Click here to switch to the map view.

The map label for this gene is 108800811

Identifier: 108800811

GI number: 108800811

Start: 4092393

End: 4093082

Strand: Reverse

Name: 108800811

Synonym: Mmcs_3847

Alternate gene names: NA

Gene position: 4093082-4092393 (Counterclockwise)

Preceding gene: 108800812

Following gene: 108800810

Centisome position: 71.74

GC content: 69.13

Gene sequence:

>690_bases
ATGGGCGTGACGGGGCCGACGGGGTCTCCCGCGTACCCGGCGCCGTCCAGCAAGCGGCCCGCCTGGATCGTCGGCGGCGC
CACGATCGTCAGCTTCGTCGTCCTGCTCTACGTCATCGAACTGGTCGATTCGCTCACCGGGCACCGGCTCGACGAGAACG
GCATCCGCCCGCTGGAGACCGACGGCCTGTGGGGCATCGTCTTCTCGCCGCTGCTGCACGCCGACTGGCAACACCTGCTC
GCCAACACCGGTCCCGCGCTGGTGCTCGGGTTCCTGATGACCCTGGCCGGGCTGTCCCGGTTCATCTACGCGACGGCCAT
CGTGTGGATCCTCGGCGGCCTCGGCACCTGGCTGATCGGGAACCTCGGCACGCACTGCCCCTATGTCGGCGTGCGCTGCG
AGGTCAACCACATCGGTGCGTCCGGCCTGATCTTCGGCTGGCTGGCCTTCCTGATCGTGTTCGGCTTCTTCACGCGCAAG
GCCTGGGAGATCGTCGTCGGGGTCATCGTGTTGTTCGTCTACGGCGGCATCCTGCTCGGCGTGCTGCCCGGCACCCCGGG
AGTGTCCTGGCAGGGACACCTGTGCGGTGCGGTCGCCGGGGTCGTCGCCGCCTACGTCCTGTCCAGTCCGGAACGCAAGG
CCCGCGAACTTCGCCGGTCGCGGACCGCTCCGCCGTACCTGACCTCGTGA

Upstream 100 bases:

>100_bases
ACATCGCGTTCACCGTGTGTGACGCCGGCTGGAAGTATCTGTCGACCGGTGCGTACACCGGTAGCCTCGTCGACGCAGAG
GACGCGTTGGAAGGGCAGCT

Downstream 100 bases:

>100_bases
CCGACGCGGTGGACGATCGGCTGCTGCCCGTCGGGATCTTCGATTCCGGTGTCGGGGGGCTCACGGTCGCGCGGGCGATC
ATCGACCAGCTGCCCGACGA

Product: rhomboid-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 228

Protein sequence:

>229_residues
MGVTGPTGSPAYPAPSSKRPAWIVGGATIVSFVVLLYVIELVDSLTGHRLDENGIRPLETDGLWGIVFSPLLHADWQHLL
ANTGPALVLGFLMTLAGLSRFIYATAIVWILGGLGTWLIGNLGTHCPYVGVRCEVNHIGASGLIFGWLAFLIVFGFFTRK
AWEIVVGVIVLFVYGGILLGVLPGTPGVSWQGHLCGAVAGVVAAYVLSSPERKARELRRSRTAPPYLTS

Sequences:

>Translated_229_residues
MGVTGPTGSPAYPAPSSKRPAWIVGGATIVSFVVLLYVIELVDSLTGHRLDENGIRPLETDGLWGIVFSPLLHADWQHLL
ANTGPALVLGFLMTLAGLSRFIYATAIVWILGGLGTWLIGNLGTHCPYVGVRCEVNHIGASGLIFGWLAFLIVFGFFTRK
AWEIVVGVIVLFVYGGILLGVLPGTPGVSWQGHLCGAVAGVVAAYVLSSPERKARELRRSRTAPPYLTS
>Mature_228_residues
GVTGPTGSPAYPAPSSKRPAWIVGGATIVSFVVLLYVIELVDSLTGHRLDENGIRPLETDGLWGIVFSPLLHADWQHLLA
NTGPALVLGFLMTLAGLSRFIYATAIVWILGGLGTWLIGNLGTHCPYVGVRCEVNHIGASGLIFGWLAFLIVFGFFTRKA
WEIVVGVIVLFVYGGILLGVLPGTPGVSWQGHLCGAVAGVVAAYVLSSPERKARELRRSRTAPPYLTS

Specific function: Unknown

COG id: COG0705

COG function: function code R; Uncharacterized membrane protein (homolog of Drosophila rhomboid)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To M.leprae ML1171 [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022764 [H]

Pfam domain/function: PF01694 Rhomboid [H]

EC number: NA

Molecular weight: Translated: 24406; Mature: 24275

Theoretical pI: Translated: 8.82; Mature: 8.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGVTGPTGSPAYPAPSSKRPAWIVGGATIVSFVVLLYVIELVDSLTGHRLDENGIRPLET
CCCCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
DGLWGIVFSPLLHADWQHLLANTGPALVLGFLMTLAGLSRFIYATAIVWILGGLGTWLIG
CCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NLGTHCPYVGVRCEVNHIGASGLIFGWLAFLIVFGFFTRKAWEIVVGVIVLFVYGGILLG
HCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLPGTPGVSWQGHLCGAVAGVVAAYVLSSPERKARELRRSRTAPPYLTS
HCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
GVTGPTGSPAYPAPSSKRPAWIVGGATIVSFVVLLYVIELVDSLTGHRLDENGIRPLET
CCCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
DGLWGIVFSPLLHADWQHLLANTGPALVLGFLMTLAGLSRFIYATAIVWILGGLGTWLIG
CCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NLGTHCPYVGVRCEVNHIGASGLIFGWLAFLIVFGFFTRKAWEIVVGVIVLFVYGGILLG
HCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLPGTPGVSWQGHLCGAVAGVVAAYVLSSPERKARELRRSRTAPPYLTS
HCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]