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The map label for this gene is argS [H]

Identifier: 108800862

GI number: 108800862

Start: 4151221

End: 4152873

Strand: Reverse

Name: argS [H]

Synonym: Mmcs_3898

Alternate gene names: 108800862

Gene position: 4152873-4151221 (Counterclockwise)

Preceding gene: 108800863

Following gene: 108800861

Centisome position: 72.79

GC content: 68.91

Gene sequence:

>1653_bases
GTGACACCCGCCGACCTCGCCGACTTGCTCAGGACCACCGCCACCGCTGTGTTGACCGAGCGCGACCTCGACACGGCCGC
GCTGCCCGCGACGGTCACGGTGGAGCGTCCCCGCAATCCGGAGCACGGCGATTACGCCACCAACCTGGCGTTGCAGGTCG
GCAAGAAGGTCGGCGTGAACCCGCGCGAACTGGCGGGATGGCTCGCCGAGGCGCTGACGGCCACCGCGGGCATCGCCTCG
GCCGAGGTGGCCGGCCCGGGTTTCGTCAACCTGCGCATCGAGGCGGCGGCCCAGAACGTGATCGTCGGCGACATCATCAC
GAGTGCCGAGCGTTACGGACACTCCGCCGCGCTGGCCGAGCGCAACATCAACCTCGAATTCGTCTCGGCCAACCCCACCG
GCCCCATCCACATCGGCGGCACCCGGTGGGCCGCCGTCGGCGATGCGCTGGGCCGGCTGCTGGCCACTCAGGGCGCCGCG
GTGGTGCGGGAGTATTACTTCAACGACCACGGCGCGCAGATCGACCGGTTCGTCAGCTCGCTGATCGCCGCGGCCAAGGG
AGAGCCCACCCCCGAGGACGGCTACGCAGGCAGCTACATCGGCGATATCGCGGCGCAGGTTCTCGCCAAGGATCCGGGTG
CGCTCGAACTGCCCGACGACGAGATGCGGGAGACCTTCCGCGCCATCGGCGTCGACCTGATGTTCGACCACATCAAGATC
TCGCTGCACGACTTCGGCACGGACTTCGACGTGTTCACCCACGAAGACTCGATGCACACCAGCGGACGGGTCGAGGAGGC
GATCGCCCGGCTGCGGGAGAACGGCGCGATCTATGAGAAGGACGGCGCCACCTGGCTGCGCACCACCGACTTCGGGGACG
ACAAGGACCGCGTCGTCATCAAGAGCGACGGCGCCCCCGCCTACATCGCCGGTGACCTCGCCTACTTCCTGGACAAACGG
CAGCGCGGATTCGACCTGTGCATCTACATGCTCGGTGCGGACCACCACGGCTACATCGCCCGACTCAAGGCCGCCGCGGC
GGCGCTCGGCGACGATCCGGACACCGTCGAGGTGATGATCGGCCAGATGGTCAACCTGGTGCGCGACGGTCAACCGGTGC
GGATGAGCAAGCGCGCCGGCACCGTGATCACCCTCGACGATCTGGTCGAGGCGATCGGCGTCGACGCCGCGCGGTACTCG
TTGATCCGCTCCTCGGTGGACACCCCGATCGACATCGACCTGGCGCTGTGGTCCTCGGCGTCCAACGAGAACCCGGTCTA
CTACGTGCAGTACGCCCACGCACGGCTGTCGGCGCTGGCCCGCAACGCGGCCGACCTCGGCGTCGTCGCCGACACCGCGC
ACCTCGACCTGCTCACGCACGACAAAGAGGGCACGCTCATCCGCAACCTCGGCGAGTTCCCGCGGGTGCTGGAGTCGGCG
GCCGCGCTGCGCGAACCGCACCGGGTGTGCCGCTACCTCGAGGACCTCGCCGGTGACTACCACCGGTTCTACGACTCCTG
CCGCGTGCTGCCGCAGGGCGATGAGGCTCCGGGCAGCCTTCATCAGGCCCGCCTGGCGCTGTGTCAGGCCACCCGTCAGG
TGATCGCCAACGGTCTGGCGATACTCGGCGTGAGCGCCCCGGAGCGGATGTGA

Upstream 100 bases:

>100_bases
GTTCAGACGTACCGCGCCATTGGGCGTGCACAGCGTAACGCATCACGGCCCGAGGAATGGATTCGGGCACTGACCACCCC
AGACCATAGGATGGACCCCC

Downstream 100 bases:

>100_bases
ACGCCCACCCCGCCGGCCCCCGGCACGCCGAGGAGATCCACCACGGCGGCGCGCCACCGCGTCCCGCCGGACCCGACGAG
GTCCTGCGGCTGGCCCCGAA

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS [H]

Number of amino acids: Translated: 550; Mature: 549

Protein sequence:

>550_residues
MTPADLADLLRTTATAVLTERDLDTAALPATVTVERPRNPEHGDYATNLALQVGKKVGVNPRELAGWLAEALTATAGIAS
AEVAGPGFVNLRIEAAAQNVIVGDIITSAERYGHSAALAERNINLEFVSANPTGPIHIGGTRWAAVGDALGRLLATQGAA
VVREYYFNDHGAQIDRFVSSLIAAAKGEPTPEDGYAGSYIGDIAAQVLAKDPGALELPDDEMRETFRAIGVDLMFDHIKI
SLHDFGTDFDVFTHEDSMHTSGRVEEAIARLRENGAIYEKDGATWLRTTDFGDDKDRVVIKSDGAPAYIAGDLAYFLDKR
QRGFDLCIYMLGADHHGYIARLKAAAAALGDDPDTVEVMIGQMVNLVRDGQPVRMSKRAGTVITLDDLVEAIGVDAARYS
LIRSSVDTPIDIDLALWSSASNENPVYYVQYAHARLSALARNAADLGVVADTAHLDLLTHDKEGTLIRNLGEFPRVLESA
AALREPHRVCRYLEDLAGDYHRFYDSCRVLPQGDEAPGSLHQARLALCQATRQVIANGLAILGVSAPERM

Sequences:

>Translated_550_residues
MTPADLADLLRTTATAVLTERDLDTAALPATVTVERPRNPEHGDYATNLALQVGKKVGVNPRELAGWLAEALTATAGIAS
AEVAGPGFVNLRIEAAAQNVIVGDIITSAERYGHSAALAERNINLEFVSANPTGPIHIGGTRWAAVGDALGRLLATQGAA
VVREYYFNDHGAQIDRFVSSLIAAAKGEPTPEDGYAGSYIGDIAAQVLAKDPGALELPDDEMRETFRAIGVDLMFDHIKI
SLHDFGTDFDVFTHEDSMHTSGRVEEAIARLRENGAIYEKDGATWLRTTDFGDDKDRVVIKSDGAPAYIAGDLAYFLDKR
QRGFDLCIYMLGADHHGYIARLKAAAAALGDDPDTVEVMIGQMVNLVRDGQPVRMSKRAGTVITLDDLVEAIGVDAARYS
LIRSSVDTPIDIDLALWSSASNENPVYYVQYAHARLSALARNAADLGVVADTAHLDLLTHDKEGTLIRNLGEFPRVLESA
AALREPHRVCRYLEDLAGDYHRFYDSCRVLPQGDEAPGSLHQARLALCQATRQVIANGLAILGVSAPERM
>Mature_549_residues
TPADLADLLRTTATAVLTERDLDTAALPATVTVERPRNPEHGDYATNLALQVGKKVGVNPRELAGWLAEALTATAGIASA
EVAGPGFVNLRIEAAAQNVIVGDIITSAERYGHSAALAERNINLEFVSANPTGPIHIGGTRWAAVGDALGRLLATQGAAV
VREYYFNDHGAQIDRFVSSLIAAAKGEPTPEDGYAGSYIGDIAAQVLAKDPGALELPDDEMRETFRAIGVDLMFDHIKIS
LHDFGTDFDVFTHEDSMHTSGRVEEAIARLRENGAIYEKDGATWLRTTDFGDDKDRVVIKSDGAPAYIAGDLAYFLDKRQ
RGFDLCIYMLGADHHGYIARLKAAAAALGDDPDTVEVMIGQMVNLVRDGQPVRMSKRAGTVITLDDLVEAIGVDAARYSL
IRSSVDTPIDIDLALWSSASNENPVYYVQYAHARLSALARNAADLGVVADTAHLDLLTHDKEGTLIRNLGEFPRVLESAA
ALREPHRVCRYLEDLAGDYHRFYDSCRVLPQGDEAPGSLHQARLALCQATRQVIANGLAILGVSAPERM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI15149476, Length=587, Percent_Identity=26.2350936967632, Blast_Score=116, Evalue=7e-26,
Organism=Escherichia coli, GI1788184, Length=567, Percent_Identity=25.9259259259259, Blast_Score=132, Evalue=6e-32,
Organism=Caenorhabditis elegans, GI71985061, Length=580, Percent_Identity=23.448275862069, Blast_Score=99, Evalue=8e-21,
Organism=Saccharomyces cerevisiae, GI6320548, Length=609, Percent_Identity=25.4515599343186, Blast_Score=135, Evalue=1e-32,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d [H]

EC number: =6.1.1.19 [H]

Molecular weight: Translated: 59279; Mature: 59148

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPADLADLLRTTATAVLTERDLDTAALPATVTVERPRNPEHGDYATNLALQVGKKVGVN
CCHHHHHHHHHHHHHHHHHHCCCCCHHCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCC
PRELAGWLAEALTATAGIASAEVAGPGFVNLRIEAAAQNVIVGDIITSAERYGHSAALAE
HHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCEEEHHHHHHHHHHCCHHHHHH
RNINLEFVSANPTGPIHIGGTRWAAVGDALGRLLATQGAAVVREYYFNDHGAQIDRFVSS
CCCCEEEEECCCCCCEEECCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHH
LIAAAKGEPTPEDGYAGSYIGDIAAQVLAKDPGALELPDDEMRETFRAIGVDLMFDHIKI
HHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHEEEEEEEE
SLHDFGTDFDVFTHEDSMHTSGRVEEAIARLRENGAIYEKDGATWLRTTDFGDDKDRVVI
EEECCCCCCEEEECCCCCCCCCHHHHHHHHHHHCCCEEECCCCEEEEECCCCCCCCEEEE
KSDGAPAYIAGDLAYFLDKRQRGFDLCIYMLGADHHGYIARLKAAAAALGDDPDTVEVMI
ECCCCCEEEHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCCCHHHHHH
GQMVNLVRDGQPVRMSKRAGTVITLDDLVEAIGVDAARYSLIRSSVDTPIDIDLALWSSA
HHHHHHHHCCCCCEECCCCCCEEEHHHHHHHHCCCHHHHHHHHHCCCCCEEEEEEEECCC
SNENPVYYVQYAHARLSALARNAADLGVVADTAHLDLLTHDKEGTLIRNLGEFPRVLESA
CCCCCEEEEEEHHHHHHHHHHCCCCCCEEECCCEEEEEEECCCCHHHHHHHHHHHHHHHH
AALREPHRVCRYLEDLAGDYHRFYDSCRVLPQGDEAPGSLHQARLALCQATRQVIANGLA
HHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEE
ILGVSAPERM
EEECCCCCCC
>Mature Secondary Structure 
TPADLADLLRTTATAVLTERDLDTAALPATVTVERPRNPEHGDYATNLALQVGKKVGVN
CHHHHHHHHHHHHHHHHHHCCCCCHHCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCC
PRELAGWLAEALTATAGIASAEVAGPGFVNLRIEAAAQNVIVGDIITSAERYGHSAALAE
HHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCEEEHHHHHHHHHHCCHHHHHH
RNINLEFVSANPTGPIHIGGTRWAAVGDALGRLLATQGAAVVREYYFNDHGAQIDRFVSS
CCCCEEEEECCCCCCEEECCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHH
LIAAAKGEPTPEDGYAGSYIGDIAAQVLAKDPGALELPDDEMRETFRAIGVDLMFDHIKI
HHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHEEEEEEEE
SLHDFGTDFDVFTHEDSMHTSGRVEEAIARLRENGAIYEKDGATWLRTTDFGDDKDRVVI
EEECCCCCCEEEECCCCCCCCCHHHHHHHHHHHCCCEEECCCCEEEEECCCCCCCCEEEE
KSDGAPAYIAGDLAYFLDKRQRGFDLCIYMLGADHHGYIARLKAAAAALGDDPDTVEVMI
ECCCCCEEEHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCCCHHHHHH
GQMVNLVRDGQPVRMSKRAGTVITLDDLVEAIGVDAARYSLIRSSVDTPIDIDLALWSSA
HHHHHHHHCCCCCEECCCCCCEEEHHHHHHHHCCCHHHHHHHHHCCCCCEEEEEEEECCC
SNENPVYYVQYAHARLSALARNAADLGVVADTAHLDLLTHDKEGTLIRNLGEFPRVLESA
CCCCCEEEEEEHHHHHHHHHHCCCCCCEEECCCEEEEEEECCCCHHHHHHHHHHHHHHHH
AALREPHRVCRYLEDLAGDYHRFYDSCRVLPQGDEAPGSLHQARLALCQATRQVIANGLA
HHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEE
ILGVSAPERM
EEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA