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The map label for this gene is lysA [H]

Identifier: 108800861

GI number: 108800861

Start: 4149800

End: 4151224

Strand: Reverse

Name: lysA [H]

Synonym: Mmcs_3897

Alternate gene names: 108800861

Gene position: 4151224-4149800 (Counterclockwise)

Preceding gene: 108800862

Following gene: 108800860

Centisome position: 72.76

GC content: 70.39

Gene sequence:

>1425_bases
GTGAACGCCCACCCCGCCGGCCCCCGGCACGCCGAGGAGATCCACCACGGCGGCGCGCCACCGCGTCCCGCCGGACCCGA
CGAGGTCCTGCGGCTGGCCCCGAATGTGTGGCCGCGCAACGCCGTTCGCGGCGCCGACGGTGTCGTGTCGATCGCCGGGG
TGCCCGTCACCGACATCGCGGCCCAGTTCGGCACGCCGGTTTTCATCATCGACGAGGCCGACTTCCGCTCGCGCTGCCGG
GAGATCTCCGCCGCGTTCGGTGGCGGCGAGTACGTGCGCTACGCCGCAAAGGCTTTCCTGTGCACCGAGGTGGCGCGCTG
GATCGACGAGGAGGGGCTCGCCCTCGACGTCGCCAGTGGCGGAGAACTCGCGGTCGCGTTGCACGCCGGCTTCCCGGCCG
AGCGGATCGCGTTGCACGGCAACAACAAATCGCCGGACGAACTGGCGCTGGCCGTGAAGTCCGGCGTGGGCCACGTGGTG
GTCGACTCGATGATCGAGATCGAACGCCTCGACGAGATCGCCGCCGCGGCGGGCGTGGTCCAGGACGTGCTGGTGCGGGT
GACCGTCGGCGTCGAAGCCCATACGCACGAGTTCATCTCGACCGCGCACGAGGACCAGAAGTTCGGGCTCTCGCTGGCCA
GCGGGGCCGCGATGGCCGCCGTGCGCCGCGTGTTCGAGACCGACAACCTGCGGTTGGTCGGCCTGCACAGCCACATCGGC
TCGCAGATCTTCGACGTCGCGGGGTTCGAGCTCGCCGCGCACCGCGTGATCGGCCTGCTGCGCGATGTCGTCGCCGAATT
CGGGGTGGACAAGACCGCCCAGATGTCCACCGTCGACCTCGGTGGTGGCCTCGGCATCTCCTATCTGCCGCAGGACGATC
CGCCGCCGGTCGCCGACCTCGCCGCCAAGCTGAGCGCCATCGTGCGCGAGGAGTCGGCAGCCGTCGGGCTGCCCACCCCG
AAACTCGTGGTCGAGCCGGGCCGGGCGATCGCCGGGCCGGGCACGATCACGCTCTACGAGGTCGGCACCGTCAAGGACGT
GGCCGTGGCGTCGGACAGGTACCGCCGCTACGTCAGCGTCGACGGCGGGATGAGCGACAACATCCGCACCTCGCTCTACG
GCGCCGAATACGACGTCCGGTTGGTCTCCCGGGTCAGCGACGCCGACCCCGCACTGAGCCGCGTGGTCGGAAAGCACTGC
GAGAGCGGCGACATCGTGGTCCGGGACGCCTGGCTCTCCGGTGATGTGGCACCGGGCGATCTGCTCGGGGTGGCCGCGAC
CGGCGCCTACTGCTATTCGATGTCGAGCCGTTACAACCTGATCGGCCGCCCCGCGGTGGTGGCGGTGCGCGACGGGCACG
CGCGCCTGATCCTGCGCCGCGAGACGGTCGACGATCTGTTGAGTCTGGAAGTGAGTGGTCAATGA

Upstream 100 bases:

>100_bases
CGGGCAGCCTTCATCAGGCCCGCCTGGCGCTGTGTCAGGCCACCCGTCAGGTGATCGCCAACGGTCTGGCGATACTCGGC
GTGAGCGCCCCGGAGCGGAT

Downstream 100 bases:

>100_bases
ACAGTGACAAATCGGTAGGCGACACACCGGTGGGCGTAGCCGTCCTGGGCCTCGGCAATGTGGGCAGTGAAGTGGTCCAC
ATCATCGAGCAGAGCGCGAC

Product: diaminopimelate decarboxylase

Products: NA

Alternate protein names: DAP decarboxylase [H]

Number of amino acids: Translated: 474; Mature: 474

Protein sequence:

>474_residues
MNAHPAGPRHAEEIHHGGAPPRPAGPDEVLRLAPNVWPRNAVRGADGVVSIAGVPVTDIAAQFGTPVFIIDEADFRSRCR
EISAAFGGGEYVRYAAKAFLCTEVARWIDEEGLALDVASGGELAVALHAGFPAERIALHGNNKSPDELALAVKSGVGHVV
VDSMIEIERLDEIAAAAGVVQDVLVRVTVGVEAHTHEFISTAHEDQKFGLSLASGAAMAAVRRVFETDNLRLVGLHSHIG
SQIFDVAGFELAAHRVIGLLRDVVAEFGVDKTAQMSTVDLGGGLGISYLPQDDPPPVADLAAKLSAIVREESAAVGLPTP
KLVVEPGRAIAGPGTITLYEVGTVKDVAVASDRYRRYVSVDGGMSDNIRTSLYGAEYDVRLVSRVSDADPALSRVVGKHC
ESGDIVVRDAWLSGDVAPGDLLGVAATGAYCYSMSSRYNLIGRPAVVAVRDGHARLILRRETVDDLLSLEVSGQ

Sequences:

>Translated_474_residues
MNAHPAGPRHAEEIHHGGAPPRPAGPDEVLRLAPNVWPRNAVRGADGVVSIAGVPVTDIAAQFGTPVFIIDEADFRSRCR
EISAAFGGGEYVRYAAKAFLCTEVARWIDEEGLALDVASGGELAVALHAGFPAERIALHGNNKSPDELALAVKSGVGHVV
VDSMIEIERLDEIAAAAGVVQDVLVRVTVGVEAHTHEFISTAHEDQKFGLSLASGAAMAAVRRVFETDNLRLVGLHSHIG
SQIFDVAGFELAAHRVIGLLRDVVAEFGVDKTAQMSTVDLGGGLGISYLPQDDPPPVADLAAKLSAIVREESAAVGLPTP
KLVVEPGRAIAGPGTITLYEVGTVKDVAVASDRYRRYVSVDGGMSDNIRTSLYGAEYDVRLVSRVSDADPALSRVVGKHC
ESGDIVVRDAWLSGDVAPGDLLGVAATGAYCYSMSSRYNLIGRPAVVAVRDGHARLILRRETVDDLLSLEVSGQ
>Mature_474_residues
MNAHPAGPRHAEEIHHGGAPPRPAGPDEVLRLAPNVWPRNAVRGADGVVSIAGVPVTDIAAQFGTPVFIIDEADFRSRCR
EISAAFGGGEYVRYAAKAFLCTEVARWIDEEGLALDVASGGELAVALHAGFPAERIALHGNNKSPDELALAVKSGVGHVV
VDSMIEIERLDEIAAAAGVVQDVLVRVTVGVEAHTHEFISTAHEDQKFGLSLASGAAMAAVRRVFETDNLRLVGLHSHIG
SQIFDVAGFELAAHRVIGLLRDVVAEFGVDKTAQMSTVDLGGGLGISYLPQDDPPPVADLAAKLSAIVREESAAVGLPTP
KLVVEPGRAIAGPGTITLYEVGTVKDVAVASDRYRRYVSVDGGMSDNIRTSLYGAEYDVRLVSRVSDADPALSRVVGKHC
ESGDIVVRDAWLSGDVAPGDLLGVAATGAYCYSMSSRYNLIGRPAVVAVRDGHARLILRRETVDDLLSLEVSGQ

Specific function: Lysine biosynthesis; last step. [C]

COG id: COG0019

COG function: function code E; Diaminopimelate decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-II family [H]

Homologues:

Organism=Escherichia coli, GI1789203, Length=431, Percent_Identity=29.6983758700696, Blast_Score=126, Evalue=3e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009006
- InterPro:   IPR002986
- InterPro:   IPR022643
- InterPro:   IPR022657
- InterPro:   IPR022644
- InterPro:   IPR022653
- InterPro:   IPR000183 [H]

Pfam domain/function: PF02784 Orn_Arg_deC_N; PF00278 Orn_DAP_Arg_deC [H]

EC number: =4.1.1.20 [H]

Molecular weight: Translated: 49956; Mature: 49956

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS00878 ODR_DC_2_1 ; PS00879 ODR_DC_2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAHPAGPRHAEEIHHGGAPPRPAGPDEVLRLAPNVWPRNAVRGADGVVSIAGVPVTDIA
CCCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCEEEECCCCHHHHH
AQFGTPVFIIDEADFRSRCREISAAFGGGEYVRYAAKAFLCTEVARWIDEEGLALDVASG
HHHCCCEEEEECCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCC
GELAVALHAGFPAERIALHGNNKSPDELALAVKSGVGHVVVDSMIEIERLDEIAAAAGVV
CCEEEEEECCCCHHEEEEECCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
QDVLVRVTVGVEAHTHEFISTAHEDQKFGLSLASGAAMAAVRRVFETDNLRLVGLHSHIG
HHHHHHHEECCCHHHHHHHHHHCCCHHCCCCHHCCHHHHHHHHHHHCCCEEEEEEHHHHC
SQIFDVAGFELAAHRVIGLLRDVVAEFGVDKTAQMSTVDLGGGLGISYLPQDDPPPVADL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHH
AAKLSAIVREESAAVGLPTPKLVVEPGRAIAGPGTITLYEVGTVKDVAVASDRYRRYVSV
HHHHHHHHHHCCCCCCCCCCCEEECCCCEECCCCEEEEEECCCCCHHHHHHHHCEEEEEE
DGGMSDNIRTSLYGAEYDVRLVSRVSDADPALSRVVGKHCESGDIVVRDAWLSGDVAPGD
CCCCCCCCEEEEECCCCCHHHHHHCCCCCHHHHHHHHHCCCCCCEEEEEEECCCCCCCCH
LLGVAATGAYCYSMSSRYNLIGRPAVVAVRDGHARLILRRETVDDLLSLEVSGQ
HEEHHHCCCEEEECCCCCCCCCCCEEEEEECCCEEEEEEHHHHHHHHEEEECCC
>Mature Secondary Structure
MNAHPAGPRHAEEIHHGGAPPRPAGPDEVLRLAPNVWPRNAVRGADGVVSIAGVPVTDIA
CCCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCEEEECCCCHHHHH
AQFGTPVFIIDEADFRSRCREISAAFGGGEYVRYAAKAFLCTEVARWIDEEGLALDVASG
HHHCCCEEEEECCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCC
GELAVALHAGFPAERIALHGNNKSPDELALAVKSGVGHVVVDSMIEIERLDEIAAAAGVV
CCEEEEEECCCCHHEEEEECCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
QDVLVRVTVGVEAHTHEFISTAHEDQKFGLSLASGAAMAAVRRVFETDNLRLVGLHSHIG
HHHHHHHEECCCHHHHHHHHHHCCCHHCCCCHHCCHHHHHHHHHHHCCCEEEEEEHHHHC
SQIFDVAGFELAAHRVIGLLRDVVAEFGVDKTAQMSTVDLGGGLGISYLPQDDPPPVADL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHH
AAKLSAIVREESAAVGLPTPKLVVEPGRAIAGPGTITLYEVGTVKDVAVASDRYRRYVSV
HHHHHHHHHHCCCCCCCCCCCEEECCCCEECCCCEEEEEECCCCCHHHHHHHHCEEEEEE
DGGMSDNIRTSLYGAEYDVRLVSRVSDADPALSRVVGKHCESGDIVVRDAWLSGDVAPGD
CCCCCCCCEEEEECCCCCHHHHHHCCCCCHHHHHHHHHCCCCCCEEEEEEECCCCCCCCH
LLGVAATGAYCYSMSSRYNLIGRPAVVAVRDGHARLILRRETVDDLLSLEVSGQ
HEEHHHCCCEEEECCCCCCCCCCCEEEEEECCCEEEEEEHHHHHHHHEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA