCGCTGAGGGTCGCCATCGTGGGATCCGGCCCGGCCGCCATGTACGCCGCCGACGAACTGCTCA
CCCAGCGCGGGGTGCGGGTCACGATGTTCGAGCGGCTGCCCACGCCCTACGGGCTGGTCCGCGCGGGCGTCGCCCCCGAC
CACCAGAGCACCAAGCGGGTGACGCGGTTGTTCGACCGGGTGGCGGCGCGGCGTGAGCTGAGGCTCTACCTCAACGTCGA
GGTCGGCACCCACCTGACCCACGAAGACCTGCTGGCCCACCACCACGCCGTGCTGTACGCCGTCGGCGCCCCCAACGACC
GCCGCCTCGACGTCGACGGGATGGGCCTGCCCGGCACGGCGACAGCCACCGAGGTCGTCGCCTGGTACAACGGCCACCCC
GACTACGCGGCCCTGCCGGTCGCACTCGACCACCGCCGAGCGGTCGTGATCGGAAACGGCAACGTGGCACTCGACGTCGC
CCGCATCCTCACCACCGACCCGGACCGGCTGGCCGCCACCGACATCGCCGACCACGCGCTGGCCGCGCTGCGCGCCTCGC
GCATCGACGAGGTGGTGGTCGCGGCCCGGCGCGGGCCCGCGCAGTCGGCGTTCACGCTGCCCGAGCTGATCGGTCTCACC
GCCGCCTGCGACGTCGTGCTCGACGCGGCCGACCACGAACTGGTCCGGCGCGACCTCTGCGACGAAACCGATCCGCTCAC
CCGCAACAAGCTCGAGATCCTCGCGAAGCTGCCCGACGCCTCGGCGCCGGCCACCCGCCCGCGGATCCGGCTGGCCTACC
GGCTGACACCGCGACGCGTCACCGGTGCGACCCGCGCCGACGGTGTCGAGTTCACCGTCACCGGTACCGACGAGGTGCGC
CGCCTCGACGCCGGGCTCGTGCTGTCCTCCATCGGCTACCGCGGCAGGCCGGTCGCGGGGTTGCCGTTCGACGAGGCCGA
CGGCGTCGTCCCCAACGAGAGTGGCCGTGTCGTCGACCCGGCGTCCGGCCGATCCGTCCCGGGAAGTTACGTCGCGGGCT
GGATCAAGCGCGGACCGACCGGCTTCATCGGTACCAACAAGTCCTGCGCCGCGCAGACGGTGCACACCCTCGTGGCCGAT
TACAACGCCGGCGCACTCGCGGTGCCGTCGGCCGGCTACGGCGATCTGGACCGGTTCGTGCGAGAGCGTCGGCCCGACGT
GGTCGACAGCCAGGGCTGGCGCGCCATCGACGCGGCGGAGATCGCCCGCGGGGGTGACCGACGCCCGCGGGTGAAGTTCA
CGTCGGTCGCCGACATGCTGCAGGCGGCGGCCGCCGCGCCGGAGCCGCCGCTCGCGCGGCGTCTGCTCGCCGGTCTGCTG
CGGTAG

Upstream 100 bases:

>100_bases
TGATGTGGCGCATCTGCCGGATCGACGGGCGGCCCAGCCGCTACCGCAGCGAACCGCACCGCCAACACGTCGCCACCGCG
GCCTAGGGGGACGCACGACC

Downstream 100 bases:

>100_bases
CGGCGGCCACGCCGCACGTCGCTACTGATTGCTCATCGCGGCCTGCATCTCCTCCTGGCTGACCTCGCGCACCGGCTGTC
CCATCGACCACAGGTGGCCG

Product: 4Fe-4S ferredoxin, iron-sulfur binding protein

Products: NA

Alternate protein names: FNR [H]

Number of amino acids: Translated: 561; Mature: 560

Protein sequence:

>561_residues
MPHVITQSCCSDGSCVFACPVNCIHPTPDEPGFATAEMLYIDPAACVDCGACVSACPVGAIAPEATLTDSQLPFVELNAA
FYPPRPPDEKVPPTSKLAPVPDAPVVRSRPDGPLRVAIVGSGPAAMYAADELLTQRGVRVTMFERLPTPYGLVRAGVAPD
HQSTKRVTRLFDRVAARRELRLYLNVEVGTHLTHEDLLAHHHAVLYAVGAPNDRRLDVDGMGLPGTATATEVVAWYNGHP
DYAALPVALDHRRAVVIGNGNVALDVARILTTDPDRLAATDIADHALAALRASRIDEVVVAARRGPAQSAFTLPELIGLT
AACDVVLDAADHELVRRDLCDETDPLTRNKLEILAKLPDASAPATRPRIRLAYRLTPRRVTGATRADGVEFTVTGTDEVR
RLDAGLVLSSIGYRGRPVAGLPFDEADGVVPNESGRVVDPASGRSVPGSYVAGWIKRGPTGFIGTNKSCAAQTVHTLVAD
YNAGALAVPSAGYGDLDRFVRERRPDVVDSQGWRAIDAAEIARGGDRRPRVKFTSVADMLQAAAAAPEPPLARRLLAGLL
R

Sequences:

>Translated_561_residues
MPHVITQSCCSDGSCVFACPVNCIHPTPDEPGFATAEMLYIDPAACVDCGACVSACPVGAIAPEATLTDSQLPFVELNAA
FYPPRPPDEKVPPTSKLAPVPDAPVVRSRPDGPLRVAIVGSGPAAMYAADELLTQRGVRVTMFERLPTPYGLVRAGVAPD
HQSTKRVTRLFDRVAARRELRLYLNVEVGTHLTHEDLLAHHHAVLYAVGAPNDRRLDVDGMGLPGTATATEVVAWYNGHP
DYAALPVALDHRRAVVIGNGNVALDVARILTTDPDRLAATDIADHALAALRASRIDEVVVAARRGPAQSAFTLPELIGLT
AACDVVLDAADHELVRRDLCDETDPLTRNKLEILAKLPDASAPATRPRIRLAYRLTPRRVTGATRADGVEFTVTGTDEVR
RLDAGLVLSSIGYRGRPVAGLPFDEADGVVPNESGRVVDPASGRSVPGSYVAGWIKRGPTGFIGTNKSCAAQTVHTLVAD
YNAGALAVPSAGYGDLDRFVRERRPDVVDSQGWRAIDAAEIARGGDRRPRVKFTSVADMLQAAAAAPEPPLARRLLAGLL
R
>Mature_560_residues
PHVITQSCCSDGSCVFACPVNCIHPTPDEPGFATAEMLYIDPAACVDCGACVSACPVGAIAPEATLTDSQLPFVELNAAF
YPPRPPDEKVPPTSKLAPVPDAPVVRSRPDGPLRVAIVGSGPAAMYAADELLTQRGVRVTMFERLPTPYGLVRAGVAPDH
QSTKRVTRLFDRVAARRELRLYLNVEVGTHLTHEDLLAHHHAVLYAVGAPNDRRLDVDGMGLPGTATATEVVAWYNGHPD
YAALPVALDHRRAVVIGNGNVALDVARILTTDPDRLAATDIADHALAALRASRIDEVVVAARRGPAQSAFTLPELIGLTA
ACDVVLDAADHELVRRDLCDETDPLTRNKLEILAKLPDASAPATRPRIRLAYRLTPRRVTGATRADGVEFTVTGTDEVRR
LDAGLVLSSIGYRGRPVAGLPFDEADGVVPNESGRVVDPASGRSVPGSYVAGWIKRGPTGFIGTNKSCAAQTVHTLVADY
NAGALAVPSAGYGDLDRFVRERRPDVVDSQGWRAIDAAEIARGGDRRPRVKFTSVADMLQAAAAAPEPPLARRLLAGLLR

Specific function: Unknown

COG id: COG0493

COG function: function code ER; NADPH-dependent glutamate synthase beta chain and related oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Homo sapiens, GI111118981, Length=454, Percent_Identity=38.7665198237885, Blast_Score=261, Evalue=2e-69,
Organism=Homo sapiens, GI111118983, Length=461, Percent_Identity=39.0455531453362, Blast_Score=256, Evalue=4e-68,
Organism=Escherichia coli, GI87082180, Length=238, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1789606, Length=161, Percent_Identity=31.6770186335404, Blast_Score=67, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17543860, Length=446, Percent_Identity=31.390134529148, Blast_Score=184, Evalue=9e-47,
Organism=Saccharomyces cerevisiae, GI6320584, Length=487, Percent_Identity=27.7207392197125, Blast_Score=160, Evalue=6e-40,
Organism=Drosophila melanogaster, GI17137178, Length=446, Percent_Identity=35.8744394618834, Blast_Score=226, Evalue=3e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR013027
- InterPro:   IPR021163
- InterPro:   IPR016040 [H]

Pfam domain/function: PF07992 Pyr_redox_2 [H]

EC number: =1.18.1.2 [H]

Molecular weight: Translated: 59688; Mature: 59557

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHVITQSCCSDGSCVFACPVNCIHPTPDEPGFATAEMLYIDPAACVDCGACVSACPVGA
CCCCCCHHHCCCCCEEEECCCCCCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHCCCCC
IAPEATLTDSQLPFVELNAAFYPPRPPDEKVPPTSKLAPVPDAPVVRSRPDGPLRVAIVG
CCCCCCCCCCCCCEEEECCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEE
SGPAAMYAADELLTQRGVRVTMFERLPTPYGLVRAGVAPDHQSTKRVTRLFDRVAARREL
CCCHHHHHHHHHHHHCCCEEEEHHHCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHCEEE
RLYLNVEVGTHLTHEDLLAHHHAVLYAVGAPNDRRLDVDGMGLPGTATATEVVAWYNGHP
EEEEEEEECCCCCHHHHHHHCCEEEEEECCCCCCEEECCCCCCCCCCCHHHEEEEECCCC
DYAALPVALDHRRAVVIGNGNVALDVARILTTDPDRLAATDIADHALAALRASRIDEVVV
CCEEEEEEECCCEEEEEECCCEEEEEHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AARRGPAQSAFTLPELIGLTAACDVVLDAADHELVRRDLCDETDPLTRNKLEILAKLPDA
HHCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCC
SAPATRPRIRLAYRLTPRRVTGATRADGVEFTVTGTDEVRRLDAGLVLSSIGYRGRPVAG
CCCCCCCEEEEEEEECCHHCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHCCCCCCCCCC
LPFDEADGVVPNESGRVVDPASGRSVPGSYVAGWIKRGPTGFIGTNKSCAAQTVHTLVAD
CCCCCCCCCCCCCCCCEECCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHC
YNAGALAVPSAGYGDLDRFVRERRPDVVDSQGWRAIDAAEIARGGDRRPRVKFTSVADML
CCCCEEECCCCCCHHHHHHHHHHCCCCCCCCCCCEECHHHHHCCCCCCCCEEHHHHHHHH
QAAAAAPEPPLARRLLAGLLR
HHHHCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
PHVITQSCCSDGSCVFACPVNCIHPTPDEPGFATAEMLYIDPAACVDCGACVSACPVGA
CCCCCHHHCCCCCEEEECCCCCCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHCCCCC
IAPEATLTDSQLPFVELNAAFYPPRPPDEKVPPTSKLAPVPDAPVVRSRPDGPLRVAIVG
CCCCCCCCCCCCCEEEECCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEE
SGPAAMYAADELLTQRGVRVTMFERLPTPYGLVRAGVAPDHQSTKRVTRLFDRVAARREL
CCCHHHHHHHHHHHHCCCEEEEHHHCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHCEEE
RLYLNVEVGTHLTHEDLLAHHHAVLYAVGAPNDRRLDVDGMGLPGTATATEVVAWYNGHP
EEEEEEEECCCCCHHHHHHHCCEEEEEECCCCCCEEECCCCCCCCCCCHHHEEEEECCCC
DYAALPVALDHRRAVVIGNGNVALDVARILTTDPDRLAATDIADHALAALRASRIDEVVV
CCEEEEEEECCCEEEEEECCCEEEEEHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AARRGPAQSAFTLPELIGLTAACDVVLDAADHELVRRDLCDETDPLTRNKLEILAKLPDA
HHCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCC
SAPATRPRIRLAYRLTPRRVTGATRADGVEFTVTGTDEVRRLDAGLVLSSIGYRGRPVAG
CCCCCCCEEEEEEEECCHHCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHCCCCCCCCCC
LPFDEADGVVPNESGRVVDPASGRSVPGSYVAGWIKRGPTGFIGTNKSCAAQTVHTLVAD
CCCCCCCCCCCCCCCCEECCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHC
YNAGALAVPSAGYGDLDRFVRERRPDVVDSQGWRAIDAAEIARGGDRRPRVKFTSVADML
CCCCEEECCCCCCHHHHHHHHHHCCCCCCCCCCCEECHHHHHCCCCCCCCEEHHHHHHHH
QAAAAAPEPPLARRLLAGLLR
HHHHCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]