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The map label for this gene is irtA [H]

Identifier: 108800929

GI number: 108800929

Start: 4225089

End: 4225805

Strand: Reverse

Name: irtA [H]

Synonym: Mmcs_3965

Alternate gene names: 108800929

Gene position: 4225805-4225089 (Counterclockwise)

Preceding gene: 108800930

Following gene: 108800928

Centisome position: 74.07

GC content: 68.9

Gene sequence:

>717_bases
ATGGCCGACAGGAAGCCGTCGCGCGGGTTCAGCGGCGCCGTGCTCAAGCTGATGCGCGCCGGCGACTACACGTTCACGGT
CACCGGTAAGCGTGAGATCGGCCCCTACTACCTGCGGCTCAGCTTCACCGCCGGGGGCATGCTCGCCGAGCACGCGCCAC
ACCCGACGCAGTGGGTGCGGGTGTGGTTCGCCGACGGCGACAAACAGCATCAGCGCGGCTACACCCTGGTCAACCCCGAC
CCGTCCGGTGACACCGTCGACATCGAATTCGCGCTGCACGACGGTGTGGCGTCGCAGTGGGCGCGCGACGCGCGGCCCGG
CGACACACTCGAGATCACCGTCCTCGGCAGCAATTTCGCACTGCCCGTACCGCGTCCGGCCGGTTACGTGATCGTCGGCG
ACACCGCGTCGCTGCCCGCGATCAACTCGCTGCTGGCCGCCATCGGTGACGCCCCGGCGCAGGTGTTCCTCGAGGCAGGC
CACGAGGAGGACAAGCAACTCCCGGTCGCGCGCACCTCCGACGTCACCTGGGTGGACCGCAAGAACGCCGGAGAGGCGCT
CATCGAGACCGTCGCCGCGGCGGCGTTCGACGCGGCGGACCACTTCGGCTGGGTGGCCTGCGACAACCGCACCACCCGCG
CGGTGTCGAAGGTGTTCCGCGAGGACTACAAGATTCCGAAGAAGGCCATCAAGGCGCAGGCGTACTGGCAGGTCTGA

Upstream 100 bases:

>100_bases
GCCCGGGCTGACACTGCGGCTGCCCCCGCGCCGATCGGACCGCCCTCACCGCTGCTGCGTTAGGTTAAGCTGCCCTAAGT
TGTCTACGAAGGGCGGATGT

Downstream 100 bases:

>100_bases
GGGGCCCGGCGCAGGTGTGACGGCGCGTCGAAAACCCCGAATCGCCGACTCGGTGCGGCATATGGTGGGCCGAACTCGGG
CTCCAAGAGCGTGGTCCGGG

Product: siderophore-interacting protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 237

Protein sequence:

>238_residues
MADRKPSRGFSGAVLKLMRAGDYTFTVTGKREIGPYYLRLSFTAGGMLAEHAPHPTQWVRVWFADGDKQHQRGYTLVNPD
PSGDTVDIEFALHDGVASQWARDARPGDTLEITVLGSNFALPVPRPAGYVIVGDTASLPAINSLLAAIGDAPAQVFLEAG
HEEDKQLPVARTSDVTWVDRKNAGEALIETVAAAAFDAADHFGWVACDNRTTRAVSKVFREDYKIPKKAIKAQAYWQV

Sequences:

>Translated_238_residues
MADRKPSRGFSGAVLKLMRAGDYTFTVTGKREIGPYYLRLSFTAGGMLAEHAPHPTQWVRVWFADGDKQHQRGYTLVNPD
PSGDTVDIEFALHDGVASQWARDARPGDTLEITVLGSNFALPVPRPAGYVIVGDTASLPAINSLLAAIGDAPAQVFLEAG
HEEDKQLPVARTSDVTWVDRKNAGEALIETVAAAAFDAADHFGWVACDNRTTRAVSKVFREDYKIPKKAIKAQAYWQV
>Mature_237_residues
ADRKPSRGFSGAVLKLMRAGDYTFTVTGKREIGPYYLRLSFTAGGMLAEHAPHPTQWVRVWFADGDKQHQRGYTLVNPDP
SGDTVDIEFALHDGVASQWARDARPGDTLEITVLGSNFALPVPRPAGYVIVGDTASLPAINSLLAAIGDAPAQVFLEAGH
EEDKQLPVARTSDVTWVDRKNAGEALIETVAAAAFDAADHFGWVACDNRTTRAVSKVFREDYKIPKKAIKAQAYWQV

Specific function: Part of the ABC transporter complex IrtAB involved in iron import. Transmembrane domains (TMD) form a pore in the membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG2375

COG function: function code P; Siderophore-interacting protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017940
- InterPro:   IPR001140
- InterPro:   IPR011527
- InterPro:   IPR003593
- InterPro:   IPR013113
- InterPro:   IPR017927
- InterPro:   IPR017938
- InterPro:   IPR007037 [H]

Pfam domain/function: PF00664 ABC_membrane; PF00005 ABC_tran; PF08021 FAD_binding_9; PF04954 SIP [H]

EC number: NA

Molecular weight: Translated: 25954; Mature: 25823

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADRKPSRGFSGAVLKLMRAGDYTFTVTGKREIGPYYLRLSFTAGGMLAEHAPHPTQWVR
CCCCCCCCCCCHHHHHHHHCCCEEEEEECCCCCCEEEEEEEECCCCCHHCCCCCCCCEEE
VWFADGDKQHQRGYTLVNPDPSGDTVDIEFALHDGVASQWARDARPGDTLEITVLGSNFA
EEEECCCCHHHCCCEEECCCCCCCEEEEEEEECCCHHHHHHHCCCCCCEEEEEEECCCCC
LPVPRPAGYVIVGDTASLPAINSLLAAIGDAPAQVFLEAGHEEDKQLPVARTSDVTWVDR
CCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCHHHHEECCCCCHHCCCCCCCCCEEEEEC
KNAGEALIETVAAAAFDAADHFGWVACDNRTTRAVSKVFREDYKIPKKAIKAQAYWQV
CCCHHHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHCCCCHHHHCCEEEECC
>Mature Secondary Structure 
ADRKPSRGFSGAVLKLMRAGDYTFTVTGKREIGPYYLRLSFTAGGMLAEHAPHPTQWVR
CCCCCCCCCCHHHHHHHHCCCEEEEEECCCCCCEEEEEEEECCCCCHHCCCCCCCCEEE
VWFADGDKQHQRGYTLVNPDPSGDTVDIEFALHDGVASQWARDARPGDTLEITVLGSNFA
EEEECCCCHHHCCCEEECCCCCCCEEEEEEEECCCHHHHHHHCCCCCCEEEEEEECCCCC
LPVPRPAGYVIVGDTASLPAINSLLAAIGDAPAQVFLEAGHEEDKQLPVARTSDVTWVDR
CCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCHHHHEECCCCCHHCCCCCCCCCEEEEEC
KNAGEALIETVAAAAFDAADHFGWVACDNRTTRAVSKVFREDYKIPKKAIKAQAYWQV
CCCHHHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHCCCCHHHHCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]