Click here to switch to the map view.

The map label for this gene is cmtR [H]

Identifier: 108801153

GI number: 108801153

Start: 4453567

End: 4453920

Strand: Reverse

Name: cmtR [H]

Synonym: Mmcs_4189

Alternate gene names: 108801153

Gene position: 4453920-4453567 (Counterclockwise)

Preceding gene: 108801159

Following gene: 108801152

Centisome position: 78.06

GC content: 69.49

Gene sequence:

>354_bases
ATGTACTGTCGGACGGTGCTGACGCTGACCCACACCGATGCCCTCGCGCGGTTCGGCCACGCGCTGTCGGACATCACCCG
CGCGCGAATCCTGCTGCGGCTGAGCCGGGCCTCCGGATACCCCTCCGACCTGGCCGAACAACTCGGGGTCAGCCGGCAGA
TACTGTCCAACCATCTGGCCTGTCTGCGCGGCTGCGGCCTGGTGGTGGCGGTACCGGAGGGCCGGCGCAGCCGCTACGAA
CTGGCCGACCCGCGGATCGGCGCGGCGCTCGACGATCTGATGGGACTGGTGCTGGCGGTCGACCCGAACTGCTGTTGCAC
CGGTGACGACGGCGACGGATGCAGGTGCTGCTGA

Upstream 100 bases:

>100_bases
CTTGTGCAGGGGACTTCATTGCGTCACGGCAACGTTATCGAATTGTTACCAAAGGCTGTCGCGCCCGGCCGACCGATCGT
GGACGACAGTACAGATTCTG

Downstream 100 bases:

>100_bases
TGGCCGCCGATCGAGCCCTGACCGCACACCGGCGCGAGATCCTTTCGCGACGCATCCGGTGGTTCGTCACGGCCACCATC
TCCTACAACATCGTCGAGGC

Product: ArsR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 117; Mature: 117

Protein sequence:

>117_residues
MYCRTVLTLTHTDALARFGHALSDITRARILLRLSRASGYPSDLAEQLGVSRQILSNHLACLRGCGLVVAVPEGRRSRYE
LADPRIGAALDDLMGLVLAVDPNCCCTGDDGDGCRCC

Sequences:

>Translated_117_residues
MYCRTVLTLTHTDALARFGHALSDITRARILLRLSRASGYPSDLAEQLGVSRQILSNHLACLRGCGLVVAVPEGRRSRYE
LADPRIGAALDDLMGLVLAVDPNCCCTGDDGDGCRCC
>Mature_117_residues
MYCRTVLTLTHTDALARFGHALSDITRARILLRLSRASGYPSDLAEQLGVSRQILSNHLACLRGCGLVVAVPEGRRSRYE
LADPRIGAALDDLMGLVLAVDPNCCCTGDDGDGCRCC

Specific function: Metal-responsive transcriptional repressor for the cmt operon. Binding of cadmium or lead causes the repressor to dissociate from the DNA [H]

COG id: COG0640

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 12579; Mature: 12579

Theoretical pI: Translated: 7.22; Mature: 7.22

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

7.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
9.4 %Cys+Met (Translated Protein)
7.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
9.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYCRTVLTLTHTDALARFGHALSDITRARILLRLSRASGYPSDLAEQLGVSRQILSNHLA
CCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCHHHHHHHHHHH
CLRGCGLVVAVPEGRRSRYELADPRIGAALDDLMGLVLAVDPNCCCTGDDGDGCRCC
HHHCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHEECCCCEECCCCCCCCCCC
>Mature Secondary Structure
MYCRTVLTLTHTDALARFGHALSDITRARILLRLSRASGYPSDLAEQLGVSRQILSNHLA
CCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCHHHHHHHHHHH
CLRGCGLVVAVPEGRRSRYELADPRIGAALDDLMGLVLAVDPNCCCTGDDGDGCRCC
HHHCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHEECCCCEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]