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The map label for this gene is dapE [H]

Identifier: 108800976

GI number: 108800976

Start: 4278056

End: 4279156

Strand: Reverse

Name: dapE [H]

Synonym: Mmcs_4012

Alternate gene names: 108800976

Gene position: 4279156-4278056 (Counterclockwise)

Preceding gene: 108800978

Following gene: 108800975

Centisome position: 75.0

GC content: 71.12

Gene sequence:

>1101_bases
ATGGCCCCATCATCGGCTCTTCGCGCAAGCGGCTCATCGCTGGATCTCCGTGGTGACCCGGTCGAGCTGACGGCCGCACT
CGTCGACATCCCCAGCGAGTCGCGCCACGAGCAGCGCATCGCCGACGAGATCGAGGCCGCACTGCGCGAACAGACAGACG
GTTTCGAGATCATCCGCAACGGCGACGCGGTGCTGGCCCGCACCAACCGGGGGCTCCCGTCACGCGTGCTGCTGGCCGGG
CACATCGACACCGTGCCCGCCGCCGACAACGTCCCCAGCCGCCGGGTCGGTGACGAGCTGCACGGCTGCGGCACCTCCGA
CATGAAGTCCGGGGACGCGGTGTTCCTGCACCTCGCCGCCACTGTCGCCGACCCCGCACACGACCTCACGCTGGTGATGT
ACGACTGCGAAGAGATCGAGGCGTCGGCCAACGGGCTCGGCCGCATCGAACGCGAACTGCCCGAGTGGCTGCAGGCCGAC
GTCGCGATCCTCGGCGAACCGTCCGGCGGTTTCATCGAGGCCGGCTGCCAGGGCACGCTGCGAGTCGTGGTGAGCGCCAC
CGGAACCCGGGCGCACTCCGCGCGATCCTGGTTGGGCGACAACGCCATTCACAAACTCGGCGCGGTCCTCGACCGGTTGG
CCGCCTACCAGGCCCGCAGCATCGACATCGACGGCTGCGTCTACCGCGAGGGACTCTCCGCGGTGCGCATCGACGGCGGC
ATCGCGGGCAACGTGATCCCCGACGCCGCCTCGGTCACCGTCAACTTCCGCTTCGCCCCCGACCGCACCGTCGACCAGGC
GCTGGCCCACGTCCACGAGGTCCTCGACGGACTCGACGTCACCGTCGAGCAGACCGACGCCGCCGCCGGAGCCCTGCCGG
GGCTGACCAGGCCGGCGGCCGCGGCGCTGGTCGAGGCCGCCGGCGGACAGGCGCGGGCCAAGTACGGGTGGACCGACGTG
GCGCGGTTCGCGGCGCTGGGGATCCCGGCCGTCAATTACGGTCCGGGGGATCCGAACCTCGCCCACCGCGCGGACGAACG
GGTCGACGTCGGCCAGATCACCGCGACCACCGAGGTGCTGCGCCGGTATTTAACCGCTTGA

Upstream 100 bases:

>100_bases
CGCCGGGTACCAGGTGTCGAGGACGGTTCCGTCGGCGGCGATGGTGGCCAGGCCGATTCCTGCAGCAGAAGTCACGGAGC
TAGAGATTACCGTTGACCTC

Downstream 100 bases:

>100_bases
CGCGCTGACTTACCCTCGAAGACATGTGGGGAGACGACGACATCTCCGGGTGATCCGGAAAACCTGCTCGTCCGTACTCG
TACCCTCCTCGAAAGTCCCC

Product: succinyl-diaminopimelate desuccinylase

Products: NA

Alternate protein names: SDAP desuccinylase [H]

Number of amino acids: Translated: 366; Mature: 365

Protein sequence:

>366_residues
MAPSSALRASGSSLDLRGDPVELTAALVDIPSESRHEQRIADEIEAALREQTDGFEIIRNGDAVLARTNRGLPSRVLLAG
HIDTVPAADNVPSRRVGDELHGCGTSDMKSGDAVFLHLAATVADPAHDLTLVMYDCEEIEASANGLGRIERELPEWLQAD
VAILGEPSGGFIEAGCQGTLRVVVSATGTRAHSARSWLGDNAIHKLGAVLDRLAAYQARSIDIDGCVYREGLSAVRIDGG
IAGNVIPDAASVTVNFRFAPDRTVDQALAHVHEVLDGLDVTVEQTDAAAGALPGLTRPAAAALVEAAGGQARAKYGWTDV
ARFAALGIPAVNYGPGDPNLAHRADERVDVGQITATTEVLRRYLTA

Sequences:

>Translated_366_residues
MAPSSALRASGSSLDLRGDPVELTAALVDIPSESRHEQRIADEIEAALREQTDGFEIIRNGDAVLARTNRGLPSRVLLAG
HIDTVPAADNVPSRRVGDELHGCGTSDMKSGDAVFLHLAATVADPAHDLTLVMYDCEEIEASANGLGRIERELPEWLQAD
VAILGEPSGGFIEAGCQGTLRVVVSATGTRAHSARSWLGDNAIHKLGAVLDRLAAYQARSIDIDGCVYREGLSAVRIDGG
IAGNVIPDAASVTVNFRFAPDRTVDQALAHVHEVLDGLDVTVEQTDAAAGALPGLTRPAAAALVEAAGGQARAKYGWTDV
ARFAALGIPAVNYGPGDPNLAHRADERVDVGQITATTEVLRRYLTA
>Mature_365_residues
APSSALRASGSSLDLRGDPVELTAALVDIPSESRHEQRIADEIEAALREQTDGFEIIRNGDAVLARTNRGLPSRVLLAGH
IDTVPAADNVPSRRVGDELHGCGTSDMKSGDAVFLHLAATVADPAHDLTLVMYDCEEIEASANGLGRIERELPEWLQADV
AILGEPSGGFIEAGCQGTLRVVVSATGTRAHSARSWLGDNAIHKLGAVLDRLAAYQARSIDIDGCVYREGLSAVRIDGGI
AGNVIPDAASVTVNFRFAPDRTVDQALAHVHEVLDGLDVTVEQTDAAAGALPGLTRPAAAALVEAAGGQARAKYGWTDVA
RFAALGIPAVNYGPGDPNLAHRADERVDVGQITATTEVLRRYLTA

Specific function: Displays A Broad Specificity And Can Also Deacylate Substrates Such As Acetylarginine, Acetylhistidine Or Acetylglutamate Semialdehyde. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family [H]

Homologues:

Organism=Escherichia coli, GI1790395, Length=376, Percent_Identity=28.1914893617021, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001261
- InterPro:   IPR002933
- InterPro:   IPR011650
- InterPro:   IPR010174 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.18 [H]

Molecular weight: Translated: 38424; Mature: 38293

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: PS00758 ARGE_DAPE_CPG2_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPSSALRASGSSLDLRGDPVELTAALVDIPSESRHEQRIADEIEAALREQTDGFEIIRN
CCCCHHHHCCCCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCEEEEEC
GDAVLARTNRGLPSRVLLAGHIDTVPAADNVPSRRVGDELHGCGTSDMKSGDAVFLHLAA
CCEEEEECCCCCCCEEEEEECCCCCCCCCCCCCHHHCHHHHCCCCCCCCCCCEEEEEEEH
TVADPAHDLTLVMYDCEEIEASANGLGRIERELPEWLQADVAILGEPSGGFIEAGCQGTL
HHCCCCCCEEEEEEEHHHHHHHHCHHHHHHHHHHHHHHCCEEEEECCCCCEEECCCCCEE
RVVVSATGTRAHSARSWLGDNAIHKLGAVLDRLAAYQARSIDIDGCVYREGLSAVRIDGG
EEEEEECCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCEEEECCC
IAGNVIPDAASVTVNFRFAPDRTVDQALAHVHEVLDGLDVTVEQTDAAAGALPGLTRPAA
CCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHCCCCEEEECCCCHHCCCCCCCCHHH
AALVEAAGGQARAKYGWTDVARFAALGIPAVNYGPGDPNLAHRADERVDVGQITATTEVL
HHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHCCCCCCCCHHHHHHHHH
RRYLTA
HHHHCC
>Mature Secondary Structure 
APSSALRASGSSLDLRGDPVELTAALVDIPSESRHEQRIADEIEAALREQTDGFEIIRN
CCCHHHHCCCCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCEEEEEC
GDAVLARTNRGLPSRVLLAGHIDTVPAADNVPSRRVGDELHGCGTSDMKSGDAVFLHLAA
CCEEEEECCCCCCCEEEEEECCCCCCCCCCCCCHHHCHHHHCCCCCCCCCCCEEEEEEEH
TVADPAHDLTLVMYDCEEIEASANGLGRIERELPEWLQADVAILGEPSGGFIEAGCQGTL
HHCCCCCCEEEEEEEHHHHHHHHCHHHHHHHHHHHHHHCCEEEEECCCCCEEECCCCCEE
RVVVSATGTRAHSARSWLGDNAIHKLGAVLDRLAAYQARSIDIDGCVYREGLSAVRIDGG
EEEEEECCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCEEEECCC
IAGNVIPDAASVTVNFRFAPDRTVDQALAHVHEVLDGLDVTVEQTDAAAGALPGLTRPAA
CCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHCCCCEEEECCCCHHCCCCCCCCHHH
AALVEAAGGQARAKYGWTDVARFAALGIPAVNYGPGDPNLAHRADERVDVGQITATTEVL
HHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHCCCCCCCCHHHHHHHHH
RRYLTA
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7881553; 12948626; 7592354 [H]