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The map label for this gene is lmrB [H]

Identifier: 108800806

GI number: 108800806

Start: 4087311

End: 4089242

Strand: Reverse

Name: lmrB [H]

Synonym: Mmcs_3842

Alternate gene names: 108800806

Gene position: 4089242-4087311 (Counterclockwise)

Preceding gene: 108800807

Following gene: 108800802

Centisome position: 71.67

GC content: 71.38

Gene sequence:

>1932_bases
GTGGCTCGGCACGGTGTGGAGACGTCAGCGGCGGATGCGGCGGCGGTGGCCGCCCGGGTCCGCCCGAACGTGCTCGTCGC
CGTCCTCGCGGCCGCAGGCATCAGCGTGTCGCTGATGCAGACGCTGATCATCCCGCTGATCCCGGAACTGCCGACCCTGT
TGCGGACCGGTCCGGCCAACGCATCCTGGGCCATCACCGCGACACTGCTCACCGCGGCCGTCGCGACGCCGCTGTTCGGC
CGGCTCGGCGACATCTACGGACCCAAACCCGTGCTGATGACCTGTGCGGCGCTGCTGACGGCGGGTTCGGTGATCGCGGC
GGTCAGCACCTCGCTCGTCCCGGTGATCGTCGGCCGCGGGCTGCAAGGATTCGGGATGCCGATCATCCCGCTGGGGATCA
GCGTGCTGCGCGCGGCGGTCCCCGCCGACCGGGTGGGTTCGGCGATGGGCATCATGAGCGCCTCGCTCGGGGTGGGTGGT
GCCCTGGGCCTGCCGTTGTCGGCGGTGATCGCGCAGAACTTCAACTGGCACGTGCTGTTTTGGTTCGCCGCCGGGCTCGG
CGCGGCGGCCCTGATCTGCTTCGCCGTCCTGGTCCCGCCGGTCGGATCGCGAACCTCGGAACGGGTGGACCTGCTCGGTG
CGGTCGGTCTGGCGGGCGGCCTGACCACGCTGCTGCTGGCGATCTCCAAGGGGCAGACCTGGGGGTGGACCAGCACGACG
ACGGTGAGCCTGTTCGCTGCCTCACCCGTCATCTTCGCGGTCTTCGCCTGGTGGCAGCTGCGTGCGCCCGCACCGATCGT
CGACCTGCGCACCACGGTCCGTCGGCCGGTGCTGACGACGAACCTCGCATCGGTGGGCGTGGGCTTCGGCCTGTTCGCGT
TGTCGCTCGTCGCACCGCAGGTGCTCGAACTGCCGACGCAGACCGGGTACGGGCTCGGGCAGTCGATGCTGCACGCAGGT
CTGTGGATGGCGCCCGGCGGGCTGGCGATGATGGTGTCCGCACCGATCGCCGCGCGGATCGCGGCGGTCACCGGACCCCG
GCTCACCCTCGTCATCGGATGCGCGATCATCTCGGTGTCCTACCTGGCCGGCCTCCAACTCCTGGACAGTCCCGTGGAGG
TGCTGATCCTCAATGTCGCGGTCAGCGTCGGGGTCGGATTCGCATTCGCCTCGTTGCCCGCCCTGATCAACGCGGCGGTT
CCGATCGCGGAGACCGCCGCTGCCAACGGCATCAACGCCCTGGCCCGGTCCCTGGGAACCTCGGTTTCCAGCGCCGTGAT
GGGCGCGGTGCTGGCCGGGATGACCACGTCGTTCGCCGGCCGGGTGCTCCCGTCGCTGGAGGGGTTCCACACCGCGCTGA
TCATCGCCGCCTGCGCGGCGGGCGTGGCGGGGCTGATCGCGCTGGCCATCCCGAAACCCGCTCCCGCGATCGCGCAGGTG
CACTCCGAACCGGGTCCCCCCGTGCACGATCTCGAGGCGGTGCTGACGCGACTGGGCCGGCATTCCGCACTGGGCACTTA
CGCCGACGGCACGTCGACGCCGTTCCTCGGGCGCCGGACCTACGTGCTGCTGACCCATCTCGAGGAGGCCGGGCCCGCAT
CGGTCGAGGAGATCGCCGACGCGCTGGGCGTCGATGCCGCGACGGTGGGCAGTGAGGCGTTCGTCATGCTACGCGACGGT
CTCGTCGCACCGGTGGCGCAGGACAGCCCACCCGCGTGGTCGGGGCGCACGCCACGCTTCGCGCTCACCGTGGGAGGCCG
GGATCGCCTGCGGCGGCAGCGGTCTCACAAGGTGGCGGGGTTGCGCCGCGCGGTCGACGGCTGGGACCACGCCGACGTCG
AGGCGTTGGTCGGTTACGTCACTCGGCTGAGCGACGACATCGACGGTGCCCGCCGGGGCGTCCGGCCGGTCACAGGCCGA
AGCGCGCCTTGA

Upstream 100 bases:

>100_bases
CGCGCTCGCCCAGCTGGTCCCGGCGCTACGGGAGCTCAGCGGCTGAGATCACGCCGCCGCGAGGTTTTAGATAGATAACC
TAATGGGTAGCATCCCCGTC

Downstream 100 bases:

>100_bases
GGTTCTTGGTCTGGTAGTGCTCGACGATGATGCCGAGCAGCGGGATCGTGCCGGCGAGCAGCACGCCGATGGTCTTGCCG
ATCGGCCAGCGCACCTTCAC

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 643; Mature: 642

Protein sequence:

>643_residues
MARHGVETSAADAAAVAARVRPNVLVAVLAAAGISVSLMQTLIIPLIPELPTLLRTGPANASWAITATLLTAAVATPLFG
RLGDIYGPKPVLMTCAALLTAGSVIAAVSTSLVPVIVGRGLQGFGMPIIPLGISVLRAAVPADRVGSAMGIMSASLGVGG
ALGLPLSAVIAQNFNWHVLFWFAAGLGAAALICFAVLVPPVGSRTSERVDLLGAVGLAGGLTTLLLAISKGQTWGWTSTT
TVSLFAASPVIFAVFAWWQLRAPAPIVDLRTTVRRPVLTTNLASVGVGFGLFALSLVAPQVLELPTQTGYGLGQSMLHAG
LWMAPGGLAMMVSAPIAARIAAVTGPRLTLVIGCAIISVSYLAGLQLLDSPVEVLILNVAVSVGVGFAFASLPALINAAV
PIAETAAANGINALARSLGTSVSSAVMGAVLAGMTTSFAGRVLPSLEGFHTALIIAACAAGVAGLIALAIPKPAPAIAQV
HSEPGPPVHDLEAVLTRLGRHSALGTYADGTSTPFLGRRTYVLLTHLEEAGPASVEEIADALGVDAATVGSEAFVMLRDG
LVAPVAQDSPPAWSGRTPRFALTVGGRDRLRRQRSHKVAGLRRAVDGWDHADVEALVGYVTRLSDDIDGARRGVRPVTGR
SAP

Sequences:

>Translated_643_residues
MARHGVETSAADAAAVAARVRPNVLVAVLAAAGISVSLMQTLIIPLIPELPTLLRTGPANASWAITATLLTAAVATPLFG
RLGDIYGPKPVLMTCAALLTAGSVIAAVSTSLVPVIVGRGLQGFGMPIIPLGISVLRAAVPADRVGSAMGIMSASLGVGG
ALGLPLSAVIAQNFNWHVLFWFAAGLGAAALICFAVLVPPVGSRTSERVDLLGAVGLAGGLTTLLLAISKGQTWGWTSTT
TVSLFAASPVIFAVFAWWQLRAPAPIVDLRTTVRRPVLTTNLASVGVGFGLFALSLVAPQVLELPTQTGYGLGQSMLHAG
LWMAPGGLAMMVSAPIAARIAAVTGPRLTLVIGCAIISVSYLAGLQLLDSPVEVLILNVAVSVGVGFAFASLPALINAAV
PIAETAAANGINALARSLGTSVSSAVMGAVLAGMTTSFAGRVLPSLEGFHTALIIAACAAGVAGLIALAIPKPAPAIAQV
HSEPGPPVHDLEAVLTRLGRHSALGTYADGTSTPFLGRRTYVLLTHLEEAGPASVEEIADALGVDAATVGSEAFVMLRDG
LVAPVAQDSPPAWSGRTPRFALTVGGRDRLRRQRSHKVAGLRRAVDGWDHADVEALVGYVTRLSDDIDGARRGVRPVTGR
SAP
>Mature_642_residues
ARHGVETSAADAAAVAARVRPNVLVAVLAAAGISVSLMQTLIIPLIPELPTLLRTGPANASWAITATLLTAAVATPLFGR
LGDIYGPKPVLMTCAALLTAGSVIAAVSTSLVPVIVGRGLQGFGMPIIPLGISVLRAAVPADRVGSAMGIMSASLGVGGA
LGLPLSAVIAQNFNWHVLFWFAAGLGAAALICFAVLVPPVGSRTSERVDLLGAVGLAGGLTTLLLAISKGQTWGWTSTTT
VSLFAASPVIFAVFAWWQLRAPAPIVDLRTTVRRPVLTTNLASVGVGFGLFALSLVAPQVLELPTQTGYGLGQSMLHAGL
WMAPGGLAMMVSAPIAARIAAVTGPRLTLVIGCAIISVSYLAGLQLLDSPVEVLILNVAVSVGVGFAFASLPALINAAVP
IAETAAANGINALARSLGTSVSSAVMGAVLAGMTTSFAGRVLPSLEGFHTALIIAACAAGVAGLIALAIPKPAPAIAQVH
SEPGPPVHDLEAVLTRLGRHSALGTYADGTSTPFLGRRTYVLLTHLEEAGPASVEEIADALGVDAATVGSEAFVMLRDGL
VAPVAQDSPPAWSGRTPRFALTVGGRDRLRRQRSHKVAGLRRAVDGWDHADVEALVGYVTRLSDDIDGARRGVRPVTGRS
AP

Specific function: Proton-dependent transporter. May mediate the efflux of lincomycin [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. EmrB family [H]

Homologues:

Organism=Escherichia coli, GI87081983, Length=395, Percent_Identity=28.3544303797468, Blast_Score=99, Evalue=1e-21,
Organism=Escherichia coli, GI1788710, Length=319, Percent_Identity=24.4514106583072, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1789042, Length=415, Percent_Identity=23.3734939759036, Blast_Score=67, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004638
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR001411 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 65430; Mature: 65299

Theoretical pI: Translated: 9.76; Mature: 9.76

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARHGVETSAADAAAVAARVRPNVLVAVLAAAGISVSLMQTLIIPLIPELPTLLRTGPAN
CCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHCCCCC
ASWAITATLLTAAVATPLFGRLGDIYGPKPVLMTCAALLTAGSVIAAVSTSLVPVIVGRG
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LQGFGMPIIPLGISVLRAAVPADRVGSAMGIMSASLGVGGALGLPLSAVIAQNFNWHVLF
CCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCEEHH
WFAAGLGAAALICFAVLVPPVGSRTSERVDLLGAVGLAGGLTTLLLAISKGQTWGWTSTT
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
TVSLFAASPVIFAVFAWWQLRAPAPIVDLRTTVRRPVLTTNLASVGVGFGLFALSLVAPQ
EEEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
VLELPTQTGYGLGQSMLHAGLWMAPGGLAMMVSAPIAARIAAVTGPRLTLVIGCAIISVS
HHHCCCCCCCCCCHHHHHCCCCCCCCCCEEHHHCCHHHHHHHHCCCCHHHHHHHHHHHHH
YLAGLQLLDSPVEVLILNVAVSVGVGFAFASLPALINAAVPIAETAAANGINALARSLGT
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCHHHHHHHHHCC
SVSSAVMGAVLAGMTTSFAGRVLPSLEGFHTALIIAACAAGVAGLIALAIPKPAPAIAQV
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
HSEPGPPVHDLEAVLTRLGRHSALGTYADGTSTPFLGRRTYVLLTHLEEAGPASVEEIAD
CCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEEHHHCCCCCHHHHHH
ALGVDAATVGSEAFVMLRDGLVAPVAQDSPPAWSGRTPRFALTVGGRDRLRRQRSHKVAG
HHCCCHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHH
LRRAVDGWDHADVEALVGYVTRLSDDIDGARRGVRPVTGRSAP
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
ARHGVETSAADAAAVAARVRPNVLVAVLAAAGISVSLMQTLIIPLIPELPTLLRTGPAN
CCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHCCCCC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HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]