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The map label for this gene is yabD [H]

Identifier: 108801229

GI number: 108801229

Start: 4531420

End: 4532217

Strand: Reverse

Name: yabD [H]

Synonym: Mmcs_4265

Alternate gene names: 108801229

Gene position: 4532217-4531420 (Counterclockwise)

Preceding gene: 108801237

Following gene: 108801228

Centisome position: 79.44

GC content: 72.18

Gene sequence:

>798_bases
TTGACGCCGCTGATCGATGCGCACACCCACCTCGACGCCTGCGGCGCGCGCGACGGTGACGACGTGCGGGCGGTGCTGGA
CCGGGCGGGCGCGGTCGGCGTGGGCGCCGTCGTGACGATCGCCGACGATCTGGCCTCGGCGCACTGGGCCACCCGGGCCG
CCGACTGGGATGACCGGGTCTACGCGGCCGTGGCCCTGCACCCCACCCGCGCCGATGCGCTGACCGACGAGGCGAAGGTC
GAGATCGAACGGCTCGTCGCCCACCCGCGGGTGGTGGCGGTCGGGGAGACCGGGCTGGATCTGTACTGGCCCGGCAAGCT
CGACGGCTGCGCCGAGCCGGAGGTGCAGCGGGAGGCGTTCGCCTGGCACATCGACCTCGCCAAGTGCACCGGCAAGCCGC
TGATGATCCACAACCGCGATGCCGACGCGGCCGTCCTCGACGTACTCGCCGCCGAGGGCGCGCCGGAGACGGTGATCTTC
CACTGCTTCTCCTCGGATGCGCAGATGGCCCGCACCTGTGTGGACGCCGGCTGGCTGCTGAGCCTTTCGGGCACGGTGAG
CTTCCGGAACGCGCATGCCCTGCGGGAGGCGGCGCAGCTGATCCCCGGCGAGCAGCTCCTCGTCGAAACGGATGCACCAT
TTCTCACCCCGCACCCGTACCGCGGCGCCCCCAACGAGCCGTACTGCCTGCCGTACACCGTCCGCGCCCTGGCCGAGGTC
CGCGGCGAGCCGGCCGAGGAGCTGGCTCAGCAAACCGCCGACAACGCGATCCGCGCGTACGCACTCCGTACGGGTTGA

Upstream 100 bases:

>100_bases
GATCGCGGTGGTGATGTAGAACGGCTGACTCATTTGGGTTCACCTTATGGTGTGGGACGTGAGTCGATCGAACCGTCCGG
CACCGCCGGCTCCCGAGCCG

Downstream 100 bases:

>100_bases
TCTCAGTAAAGGAGTTCGTTACCGTCTTGTGATCGTAAGCGGACTTAGCTCCGCTTTTTTTGAAACGTTTGTACCAATAA
CAGGGATTCGACCACTTGAC

Product: TatD-related deoxyribonuclease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 265; Mature: 264

Protein sequence:

>265_residues
MTPLIDAHTHLDACGARDGDDVRAVLDRAGAVGVGAVVTIADDLASAHWATRAADWDDRVYAAVALHPTRADALTDEAKV
EIERLVAHPRVVAVGETGLDLYWPGKLDGCAEPEVQREAFAWHIDLAKCTGKPLMIHNRDADAAVLDVLAAEGAPETVIF
HCFSSDAQMARTCVDAGWLLSLSGTVSFRNAHALREAAQLIPGEQLLVETDAPFLTPHPYRGAPNEPYCLPYTVRALAEV
RGEPAEELAQQTADNAIRAYALRTG

Sequences:

>Translated_265_residues
MTPLIDAHTHLDACGARDGDDVRAVLDRAGAVGVGAVVTIADDLASAHWATRAADWDDRVYAAVALHPTRADALTDEAKV
EIERLVAHPRVVAVGETGLDLYWPGKLDGCAEPEVQREAFAWHIDLAKCTGKPLMIHNRDADAAVLDVLAAEGAPETVIF
HCFSSDAQMARTCVDAGWLLSLSGTVSFRNAHALREAAQLIPGEQLLVETDAPFLTPHPYRGAPNEPYCLPYTVRALAEV
RGEPAEELAQQTADNAIRAYALRTG
>Mature_264_residues
TPLIDAHTHLDACGARDGDDVRAVLDRAGAVGVGAVVTIADDLASAHWATRAADWDDRVYAAVALHPTRADALTDEAKVE
IERLVAHPRVVAVGETGLDLYWPGKLDGCAEPEVQREAFAWHIDLAKCTGKPLMIHNRDADAAVLDVLAAEGAPETVIFH
CFSSDAQMARTCVDAGWLLSLSGTVSFRNAHALREAAQLIPGEQLLVETDAPFLTPHPYRGAPNEPYCLPYTVRALAEVR
GEPAEELAQQTADNAIRAYALRTG

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI110349730, Length=267, Percent_Identity=29.2134831460674, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI110349734, Length=267, Percent_Identity=28.4644194756554, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI226061853, Length=273, Percent_Identity=28.2051282051282, Blast_Score=88, Evalue=7e-18,
Organism=Homo sapiens, GI225903424, Length=216, Percent_Identity=30.0925925925926, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI226061614, Length=260, Percent_Identity=27.3076923076923, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI14042943, Length=271, Percent_Identity=24.7232472324723, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI226061595, Length=230, Percent_Identity=28.695652173913, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1787342, Length=266, Percent_Identity=36.8421052631579, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI87082439, Length=265, Percent_Identity=30.9433962264151, Blast_Score=109, Evalue=1e-25,
Organism=Escherichia coli, GI48994985, Length=257, Percent_Identity=32.6848249027237, Blast_Score=105, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI71980746, Length=267, Percent_Identity=28.4644194756554, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17559024, Length=272, Percent_Identity=28.6764705882353, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17543026, Length=191, Percent_Identity=29.8429319371728, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17565396, Length=190, Percent_Identity=31.0526315789474, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24648690, Length=273, Percent_Identity=28.2051282051282, Blast_Score=88, Evalue=6e-18,
Organism=Drosophila melanogaster, GI221330018, Length=277, Percent_Identity=24.9097472924188, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24586117, Length=277, Percent_Identity=24.9097472924188, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 28446; Mature: 28315

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: PS01137 TATD_1 ; PS01091 TATD_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPLIDAHTHLDACGARDGDDVRAVLDRAGAVGVGAVVTIADDLASAHWATRAADWDDRV
CCCCCCCCCCHHHCCCCCCHHHHHHHHHCCCCCCCHHEEEHHHHHHHHHHHCCCCCCCCE
YAAVALHPTRADALTDEAKVEIERLVAHPRVVAVGETGLDLYWPGKLDGCAEPEVQREAF
EEEEEECCCHHHHHCHHHHHHHHHHHCCCEEEEECCCCCEEEECCCCCCCCCCCHHHHHE
AWHIDLAKCTGKPLMIHNRDADAAVLDVLAAEGAPETVIFHCFSSDAQMARTCVDAGWLL
EEEEEHHHHCCCEEEEECCCCCHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHCCCEEE
SLSGTVSFRNAHALREAAQLIPGEQLLVETDAPFLTPHPYRGAPNEPYCLPYTVRALAEV
EECCEEEEHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCEECHHHHHHHHHH
RGEPAEELAQQTADNAIRAYALRTG
CCCCHHHHHHHHHCCCEEEEEEECC
>Mature Secondary Structure 
TPLIDAHTHLDACGARDGDDVRAVLDRAGAVGVGAVVTIADDLASAHWATRAADWDDRV
CCCCCCCCCHHHCCCCCCHHHHHHHHHCCCCCCCHHEEEHHHHHHHHHHHCCCCCCCCE
YAAVALHPTRADALTDEAKVEIERLVAHPRVVAVGETGLDLYWPGKLDGCAEPEVQREAF
EEEEEECCCHHHHHCHHHHHHHHHHHCCCEEEEECCCCCEEEECCCCCCCCCCCHHHHHE
AWHIDLAKCTGKPLMIHNRDADAAVLDVLAAEGAPETVIFHCFSSDAQMARTCVDAGWLL
EEEEEHHHHCCCEEEEECCCCCHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHCCCEEE
SLSGTVSFRNAHALREAAQLIPGEQLLVETDAPFLTPHPYRGAPNEPYCLPYTVRALAEV
EECCEEEEHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCEECHHHHHHHHHH
RGEPAEELAQQTADNAIRAYALRTG
CCCCHHHHHHHHHCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]