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The map label for this gene is 108800913

Identifier: 108800913

GI number: 108800913

Start: 4210525

End: 4211646

Strand: Reverse

Name: 108800913

Synonym: Mmcs_3949

Alternate gene names: NA

Gene position: 4211646-4210525 (Counterclockwise)

Preceding gene: 108800916

Following gene: 108800908

Centisome position: 73.82

GC content: 71.75

Gene sequence:

>1122_bases
GTGACCGAAGCGCGCGACACCGAAGACATCGAGGGGCTCCTCGTCGGGTTGACCGGAACGGCGCGCTCCGAACGCGCCGA
GTTGATCGAGTGGCTGCTCGGCCGTGGATTCACCATGGCGGAGGTGCACGAGGCGATCGCCCCGATGCTGCTCGCCTCGC
GGCGACACGTCGGCGACGACGGCGTCTACGTCTCCGCCCGCGAGACCAGTGAGAAGTTCGGCATCGACCTTGACCTGTTG
CAGCGCGTCCAGCGGGCCATGGGTCTGTCCCGGGAGGACGACCCGGACGCGGTCGTGCACCTGCGCGCCGATGCGGAGGC
CGCCGCCCGCGCCCAGCGGTTCATCGACTTCGGCCTCGACCCGGATCAGGTCGTCCAGGTGGTCCGCGTGCTGTCCGAGG
GGCTGGCGAAGGCCGCCGAGGTGATGCGGTACACCGCGTTCGCGGCCGTGTTGACCCCCGGTGCGACGGAGTTGCAGATC
GCCAAGAAATCCGAGGCGCTGGTTCGGGAACTCGCCCCGATGCTCGGCCCGATGGTCGAGGACATGCTGTTGCTGCAGCT
GCGTCACGCGATGGAGACCGAGGCGGTGTCGGCGACCGAGCGGGCCGAGGGTCTGCCGCTGCCCGGCGCCCGTGAGGTGA
CGGTGATGTTCGCCGATCTGGTCGGGTTCACCCGGCTCGGTGAGGCGGTGCCACCGGAGAAGCTCGAGCAGCTCGCCCGC
CGGCTCGGCGACCTGGCGCGCGAACTCGCGGTGGCGCCGGTGCGGTTCGTCAAGACGATCGGCGACGCGGTGATGCTGGT
CAGCACCGATCCCGCGGCGCTGCTCGAGGCGGCGCTGGCCCTGCTCGACGCCGCCACCAGCGATGCGGAATTCCCCCGGC
TGCGGGTCGGGTTGGCCGTCGGGCAGGCGGTCAGCCGGGCGGGGGACTGGTTCGGCAGCCCGGTCAACCTCGCCAGCCGC
GTCACCGGGGCCGCCCGGCCGGGCACGGTGCTGGTCTCCGAATCGGTCCGCGAGGCCGTGGGCGACGACGAGCGGTTCTC
CTGGTCCTACGCCGGAGCCCGTCACCTCAAGGGCATCAGGGGTGAGGTGAAACTGTTCCGCGCCCGCCGGCCCGGCGGGT
GA

Upstream 100 bases:

>100_bases
CGGGGTGCACCGCCGACGATGGGTGCGAAACCCTGCACCAGGTCCGGTGTGGACATCGCCGACCATGATGCCCGACGCGC
GGCTGGGTATACGTTGTGGC

Downstream 100 bases:

>100_bases
ACCTCACCGCGACGGGGTGAACCGCCGCAGCCGCAGGCTGTTGGTGACCACGAACACCGAGCTGAACGCCATCGCCGCAC
CGGCGATCAACGGGTTGAGC

Product: adenylate/guanylate cyclase

Products: NA

Alternate protein names: ATP pyrophosphate-lyase; Adenylyl cyclase [H]

Number of amino acids: Translated: 373; Mature: 372

Protein sequence:

>373_residues
MTEARDTEDIEGLLVGLTGTARSERAELIEWLLGRGFTMAEVHEAIAPMLLASRRHVGDDGVYVSARETSEKFGIDLDLL
QRVQRAMGLSREDDPDAVVHLRADAEAAARAQRFIDFGLDPDQVVQVVRVLSEGLAKAAEVMRYTAFAAVLTPGATELQI
AKKSEALVRELAPMLGPMVEDMLLLQLRHAMETEAVSATERAEGLPLPGAREVTVMFADLVGFTRLGEAVPPEKLEQLAR
RLGDLARELAVAPVRFVKTIGDAVMLVSTDPAALLEAALALLDAATSDAEFPRLRVGLAVGQAVSRAGDWFGSPVNLASR
VTGAARPGTVLVSESVREAVGDDERFSWSYAGARHLKGIRGEVKLFRARRPGG

Sequences:

>Translated_373_residues
MTEARDTEDIEGLLVGLTGTARSERAELIEWLLGRGFTMAEVHEAIAPMLLASRRHVGDDGVYVSARETSEKFGIDLDLL
QRVQRAMGLSREDDPDAVVHLRADAEAAARAQRFIDFGLDPDQVVQVVRVLSEGLAKAAEVMRYTAFAAVLTPGATELQI
AKKSEALVRELAPMLGPMVEDMLLLQLRHAMETEAVSATERAEGLPLPGAREVTVMFADLVGFTRLGEAVPPEKLEQLAR
RLGDLARELAVAPVRFVKTIGDAVMLVSTDPAALLEAALALLDAATSDAEFPRLRVGLAVGQAVSRAGDWFGSPVNLASR
VTGAARPGTVLVSESVREAVGDDERFSWSYAGARHLKGIRGEVKLFRARRPGG
>Mature_372_residues
TEARDTEDIEGLLVGLTGTARSERAELIEWLLGRGFTMAEVHEAIAPMLLASRRHVGDDGVYVSARETSEKFGIDLDLLQ
RVQRAMGLSREDDPDAVVHLRADAEAAARAQRFIDFGLDPDQVVQVVRVLSEGLAKAAEVMRYTAFAAVLTPGATELQIA
KKSEALVRELAPMLGPMVEDMLLLQLRHAMETEAVSATERAEGLPLPGAREVTVMFADLVGFTRLGEAVPPEKLEQLARR
LGDLARELAVAPVRFVKTIGDAVMLVSTDPAALLEAALALLDAATSDAEFPRLRVGLAVGQAVSRAGDWFGSPVNLASRV
TGAARPGTVLVSESVREAVGDDERFSWSYAGARHLKGIRGEVKLFRARRPGG

Specific function: Catalyzes the formation of the second messenger cAMP [H]

COG id: COG2114

COG function: function code T; Adenylate cyclase, family 3 (some proteins contain HAMP domain)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 guanylate cyclase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054 [H]

Pfam domain/function: PF00211 Guanylate_cyc [H]

EC number: =4.6.1.1 [H]

Molecular weight: Translated: 40167; Mature: 40035

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS50125 GUANYLATE_CYCLASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEARDTEDIEGLLVGLTGTARSERAELIEWLLGRGFTMAEVHEAIAPMLLASRRHVGDD
CCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCC
GVYVSARETSEKFGIDLDLLQRVQRAMGLSREDDPDAVVHLRADAEAAARAQRFIDFGLD
CEEEEECCCHHHHCCCHHHHHHHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHHHCCCC
PDQVVQVVRVLSEGLAKAAEVMRYTAFAAVLTPGATELQIAKKSEALVRELAPMLGPMVE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHH
DMLLLQLRHAMETEAVSATERAEGLPLPGAREVTVMFADLVGFTRLGEAVPPEKLEQLAR
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
RLGDLARELAVAPVRFVKTIGDAVMLVSTDPAALLEAALALLDAATSDAEFPRLRVGLAV
HHHHHHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
GQAVSRAGDWFGSPVNLASRVTGAARPGTVLVSESVREAVGDDERFSWSYAGARHLKGIR
HHHHHHHHHCCCCCHHHHHHHCCCCCCCEEEEHHHHHHHHCCCCCCEEHHCCHHHHHCCH
GEVKLFRARRPGG
HHHHHHCCCCCCC
>Mature Secondary Structure 
TEARDTEDIEGLLVGLTGTARSERAELIEWLLGRGFTMAEVHEAIAPMLLASRRHVGDD
CCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCC
GVYVSARETSEKFGIDLDLLQRVQRAMGLSREDDPDAVVHLRADAEAAARAQRFIDFGLD
CEEEEECCCHHHHCCCHHHHHHHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHHHCCCC
PDQVVQVVRVLSEGLAKAAEVMRYTAFAAVLTPGATELQIAKKSEALVRELAPMLGPMVE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHH
DMLLLQLRHAMETEAVSATERAEGLPLPGAREVTVMFADLVGFTRLGEAVPPEKLEQLAR
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
RLGDLARELAVAPVRFVKTIGDAVMLVSTDPAALLEAALALLDAATSDAEFPRLRVGLAV
HHHHHHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
GQAVSRAGDWFGSPVNLASRVTGAARPGTVLVSESVREAVGDDERFSWSYAGARHLKGIR
HHHHHHHHHCCCCCHHHHHHHCCCCCCCEEEEHHHHHHHHCCCCCCEEHHCCHHHHHCCH
GEVKLFRARRPGG
HHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]